Mapk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mapk3
Entrez Gene ID	50689
Full Name	mitogen activated protein kinase 3
Synonyms	ERK1,ERT2,Erk-1,Esrk1,MAPK1,MNK1,Prkm3,p44,p44erk1,p44mapk
General protein information	Preferred Names mitogen activated protein kinase 3 Names mitogen-activated protein kinase 3 MAP kinase 1 MAP kinase 3 MAP kinase isoform p44 MAPK 1 MAPK 3 extracellular signal-regulated kinase 1 insulin-stimulated MAP2 kinase microtubule-associated protein 2 kinase mitogen-activated 3 mitogen-activated protein kinase 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q36
Summary	kinase involved in intracellular signalling; component of Mapk signalling pathway [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017347.2	NP_059043.1	mitogen-activated protein kinase 3

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os02g0148100	NP_001045889.1
Pan troglodytes (chimpanzee)	MAPK3	XP_510921.3
Canis lupus familiaris (dog)	LOC479790	NP_001238964.1
Bos taurus (cattle)	MAPK3	NP_001103488.1
Danio rerio (zebrafish)	mapk3	NP_958915.1
Arabidopsis thaliana (thale cress)	MPK2	NP_564746.1
Rattus norvegicus (Norway rat)	Mapk3	NP_059043.1
Arabidopsis thaliana (thale cress)	MPK1	NP_001031017.1
Eremothecium gossypii	AGOS_AFR019W	NP_985566.1
Oryza sativa (rice)	Os06g0699400	NP_001058471.1
Neurospora crassa	NCU02393	XP_959713.2
Macaca mulatta (Rhesus monkey)	MAPK3	XP_002802489.1
Mus musculus (house mouse)	Mapk3	NP_036082.1
Saccharomyces cerevisiae (baker's yeast)	FUS3	NP_009537.1
Kluyveromyces lactis	KLLA0E10539g	XP_454426.1
Schizosaccharomyces pombe (fission yeast)	spk1	NP_594009.1
Magnaporthe oryzae (rice blast fungus)	MGG_09565	XP_003712175.1
Homo sapiens (human)	MAPK3	NP_002737.2

Gene Ontology
Bibliography

Related articles in PubMed

Nav1.7 via Promotion of ERK in the Trigeminal Ganglion Plays an Important Role in the Induction of Pulpitis Inflammatory Pain.
Sun S, Sun J, Jiang W, Wang W, Ni L
BioMed research international20196973932(2019)

Matrix stiffness regulates the differentiation of tendon-derived stem cells through FAK-ERK1/2 activation.
Liu C, Luo JW, Liang T, Lin LX, Luo ZP, Zhuang YQ, Sun YL
Experimental cell research373(1-2)62-70(2018 12)

The Role of Extracellular Signal-Regulated Kinases (ERK) in the Regulation of mGlu5 Receptors in Neurons.
Jin DZ, Mao LM, Wang JQ
Journal of molecular neuroscience : MN66(4)629-638(2018 Dec)

Physical exercise promotes proliferation and differentiation of endogenous neural stem cells via ERK in rats with cerebral infarction.
Liu W, Wu W, Lin G, Cheng J, Zeng Y, Shi Y
Molecular medicine reports18(2)1455-1464(2018 Aug)

Spinal glucocorticoid receptor‑regulated chronic morphine tolerance may be through extracellular signal‑regulated kinase 1/2.
Zhai ML, Chen Y, Liu C, Wang JB, Yu YH
Molecular medicine reports18(1)1074-1080(2018 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mapk3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mapk3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13279	NM_017347.2 Latest version!	Rattus norvegicus mitogen activated protein kinase 3 (Mapk3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mapk3 ( NM_017347.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_059043.1 Rattus norvegicus mitogen activated protein kinase 3 (Mapk3), mRNA.

