ITGAV cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITGAV
Entrez Gene ID	3685
Full Name	integrin subunit alpha V
Synonyms	CD51,MSK8,VNRA,VTNR
General protein information	Preferred Names integrin subunit alpha V Names integrin alpha-V antigen identified by monoclonal antibody L230 integrin alphaVbeta3 integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) vitronectin receptor subunit alpha
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q32.1
Summary	The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015].
Disorder MIM:	193210

mRNA and Protein(s)

mRNA	Protein	Name
NM_002210.4	NP_002201.1	integrin alpha-V isoform 1 preproprotein
NM_001145000.2	NP_001138472.1	integrin alpha-V isoform 3 precursor
NM_001145000.3	NP_001138472.2	integrin alpha-V isoform 3 precursor
NM_002210.5	NP_002201.2	integrin alpha-V isoform 1 preproprotein
NM_001144999.2	NP_001138471.1	integrin alpha-V isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	ITGAV	NP_002201.1
Macaca mulatta (Rhesus monkey)	ITGAV	XP_001104012.1
Canis lupus familiaris (dog)	ITGAV	XP_850989.2
Bos taurus (cattle)	ITGAV	NP_776792.1
Danio rerio (zebrafish)	itgav	NP_001028893.1
Rattus norvegicus (Norway rat)	Itgav	XP_006234499.1
Gallus gallus (chicken)	ITGAV	NP_990770.1
Mus musculus (house mouse)	Itgav	NP_032428.2
Pan troglodytes (chimpanzee)	ITGAV	XP_515967.3
Xenopus tropicalis (tropical clawed frog)	itgav	NP_001116921.1

Gene Ontology
Bibliography

Related articles in PubMed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.
Nakamura K, Ikeuchi T, Nara K, Rhodes CS, Zhang P, Chiba Y, Kazuno S, Miura Y, Ago T, Arikawa-Hirasawa E, Mukouyama YS, Yamada Y
The Journal of cell biology218(10)3506-3525(2019 Oct)

Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling.
Takada YK, Yu J, Shimoda M, Takada Y
Journal of immunology (Baltimore, Md. : 1950)203(5)1383-1391(2019 Sep)

Hypoxia-driven paracrine osteopontin/integrin αvβ3 signaling promotes pancreatic cancer cell epithelial-mesenchymal transition and cancer stem cell-like properties by modulating forkhead box protein M1.
Cao J, Li J, Sun L, Qin T, Xiao Y, Chen K, Qian W, Duan W, Lei J, Ma J, Ma Q, Han L
Molecular oncology13(2)228-245(2019 02)

Plasmodium falciparum infected erythrocytes can bind to host receptors integrins αVβ3 and αVβ6 through DBLδ1_D4 domain of PFL2665c PfEMP1 protein.
Chesnokov O, Merritt J, Tcherniuk SO, Milman N, Oleinikov AV
Scientific reports8(1)17871(2018 12)

Inhibition of skin carcinogenesis by suppression of NF-κB dependent ITGAV and TIMP-1 expression in IL-32γ overexpressed condition.
Lee YS, Lee CH, Bae JT, Nam KT, Moon DB, Hwang OK, Choi JS, Kim TH, Jun HO, Jung YS, Hwang DY, Han SB, Yoon DY, Hong JT
Journal of experimental & clinical cancer research : CR37(1)293(2018 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ITGAV gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITGAV cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23663	NM_002210.4 Latest version!	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu107399	NM_002210.5 Latest version!	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu108212	NM_001145000.3 Latest version!	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu23508	NM_001144999.2 Latest version!	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu27622	NM_001145000.2 Latest version!	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITGAV ( NM_002210.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002201.1 Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23663
Clone ID Related Accession (Same CDS sequence)	NM_002210.4
Accession Version	NM_002210.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3147bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512403200000
Organism	Homo sapiens(human)
Product	integrin alpha-V isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309711.1, BC136442.1, DA736912.1, CB962576.1, CN409399.1, BC047454.1 and BQ101180.1. On May 10, 2013 this sequence version replaced NM_002210.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACAAGATAT TGATGCTGAT 
GGACAGGGAT TTTGTCAAGG AGGATTCAGC ATTGATTTTA CTAAAGCTGA CAGAGTACTT 
CTTGGTGGTC CTGGTAGCTT TTATTGGCAA GGTCAGCTTA TTTCGGATCA AGTGGCAGAA 
ATCGTATCTA AATACGACCC CAATGTTTAC AGCATCAAGT ATAATAACCA ATTAGCAACT 
CGGACTGCAC AAGCTATTTT TGATGACAGC TATTTGGGTT ATTCTGTGGC TGTCGGAGAT 
TTCAATGGTG ATGGCATAGA TGACTTTGTT TCAGGAGTTC CAAGAGCAGC AAGGACTTTG 
GGAATGGTTT ATATTTATGA TGGGAAGAAC ATGTCCTCCT TATACAATTT TACTGGCGAG 
CAGATGGCTG CATATTTCGG ATTTTCTGTA GCTGCCACTG ACATTAATGG AGATGATTAT 
GCAGATGTGT TTATTGGAGC ACCTCTCTTC ATGGATCGTG GCTCTGATGG CAAACTCCAA 
GAGGTGGGGC AGGTCTCAGT GTCTCTACAG AGAGCTTCAG GAGACTTCCA GACGACAAAG 
CTGAATGGAT TTGAGGTCTT TGCACGGTTT GGCAGTGCCA TAGCTCCTTT GGGAGATCTG 
GACCAGGATG GTTTCAATGA TATTGCAATT GCTGCTCCAT ATGGGGGTGA AGATAAAAAA 
GGAATTGTTT ATATCTTCAA TGGAAGATCA ACAGGCTTGA ACGCAGTCCC ATCTCAAATC 
CTTGAAGGGC AGTGGGCTGC TCGAAGCATG CCACCAAGCT TTGGCTATTC AATGAAAGGA 
GCCACAGATA TAGACAAAAA TGGATATCCA GACTTAATTG TAGGAGCTTT TGGTGTAGAT 
CGAGCTATCT TATACAGGGC CAGACCAGTT ATCACTGTAA ATGCTGGTCT TGAAGTGTAC 
CCTAGCATTT TAAATCAAGA CAATAAAACC TGCTCACTGC CTGGAACAGC TCTCAAAGTT 
TCCTGTTTTA ATGTTAGGTT CTGCTTAAAG GCAGATGGCA AAGGAGTACT TCCCAGGAAA 
CTTAATTTCC AGGTGGAACT TCTTTTGGAT AAACTCAAGC AAAAGGGAGC AATTCGACGA 
GCACTGTTTC TCTACAGCAG GTCCCCAAGT CACTCCAAGA ACATGACTAT TTCAAGGGGG 
GGACTGATGC AGTGTGAGGA ATTGATAGCG TATCTGCGGG ATGAATCTGA ATTTAGAGAC 
AAACTCACTC CAATTACTAT TTTTATGGAA TATCGGTTGG ATTATAGAAC AGCTGCTGAT 
ACAACAGGCT TGCAACCCAT TCTTAACCAG TTCACGCCTG CTAACATTAG TCGACAGGCT 
CACATTCTAC TTGACTGTGG TGAAGACAAT GTCTGTAAAC CCAAGCTGGA AGTTTCTGTA 
GATAGTGATC AAAAGAAGAT CTATATTGGG GATGACAACC CTCTGACATT GATTGTTAAG 
GCTCAGAATC AAGGAGAAGG TGCCTACGAA GCTGAGCTCA TCGTTTCCAT TCCACTGCAG 
GCTGATTTCA TCGGGGTTGT CCGAAACAAT GAAGCCTTAG CAAGACTTTC CTGTGCATTT 
AAGACAGAAA ACCAAACTCG CCAGGTGGTA TGTGACCTTG GAAACCCAAT GAAGGCTGGA 
ACTCAACTCT TAGCTGGTCT TCGTTTCAGT GTGCACCAGC AGTCAGAGAT GGATACTTCT 
GTGAAATTTG ACTTACAAAT CCAAAGCTCA AATCTATTTG ACAAAGTAAG CCCAGTTGTA 
TCTCACAAAG TTGATCTTGC TGTTTTAGCT GCAGTTGAGA TAAGAGGAGT CTCGAGTCCT 
GATCATATCT TTCTTCCGAT TCCAAACTGG GAGCACAAGG AGAACCCTGA GACTGAAGAA 
GATGTTGGGC CAGTTGTTCA GCACATCTAT GAGCTGAGAA ACAATGGTCC AAGTTCATTC 
AGCAAGGCAA TGCTCCATCT TCAGTGGCCT TACAAATATA ATAATAACAC TCTGTTGTAT 
ATCCTTCATT ATGATATTGA TGGACCAATG AACTGCACTT CAGATATGGA GATCAACCCT 
TTGAGAATTA AGATCTCATC TTTGCAAACA ACTGAAAAGA ATGACACGGT TGCCGGGCAA 
GGTGAGCGGG ACCATCTCAT CACTAAGCGG GATCTTGCCC TCAGTGAAGG AGATATTCAC 
ACTTTGGGTT GTGGAGTTGC TCAGTGCTTG AAGATTGTCT GCCAAGTTGG GAGATTAGAC 
AGAGGAAAGA GTGCAATCTT GTACGTAAAG TCATTACTGT GGACTGAGAC TTTTATGAAT 
AAAGAAAATC AGAATCATTC CTATTCTCTG AAGTCGTCTG CTTCATTTAA TGTCATAGAG 
TTTCCTTATA AGAATCTTCC AATTGAGGAT ATCACCAACT CCACATTGGT TACCACTAAT 
GTCACCTGGG GCATTCAGCC AGCGCCCATG CCTGTGCCTG TGTGGGTGAT CATTTTAGCA 
GTTCTAGCAG GATTGTTGCT ACTGGCTGTT TTGGTATTTG TAATGTACAG GATGGGCTTT 
TTTAAACGGG TCCGGCCACC TCAAGAAGAA CAAGAAAGGG AGCAGCTTCA ACCTCATGAA 
AATGGTGAAG GAAACTCAGA AACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002201.1
CDS	277..3423
Translation	MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	NM_002210.4
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002210.4

