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About the Vesicle-mediated transport pathway
The transit of proteins and other cargo through the cell requires a cellular transport process in which transported substances are moved in membrane-bounded vesicles. Transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The transport process begins with the formation of the vesicle itself, often triggered by the interaction of the cargo with the vesicle formation machinery. Vesicular transport pathways can include vesicle formation, coating, budding, uncoating and target membrane fusion depending upon the function of the pathway described. Vesicle-mediated transport occurs from within cell via ER and Golgi transport, as well as functioning in the endocytosis of material taken into the cell via scavenger receptors.
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| Gene Symbol | Full Name |
|---|---|
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALB | albumin |
| AMBP | alpha-1-microglobulin/bikunin precursor |
| APOA1 | apolipoprotein A-I |
| APOB | apolipoprotein B |
| APOE | apolipoprotein E |
| APP | amyloid beta (A4) precursor protein |
| ARCN1 | archain 1 |
| ARF1 | ADP-ribosylation factor 1 |
| ARRB1 | arrestin, beta 1 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CALR | calreticulin |
| CD36 | CD36 molecule (thrombospondin receptor) |
| SCARB1 | scavenger receptor class B, member 1 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit |
| CLTA | clathrin, light chain A |
| CLTB | clathrin, light chain B |
| CLTC | clathrin, heavy chain (Hc) |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| COPA | coatomer protein complex, subunit alpha |
| COPB1 | coatomer protein complex, subunit beta 1 |
| CPD | carboxypeptidase D |
| CTSZ | cathepsin Z |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DNM1 | dynamin 1 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DNM2 | dynamin 2 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTL | ferritin, light polypeptide |
| GAK | cyclin G associated kinase |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GJA3 | gap junction protein, alpha 3, 46kDa |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GJA5 | gap junction protein, alpha 5, 40kDa |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GJB1 | gap junction protein, beta 1, 32kDa |
| GJB2 | gap junction protein, beta 2, 26kDa |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GJB5 | gap junction protein, beta 5, 31.1kDa |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| SFN | stratifin |
| HBA1 | hemoglobin, alpha 1 |
| HBA2 | hemoglobin, alpha 2 |
| HBB | hemoglobin, beta |
| HP | haptoglobin |
| HPR | haptoglobin-related protein |
| HPX | hemopexin |
| HSPA8 | heat shock 70kDa protein 8 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| IGF2R | insulin-like growth factor 2 receptor |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IGHA2 | immunoglobulin heavy constant alpha 2 (A2m marker) |
| IGKC | immunoglobulin kappa constant |
| IGLC1 | immunoglobulin lambda constant 1 (Mcg marker) |
| IGLC2 | immunoglobulin lambda constant 2 (Kern-Oz- marker) |
| IGLC3 | immunoglobulin lambda constant 3 (Kern-Oz+ marker) |
| IGLC6 | immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| M6PR | mannose-6-phosphate receptor (cation dependent) |
| RAB8A | RAB8A, member RAS oncogene family |
| MSR1 | macrophage scavenger receptor 1 |
| MYH1 | myosin, heavy chain 1, skeletal muscle, adult |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| MYH4 | myosin, heavy chain 4, skeletal muscle |
| MYH6 | myosin, heavy chain 6, cardiac muscle, alpha |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
| MYH8 | myosin, heavy chain 8, skeletal muscle, perinatal |
| MYO1C | myosin IC |
| MYO5A | myosin VA (heavy chain 12, myoxin) |
| MYO6 | myosin VI |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| RAB4A | RAB4A, member RAS oncogene family |
| RAB13 | RAB13, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RPS27A | ribosomal protein S27a |
| SORT1 | sortilin 1 |
| SAA1 | serum amyloid A1 |
| SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component |