tlr4bb cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	tlr4bb
Entrez Gene ID	403132
Full Name	toll-like receptor 4b, duplicate b
Synonyms	tlr4b
General protein information	Preferred Names toll-like receptor 4b, duplicate b Names toll-like receptor 4b, duplicate b TIR4.2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_212813.2	NP_997978.2	toll-like receptor 4b, duplicate b precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tlr4	NP_067272.1
Danio rerio (zebrafish)	tlr4ba	NP_001124523.1
Pan troglodytes (chimpanzee)	TLR4	NP_001138335.1
Gallus gallus (chicken)	TLR4	NP_001025864.1
Danio rerio (zebrafish)	tlr4al	XP_001919699.4
Homo sapiens (human)	TLR4	NP_612564.1
Macaca mulatta (Rhesus monkey)	TLR4	NP_001032169.1
Rattus norvegicus (Norway rat)	Tlr4	NP_062051.1
Danio rerio (zebrafish)	tlr4bb	NP_997978.1
Canis lupus familiaris (dog)	TLR4	NP_001002950.2
Bos taurus (cattle)	TLR4	NP_776623.5

Gene Ontology
Bibliography

Related articles in PubMed

A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae.
Icoglu Aksakal F, Ciltas A, Simsek Ozek N
Chemosphere225820-828(2019 Jun)

Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos.
Xiong G, Zou L, Deng Y, Meng Y, Liao X, Lu H
Fish & shellfish immunology86549-558(2019 Mar)

Transcriptomic analysis of zebrafish (Danio rerio) embryos to assess integrated biotoxicity of Xitiaoxi River waters.
Zhou S, Wei Z, Chu T, Yu H, Li S, Zhang W, Gui W
Environmental pollution (Barking, Essex : 1987)242(Pt A)42-53(2018 Nov)

Outcome of co-infection with opportunistic and multidrug resistant Aeromonas hydrophila and A. veronii in zebrafish: Identification, characterization, pathogenicity and immune responses.
Chandrarathna HPSU, Nikapitiya C, Dananjaya SHS, Wijerathne CUB, Wimalasena SHMP, Kwun HJ, Heo GJ, Lee J, De Zoysa M
Fish & shellfish immunology80573-581(2018 Sep)

β-Glucan-Producing
Pérez-Ramos A, Mohedano ML, Pardo MÁ, López P
Frontiers in microbiology91684(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following tlr4bb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tlr4bb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa53248	NM_212813.2 Latest version!	Danio rerio toll-like receptor 4b, duplicate b (tlr4bb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

tlr4bb ( NM_212813.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_997978.2 Danio rerio toll-like receptor 4b, duplicate b (tlr4bb), mRNA.

