tlr4al cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	tlr4al
Entrez Gene ID	795671
Full Name	toll-like receptor 4a, like
General protein information	Preferred Names toll-like receptor 4a, like Names toll-like receptor 4a, like
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001328605.1	NP_001315534.1	toll-like receptor 4a, like precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tlr4	NP_067272.1
Danio rerio (zebrafish)	tlr4ba	NP_001124523.1
Pan troglodytes (chimpanzee)	TLR4	NP_001138335.1
Gallus gallus (chicken)	TLR4	NP_001025864.1
Danio rerio (zebrafish)	tlr4al	XP_001919699.4
Homo sapiens (human)	TLR4	NP_612564.1
Macaca mulatta (Rhesus monkey)	TLR4	NP_001032169.1
Rattus norvegicus (Norway rat)	Tlr4	NP_062051.1
Danio rerio (zebrafish)	tlr4bb	NP_997978.1
Canis lupus familiaris (dog)	TLR4	NP_001002950.2
Bos taurus (cattle)	TLR4	NP_776623.5

Gene Ontology
Bibliography

Related articles in PubMed

A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae.
Icoglu Aksakal F, Ciltas A, Simsek Ozek N
Chemosphere225820-828(2019 Jun)

Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos.
Xiong G, Zou L, Deng Y, Meng Y, Liao X, Lu H
Fish & shellfish immunology86549-558(2019 Mar)

High-Fat Diet Consumption Induces Microbiota Dysbiosis and Intestinal Inflammation in Zebrafish.
Arias-Jayo N, Abecia L, Alonso-Sáez L, Ramirez-Garcia A, Rodriguez A, Pardo MA
Microbial ecology76(4)1089-1101(2018 Nov)

Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs).
Deng S, Jia PP, Zhang JH, Junaid M, Niu A, Ma YB, Fu A, Pei DS
Journal of hazardous materials357146-158(2018 09)

β-Glucan-Producing
Pérez-Ramos A, Mohedano ML, Pardo MÁ, López P
Frontiers in microbiology91684(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following tlr4al gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tlr4al cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa18662	NM_001328605.1 Latest version!	Danio rerio toll-like receptor 4a, like (tlr4al), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

tlr4al ( NM_001328605.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001315534.1 Danio rerio toll-like receptor 4a, like (tlr4al), mRNA.