ORF Insert Sequence:

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACAAGATAT TGATGCTGAT 
GGACAGGGAT TTTGTCAAGG AGGATTCAGC ATTGATTTTA CTAAAGCTGA CAGAGTACTT 
CTTGGTGGTC CTGGTAGCTT TTATTGGCAA GGTCAGCTTA TTTCGGATCA AGTGGCAGAA 
ATCGTATCTA AATACGACCC CAATGTTTAC AGCATCAAGT ATAATAACCA ATTAGCAACT 
CGGACTGCAC AAGCTATTTT TGATGACAGC TATTTGGGTT ATTCTGTGGC TGTCGGAGAT 
TTCAATGGTG ATGGCATAGA TGACTTTGTT TCAGGAGTTC CAAGAGCAGC AAGGACTTTG 
GGAATGGTTT ATATTTATGA TGGGAAGAAC ATGTCCTCCT TATACAATTT TACTGGCGAG 
CAGATGGCTG CATATTTCGG ATTTTCTGTA GCTGCCACTG ACATTAATGG AGATGATTAT 
GCAGATGTGT TTATTGGAGC ACCTCTCTTC ATGGATCGTG GCTCTGATGG CAAACTCCAA 
GAGGTGGGGC AGGTCTCAGT GTCTCTACAG AGAGCTTCAG GAGACTTCCA GACGACAAAG 
CTGAATGGAT TTGAGGTCTT TGCACGGTTT GGCAGTGCCA TAGCTCCTTT GGGAGATCTG 
GACCAGGATG GTTTCAATGA TATTGCAATT GCTGCTCCAT ATGGGGGTGA AGATAAAAAA 
GGAATTGTTT ATATCTTCAA TGGAAGATCA ACAGGCTTGA ACGCAGTCCC ATCTCAAATC 
CTTGAAGGGC AGTGGGCTGC TCGAAGCATG CCACCAAGCT TTGGCTATTC AATGAAAGGA 
GCCACAGATA TAGACAAAAA TGGATATCCA GACTTAATTG TAGGAGCTTT TGGTGTAGAT 
CGAGCTATCT TATACAGGGC CAGACCAGTT ATCACTGTAA ATGCTGGTCT TGAAGTGTAC 
CCTAGCATTT TAAATCAAGA CAATAAAACC TGCTCACTGC CTGGAACAGC TCTCAAAGTT 
TCCTGTTTTA ATGTTAGGTT CTGCTTAAAG GCAGATGGCA AAGGAGTACT TCCCAGGAAA 
CTTAATTTCC AGGTGGAACT TCTTTTGGAT AAACTCAAGC AAAAGGGAGC AATTCGACGA 
GCACTGTTTC TCTACAGCAG GTCCCCAAGT CACTCCAAGA ACATGACTAT TTCAAGGGGG 
GGACTGATGC AGTGTGAGGA ATTGATAGCG TATCTGCGGG ATGAATCTGA ATTTAGAGAC 
AAACTCACTC CAATTACTAT TTTTATGGAA TATCGGTTGG ATTATAGAAC AGCTGCTGAT 
ACAACAGGCT TGCAACCCAT TCTTAACCAG TTCACGCCTG CTAACATTAG TCGACAGGCT 
CACATTCTAC TTGACTGTGG TGAAGACAAT GTCTGTAAAC CCAAGCTGGA AGTTTCTGTA 
GATAGTGATC AAAAGAAGAT CTATATTGGG GATGACAACC CTCTGACATT GATTGTTAAG 
GCTCAGAATC AAGGAGAAGG TGCCTACGAA GCTGAGCTCA TCGTTTCCAT TCCACTGCAG 
GCTGATTTCA TCGGGGTTGT CCGAAACAAT GAAGCCTTAG CAAGACTTTC CTGTGCATTT 
AAGACAGAAA ACCAAACTCG CCAGGTGGTA TGTGACCTTG GAAACCCAAT GAAGGCTGGA 
ACTCAACTCT TAGCTGGTCT TCGTTTCAGT GTGCACCAGC AGTCAGAGAT GGATACTTCT 
GTGAAATTTG ACTTACAAAT CCAAAGCTCA AATCTATTTG ACAAAGTAAG CCCAGTTGTA 
TCTCACAAAG TTGATCTTGC TGTTTTAGCT GCAGTTGAGA TAAGAGGAGT CTCGAGTCCT 
GATCATATCT TTCTTCCGAT TCCAAACTGG GAGCACAAGG AGAACCCTGA GACTGAAGAA 
GATGTTGGGC CAGTTGTTCA GCACATCTAT GAGCTGAGAA ACAATGGTCC AAGTTCATTC 
AGCAAGGCAA TGCTCCATCT TCAGTGGCCT TACAAATATA ATAATAACAC TCTGTTGTAT 
ATCCTTCATT ATGATATTGA TGGACCAATG AACTGCACTT CAGATATGGA GATCAACCCT 
TTGAGAATTA AGATCTCATC TTTGCAAACA ACTGAAAAGA ATGACACGGT TGCCGGGCAA 
GGTGAGCGGG ACCATCTCAT CACTAAGCGG GATCTTGCCC TCAGTGAAGG AGATATTCAC 
ACTTTGGGTT GTGGAGTTGC TCAGTGCTTG AAGATTGTCT GCCAAGTTGG GAGATTAGAC 
AGAGGAAAGA GTGCAATCTT GTACGTAAAG TCATTACTGT GGACTGAGAC TTTTATGAAT 
AAAGAAAATC AGAATCATTC CTATTCTCTG AAGTCGTCTG CTTCATTTAA TGTCATAGAG 
TTTCCTTATA AGAATCTTCC AATTGAGGAT ATCACCAACT CCACATTGGT TACCACTAAT 
GTCACCTGGG GCATTCAGCC AGCGCCCATG CCTGTGCCTG TGTGGGTGAT CATTTTAGCA 
GTTCTAGCAG GATTGTTGCT ACTGGCTGTT TTGGTATTTG TAATGTACAG GATGGGCTTT 
TTTAAACGGG TCCGGCCACC TCAAGAAGAA CAAGAAAGGG AGCAGCTTCA ACCTCATGAA 
AATGGTGAAG GAAACTCAGA AACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGAV ( NM_002210.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002201.2 Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu107399
Clone ID Related Accession (Same CDS sequence)	NM_002210.5
Accession Version	NM_002210.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3147bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Homo sapiens(human)
Product	integrin alpha-V isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC017101.10. On Nov 22, 2018 this sequence version replaced NM_002210.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.70334.1, SRR1660803.188516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261023.8/ ENSP00000261023.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACAAGATAT TGATGCTGAT 
GGACAGGGAT TTTGTCAAGG AGGATTCAGC ATTGATTTTA CTAAAGCTGA CAGAGTACTT 
CTTGGTGGTC CTGGTAGCTT TTATTGGCAA GGTCAGCTTA TTTCGGATCA AGTGGCAGAA 
ATCGTATCTA AATACGACCC CAATGTTTAC AGCATCAAGT ATAATAACCA ATTAGCAACT 
CGGACTGCAC AAGCTATTTT TGATGACAGC TATTTGGGTT ATTCTGTGGC TGTCGGAGAT 
TTCAATGGTG ATGGCATAGA TGACTTTGTT TCAGGAGTTC CAAGAGCAGC AAGGACTTTG 
GGAATGGTTT ATATTTATGA TGGGAAGAAC ATGTCCTCCT TATACAATTT TACTGGCGAG 
CAGATGGCTG CATATTTCGG ATTTTCTGTA GCTGCCACTG ACATTAATGG AGATGATTAT 
GCAGATGTGT TTATTGGAGC ACCTCTCTTC ATGGATCGTG GCTCTGATGG CAAACTCCAA 
GAGGTGGGGC AGGTCTCAGT GTCTCTACAG AGAGCTTCAG GAGACTTCCA GACGACAAAG 
CTGAATGGAT TTGAGGTCTT TGCACGGTTT GGCAGTGCCA TAGCTCCTTT GGGAGATCTG 
GACCAGGATG GTTTCAATGA TATTGCAATT GCTGCTCCAT ATGGGGGTGA AGATAAAAAA 
GGAATTGTTT ATATCTTCAA TGGAAGATCA ACAGGCTTGA ACGCAGTCCC ATCTCAAATC 
CTTGAAGGGC AGTGGGCTGC TCGAAGCATG CCACCAAGCT TTGGCTATTC AATGAAAGGA 
GCCACAGATA TAGACAAAAA TGGATATCCA GACTTAATTG TAGGAGCTTT TGGTGTAGAT 
CGAGCTATCT TATACAGGGC CAGACCAGTT ATCACTGTAA ATGCTGGTCT TGAAGTGTAC 
CCTAGCATTT TAAATCAAGA CAATAAAACC TGCTCACTGC CTGGAACAGC TCTCAAAGTT 
TCCTGTTTTA ATGTTAGGTT CTGCTTAAAG GCAGATGGCA AAGGAGTACT TCCCAGGAAA 
CTTAATTTCC AGGTGGAACT TCTTTTGGAT AAACTCAAGC AAAAGGGAGC AATTCGACGA 
GCACTGTTTC TCTACAGCAG GTCCCCAAGT CACTCCAAGA ACATGACTAT TTCAAGGGGG 
GGACTGATGC AGTGTGAGGA ATTGATAGCG TATCTGCGGG ATGAATCTGA ATTTAGAGAC 
AAACTCACTC CAATTACTAT TTTTATGGAA TATCGGTTGG ATTATAGAAC AGCTGCTGAT 
ACAACAGGCT TGCAACCCAT TCTTAACCAG TTCACGCCTG CTAACATTAG TCGACAGGCT 
CACATTCTAC TTGACTGTGG TGAAGACAAT GTCTGTAAAC CCAAGCTGGA AGTTTCTGTA 
GATAGTGATC AAAAGAAGAT CTATATTGGG GATGACAACC CTCTGACATT GATTGTTAAG 
GCTCAGAATC AAGGAGAAGG TGCCTACGAA GCTGAGCTCA TCGTTTCCAT TCCACTGCAG 
GCTGATTTCA TCGGGGTTGT CCGAAACAAT GAAGCCTTAG CAAGACTTTC CTGTGCATTT 
AAGACAGAAA ACCAAACTCG CCAGGTGGTA TGTGACCTTG GAAACCCAAT GAAGGCTGGA 
ACTCAACTCT TAGCTGGTCT TCGTTTCAGT GTGCACCAGC AGTCAGAGAT GGATACTTCT 
GTGAAATTTG ACTTACAAAT CCAAAGCTCA AATCTATTTG ACAAAGTAAG CCCAGTTGTA 
TCTCACAAAG TTGATCTTGC TGTTTTAGCT GCAGTTGAGA TAAGAGGAGT CTCGAGTCCT 
GATCATGTCT TTCTTCCGAT TCCAAACTGG GAGCACAAGG AGAACCCTGA GACTGAAGAA 
GATGTTGGGC CAGTTGTTCA GCACATCTAT GAGCTGAGAA ACAATGGTCC AAGTTCATTC 
AGCAAGGCAA TGCTCCATCT TCAGTGGCCT TACAAATATA ATAATAACAC TCTGTTGTAT 
ATCCTTCATT ATGATATTGA TGGACCAATG AACTGCACTT CAGATATGGA GATCAACCCT 
TTGAGAATTA AGATCTCATC TTTGCAAACA ACTGAAAAGA ATGACACGGT TGCCGGGCAA 
GGTGAGCGGG ACCATCTCAT CACTAAGCGG GATCTTGCCC TCAGTGAAGG AGATATTCAC 
ACTTTGGGTT GTGGAGTTGC TCAGTGCTTG AAGATTGTCT GCCAAGTTGG GAGATTAGAC 
AGAGGAAAGA GTGCAATCTT GTACGTAAAG TCATTACTGT GGACTGAGAC TTTTATGAAT 
AAAGAAAATC AGAATCATTC CTATTCTCTG AAGTCGTCTG CTTCATTTAA TGTCATAGAG 
TTTCCTTATA AGAATCTTCC AATTGAGGAT ATCACCAACT CCACATTGGT TACCACTAAT 
GTCACCTGGG GCATTCAGCC AGCGCCCATG CCTGTGCCTG TGTGGGTGAT CATTTTAGCA 
GTTCTAGCAG GATTGTTGCT ACTGGCTGTT TTGGTATTTG TAATGTACAG GATGGGCTTT 
TTTAAACGGG TCCGGCCACC TCAAGAAGAA CAAGAAAGGG AGCAGCTTCA ACCTCATGAA 
AATGGTGAAG GAAACTCAGA AACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002201.2
CDS	284..3430
Translation	MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	NM_002210.5
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002210.5

