Ezr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ezr
Entrez Gene ID	54319
Full Name	ezrin
Synonyms	Vil2
General protein information	Preferred Names ezrin Names ezrin cytovillin p81 villin-2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q11
Summary	connects the microvillar cytoskeleton to the plasma membrane [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019357.1	NP_062230.1	ezrin

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EZR	XP_541173.2
Macaca mulatta (Rhesus monkey)	EZR	XP_002803901.1
Pan troglodytes (chimpanzee)	EZR	XP_003311612.1
Xenopus tropicalis (tropical clawed frog)	ezr	NP_001025629.1
Danio rerio (zebrafish)	ezra	NP_001018326.1
Mus musculus (house mouse)	Ezr	NP_033536.2
Rattus norvegicus (Norway rat)	Ezr	NP_062230.1
Gallus gallus (chicken)	EZR	NP_990216.1
Homo sapiens (human)	EZR	NP_003370.2
Bos taurus (cattle)	EZR	NP_776642.1
Danio rerio (zebrafish)	ezrb	NP_001025456.1

Gene Ontology
Bibliography

Related articles in PubMed

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
Liu X, Salokas K, Tamene F, Jiu Y, Weldatsadik RG, Öhman T, Varjosalo M
Nature communications9(1)1188(2018 03)

A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells.
Dukic AR, Haugen LH, Pidoux G, Leithe E, Bakke O, Taskén K
Cellular signalling321-11(2017 04)

[The transfection of lentiviral siRNA vectors targeting ezrin, radixin and moesin facilitates influenza virus replication in primary pulmonary microvascular endothelial cells].
Wu Y, Zhang S, Zhang C, Xuan Z, Li S, Gao Y, Hu Y
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology31(4)456-61(2015 Apr)

Plasmodium vivax inhibits erythroid cell growth through altered phosphorylation of the cytoskeletal protein ezrin.
Panichakul T, Ponnikorn S, Roytrakul S, Paemanee A, Kittisenachai S, Hongeng S, Udomsangpetch R
Malaria journal14138(2015 Mar)

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.
Doi Y, Itoh M, Yonemura S, Ishihara S, Takano H, Noda T, Tsukita S
The Journal of biological chemistry274(4)2315-21(1999 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ezr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ezr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12622	NM_019357.1 Latest version!	Rattus norvegicus ezrin (Ezr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ezr ( NM_019357.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062230.1 Rattus norvegicus ezrin (Ezr), mRNA.