Price & Availability↑

CloneID	ODa18662
Clone ID Related Accession (Same CDS sequence)	NM_001328605.1
Accession Version	NM_001328605.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2451bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576771200000
Organism	Danio rerio(zebrafish)
Product	toll-like receptor 4a, like precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX908770.13. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGAATTTCT TTACTATAAG TGCTTTCATA ATATATTTTC CAATAGGTGC TGGACAATCA 
TGCACAGAAA TTATTGAAAA TCTTCATTAT TCATGCATGG GAAGAAACCT AAGCTACATA 
CCATCCAGAA TTCCTTCCTC AGTTCAAACT CTTGATTTTA GTTTTAATGA CCTGAAATGG 
TTAAAGAAAA CTGTATTCCC AGTTTTCACT TTTCTGAGAG TTCTTGATCT GTCAAGATGC 
CACATCAGAC AGATTGAAAA CGATGCTTTC TACAATGTGA AGAATTTGAC TACTTTGTTC 
CTTACTGGAA ACCCTATTAT ATATTTTGCT CCTGGATGCT TGAATACTTT ATATAATCTG 
CAAAGGCTAG TTCTTGTGGA TATTGGTCTT GAATCCTTAC AGCTTAATAT TAATAACCTT 
ACCAAGCTAC AGGAACTCAA TGTTGGAACA AATTACATCC AGTCTATGAC TCTTCCTCCA 
TTCATGAGCA CCTTCAAAGA CTTCAGTTTA CTTGATCTAC ATGCCAACAA TATATCCATC 
ATCAGAACTA ATCACACCGT TGTGCTTCGA GAGATTGGAA AAAACATGAC ATTGATTCTC 
TCTAGGAATC CATTACTACA CATTGAACCA GGGTCTTTTA AAGGGGTTCA TCTTGTAGAG 
CTGGACATCC GATCCACATT TGTTTCGTTT GCTTCAAAGA AACAGGGTCT AAATGGTCTG 
CATGGCCTTA ATGTCACAAG GCTGATGTTT GGAATGTATA AAGATGATCC CAAACTTTAC 
CCATCAGATC TAGACTATTT CGATGGTCTT TGCTCTATTC ATTTTTATGA GGCATATTAT 
TACATGAAGG AAAGACTTGA CTGGAAAATG AATATCTTTC GCTGTATGAT TAATGCCACA 
GTTGTAGTTG TTAAGGGTGG TGTAATTCGT GTCATTGGGT ATGTGCCTTT TCATAAAATC 
AAGGAGCTTT ACTTGATTAA CACTCAGTTA TATACTGTGC CAGGTAAACA ACTTTCACAC 
ATTCGTACTT TAGAAAAATT TGTATTTACA CACAACAGTG CAACTCAAGT TGAAAAATTC 
TTAGACATGC CGAAACTTCA GTATGTGGAT CTTAATTCAA ACCAAATTAC TCTACAATCA 
TGCTGCATAG ATGTTTTATC TGGTACTCCT CAAATCAGAT ATTTAAATTT GAGCTTAAAT 
CCACAAATTT CTCTTGATAA AGGAGGATTT GAAGGACTTG AATCCCTAGA AATTTTAGAT 
TTTCATCATA CAAAGCTTTT AGGTATAGGA TCTTTTACAC TTTTGTCTAA TTTAAAAAAT 
CTGAGGTATC TGGATATTTC TTATTCAAGC GTAACCTTTG TTAACGTATA TTGCTTTTAT 
GGACTGAGCA GTCTTAAAGT TCTCAAGATG GCTGGCAATA GTTTTCAAGG TGATGTAGCA 
AATTATTTAT TTAACAATCT TACATTTTTA GAGCACCTTG ATATTTCATA CTGTCATGTG 
ATAGAAATAC ATTTAACGTC ATTTAAAAAC CTTCAAAGAC TTAGACATTT GAATCTCAGA 
GGAAACAATT TAATGAGTAT AGATTTTCTC ACCGACCCAA ACCTTAAACA ATTAACAACA 
TTTTATGTCA ATAAAAACAG TATAACCACC ATCCCACTTG ACATTCTCCA AAAGTTGCCC 
ATGAACCTTT CAGAGTTTGA TTTGTCTTTT AACCCAATTG ATTGCTCCTG CTCTCAGACT 
GATTTTATGT TGTGGATTAT CAATAATCAG AGAGTTTTGA AACAGCCAGA AAATATTTTG 
TGCAAAACTA TTTCACCAAA CTCAGATTTT AGAGTAACAG ACTTTGACAT TGACCACTGT 
GTCTACAAGA AAAAACTCAT AATTGCTTTA TTGGTATTCT GTGTAGTGTT TATAGTTGTG 
TTATCAATCT TGGTTTACAG GTTTCAATTT TATTTGCGTT ATTGTTGGAT TTTACTAAGA 
GGCTACAGAT CACCTGGACA GCAAGAATGT TCTTATGACG CATTTGTGAT ATTCTCCAGC 
TATGATGAAG CTTGGGTCAT GAATGAACTT ATGGAGAATC TGGAGAACGG TGTGCCACCT 
ATTCAGCTTT GCCTTCACAT GCGGGACTTT CAAGCCGGGA AGTCAATCGC CTCCAACATT 
ATAGATGAAG GAATAATGGG CAGCCGTAAG ATCATTGTGG TCGTGTCTCA ACACTTCATT 
GATAGTGCCT GGTGTCGTTT TGAGTTTGAA TTAGCTCAGT CTCGGTTTGT GGTGGAACGC 
AATGCCAATA TCATCATCAT TATTCTGGAA GATGTTGCGG AGAGGAAAAC TAAGAAAGTG 
CTTGGTCTTC ATAAGCATCT GAAGAAGAAC ACATACCTGA AGTGGAGCAG AGACCCTTTG 
AGCAACATGA GATTCTGGAT ACGACTCAGG AAAGCAATTG TTGCTACATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001315534.1
CDS	11..2461
Translation	MNFFTISAFIIYFPIGAGQSCTEIIENLHYSCMGRNLSYIPSRIPSSVQTLDFSFNDLKWLKKTVFPVFTFLRVLDLSRCHIRQIENDAFYNVKNLTTLFLTGNPIIYFAPGCLNTLYNLQRLVLVDIGLESLQLNINNLTKLQELNVGTNYIQSMTLPPFMSTFKDFSLLDLHANNISIIRTNHTVVLREIGKNMTLILSRNPLLHIEPGSFKGVHLVELDIRSTFVSFASKKQGLNGLHGLNVTRLMFGMYKDDPKLYPSDLDYFDGLCSIHFYEAYYYMKERLDWKMNIFRCMINATVVVVKGGVIRVIGYVPFHKIKELYLINTQLYTVPGKQLSHIRTLEKFVFTHNSATQVEKFLDMPKLQYVDLNSNQITLQSCCIDVLSGTPQIRYLNLSLNPQISLDKGGFEGLESLEILDFHHTKLLGIGSFTLLSNLKNLRYLDISYSSVTFVNVYCFYGLSSLKVLKMAGNSFQGDVANYLFNNLTFLEHLDISYCHVIEIHLTSFKNLQRLRHLNLRGNNLMSIDFLTDPNLKQLTTFYVNKNSITTIPLDILQKLPMNLSEFDLSFNPIDCSCSQTDFMLWIINNQRVLKQPENILCKTISPNSDFRVTDFDIDHCVYKKKLIIALLVFCVVFIVVLSILVYRFQFYLRYCWILLRGYRSPGQQECSYDAFVIFSSYDEAWVMNELMENLENGVPPIQLCLHMRDFQAGKSIASNIIDEGIMGSRKIIVVVSQHFIDSAWCRFEFELAQSRFVVERNANIIIIILEDVAERKTKKVLGLHKHLKKNTYLKWSRDPLSNMRFWIRLRKAIVAT

