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About the Signaling by VEGF pathway
In normal development vascular endothelial growth factors (VEGFs) are crucial regulators of vascular development during embryogenesis (vasculogenesis) and blood-vessel formation in the adult (angiogenesis).
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| Gene Symbol | Full Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ANGPT1 | angiopoietin 1 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| RHOA | ras homolog family member A |
| ARRB1 | arrestin, beta 1 |
| ARRB2 | arrestin, beta 2 |
| AXL | AXL receptor tyrosine kinase |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTC | betacellulin |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CDC42 | cell division cycle 42 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| MAPK14 | mitogen-activated protein kinase 14 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CSK | c-src tyrosine kinase |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYBB | cytochrome b-245, beta polypeptide |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DOCK1 | dedicator of cytokinesis 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP6 | dual specificity phosphatase 6 |
| DUSP7 | dual specificity phosphatase 7 |
| DUSP8 | dual specificity phosphatase 8 |
| DUSP9 | dual specificity phosphatase 9 |
| EGF | epidermal growth factor |
| EGFR | epidermal growth factor receptor |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| EREG | epiregulin |
| PTK2B | protein tyrosine kinase 2 beta |
| FGA | fibrinogen alpha chain |
| FGB | fibrinogen beta chain |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGF3 | fibroblast growth factor 3 |
| FGF4 | fibroblast growth factor 4 |
| FGF5 | fibroblast growth factor 5 |
| FGF6 | fibroblast growth factor 6 |
| FGF7 | fibroblast growth factor 7 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FGF9 | fibroblast growth factor 9 |
| FGF10 | fibroblast growth factor 10 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FGG | fibrinogen gamma chain |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
| FLT1 | fms-related tyrosine kinase 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FN1 | fibronectin 1 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GRB2 | growth factor receptor-bound protein 2 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
| NCKAP1L | NCK-associated protein 1-like |
| NRG1 | neuregulin 1 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HSPB1 | heat shock 27kDa protein 1 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| IL2 | interleukin 2 |
| IL2RA | interleukin 2 receptor, alpha |
| IL2RB | interleukin 2 receptor, beta |
| IL2RG | interleukin 2 receptor, gamma |
| IL3 | interleukin 3 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| IL5 | interleukin 5 |
| IL5RA | interleukin 5 receptor, alpha |
| IRS1 | insulin receptor substrate 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGAV | integrin, alpha V |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| JAK1 | Janus kinase 1 |