Resources

List by Alphabet: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

a Related Biological Terms:

complementary base

The purine that can form hydrogen bonds with a pyrimidine, and vice versa, in a double-stranded polynucleotide, e.g. G with C and A with T. (see also complementary)

complementation cloning

A method for identification of a DNA fragment and selection of the defective cell line upon which it confers resistance to a selective pressure, e.g. cells that are hypersensitive to ionizing radiation. Fractions of normal genomic cDNA are screened for ability to confer resistance on cells into which they are introduced. Different lines of defective cells that represent discrete genetic defects may be associated with different cDNA fragments. Learn more about sgRNA.

complex carbohydrate

An oligomer or higher polymer of more than one kind of sugar moiety, or a glycoside formed with a non-sugar compound. (see also glycolipid; glycoprotein; glycoside; heteropolysaccharide; proteoglycan (mucopolysaccharide)) Related tool: molecular biology tools

complex-type carbohydrate

One type of glycoprotein moiety that is attached to the β-amide nitrogen of an asparagine residue (N-linked) and which may contain sialic acid residues at the non-reducing ends. (see also hybrid-type carbohydrate; high-mannose-type carbohydrate)

concatenate (catenane)

A structure formed by two or more interlinked closed circular (cc)DNAs; formation occurs between the rapid replication of a ccDNA and the slow nicking of one of the ccDNAs to release it from the others.

concatenation cDNA sequencing (CCS)

(see double adaptor method)

concerted reaction

A chemical or enzymic reaction in which several operations, e.g. attachment of an incoming group and departure of a leaving group, occur simultaneously and on opposite sides of the reaction centre.

condensation reaction

The formation of a carbon-carbon, carbon-nitrogen or carbon-sulphur bond.

conditional expression

The technique of constructing cell lines, or transgenic animals, in which the expression of a gene may be controlled by the level of an exogenous compound. One such system, tet-on, involves a plasmid with the Escherichia coli tetracycline-dependent operator upstream from the coding sequence of the targeted gene: in the presence of a tetracycline, the gene is expressed. In the tet-off system, a regulator plasmid is also present, and encodes the tetracylcine-controlled transactivator protein, which brings the tetracycline operator into proximity with the promoter sequence of the gene and allows gene expression to proceed. If, however, a tetracylcine is present, expression is interrupted.Cohen-Tannoudji, M. and Babinet, C. (1998) Mol. Hum. Reprod. 4, 929-938; Porter, A. (1998) Trends genet. 14, 73-79 Related service: cell line development

configuration

An arrangement in space at an asymmetrical centre. (see also alpha (α)-configuration; conformation)

< 45 46 47 48 49 50 51 52 53 54 55 > Total Pages 251

If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: website@genscript.com

If your term is adopted, we will send 1,000 EzCoupon points to your GenScript account.