ORF Insert Sequence:

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACAAGATAT TGATGCTGAT 
GGACAGGGAT TTTGTCAAGG AGGATTCAGC ATTGATTTTA CTAAAGCTGA CAGAGTACTT 
CTTGGTGGTC CTGGTAGCTT TTATTGGCAA GGTCAGCTTA TTTCGGATCA AGTGGCAGAA 
ATCGTATCTA AATACGACCC CAATGTTTAC AGCATCAAGT ATAATAACCA ATTAGCAACT 
CGGACTGCAC AAGCTATTTT TGATGACAGC TATTTGGGTT ATTCTGTGGC TGTCGGAGAT 
TTCAATGGTG ATGGCATAGA TGACTTTGTT TCAGGAGTTC CAAGAGCAGC AAGGACTTTG 
GGAATGGTTT ATATTTATGA TGGGAAGAAC ATGTCCTCCT TATACAATTT TACTGGCGAG 
CAGATGGCTG CATATTTCGG ATTTTCTGTA GCTGCCACTG ACATTAATGG AGATGATTAT 
GCAGATGTGT TTATTGGAGC ACCTCTCTTC ATGGATCGTG GCTCTGATGG CAAACTCCAA 
GAGGTGGGGC AGGTCTCAGT GTCTCTACAG AGAGCTTCAG GAGACTTCCA GACGACAAAG 
CTGAATGGAT TTGAGGTCTT TGCACGGTTT GGCAGTGCCA TAGCTCCTTT GGGAGATCTG 
GACCAGGATG GTTTCAATGA TATTGCAATT GCTGCTCCAT ATGGGGGTGA AGATAAAAAA 
GGAATTGTTT ATATCTTCAA TGGAAGATCA ACAGGCTTGA ACGCAGTCCC ATCTCAAATC 
CTTGAAGGGC AGTGGGCTGC TCGAAGCATG CCACCAAGCT TTGGCTATTC AATGAAAGGA 
GCCACAGATA TAGACAAAAA TGGATATCCA GACTTAATTG TAGGAGCTTT TGGTGTAGAT 
CGAGCTATCT TATACAGGGC CAGACCAGTT ATCACTGTAA ATGCTGGTCT TGAAGTGTAC 
CCTAGCATTT TAAATCAAGA CAATAAAACC TGCTCACTGC CTGGAACAGC TCTCAAAGTT 
TCCTGTTTTA ATGTTAGGTT CTGCTTAAAG GCAGATGGCA AAGGAGTACT TCCCAGGAAA 
CTTAATTTCC AGGTGGAACT TCTTTTGGAT AAACTCAAGC AAAAGGGAGC AATTCGACGA 
GCACTGTTTC TCTACAGCAG GTCCCCAAGT CACTCCAAGA ACATGACTAT TTCAAGGGGG 
GGACTGATGC AGTGTGAGGA ATTGATAGCG TATCTGCGGG ATGAATCTGA ATTTAGAGAC 
AAACTCACTC CAATTACTAT TTTTATGGAA TATCGGTTGG ATTATAGAAC AGCTGCTGAT 
ACAACAGGCT TGCAACCCAT TCTTAACCAG TTCACGCCTG CTAACATTAG TCGACAGGCT 
CACATTCTAC TTGACTGTGG TGAAGACAAT GTCTGTAAAC CCAAGCTGGA AGTTTCTGTA 
GATAGTGATC AAAAGAAGAT CTATATTGGG GATGACAACC CTCTGACATT GATTGTTAAG 
GCTCAGAATC AAGGAGAAGG TGCCTACGAA GCTGAGCTCA TCGTTTCCAT TCCACTGCAG 
GCTGATTTCA TCGGGGTTGT CCGAAACAAT GAAGCCTTAG CAAGACTTTC CTGTGCATTT 
AAGACAGAAA ACCAAACTCG CCAGGTGGTA TGTGACCTTG GAAACCCAAT GAAGGCTGGA 
ACTCAACTCT TAGCTGGTCT TCGTTTCAGT GTGCACCAGC AGTCAGAGAT GGATACTTCT 
GTGAAATTTG ACTTACAAAT CCAAAGCTCA AATCTATTTG ACAAAGTAAG CCCAGTTGTA 
TCTCACAAAG TTGATCTTGC TGTTTTAGCT GCAGTTGAGA TAAGAGGAGT CTCGAGTCCT 
GATCATGTCT TTCTTCCGAT TCCAAACTGG GAGCACAAGG AGAACCCTGA GACTGAAGAA 
GATGTTGGGC CAGTTGTTCA GCACATCTAT GAGCTGAGAA ACAATGGTCC AAGTTCATTC 
AGCAAGGCAA TGCTCCATCT TCAGTGGCCT TACAAATATA ATAATAACAC TCTGTTGTAT 
ATCCTTCATT ATGATATTGA TGGACCAATG AACTGCACTT CAGATATGGA GATCAACCCT 
TTGAGAATTA AGATCTCATC TTTGCAAACA ACTGAAAAGA ATGACACGGT TGCCGGGCAA 
GGTGAGCGGG ACCATCTCAT CACTAAGCGG GATCTTGCCC TCAGTGAAGG AGATATTCAC 
ACTTTGGGTT GTGGAGTTGC TCAGTGCTTG AAGATTGTCT GCCAAGTTGG GAGATTAGAC 
AGAGGAAAGA GTGCAATCTT GTACGTAAAG TCATTACTGT GGACTGAGAC TTTTATGAAT 
AAAGAAAATC AGAATCATTC CTATTCTCTG AAGTCGTCTG CTTCATTTAA TGTCATAGAG 
TTTCCTTATA AGAATCTTCC AATTGAGGAT ATCACCAACT CCACATTGGT TACCACTAAT 
GTCACCTGGG GCATTCAGCC AGCGCCCATG CCTGTGCCTG TGTGGGTGAT CATTTTAGCA 
GTTCTAGCAG GATTGTTGCT ACTGGCTGTT TTGGTATTTG TAATGTACAG GATGGGCTTT 
TTTAAACGGG TCCGGCCACC TCAAGAAGAA CAAGAAAGGG AGCAGCTTCA ACCTCATGAA 
AATGGTGAAG GAAACTCAGA AACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGAV ( NM_001145000.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138472.2 Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu108212
Clone ID Related Accession (Same CDS sequence)	NM_001145000.3
Accession Version	NM_001145000.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3039bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577980800000
Organism	Homo sapiens(human)
Product	integrin alpha-V isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC017101.10. On May 31, 2019 this sequence version replaced NM_001145000.2. Transcript Variant: This variant (3) lacks two alternate in-frame exons in the coding region compared to variant 1. This results in a shorter protein (isoform 3) compared to isoform 1. It is not known whether this isoform (3) is proteolytically processed in the same manner as isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.12945.1, AB209894.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACGTCAGCT TATTTCGGAT 
CAAGTGGCAG AAATCGTATC TAAATACGAC CCCAATGTTT ACAGCATCAA GTATAATAAC 
CAATTAGCAA CTCGGACTGC ACAAGCTATT TTTGATGACA GCTATTTGGG TTATTCTGTG 
GCTGTCGGAG ATTTCAATGG TGATGGCATA GATGACTTTG TTTCAGGAGT TCCAAGAGCA 
GCAAGGACTT TGGGAATGGT TTATATTTAT GATGGGAAGA ACATGTCCTC CTTATACAAT 
TTTACTGGCG AGCAGATGGC TGCATATTTC GGATTTTCTG TAGCTGCCAC TGACATTAAT 
GGAGATGATT ATGCAGATGT GTTTATTGGA GCACCTCTCT TCATGGATCG TGGCTCTGAT 
GGCAAACTCC AAGAGGTGGG GCAGGTCTCA GTGTCTCTAC AGAGAGCTTC AGGAGACTTC 
CAGACGACAA AGCTGAATGG ATTTGAGGTC TTTGCACGGT TTGGCAGTGC CATAGCTCCT 
TTGGGAGATC TGGACCAGGA TGGTTTCAAT GATATTGCAA TTGCTGCTCC ATATGGGGGT 
GAAGATAAAA AAGGAATTGT TTATATCTTC AATGGAAGAT CAACAGGCTT GAACGCAGTC 
CCATCTCAAA TCCTTGAAGG GCAGTGGGCT GCTCGAAGCA TGCCACCAAG CTTTGGCTAT 
TCAATGAAAG GAGCCACAGA TATAGACAAA AATGGATATC CAGACTTAAT TGTAGGAGCT 
TTTGGTGTAG ATCGAGCTAT CTTATACAGG GCCAGACCAG TTATCACTGT AAATGCTGGT 
CTTGAAGTGT ACCCTAGCAT TTTAAATCAA GACAATAAAA CCTGCTCACT GCCTGGAACA 
GCTCTCAAAG TTTCCTGTTT TAATGTTAGG TTCTGCTTAA AGGCAGATGG CAAAGGAGTA 
CTTCCCAGGA AACTTAATTT CCAGGTGGAA CTTCTTTTGG ATAAACTCAA GCAAAAGGGA 
GCAATTCGAC GAGCACTGTT TCTCTACAGC AGGTCCCCAA GTCACTCCAA GAACATGACT 
ATTTCAAGGG GGGGACTGAT GCAGTGTGAG GAATTGATAG CGTATCTGCG GGATGAATCT 
GAATTTAGAG ACAAACTCAC TCCAATTACT ATTTTTATGG AATATCGGTT GGATTATAGA 
ACAGCTGCTG ATACAACAGG CTTGCAACCC ATTCTTAACC AGTTCACGCC TGCTAACATT 
AGTCGACAGG CTCACATTCT ACTTGACTGT GGTGAAGACA ATGTCTGTAA ACCCAAGCTG 
GAAGTTTCTG TAGATAGTGA TCAAAAGAAG ATCTATATTG GGGATGACAA CCCTCTGACA 
TTGATTGTTA AGGCTCAGAA TCAAGGAGAA GGTGCCTACG AAGCTGAGCT CATCGTTTCC 
ATTCCACTGC AGGCTGATTT CATCGGGGTT GTCCGAAACA ATGAAGCCTT AGCAAGACTT 
TCCTGTGCAT TTAAGACAGA AAACCAAACT CGCCAGGTGG TATGTGACCT TGGAAACCCA 
ATGAAGGCTG GAACTCAACT CTTAGCTGGT CTTCGTTTCA GTGTGCACCA GCAGTCAGAG 
ATGGATACTT CTGTGAAATT TGACTTACAA ATCCAAAGCT CAAATCTATT TGACAAAGTA 
AGCCCAGTTG TATCTCACAA AGTTGATCTT GCTGTTTTAG CTGCAGTTGA GATAAGAGGA 
GTCTCGAGTC CTGATCATGT CTTTCTTCCG ATTCCAAACT GGGAGCACAA GGAGAACCCT 
GAGACTGAAG AAGATGTTGG GCCAGTTGTT CAGCACATCT ATGAGCTGAG AAACAATGGT 
CCAAGTTCAT TCAGCAAGGC AATGCTCCAT CTTCAGTGGC CTTACAAATA TAATAATAAC 
ACTCTGTTGT ATATCCTTCA TTATGATATT GATGGACCAA TGAACTGCAC TTCAGATATG 
GAGATCAACC CTTTGAGAAT TAAGATCTCA TCTTTGCAAA CAACTGAAAA GAATGACACG 
GTTGCCGGGC AAGGTGAGCG GGACCATCTC ATCACTAAGC GGGATCTTGC CCTCAGTGAA 
GGAGATATTC ACACTTTGGG TTGTGGAGTT GCTCAGTGCT TGAAGATTGT CTGCCAAGTT 
GGGAGATTAG ACAGAGGAAA GAGTGCAATC TTGTACGTAA AGTCATTACT GTGGACTGAG 
ACTTTTATGA ATAAAGAAAA TCAGAATCAT TCCTATTCTC TGAAGTCGTC TGCTTCATTT 
AATGTCATAG AGTTTCCTTA TAAGAATCTT CCAATTGAGG ATATCACCAA CTCCACATTG 
GTTACCACTA ATGTCACCTG GGGCATTCAG CCAGCGCCCA TGCCTGTGCC TGTGTGGGTG 
ATCATTTTAG CAGTTCTAGC AGGATTGTTG CTACTGGCTG TTTTGGTATT TGTAATGTAC 
AGGATGGGCT TTTTTAAACG GGTCCGGCCA CCTCAAGAAG AACAAGAAAG GGAGCAGCTT 
CAACCTCATG AAAATGGTGA AGGAAACTCA GAAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138472.2
CDS	284..3322
Translation	MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	NM_001145000.3
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145000.3

ORF Insert Sequence:

