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Rattus norvegicus (Norway rat) Negative regulation of the PI3K/AKT network (provided by Reactome)

88 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.

Gene Symbol	Full Name
Irs1	insulin receptor substrate 1
Met	MET proto-oncogene, receptor tyrosine kinase
Nrg4	neuregulin 4
Trib3	tribbles pseudokinase 3
Fgf8	fibroblast growth factor 8
Pdgfra	platelet derived growth factor receptor alpha
Grb2	growth factor receptor bound protein 2
Kit	KIT proto-oncogene receptor tyrosine kinase
Ppp2r5e	protein phosphatase 2 regulatory subunit B', epsilon
Btc	betacellulin
Erbb4	erb-b2 receptor tyrosine kinase 4
Fgf7	fibroblast growth factor 7
Pip5k1b	phosphatidylinositol-4-phosphate 5-kinase type 1 beta
Hgf	hepatocyte growth factor
Fgf20	fibroblast growth factor 20
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1
LOC103694903	serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Ppp2r1b	protein phosphatase 2 scaffold subunit A beta
Cd80	Cd80 molecule
Cd28	Cd28 molecule
Pdgfrb	platelet derived growth factor receptor beta
Nrg1	neuregulin 1
Egf	epidermal growth factor
Ereg	epiregulin
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1
Mapk3	mitogen activated protein kinase 3
Icos	inducible T-cell co-stimulator
Fgf10	fibroblast growth factor 10
Lck	LCK proto-oncogene, Src family tyrosine kinase
Cd19	CD19 molecule
Mapk1	mitogen activated protein kinase 1
Fgf2	fibroblast growth factor 2
Irs2	insulin receptor substrate 2
Pip5k1c	phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
Fgf6	fibroblast growth factor 6
Ier3	immediate early response 3
Ins2	insulin 2
Pik3r2	phosphoinositide-3-kinase regulatory subunit 2
Frs2	fibroblast growth factor receptor substrate 2
Fgf3	fibroblast growth factor 3
Erbb3	erb-b2 receptor tyrosine kinase 3
Fgf19	fibroblast growth factor 19
Vav1	vav guanine nucleotide exchange factor 1
Pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Ptpn11	protein tyrosine phosphatase, non-receptor type 11
Fgfr4	fibroblast growth factor receptor 4
Gab1	GRB2-associated binding protein 1
Fgf17	fibroblast growth factor 17
Pik3cd	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Pdgfb	platelet derived growth factor subunit B
Fgf5	fibroblast growth factor 5
Nrg2	neuregulin 2
Pik3cb	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Fgfr3	fibroblast growth factor receptor 3
Cd86	CD86 molecule
Hbegf	heparin-binding EGF-like growth factor
Trat1	T cell receptor associated transmembrane adaptor 1
Pten	phosphatase and tensin homolog
Pip4k2c	phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
Kitlg	KIT ligand
Fgf9	fibroblast growth factor 9
Egfr	epidermal growth factor receptor
Ppp2r5b	protein phosphatase 2, regulatory subunit B', beta
Fgf22	fibroblast growth factor 22
Src	SRC proto-oncogene, non-receptor tyrosine kinase
Ppp2r1a	protein phosphatase 2 scaffold subunit A alpha
LOC685590	similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)
Pik3r1	phosphoinositide-3-kinase regulatory subunit 1
Fgf23	fibroblast growth factor 23
LOC102552659	receptor tyrosine-protein kinase erbB-2-like
Pip4k2b	phosphatidylinositol-5-phosphate 4-kinase type 2 beta
Insr	insulin receptor
Them4	thioesterase superfamily member 4
Fgfr2	fibroblast growth factor receptor 2
Pip5k1a	phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
Pdgfa	platelet derived growth factor subunit A
LOC100910178	pro-epidermal growth factor-like
Fyn	FYN proto-oncogene, Src family tyrosine kinase
Akt1	AKT serine/threonine kinase 1
Fgf1	fibroblast growth factor 1
Ppp2r5c	protein phosphatase 2, regulatory subunit B', gamma
Ppp2r5a	protein phosphatase 2, regulatory subunit B', alpha
Fgf4	fibroblast growth factor 4
Fgf16	fibroblast growth factor 16
Ins1	insulin 1
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isozyme
Ppp2cb	protein phosphatase 2 catalytic subunit beta
Fgfr1	Fibroblast growth factor receptor 1

ORF

Species Summary
- Rattus norvegicus
  - Reactome
    - Negative regulation of the PI3K/AKT network

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