Price & Availability↑

CloneID	ORa12622
Clone ID Related Accession (Same CDS sequence)	NM_019357.1
Accession Version	NM_019357.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1761bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	ezrin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081958.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC081958.1, AY428869.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCCCAAGC CAATCAACGT CCGCGTGACC ACCATGGATG CAGAGCTGGA GTTTGCCATC 
CAGCCAAACA CCACCGGGAA GCAGCTCTTT GATCAGGTGG TAAAGACCAT TGGCCTCCGG 
GAAGTGTGGT ACTTCGGCCT CCAGTATGTA GACAATAAAG GATTTCCTAC CTGGCTGAAA 
CTTGATAAAA AGGTCTCTGC ACAGGAGGTT CGAAAGGAGA ACCCTGTCCA GTTCAAATTC 
CGGGCCAAGT TCTACCCCGA GGATGTGGCT GATGAGCTCA TCCAGGACAT CACACAGAAG 
CTCTTCTTCC TGCAAGTCAA GGAAGGGATC CTCAGCGATG AGATCTACTG CCCCCCAGAG 
ACAGCCGTGC TCCTGGGGTC CTATGCCGTT CAGGCCAAGT TCGGAGATTA TAACAAGGAA 
ATGCACAAGT CTGGGTACCT CAGCTCCGAG AGACTTATCC CTCAGAGAGT CATGGACCAG 
CACAAGCTCA GCAGGGACCA GTGGGAGGAC CGGATCCAGG TGTGGCACGC AGAACACCGA 
GGGATGCTCA AGGACAGTGC TATGCTCGAA TACCTGAAGA TTGCCCAGGA CCTGGAAATG 
TATGGGATCA ACTATTTCGA GATCAAAAAC AAGAAAGGAA CAGATCTTTG GCTTGGAGTG 
GATGCCCTTG GACTTAACAT TTATGAGAAA GATGACAAGT TGACCCCGAA GATCGGCTTC 
CCTTGGAGTG AAATCAGGAA CATCTCTTTC AACGACAAGA AGTTTGTCAT CAAGCCCATC 
GACAAGAAGG CTCCTGACTT CGTGTTCTAC GCTCCCCGCC TGAGAATTAA CAAGCGGATT 
CTGCAGCTCT GCATGGGGAA CCACGAGCTG TACATGCGCC GCAGGAAGCC CGACACCATC 
GAGGTGCAGC AGATGAAGGC CCAGGCTCGG GAGGAGAAGC ACCAGAAGCA GCTGGAGCGA 
CAACAGTTGG AAACCGAGAA GAAGAGGAGA GAAACTGTAG AGAGAGAAAA GGAACAGATG 
CTCCGGGAGA AGGAAGAGCT GATGCTTCGG CTGCAGGACT TTGAGCAGAA GACCAAGAGG 
GCAGAGAAAG AGCTCTCCGA GCAGATTGAG AAGGCCCTCC AGCTGGAGGA AGAGAGGAGG 
CGAGCCCAGG AGGAGGCTGA ACGTCTGGAG GCCGACCGCA TGGCCGCCCT GCGGGCCAAG 
GAAGAACTGG AGAGACAGGC ACAGGATCAG ATAAAGAGCC AGGAGCAGCT GGCTGCAGAG 
CTGGCAGAGT ATACTGCCAA GATTGCCCTG CTGGAGGAGG CACGGAGGCG CAAGGAGGAC 
GAGGTGGAGG AGTGGCAGCA CCGGGCTAAA GAGGCCCAGG ACGACCTGGT GAAGACCAAA 
GAGGAGCTGC ACCTGGTGAT GACGGCTCCC CCGCCCCCAC CCCCGCCCGT GTACGAGCCC 
GTGAATTACC ACGTGCAGGA GGGGCTGCAG GATGAGGGAG CAGAGCCCAT GGGCTACAGT 
GCCGAGCTCT CCAGCGAGGG CATCCTGGAC GACCGTAACG AGGAGAAGCG GATCACCGAG 
GCAGAGAAGA ACGAGCGCGT GCAGCGGCAG CTGCTGACTC TGAGCAATGA GTTGTCCCAG 
GCCCGGGATG AGAATAAGAG GACCCACAAT GACATCATCC ACAATGAGAA CATGCGGCAA 
GGCCGGGACA AGTATAAGAC GCTGCGGCAG ATCAGGCAGG GCAACACCAA GCAGCGCATC 
GACGAGTTTG AGGCCATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062230.1
CDS	483..2243
Translation	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPVQFKFRAKFYPEDVADELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEMHKSGYLSSERLIPQRVMDQHKLSRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMLREKEELMLRLQDFEQKTKRAEKELSEQIEKALQLEEERRRAQEEAERLEADRMAALRAKEELERQAQDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVNYHVQEGLQDEGAEPMGYSAELSSEGILDDRNEEKRITEAEKNERVQRQLLTLSNELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM

Target ORF information:

RefSeq Version	NM_019357.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ezrin (Ezr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019357.1

ORF Insert Sequence:

ATGCCCAAGC CAATCAACGT CCGCGTGACC ACCATGGATG CAGAGCTGGA GTTTGCCATC 
CAGCCAAACA CCACCGGGAA GCAGCTCTTT GATCAGGTGG TAAAGACCAT TGGCCTCCGG 
GAAGTGTGGT ACTTCGGCCT CCAGTATGTA GACAATAAAG GATTTCCTAC CTGGCTGAAA 
CTTGATAAAA AGGTCTCTGC ACAGGAGGTT CGAAAGGAGA ACCCTGTCCA GTTCAAATTC 
CGGGCCAAGT TCTACCCCGA GGATGTGGCT GATGAGCTCA TCCAGGACAT CACACAGAAG 
CTCTTCTTCC TGCAAGTCAA GGAAGGGATC CTCAGCGATG AGATCTACTG CCCCCCAGAG 
ACAGCCGTGC TCCTGGGGTC CTATGCCGTT CAGGCCAAGT TCGGAGATTA TAACAAGGAA 
ATGCACAAGT CTGGGTACCT CAGCTCCGAG AGACTTATCC CTCAGAGAGT CATGGACCAG 
CACAAGCTCA GCAGGGACCA GTGGGAGGAC CGGATCCAGG TGTGGCACGC AGAACACCGA 
GGGATGCTCA AGGACAGTGC TATGCTCGAA TACCTGAAGA TTGCCCAGGA CCTGGAAATG 
TATGGGATCA ACTATTTCGA GATCAAAAAC AAGAAAGGAA CAGATCTTTG GCTTGGAGTG 
GATGCCCTTG GACTTAACAT TTATGAGAAA GATGACAAGT TGACCCCGAA GATCGGCTTC 
CCTTGGAGTG AAATCAGGAA CATCTCTTTC AACGACAAGA AGTTTGTCAT CAAGCCCATC 
GACAAGAAGG CTCCTGACTT CGTGTTCTAC GCTCCCCGCC TGAGAATTAA CAAGCGGATT 
CTGCAGCTCT GCATGGGGAA CCACGAGCTG TACATGCGCC GCAGGAAGCC CGACACCATC 
GAGGTGCAGC AGATGAAGGC CCAGGCTCGG GAGGAGAAGC ACCAGAAGCA GCTGGAGCGA 
CAACAGTTGG AAACCGAGAA GAAGAGGAGA GAAACTGTAG AGAGAGAAAA GGAACAGATG 
CTCCGGGAGA AGGAAGAGCT GATGCTTCGG CTGCAGGACT TTGAGCAGAA GACCAAGAGG 
GCAGAGAAAG AGCTCTCCGA GCAGATTGAG AAGGCCCTCC AGCTGGAGGA AGAGAGGAGG 
CGAGCCCAGG AGGAGGCTGA ACGTCTGGAG GCCGACCGCA TGGCCGCCCT GCGGGCCAAG 
GAAGAACTGG AGAGACAGGC ACAGGATCAG ATAAAGAGCC AGGAGCAGCT GGCTGCAGAG 
CTGGCAGAGT ATACTGCCAA GATTGCCCTG CTGGAGGAGG CACGGAGGCG CAAGGAGGAC 
GAGGTGGAGG AGTGGCAGCA CCGGGCTAAA GAGGCCCAGG ACGACCTGGT GAAGACCAAA 
GAGGAGCTGC ACCTGGTGAT GACGGCTCCC CCGCCCCCAC CCCCGCCCGT GTACGAGCCC 
GTGAATTACC ACGTGCAGGA GGGGCTGCAG GATGAGGGAG CAGAGCCCAT GGGCTACAGT 
GCCGAGCTCT CCAGCGAGGG CATCCTGGAC GACCGTAACG AGGAGAAGCG GATCACCGAG 
GCAGAGAAGA ACGAGCGCGT GCAGCGGCAG CTGCTGACTC TGAGCAATGA GTTGTCCCAG 
GCCCGGGATG AGAATAAGAG GACCCACAAT GACATCATCC ACAATGAGAA CATGCGGCAA 
GGCCGGGACA AGTATAAGAC GCTGCGGCAG ATCAGGCAGG GCAACACCAA GCAGCGCATC 
GACGAGTTTG AGGCCATGTA G