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACGTCAGCT TATTTCGGAT 
CAAGTGGCAG AAATCGTATC TAAATACGAC CCCAATGTTT ACAGCATCAA GTATAATAAC 
CAATTAGCAA CTCGGACTGC ACAAGCTATT TTTGATGACA GCTATTTGGG TTATTCTGTG 
GCTGTCGGAG ATTTCAATGG TGATGGCATA GATGACTTTG TTTCAGGAGT TCCAAGAGCA 
GCAAGGACTT TGGGAATGGT TTATATTTAT GATGGGAAGA ACATGTCCTC CTTATACAAT 
TTTACTGGCG AGCAGATGGC TGCATATTTC GGATTTTCTG TAGCTGCCAC TGACATTAAT 
GGAGATGATT ATGCAGATGT GTTTATTGGA GCACCTCTCT TCATGGATCG TGGCTCTGAT 
GGCAAACTCC AAGAGGTGGG GCAGGTCTCA GTGTCTCTAC AGAGAGCTTC AGGAGACTTC 
CAGACGACAA AGCTGAATGG ATTTGAGGTC TTTGCACGGT TTGGCAGTGC CATAGCTCCT 
TTGGGAGATC TGGACCAGGA TGGTTTCAAT GATATTGCAA TTGCTGCTCC ATATGGGGGT 
GAAGATAAAA AAGGAATTGT TTATATCTTC AATGGAAGAT CAACAGGCTT GAACGCAGTC 
CCATCTCAAA TCCTTGAAGG GCAGTGGGCT GCTCGAAGCA TGCCACCAAG CTTTGGCTAT 
TCAATGAAAG GAGCCACAGA TATAGACAAA AATGGATATC CAGACTTAAT TGTAGGAGCT 
TTTGGTGTAG ATCGAGCTAT CTTATACAGG GCCAGACCAG TTATCACTGT AAATGCTGGT 
CTTGAAGTGT ACCCTAGCAT TTTAAATCAA GACAATAAAA CCTGCTCACT GCCTGGAACA 
GCTCTCAAAG TTTCCTGTTT TAATGTTAGG TTCTGCTTAA AGGCAGATGG CAAAGGAGTA 
CTTCCCAGGA AACTTAATTT CCAGGTGGAA CTTCTTTTGG ATAAACTCAA GCAAAAGGGA 
GCAATTCGAC GAGCACTGTT TCTCTACAGC AGGTCCCCAA GTCACTCCAA GAACATGACT 
ATTTCAAGGG GGGGACTGAT GCAGTGTGAG GAATTGATAG CGTATCTGCG GGATGAATCT 
GAATTTAGAG ACAAACTCAC TCCAATTACT ATTTTTATGG AATATCGGTT GGATTATAGA 
ACAGCTGCTG ATACAACAGG CTTGCAACCC ATTCTTAACC AGTTCACGCC TGCTAACATT 
AGTCGACAGG CTCACATTCT ACTTGACTGT GGTGAAGACA ATGTCTGTAA ACCCAAGCTG 
GAAGTTTCTG TAGATAGTGA TCAAAAGAAG ATCTATATTG GGGATGACAA CCCTCTGACA 
TTGATTGTTA AGGCTCAGAA TCAAGGAGAA GGTGCCTACG AAGCTGAGCT CATCGTTTCC 
ATTCCACTGC AGGCTGATTT CATCGGGGTT GTCCGAAACA ATGAAGCCTT AGCAAGACTT 
TCCTGTGCAT TTAAGACAGA AAACCAAACT CGCCAGGTGG TATGTGACCT TGGAAACCCA 
ATGAAGGCTG GAACTCAACT CTTAGCTGGT CTTCGTTTCA GTGTGCACCA GCAGTCAGAG 
ATGGATACTT CTGTGAAATT TGACTTACAA ATCCAAAGCT CAAATCTATT TGACAAAGTA 
AGCCCAGTTG TATCTCACAA AGTTGATCTT GCTGTTTTAG CTGCAGTTGA GATAAGAGGA 
GTCTCGAGTC CTGATCATGT CTTTCTTCCG ATTCCAAACT GGGAGCACAA GGAGAACCCT 
GAGACTGAAG AAGATGTTGG GCCAGTTGTT CAGCACATCT ATGAGCTGAG AAACAATGGT 
CCAAGTTCAT TCAGCAAGGC AATGCTCCAT CTTCAGTGGC CTTACAAATA TAATAATAAC 
ACTCTGTTGT ATATCCTTCA TTATGATATT GATGGACCAA TGAACTGCAC TTCAGATATG 
GAGATCAACC CTTTGAGAAT TAAGATCTCA TCTTTGCAAA CAACTGAAAA GAATGACACG 
GTTGCCGGGC AAGGTGAGCG GGACCATCTC ATCACTAAGC GGGATCTTGC CCTCAGTGAA 
GGAGATATTC ACACTTTGGG TTGTGGAGTT GCTCAGTGCT TGAAGATTGT CTGCCAAGTT 
GGGAGATTAG ACAGAGGAAA GAGTGCAATC TTGTACGTAA AGTCATTACT GTGGACTGAG 
ACTTTTATGA ATAAAGAAAA TCAGAATCAT TCCTATTCTC TGAAGTCGTC TGCTTCATTT 
AATGTCATAG AGTTTCCTTA TAAGAATCTT CCAATTGAGG ATATCACCAA CTCCACATTG 
GTTACCACTA ATGTCACCTG GGGCATTCAG CCAGCGCCCA TGCCTGTGCC TGTGTGGGTG 
ATCATTTTAG CAGTTCTAGC AGGATTGTTG CTACTGGCTG TTTTGGTATT TGTAATGTAC 
AGGATGGGCT TTTTTAAACG GGTCCGGCCA CCTCAAGAAG AACAAGAAAG GGAGCAGCTT 
CAACCTCATG AAAATGGTGA AGGAAACTCA GAAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGAV ( NM_001144999.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138471.1 Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23508
Clone ID Related Accession (Same CDS sequence)	NM_001144999.2
Accession Version	NM_001144999.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3009bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Homo sapiens(human)
Product	integrin alpha-V isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302990.1, BC047454.1, DA736912.1, CB962576.1, CN409399.1 and BQ101180.1. On May 10, 2013 this sequence version replaced NM_001144999.1. Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct and shorter N-terminus, compared to isoform 1. It is not known whether this isoform (2) is proteolytically processed in the same manner as isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302990.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCTAG GCACCCTCCT TCTGATCCTG TACATCTTAA TGTTGTGCCG GATGTTTCTT 