Price & Availability↑

CloneID	ODa53248
Clone ID Related Accession (Same CDS sequence)	NM_212813.2
Accession Version	NM_212813.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2460bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576771200000
Organism	Danio rerio(zebrafish)
Product	toll-like receptor 4b, duplicate b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX908770.13 and AY388400.1. On Jan 30, 2016 this sequence version replaced NM_212813.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068358.1, AY388400.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGATCATGT CAAATGGGGA ACGGATGATT TTCCTAAGTT CAATCTTTAT TCTTGTGAAT 
GCTGGACAAG GACAGGAATG TACCGAGCTG ATAAAGAATA AGGAATATTC ATGTTCTGGA 
AGGAATCTGA CTTGTATTCC TGGTAGTCTT CCCTTCTCTG TGGCATCTCT GGATTTCAGT 
TTCAATTTCT TGACCTCATT ACATAAGCGT GTATTTCCTG TGATGTTGAA TTTACAACTC 
CTGGATCTCA CAAGATGCTA CATCAGACAG ATTGAAAAAG ATGCTTTCTA CAATGTGAAA 
AATTTGATGA CATTGATTCT TACTGGAAAC CCTATAACAT ATTTAGCACC TGAATGCTTG 
AATTCTTTAT ACAAGCTGCA AAGACTAGTT CTTGTGGATG TTCGTCTTGA ATCCTTACAA 
CTTCAAATTA ATAACCTTAC CAAGCTACAG GACCTTAAAG TCGGAACAAA TTGCATCCAG 
TCCATGACTC TTCCTTCATT CATGAGCACC TTCAAAGACT TCAGTTTACT TGATCTACAT 
GCCAATAATA TATCCATCAT CAGAATGGAT CACACTGCTG TGTTGCGAGA GATTGGAAGA 
AATATGACGT TGATTCTGTC TAGGAATCCA TTAATACACA TTGAACCAGG AGCTTTCAAG 
GATGTCATTC TCAGAGAGCT TCATCTGCTA GCTGCCTTCA TTTCGTTTAA TGCACAAAAA 
GAGTGTCACA AAGCTCTCAC TGGCCTCACC GTGGATAAGT TGTTTGTGGG ACGTTACAGA 
ATGGACGAAA AAATCAAAGT GTCAGTTCCA GATTATCTTG AAGGTCTATG TTCAATTAAT 
TTTAACGAAA TTTATCTTGT TCAAAAAGAA TGGTCTGACT CAGAAATGCA CTTGTTTCGT 
TGTATGGTCA ATGCAACAAA AATCACAATA AAAAAAGCAT ATATGAACAG TATGAAACAT 
ATTCCATTCC ACCGTCTTAA GGAACTGTAT TTAAGTGACA CTGGATTATC TGTTGTACCA 
TTTATTTCAC ACATTCCAAG CTTGGAAAAA CTGGTGATGA AGAGTCCCTT TCCTATTACC 
TTCACTGGAG TCAGTGACCT TCCCCTGCTT CAATATGTAG ACTTGAGTGG AAACATGTTG 
ATTTTGCATG AATGCTGTTC CATTCTTTTT CCAAGGACAC CAAATATTCA ATACTTGAAT 
CTTAGTCAAA ACTCAGAAAT AACATTTGTT AATGAGCCAT TTTCTGCACT TGACTTGCTT 
GAAGTGTTGG ACTTCCACCA TACAAAACTA GTCATAGTTT TTTACTTTGG ATTCTTCAAA 
CATCTGAGAA ATTTAAAGTA TTTGGATATT TCTTATACAC GTGTTCATTT CAATACCTTG 