Price & Availability↑

CloneID	ORa13279
Clone ID Related Accession (Same CDS sequence)	NM_017347.2
Accession Version	NM_017347.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575648000000
Organism	Rattus norvegicus(Norway rat)
Product	mitogen-activated protein kinase 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from S46779.1. On or before Jun 25, 2006 this sequence version replaced XM_001079997.1, NM_017347.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: S46779.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCGG CGGCGGCGGC TCCGGGGGGC GGGGGCGGGG AGCCCAGGGG AACTGCTGGG 
GTCGTCCCGG TGGTCCCCGG GGAGGTGGAG GTGGTGAAGG GGCAGCCATT CGACGTGGGC 
CCACGCTACA CGCAGCTGCA GTACATCGGC GAGGGCGCGT ACGGCATGGT CAGCTCAGCA 
TATGACCACG TGCGCAAGAC CAGAGTGGCT ATCAAGAAGA TCAGCCCCTT CGAGCATCAA 
ACCTACTGTC AGCGCACGCT GAGAGAAATC CAGATCTTGC TCGGATTCCG CCATGAGAAT 
GTCATAGGCA TCCGAGACAT CCTCAGAGCA CCCACCCTGG AAGCCATGAG AGATGTTTAC 
ATTGTTCAGG ACCTCATGGA GACGGACCTG TACAAGCTGC TAAAGAGCCA GCAGCTGAGC 
AATGACCACA TCTGCTACTT CCTCTACCAG ATCCTCCGGG GCCTCAAGTA CATACACTCG 
GCCAATGTGC TGCACCGGGA CCTGAAGCCC TCCAATCTGC TTATCAACAC CACCTGCGAC 
CTTAAGATCT GTGATTTTGG CCTTGCCCGG ATTGCTGACC CTGAGCACGA CCACACTGGC 
TTTCTGACCG AGTATGTGGC CACACGCTGG TACCGAGCCC CAGAGATCAT GCTTAACTCC 
AAGGGCTACA CCAAATCCAT TGACATCTGG TCTGTGGGCT GCATTCTGGC TGAGATGCTC 
TCCAACCGGC CTATCTTCCC CGGCAAGCAC TACCTGGACC AGCTCAACCA CATTCTAGGT 
ATACTGGGTT CCCCATCCCA AGAGGACCTA AATTGTATCA TTAACATGAA GGCCCGAAAC 
TACCTACAGT CTCTGCCCTC TAAAACCAAG GTGGCTTGGG CCAAGCTTTT TCCCAAATCT 
GACTCCAAAG CTCTTGACCT GCTGGACCGG ATGTTAACCT TTAACCCAAA CAAGCGCATC 
ACAGTAGAGG AAGCACTGGC TCACCCTTAC CTGGAACAGT ACTATGATCC GACAGATGAA 
CCAGTGGCTG AGGAGCCATT CACCTTTGAC ATGGAGCTGG ATGATCTCCC CAAGGAGCGG 
CTGAAGGAGC TGATCTTCCA AGAGACAGCC CGCTTCCAGC CAGGGGCACC AGAGGCCCCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059043.1
CDS	25..1167
Translation	MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLGFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERLKELIFQETARFQPGAPEAP

Target ORF information:

RefSeq Version	NM_017347.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitogen activated protein kinase 3 (Mapk3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017347.2

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCGGC TCCGGGGGGC GGGGGCGGGG AGCCCAGGGG AACTGCTGGG 
GTCGTCCCGG TGGTCCCCGG GGAGGTGGAG GTGGTGAAGG GGCAGCCATT CGACGTGGGC 
CCACGCTACA CGCAGCTGCA GTACATCGGC GAGGGCGCGT ACGGCATGGT CAGCTCAGCA 
TATGACCACG TGCGCAAGAC CAGAGTGGCT ATCAAGAAGA TCAGCCCCTT CGAGCATCAA 
ACCTACTGTC AGCGCACGCT GAGAGAAATC CAGATCTTGC TCGGATTCCG CCATGAGAAT 
GTCATAGGCA TCCGAGACAT CCTCAGAGCA CCCACCCTGG AAGCCATGAG AGATGTTTAC 
ATTGTTCAGG ACCTCATGGA GACGGACCTG TACAAGCTGC TAAAGAGCCA GCAGCTGAGC 
AATGACCACA TCTGCTACTT CCTCTACCAG ATCCTCCGGG GCCTCAAGTA CATACACTCG 
GCCAATGTGC TGCACCGGGA CCTGAAGCCC TCCAATCTGC TTATCAACAC CACCTGCGAC 
CTTAAGATCT GTGATTTTGG CCTTGCCCGG ATTGCTGACC CTGAGCACGA CCACACTGGC 
TTTCTGACCG AGTATGTGGC CACACGCTGG TACCGAGCCC CAGAGATCAT GCTTAACTCC 
AAGGGCTACA CCAAATCCAT TGACATCTGG TCTGTGGGCT GCATTCTGGC TGAGATGCTC 
TCCAACCGGC CTATCTTCCC CGGCAAGCAC TACCTGGACC AGCTCAACCA CATTCTAGGT 
ATACTGGGTT CCCCATCCCA AGAGGACCTA AATTGTATCA TTAACATGAA GGCCCGAAAC 
TACCTACAGT CTCTGCCCTC TAAAACCAAG GTGGCTTGGG CCAAGCTTTT TCCCAAATCT 
GACTCCAAAG CTCTTGACCT GCTGGACCGG ATGTTAACCT TTAACCCAAA CAAGCGCATC 
ACAGTAGAGG AAGCACTGGC TCACCCTTAC CTGGAACAGT ACTATGATCC GACAGATGAA 
CCAGTGGCTG AGGAGCCATT CACCTTTGAC ATGGAGCTGG ATGATCTCCC CAAGGAGCGG 
CTGAAGGAGC TGATCTTCCA AGAGACAGCC CGCTTCCAGC CAGGGGCACC AGAGGCCCCC 
TAA