CTCGTGGGAG CTCCCAAAGC AAACACCACC CAGCCTGGGA TTGTGGAAGG AGGGCAGGTC 
CTCAAATGTG ACTGGTCTTC TACCCGCCGG TGCCAGCCAA TTGAATTTGA TGCAACAGGC 
AATAGAGATT ATGCCAAGGA TGATCCATTG GAATTTAAGT CCCATCAGTG GTTTGGAGCA 
TCTGTGAGGT CGAAACAGGA TAAAATTTTG GCCTGTGCCC CATTGTACCA TTGGAGAACT 
GAGATGAAAC AGGAGCGAGA GCCTGTTGGA ACATGCTTTC TTCAAGATGG AACAAAGACT 
GTTGAGTATG CTCCATGTAG ATCACAAGAT ATTGATGCTG ATGGACAGGG ATTTTGTCAA 
GGAGGATTCA GCATTGATTT TACTAAAGCT GACAGAGTAC TTCTTGGTGG TCCTGGTAGC 
TTTTATTGGC AAGGTCAGCT TATTTCGGAT CAAGTGGCAG AAATCGTATC TAAATACGAC 
CCCAATGTTT ACAGCATCAA GTATAATAAC CAATTAGCAA CTCGGACTGC ACAAGCTATT 
TTTGATGACA GCTATTTGGG TTATTCTGTG GCTGTCGGAG ATTTCAATGG TGATGGCATA 
GATGACTTTG TTTCAGGAGT TCCAAGAGCA GCAAGGACTT TGGGAATGGT TTATATTTAT 
GATGGGAAGA ACATGTCCTC CTTATACAAT TTTACTGGCG AGCAGATGGC TGCATATTTC 
GGATTTTCTG TAGCTGCCAC TGACATTAAT GGAGATGATT ATGCAGATGT GTTTATTGGA 
GCACCTCTCT TCATGGATCG TGGCTCTGAT GGCAAACTCC AAGAGGTGGG GCAGGTCTCA 
GTGTCTCTAC AGAGAGCTTC AGGAGACTTC CAGACGACAA AGCTGAATGG ATTTGAGGTC 
TTTGCACGGT TTGGCAGTGC CATAGCTCCT TTGGGAGATC TGGACCAGGA TGGTTTCAAT 
GATATTGCAA TTGCTGCTCC ATATGGGGGT GAAGATAAAA AAGGAATTGT TTATATCTTC 
AATGGAAGAT CAACAGGCTT GAACGCAGTC CCATCTCAAA TCCTTGAAGG GCAGTGGGCT 
GCTCGAAGCA TGCCACCAAG CTTTGGCTAT TCAATGAAAG GAGCCACAGA TATAGACAAA 
AATGGATATC CAGACTTAAT TGTAGGAGCT TTTGGTGTAG ATCGAGCTAT CTTATACAGG 
GCCAGACCAG TTATCACTGT AAATGCTGGT CTTGAAGTGT ACCCTAGCAT TTTAAATCAA 
GACAATAAAA CCTGCTCACT GCCTGGAACA GCTCTCAAAG TTTCCTGTTT TAATGTTAGG 
TTCTGCTTAA AGGCAGATGG CAAAGGAGTA CTTCCCAGGA AACTTAATTT CCAGGTGGAA 
CTTCTTTTGG ATAAACTCAA GCAAAAGGGA GCAATTCGAC GAGCACTGTT TCTCTACAGC 
AGGTCCCCAA GTCACTCCAA GAACATGACT ATTTCAAGGG GGGGACTGAT GCAGTGTGAG 
GAATTGATAG CGTATCTGCG GGATGAATCT GAATTTAGAG ACAAACTCAC TCCAATTACT 
ATTTTTATGG AATATCGGTT GGATTATAGA ACAGCTGCTG ATACAACAGG CTTGCAACCC 
ATTCTTAACC AGTTCACGCC TGCTAACATT AGTCGACAGG CTCACATTCT ACTTGACTGT 
GGTGAAGACA ATGTCTGTAA ACCCAAGCTG GAAGTTTCTG TAGATAGTGA TCAAAAGAAG 
ATCTATATTG GGGATGACAA CCCTCTGACA TTGATTGTTA AGGCTCAGAA TCAAGGAGAA 
GGTGCCTACG AAGCTGAGCT CATCGTTTCC ATTCCACTGC AGGCTGATTT CATCGGGGTT 
GTCCGAAACA ATGAAGCCTT AGCAAGACTT TCCTGTGCAT TTAAGACAGA AAACCAAACT 
CGCCAGGTGG TATGTGACCT TGGAAACCCA ATGAAGGCTG GAACTCAACT CTTAGCTGGT 
CTTCGTTTCA GTGTGCACCA GCAGTCAGAG ATGGATACTT CTGTGAAATT TGACTTACAA 
ATCCAAAGCT CAAATCTATT TGACAAAGTA AGCCCAGTTG TATCTCACAA AGTTGATCTT 
GCTGTTTTAG CTGCAGTTGA GATAAGAGGA GTCTCGAGTC CTGATCATAT CTTTCTTCCG 
ATTCCAAACT GGGAGCACAA GGAGAACCCT GAGACTGAAG AAGATGTTGG GCCAGTTGTT 
CAGCACATCT ATGAGCTGAG AAACAATGGT CCAAGTTCAT TCAGCAAGGC AATGCTCCAT 
CTTCAGTGGC CTTACAAATA TAATAATAAC ACTCTGTTGT ATATCCTTCA TTATGATATT 
GATGGACCAA TGAACTGCAC TTCAGATATG GAGATCAACC CTTTGAGAAT TAAGATCTCA 
TCTTTGCAAA CAACTGAAAA GAATGACACG GTTGCCGGGC AAGGTGAGCG GGACCATCTC 
ATCACTAAGC GGGATCTTGC CCTCAGTGAA GGAGATATTC ACACTTTGGG TTGTGGAGTT 
GCTCAGTGCT TGAAGATTGT CTGCCAAGTT GGGAGATTAG ACAGAGGAAA GAGTGCAATC 
TTGTACGTAA AGTCATTACT GTGGACTGAG ACTTTTATGA ATAAAGAAAA TCAGAATCAT 
TCCTATTCTC TGAAGTCGTC TGCTTCATTT AATGTCATAG AGTTTCCTTA TAAGAATCTT 
CCAATTGAGG ATATCACCAA CTCCACATTG GTTACCACTA ATGTCACCTG GGGCATTCAG 
CCAGCGCCCA TGCCTGTGCC TGTGTGGGTG ATCATTTTAG CAGTTCTAGC AGGATTGTTG 
CTACTGGCTG TTTTGGTATT TGTAATGTAC AGGATGGGCT TTTTTAAACG GGTCCGGCCA 
CCTCAAGAAG AACAAGAAAG GGAGCAGCTT CAACCTCATG AAAATGGTGA AGGAAACTCA 
GAAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138471.1
CDS	131..3139
Translation	MLLGTLLLILYILMLCRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	NM_001144999.2
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001144999.2