ACTTTTCAGG ACCTGCATAA TTTGACTGTT CTTAAAATGG CAGGAAACAG TTTTAGTGGA 
GATAAATTGA GTTACTTCTT ACAAAACCTA ACAAGCTTGG AGGTTCTTGA CATTTCACAG 
TGTGGCATTG AGAAAGTCTC CATGAGATCT TTTACTGGCA CGCAGAAACT ACGACATTTA 
TATTTAAGTC GAAACAAATT GATGGTTTTG GACTTTTTAA CTCAACCAGA GCTGACACAT 
CTTACATCAG TGTATATTGA TAAAAACAGT ATAACCACCA TCCCACTTGA TGTTCTACAA 
AAGTTGCCCA TGAACCTTTC TGAGTTTGAT TTGTCCTCTA ACTCCATCGA TTGCTCCTGC 
TCTCAGACTG ATTTTATTTT GTGGATTATT CAAAAACAAA ACATTTTAAA ACAACTGGAA 
AACATTCGGT GTAAAACTTT TTCTGCAAAT ACAGATTTCA AAGCAATAGA CTTTGACATT 
GACTACTGTG TGCACAAGAA AAGACTCACA ATTGTTTTAT CAGTAATTTG TGTTACGTTT 
GTAGTTGTGT TAGCAATTTT GCTTTATAAA TTCTGGTTCT ATGTTCAGTA TTGTTTTATT 
TTATTCAGTG GCTACAGATC ACCTGGACAG CAAGAATGTT CTTATGACGC ATTTGTGATT 
TTCTCCAGCT ATGATGAAGC TTGGGTCATG AATGAACTTA TGGAGAATCT GGAGAACGGT 
GTGCCACCTA TTCAGCTTTG CCTTCACATG CGGGACTTTC AAGCCGGGAA GTCAATCGCC 
TCCAACATTA TAGATGAAGG AATAATGGGC AGCCGTAAGA TCATTGTGGT TGTGTCTCAA 
CACTTCATTG ATAGTTCCTG GTGTCGCTTT GAGTTTGAAT TAGCTCAGTC TCGGTTTTTG 
ATGGAACGCA ATGCCAATAT CATCATCATT ATTCTGGAAG ATGTGGCGGA GAGAAAAACC 
AAGAAAGTGT TTGGTCTACA TAAGCATCTG AAGAAGAACA CATACCTGAA GTGGAGCAGA 
GACCCTTTGA GCAACATGAG ATTCTGGATA CGACTCAGGA AAGCAATTTT ACAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997978.2
CDS	197..2656
Translation	MIMSNGERMIFLSSIFILVNAGQGQECTELIKNKEYSCSGRNLTCIPGSLPFSVASLDFSFNFLTSLHKRVFPVMLNLQLLDLTRCYIRQIEKDAFYNVKNLMTLILTGNPITYLAPECLNSLYKLQRLVLVDVRLESLQLQINNLTKLQDLKVGTNCIQSMTLPSFMSTFKDFSLLDLHANNISIIRMDHTAVLREIGRNMTLILSRNPLIHIEPGAFKDVILRELHLLAAFISFNAQKECHKALTGLTVDKLFVGRYRMDEKIKVSVPDYLEGLCSINFNEIYLVQKEWSDSEMHLFRCMVNATKITIKKAYMNSMKHIPFHRLKELYLSDTGLSVVPFISHIPSLEKLVMKSPFPITFTGVSDLPLLQYVDLSGNMLILHECCSILFPRTPNIQYLNLSQNSEITFVNEPFSALDLLEVLDFHHTKLVIVFYFGFFKHLRNLKYLDISYTRVHFNTLTFQDLHNLTVLKMAGNSFSGDKLSYFLQNLTSLEVLDISQCGIEKVSMRSFTGTQKLRHLYLSRNKLMVLDFLTQPELTHLTSVYIDKNSITTIPLDVLQKLPMNLSEFDLSSNSIDCSCSQTDFILWIIQKQNILKQLENIRCKTFSANTDFKAIDFDIDYCVHKKRLTIVLSVICVTFVVVLAILLYKFWFYVQYCFILFSGYRSPGQQECSYDAFVIFSSYDEAWVMNELMENLENGVPPIQLCLHMRDFQAGKSIASNIIDEGIMGSRKIIVVVSQHFIDSSWCRFEFELAQSRFLMERNANIIIIILEDVAERKTKKVFGLHKHLKKNTYLKWSRDPLSNMRFWIRLRKAILQK

