| Gene Symbol | IL2 |
| Entrez Gene ID | 3558 |
| Full Name | interleukin 2 |
| Synonyms | IL-2,TCGF,lymphokine |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | Severe combined immunodeficiency due to IL2 deficiency (1) |

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