ORF Insert Sequence:

ATGCTCCTAG GCACCCTCCT TCTGATCCTG TACATCTTAA TGTTGTGCCG GATGTTTCTT 
CTCGTGGGAG CTCCCAAAGC AAACACCACC CAGCCTGGGA TTGTGGAAGG AGGGCAGGTC 
CTCAAATGTG ACTGGTCTTC TACCCGCCGG TGCCAGCCAA TTGAATTTGA TGCAACAGGC 
AATAGAGATT ATGCCAAGGA TGATCCATTG GAATTTAAGT CCCATCAGTG GTTTGGAGCA 
TCTGTGAGGT CGAAACAGGA TAAAATTTTG GCCTGTGCCC CATTGTACCA TTGGAGAACT 
GAGATGAAAC AGGAGCGAGA GCCTGTTGGA ACATGCTTTC TTCAAGATGG AACAAAGACT 
GTTGAGTATG CTCCATGTAG ATCACAAGAT ATTGATGCTG ATGGACAGGG ATTTTGTCAA 
GGAGGATTCA GCATTGATTT TACTAAAGCT GACAGAGTAC TTCTTGGTGG TCCTGGTAGC 
TTTTATTGGC AAGGTCAGCT TATTTCGGAT CAAGTGGCAG AAATCGTATC TAAATACGAC 
CCCAATGTTT ACAGCATCAA GTATAATAAC CAATTAGCAA CTCGGACTGC ACAAGCTATT 
TTTGATGACA GCTATTTGGG TTATTCTGTG GCTGTCGGAG ATTTCAATGG TGATGGCATA 
GATGACTTTG TTTCAGGAGT TCCAAGAGCA GCAAGGACTT TGGGAATGGT TTATATTTAT 
GATGGGAAGA ACATGTCCTC CTTATACAAT TTTACTGGCG AGCAGATGGC TGCATATTTC 
GGATTTTCTG TAGCTGCCAC TGACATTAAT GGAGATGATT ATGCAGATGT GTTTATTGGA 
GCACCTCTCT TCATGGATCG TGGCTCTGAT GGCAAACTCC AAGAGGTGGG GCAGGTCTCA 
GTGTCTCTAC AGAGAGCTTC AGGAGACTTC CAGACGACAA AGCTGAATGG ATTTGAGGTC 
TTTGCACGGT TTGGCAGTGC CATAGCTCCT TTGGGAGATC TGGACCAGGA TGGTTTCAAT 
GATATTGCAA TTGCTGCTCC ATATGGGGGT GAAGATAAAA AAGGAATTGT TTATATCTTC 
AATGGAAGAT CAACAGGCTT GAACGCAGTC CCATCTCAAA TCCTTGAAGG GCAGTGGGCT 
GCTCGAAGCA TGCCACCAAG CTTTGGCTAT TCAATGAAAG GAGCCACAGA TATAGACAAA 
AATGGATATC CAGACTTAAT TGTAGGAGCT TTTGGTGTAG ATCGAGCTAT CTTATACAGG 
GCCAGACCAG TTATCACTGT AAATGCTGGT CTTGAAGTGT ACCCTAGCAT TTTAAATCAA 
GACAATAAAA CCTGCTCACT GCCTGGAACA GCTCTCAAAG TTTCCTGTTT TAATGTTAGG 
TTCTGCTTAA AGGCAGATGG CAAAGGAGTA CTTCCCAGGA AACTTAATTT CCAGGTGGAA 
CTTCTTTTGG ATAAACTCAA GCAAAAGGGA GCAATTCGAC GAGCACTGTT TCTCTACAGC 
AGGTCCCCAA GTCACTCCAA GAACATGACT ATTTCAAGGG GGGGACTGAT GCAGTGTGAG 
GAATTGATAG CGTATCTGCG GGATGAATCT GAATTTAGAG ACAAACTCAC TCCAATTACT 
ATTTTTATGG AATATCGGTT GGATTATAGA ACAGCTGCTG ATACAACAGG CTTGCAACCC 
ATTCTTAACC AGTTCACGCC TGCTAACATT AGTCGACAGG CTCACATTCT ACTTGACTGT 
GGTGAAGACA ATGTCTGTAA ACCCAAGCTG GAAGTTTCTG TAGATAGTGA TCAAAAGAAG 
ATCTATATTG GGGATGACAA CCCTCTGACA TTGATTGTTA AGGCTCAGAA TCAAGGAGAA 
GGTGCCTACG AAGCTGAGCT CATCGTTTCC ATTCCACTGC AGGCTGATTT CATCGGGGTT 
GTCCGAAACA ATGAAGCCTT AGCAAGACTT TCCTGTGCAT TTAAGACAGA AAACCAAACT 
CGCCAGGTGG TATGTGACCT TGGAAACCCA ATGAAGGCTG GAACTCAACT CTTAGCTGGT 
CTTCGTTTCA GTGTGCACCA GCAGTCAGAG ATGGATACTT CTGTGAAATT TGACTTACAA 
ATCCAAAGCT CAAATCTATT TGACAAAGTA AGCCCAGTTG TATCTCACAA AGTTGATCTT 
GCTGTTTTAG CTGCAGTTGA GATAAGAGGA GTCTCGAGTC CTGATCATAT CTTTCTTCCG 
ATTCCAAACT GGGAGCACAA GGAGAACCCT GAGACTGAAG AAGATGTTGG GCCAGTTGTT 
CAGCACATCT ATGAGCTGAG AAACAATGGT CCAAGTTCAT TCAGCAAGGC AATGCTCCAT 
CTTCAGTGGC CTTACAAATA TAATAATAAC ACTCTGTTGT ATATCCTTCA TTATGATATT 
GATGGACCAA TGAACTGCAC TTCAGATATG GAGATCAACC CTTTGAGAAT TAAGATCTCA 
TCTTTGCAAA CAACTGAAAA GAATGACACG GTTGCCGGGC AAGGTGAGCG GGACCATCTC 
ATCACTAAGC GGGATCTTGC CCTCAGTGAA GGAGATATTC ACACTTTGGG TTGTGGAGTT 
GCTCAGTGCT TGAAGATTGT CTGCCAAGTT GGGAGATTAG ACAGAGGAAA GAGTGCAATC 
TTGTACGTAA AGTCATTACT GTGGACTGAG ACTTTTATGA ATAAAGAAAA TCAGAATCAT 
TCCTATTCTC TGAAGTCGTC TGCTTCATTT AATGTCATAG AGTTTCCTTA TAAGAATCTT 
CCAATTGAGG ATATCACCAA CTCCACATTG GTTACCACTA ATGTCACCTG GGGCATTCAG 
CCAGCGCCCA TGCCTGTGCC TGTGTGGGTG ATCATTTTAG CAGTTCTAGC AGGATTGTTG 
CTACTGGCTG TTTTGGTATT TGTAATGTAC AGGATGGGCT TTTTTAAACG GGTCCGGCCA 
CCTCAAGAAG AACAAGAAAG GGAGCAGCTT CAACCTCATG AAAATGGTGA AGGAAACTCA 
GAAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGAV ( NM_001145000.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138472.1 Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3, mRNA.