Target ORF information:

RefSeq Version	NM_212813.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio toll-like receptor 4b, duplicate b (tlr4bb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212813.2

ORF Insert Sequence:

ATGATCATGT CAAATGGGGA ACGGATGATT TTCCTAAGTT CAATCTTTAT TCTTGTGAAT 
GCTGGACAAG GACAGGAATG TACCGAGCTG ATAAAGAATA AGGAATATTC ATGTTCTGGA 
AGGAATCTGA CTTGTATTCC TGGTAGTCTT CCCTTCTCTG TGGCATCTCT GGATTTCAGT 
TTCAATTTCT TGACCTCATT ACATAAGCGT GTATTTCCTG TGATGTTGAA TTTACAACTC 
CTGGATCTCA CAAGATGCTA CATCAGACAG ATTGAAAAAG ATGCTTTCTA CAATGTGAAA 
AATTTGATGA CATTGATTCT TACTGGAAAC CCTATAACAT ATTTAGCACC TGAATGCTTG 
AATTCTTTAT ACAAGCTGCA AAGACTAGTT CTTGTGGATG TTCGTCTTGA ATCCTTACAA 
CTTCAAATTA ATAACCTTAC CAAGCTACAG GACCTTAAAG TCGGAACAAA TTGCATCCAG 
TCCATGACTC TTCCTTCATT CATGAGCACC TTCAAAGACT TCAGTTTACT TGATCTACAT 
GCCAATAATA TATCCATCAT CAGAATGGAT CACACTGCTG TGTTGCGAGA GATTGGAAGA 
AATATGACGT TGATTCTGTC TAGGAATCCA TTAATACACA TTGAACCAGG AGCTTTCAAG 
GATGTCATTC TCAGAGAGCT TCATCTGCTA GCTGCCTTCA TTTCGTTTAA TGCACAAAAA 
GAGTGTCACA AAGCTCTCAC TGGCCTCACC GTGGATAAGT TGTTTGTGGG ACGTTACAGA 
ATGGACGAAA AAATCAAAGT GTCAGTTCCA GATTATCTTG AAGGTCTATG TTCAATTAAT 
TTTAACGAAA TTTATCTTGT TCAAAAAGAA TGGTCTGACT CAGAAATGCA CTTGTTTCGT 
TGTATGGTCA ATGCAACAAA AATCACAATA AAAAAAGCAT ATATGAACAG TATGAAACAT 
ATTCCATTCC ACCGTCTTAA GGAACTGTAT TTAAGTGACA CTGGATTATC TGTTGTACCA 
TTTATTTCAC ACATTCCAAG CTTGGAAAAA CTGGTGATGA AGAGTCCCTT TCCTATTACC 
TTCACTGGAG TCAGTGACCT TCCCCTGCTT CAATATGTAG ACTTGAGTGG AAACATGTTG 
ATTTTGCATG AATGCTGTTC CATTCTTTTT CCAAGGACAC CAAATATTCA ATACTTGAAT 
CTTAGTCAAA ACTCAGAAAT AACATTTGTT AATGAGCCAT TTTCTGCACT TGACTTGCTT 
GAAGTGTTGG ACTTCCACCA TACAAAACTA GTCATAGTTT TTTACTTTGG ATTCTTCAAA 
CATCTGAGAA ATTTAAAGTA TTTGGATATT TCTTATACAC GTGTTCATTT CAATACCTTG 
ACTTTTCAGG ACCTGCATAA TTTGACTGTT CTTAAAATGG CAGGAAACAG TTTTAGTGGA 
GATAAATTGA GTTACTTCTT ACAAAACCTA ACAAGCTTGG AGGTTCTTGA CATTTCACAG 
TGTGGCATTG AGAAAGTCTC CATGAGATCT TTTACTGGCA CGCAGAAACT ACGACATTTA 
TATTTAAGTC GAAACAAATT GATGGTTTTG GACTTTTTAA CTCAACCAGA GCTGACACAT 
CTTACATCAG TGTATATTGA TAAAAACAGT ATAACCACCA TCCCACTTGA TGTTCTACAA 
AAGTTGCCCA TGAACCTTTC TGAGTTTGAT TTGTCCTCTA ACTCCATCGA TTGCTCCTGC 
TCTCAGACTG ATTTTATTTT GTGGATTATT CAAAAACAAA ACATTTTAAA ACAACTGGAA 
AACATTCGGT GTAAAACTTT TTCTGCAAAT ACAGATTTCA AAGCAATAGA CTTTGACATT 
GACTACTGTG TGCACAAGAA AAGACTCACA ATTGTTTTAT CAGTAATTTG TGTTACGTTT 
GTAGTTGTGT TAGCAATTTT GCTTTATAAA TTCTGGTTCT ATGTTCAGTA TTGTTTTATT 
TTATTCAGTG GCTACAGATC ACCTGGACAG CAAGAATGTT CTTATGACGC ATTTGTGATT 
TTCTCCAGCT ATGATGAAGC TTGGGTCATG AATGAACTTA TGGAGAATCT GGAGAACGGT 
GTGCCACCTA TTCAGCTTTG CCTTCACATG CGGGACTTTC AAGCCGGGAA GTCAATCGCC 
TCCAACATTA TAGATGAAGG AATAATGGGC AGCCGTAAGA TCATTGTGGT TGTGTCTCAA 
CACTTCATTG ATAGTTCCTG GTGTCGCTTT GAGTTTGAAT TAGCTCAGTC TCGGTTTTTG 
ATGGAACGCA ATGCCAATAT CATCATCATT ATTCTGGAAG ATGTGGCGGA GAGAAAAACC 
AAGAAAGTGT TTGGTCTACA TAAGCATCTG AAGAAGAACA CATACCTGAA GTGGAGCAGA 
GACCCTTTGA GCAACATGAG ATTCTGGATA CGACTCAGGA AAGCAATTTT ACAGAAATAA