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CloneID	OHu27622
Clone ID Related Accession (Same CDS sequence)	NM_001145000.2
Accession Version	NM_001145000.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3039bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550851200000
Organism	Homo sapiens(human)
Product	integrin alpha-V isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK309711.1, BC144100.1, BC136442.1, DA736912.1, CB962576.1, CN409399.1, BC047454.1 and BQ101180.1. On May 10, 2013 this sequence version replaced NM_001145000.1. Transcript Variant: This variant (3) lacks two alternate in-frame exons in the coding region compared to variant 1. This results in a shorter protein (isoform 3) compared to isoform 1. It is not known whether this isoform (3) is proteolytically processed in the same manner as isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209894.1, SRR1660809.12945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACGTCAGCT TATTTCGGAT 
CAAGTGGCAG AAATCGTATC TAAATACGAC CCCAATGTTT ACAGCATCAA GTATAATAAC 
CAATTAGCAA CTCGGACTGC ACAAGCTATT TTTGATGACA GCTATTTGGG TTATTCTGTG 
GCTGTCGGAG ATTTCAATGG TGATGGCATA GATGACTTTG TTTCAGGAGT TCCAAGAGCA 
GCAAGGACTT TGGGAATGGT TTATATTTAT GATGGGAAGA ACATGTCCTC CTTATACAAT 
TTTACTGGCG AGCAGATGGC TGCATATTTC GGATTTTCTG TAGCTGCCAC TGACATTAAT 
GGAGATGATT ATGCAGATGT GTTTATTGGA GCACCTCTCT TCATGGATCG TGGCTCTGAT 
GGCAAACTCC AAGAGGTGGG GCAGGTCTCA GTGTCTCTAC AGAGAGCTTC AGGAGACTTC 
CAGACGACAA AGCTGAATGG ATTTGAGGTC TTTGCACGGT TTGGCAGTGC CATAGCTCCT 
TTGGGAGATC TGGACCAGGA TGGTTTCAAT GATATTGCAA TTGCTGCTCC ATATGGGGGT 
GAAGATAAAA AAGGAATTGT TTATATCTTC AATGGAAGAT CAACAGGCTT GAACGCAGTC 
CCATCTCAAA TCCTTGAAGG GCAGTGGGCT GCTCGAAGCA TGCCACCAAG CTTTGGCTAT 
TCAATGAAAG GAGCCACAGA TATAGACAAA AATGGATATC CAGACTTAAT TGTAGGAGCT 
TTTGGTGTAG ATCGAGCTAT CTTATACAGG GCCAGACCAG TTATCACTGT AAATGCTGGT 
CTTGAAGTGT ACCCTAGCAT TTTAAATCAA GACAATAAAA CCTGCTCACT GCCTGGAACA 
GCTCTCAAAG TTTCCTGTTT TAATGTTAGG TTCTGCTTAA AGGCAGATGG CAAAGGAGTA 
CTTCCCAGGA AACTTAATTT CCAGGTGGAA CTTCTTTTGG ATAAACTCAA GCAAAAGGGA 
GCAATTCGAC GAGCACTGTT TCTCTACAGC AGGTCCCCAA GTCACTCCAA GAACATGACT 
ATTTCAAGGG GGGGACTGAT GCAGTGTGAG GAATTGATAG CGTATCTGCG GGATGAATCT 
GAATTTAGAG ACAAACTCAC TCCAATTACT ATTTTTATGG AATATCGGTT GGATTATAGA 
ACAGCTGCTG ATACAACAGG CTTGCAACCC ATTCTTAACC AGTTCACGCC TGCTAACATT 
AGTCGACAGG CTCACATTCT ACTTGACTGT GGTGAAGACA ATGTCTGTAA ACCCAAGCTG 
GAAGTTTCTG TAGATAGTGA TCAAAAGAAG ATCTATATTG GGGATGACAA CCCTCTGACA 
TTGATTGTTA AGGCTCAGAA TCAAGGAGAA GGTGCCTACG AAGCTGAGCT CATCGTTTCC 
ATTCCACTGC AGGCTGATTT CATCGGGGTT GTCCGAAACA ATGAAGCCTT AGCAAGACTT 
TCCTGTGCAT TTAAGACAGA AAACCAAACT CGCCAGGTGG TATGTGACCT TGGAAACCCA 
ATGAAGGCTG GAACTCAACT CTTAGCTGGT CTTCGTTTCA GTGTGCACCA GCAGTCAGAG 
ATGGATACTT CTGTGAAATT TGACTTACAA ATCCAAAGCT CAAATCTATT TGACAAAGTA 
AGCCCAGTTG TATCTCACAA AGTTGATCTT GCTGTTTTAG CTGCAGTTGA GATAAGAGGA 
GTCTCGAGTC CTGATCATAT CTTTCTTCCG ATTCCAAACT GGGAGCACAA GGAGAACCCT 
GAGACTGAAG AAGATGTTGG GCCAGTTGTT CAGCACATCT ATGAGCTGAG AAACAATGGT 
CCAAGTTCAT TCAGCAAGGC AATGCTCCAT CTTCAGTGGC CTTACAAATA TAATAATAAC 
ACTCTGTTGT ATATCCTTCA TTATGATATT GATGGACCAA TGAACTGCAC TTCAGATATG 
GAGATCAACC CTTTGAGAAT TAAGATCTCA TCTTTGCAAA CAACTGAAAA GAATGACACG 
GTTGCCGGGC AAGGTGAGCG GGACCATCTC ATCACTAAGC GGGATCTTGC CCTCAGTGAA 
GGAGATATTC ACACTTTGGG TTGTGGAGTT GCTCAGTGCT TGAAGATTGT CTGCCAAGTT 
GGGAGATTAG ACAGAGGAAA GAGTGCAATC TTGTACGTAA AGTCATTACT GTGGACTGAG 
ACTTTTATGA ATAAAGAAAA TCAGAATCAT TCCTATTCTC TGAAGTCGTC TGCTTCATTT 
AATGTCATAG AGTTTCCTTA TAAGAATCTT CCAATTGAGG ATATCACCAA CTCCACATTG 
GTTACCACTA ATGTCACCTG GGGCATTCAG CCAGCGCCCA TGCCTGTGCC TGTGTGGGTG 
ATCATTTTAG CAGTTCTAGC AGGATTGTTG CTACTGGCTG TTTTGGTATT TGTAATGTAC 
AGGATGGGCT TTTTTAAACG GGTCCGGCCA CCTCAAGAAG AACAAGAAAG GGAGCAGCTT 
CAACCTCATG AAAATGGTGA AGGAAACTCA GAAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138472.1
CDS	277..3315
Translation	MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Target ORF information:

RefSeq Version	NM_001145000.2
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha V (ITGAV), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145000.2

ORF Insert Sequence:

ATGGCTTTTC CGCCGCGGCG ACGGCTGCGC CTCGGTCCCC GCGGCCTCCC GCTTCTTCTC 
TCGGGACTCC TGCTACCTCT GTGCCGCGCC TTCAACCTAG ACGTGGACAG TCCTGCCGAG 
TACTCTGGCC CCGAGGGAAG TTACTTCGGC TTCGCCGTGG ATTTCTTCGT GCCCAGCGCG 
TCTTCCCGGA TGTTTCTTCT CGTGGGAGCT CCCAAAGCAA ACACCACCCA GCCTGGGATT 
GTGGAAGGAG GGCAGGTCCT CAAATGTGAC TGGTCTTCTA CCCGCCGGTG CCAGCCAATT 
GAATTTGATG CAACAGGCAA TAGAGATTAT GCCAAGGATG ATCCATTGGA ATTTAAGTCC 
CATCAGTGGT TTGGAGCATC TGTGAGGTCG AAACAGGATA AAATTTTGGC CTGTGCCCCA 
TTGTACCATT GGAGAACTGA GATGAAACAG GAGCGAGAGC CTGTTGGAAC ATGCTTTCTT 
CAAGATGGAA CAAAGACTGT TGAGTATGCT CCATGTAGAT CACGTCAGCT TATTTCGGAT 
CAAGTGGCAG AAATCGTATC TAAATACGAC CCCAATGTTT ACAGCATCAA GTATAATAAC 
CAATTAGCAA CTCGGACTGC ACAAGCTATT TTTGATGACA GCTATTTGGG TTATTCTGTG 
GCTGTCGGAG ATTTCAATGG TGATGGCATA GATGACTTTG TTTCAGGAGT TCCAAGAGCA 
GCAAGGACTT TGGGAATGGT TTATATTTAT GATGGGAAGA ACATGTCCTC CTTATACAAT 
TTTACTGGCG AGCAGATGGC TGCATATTTC GGATTTTCTG TAGCTGCCAC TGACATTAAT 
GGAGATGATT ATGCAGATGT GTTTATTGGA GCACCTCTCT TCATGGATCG TGGCTCTGAT 
GGCAAACTCC AAGAGGTGGG GCAGGTCTCA GTGTCTCTAC AGAGAGCTTC AGGAGACTTC 
CAGACGACAA AGCTGAATGG ATTTGAGGTC TTTGCACGGT TTGGCAGTGC CATAGCTCCT 
TTGGGAGATC TGGACCAGGA TGGTTTCAAT GATATTGCAA TTGCTGCTCC ATATGGGGGT 
GAAGATAAAA AAGGAATTGT TTATATCTTC AATGGAAGAT CAACAGGCTT GAACGCAGTC 
CCATCTCAAA TCCTTGAAGG GCAGTGGGCT GCTCGAAGCA TGCCACCAAG CTTTGGCTAT 
TCAATGAAAG GAGCCACAGA TATAGACAAA AATGGATATC CAGACTTAAT TGTAGGAGCT 
TTTGGTGTAG ATCGAGCTAT CTTATACAGG GCCAGACCAG TTATCACTGT AAATGCTGGT 
CTTGAAGTGT ACCCTAGCAT TTTAAATCAA GACAATAAAA CCTGCTCACT GCCTGGAACA 
GCTCTCAAAG TTTCCTGTTT TAATGTTAGG TTCTGCTTAA AGGCAGATGG CAAAGGAGTA 
CTTCCCAGGA AACTTAATTT CCAGGTGGAA CTTCTTTTGG ATAAACTCAA GCAAAAGGGA 
GCAATTCGAC GAGCACTGTT TCTCTACAGC AGGTCCCCAA GTCACTCCAA GAACATGACT 
ATTTCAAGGG GGGGACTGAT GCAGTGTGAG GAATTGATAG CGTATCTGCG GGATGAATCT 
GAATTTAGAG ACAAACTCAC TCCAATTACT ATTTTTATGG AATATCGGTT GGATTATAGA 
ACAGCTGCTG ATACAACAGG CTTGCAACCC ATTCTTAACC AGTTCACGCC TGCTAACATT 
AGTCGACAGG CTCACATTCT ACTTGACTGT GGTGAAGACA ATGTCTGTAA ACCCAAGCTG 
GAAGTTTCTG TAGATAGTGA TCAAAAGAAG ATCTATATTG GGGATGACAA CCCTCTGACA 
TTGATTGTTA AGGCTCAGAA TCAAGGAGAA GGTGCCTACG AAGCTGAGCT CATCGTTTCC 
ATTCCACTGC AGGCTGATTT CATCGGGGTT GTCCGAAACA ATGAAGCCTT AGCAAGACTT 
TCCTGTGCAT TTAAGACAGA AAACCAAACT CGCCAGGTGG TATGTGACCT TGGAAACCCA 
ATGAAGGCTG GAACTCAACT CTTAGCTGGT CTTCGTTTCA GTGTGCACCA GCAGTCAGAG 
ATGGATACTT CTGTGAAATT TGACTTACAA ATCCAAAGCT CAAATCTATT TGACAAAGTA 
AGCCCAGTTG TATCTCACAA AGTTGATCTT GCTGTTTTAG CTGCAGTTGA GATAAGAGGA 
GTCTCGAGTC CTGATCATAT CTTTCTTCCG ATTCCAAACT GGGAGCACAA GGAGAACCCT 
GAGACTGAAG AAGATGTTGG GCCAGTTGTT CAGCACATCT ATGAGCTGAG AAACAATGGT 
CCAAGTTCAT TCAGCAAGGC AATGCTCCAT CTTCAGTGGC CTTACAAATA TAATAATAAC 
ACTCTGTTGT ATATCCTTCA TTATGATATT GATGGACCAA TGAACTGCAC TTCAGATATG 
GAGATCAACC CTTTGAGAAT TAAGATCTCA TCTTTGCAAA CAACTGAAAA GAATGACACG 
GTTGCCGGGC AAGGTGAGCG GGACCATCTC ATCACTAAGC GGGATCTTGC CCTCAGTGAA 
GGAGATATTC ACACTTTGGG TTGTGGAGTT GCTCAGTGCT TGAAGATTGT CTGCCAAGTT 
GGGAGATTAG ACAGAGGAAA GAGTGCAATC TTGTACGTAA AGTCATTACT GTGGACTGAG 
ACTTTTATGA ATAAAGAAAA TCAGAATCAT TCCTATTCTC TGAAGTCGTC TGCTTCATTT 
AATGTCATAG AGTTTCCTTA TAAGAATCTT CCAATTGAGG ATATCACCAA CTCCACATTG 
GTTACCACTA ATGTCACCTG GGGCATTCAG CCAGCGCCCA TGCCTGTGCC TGTGTGGGTG 
ATCATTTTAG CAGTTCTAGC AGGATTGTTG CTACTGGCTG TTTTGGTATT TGTAATGTAC 
AGGATGGGCT TTTTTAAACG GGTCCGGCCA CCTCAAGAAG AACAAGAAAG GGAGCAGCTT 
CAACCTCATG AAAATGGTGA AGGAAACTCA GAAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.
The Journal of cell biology218(10)3506-3525(2019 Oct)
Nakamura K,Ikeuchi T,Nara K,Rhodes CS,Zhang P,Chiba Y,Kazuno S,Miura Y,Ago T,Arikawa-Hirasawa E,Mukouyama YS,Yamada Y

Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling.
Journal of immunology (Baltimore, Md. : 1950)203(5)1383-1391(2019 Sep)
Takada YK,Yu J,Shimoda M,Takada Y

Hypoxia-driven paracrine osteopontin/integrin αvβ3 signaling promotes pancreatic cancer cell epithelial-mesenchymal transition and cancer stem cell-like properties by modulating forkhead box protein M1.
Molecular oncology13(2)228-245(2019 02)
Cao J,Li J,Sun L,Qin T,Xiao Y,Chen K,Qian W,Duan W,Lei J,Ma J,Ma Q,Han L

Plasmodium falciparum infected erythrocytes can bind to host receptors integrins αVβ3 and αVβ6 through DBLδ1_D4 domain of PFL2665c PfEMP1 protein.
Scientific reports8(1)17871(2018 12)
Chesnokov O,Merritt J,Tcherniuk SO,Milman N,Oleinikov AV

Inhibition of skin carcinogenesis by suppression of NF-κB dependent ITGAV and TIMP-1 expression in IL-32γ overexpressed condition.
Journal of experimental & clinical cancer research : CR37(1)293(2018 Nov)
Lee YS,Lee CH,Bae JT,Nam KT,Moon DB,Hwang OK,Choi JS,Kim TH,Jun HO,Jung YS,Hwang DY,Han SB,Yoon DY,Hong JT

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ITGAV cDNA ORF clone, Homo sapiens(human)

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