Target ORF information:

RefSeq Version	NM_001328605.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio toll-like receptor 4a, like (tlr4al), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001328605.1

ORF Insert Sequence:

ATGAATTTCT TTACTATAAG TGCTTTCATA ATATATTTTC CAATAGGTGC TGGACAATCA 
TGCACAGAAA TTATTGAAAA TCTTCATTAT TCATGCATGG GAAGAAACCT AAGCTACATA 
CCATCCAGAA TTCCTTCCTC AGTTCAAACT CTTGATTTTA GTTTTAATGA CCTGAAATGG 
TTAAAGAAAA CTGTATTCCC AGTTTTCACT TTTCTGAGAG TTCTTGATCT GTCAAGATGC 
CACATCAGAC AGATTGAAAA CGATGCTTTC TACAATGTGA AGAATTTGAC TACTTTGTTC 
CTTACTGGAA ACCCTATTAT ATATTTTGCT CCTGGATGCT TGAATACTTT ATATAATCTG 
CAAAGGCTAG TTCTTGTGGA TATTGGTCTT GAATCCTTAC AGCTTAATAT TAATAACCTT 
ACCAAGCTAC AGGAACTCAA TGTTGGAACA AATTACATCC AGTCTATGAC TCTTCCTCCA 
TTCATGAGCA CCTTCAAAGA CTTCAGTTTA CTTGATCTAC ATGCCAACAA TATATCCATC 
ATCAGAACTA ATCACACCGT TGTGCTTCGA GAGATTGGAA AAAACATGAC ATTGATTCTC 
TCTAGGAATC CATTACTACA CATTGAACCA GGGTCTTTTA AAGGGGTTCA TCTTGTAGAG 
CTGGACATCC GATCCACATT TGTTTCGTTT GCTTCAAAGA AACAGGGTCT AAATGGTCTG 
CATGGCCTTA ATGTCACAAG GCTGATGTTT GGAATGTATA AAGATGATCC CAAACTTTAC 
CCATCAGATC TAGACTATTT CGATGGTCTT TGCTCTATTC ATTTTTATGA GGCATATTAT 
TACATGAAGG AAAGACTTGA CTGGAAAATG AATATCTTTC GCTGTATGAT TAATGCCACA 
GTTGTAGTTG TTAAGGGTGG TGTAATTCGT GTCATTGGGT ATGTGCCTTT TCATAAAATC 
AAGGAGCTTT ACTTGATTAA CACTCAGTTA TATACTGTGC CAGGTAAACA ACTTTCACAC 
ATTCGTACTT TAGAAAAATT TGTATTTACA CACAACAGTG CAACTCAAGT TGAAAAATTC 
TTAGACATGC CGAAACTTCA GTATGTGGAT CTTAATTCAA ACCAAATTAC TCTACAATCA 
TGCTGCATAG ATGTTTTATC TGGTACTCCT CAAATCAGAT ATTTAAATTT GAGCTTAAAT 
CCACAAATTT CTCTTGATAA AGGAGGATTT GAAGGACTTG AATCCCTAGA AATTTTAGAT 
TTTCATCATA CAAAGCTTTT AGGTATAGGA TCTTTTACAC TTTTGTCTAA TTTAAAAAAT 
CTGAGGTATC TGGATATTTC TTATTCAAGC GTAACCTTTG TTAACGTATA TTGCTTTTAT 
GGACTGAGCA GTCTTAAAGT TCTCAAGATG GCTGGCAATA GTTTTCAAGG TGATGTAGCA 
AATTATTTAT TTAACAATCT TACATTTTTA GAGCACCTTG ATATTTCATA CTGTCATGTG 
ATAGAAATAC ATTTAACGTC ATTTAAAAAC CTTCAAAGAC TTAGACATTT GAATCTCAGA 
GGAAACAATT TAATGAGTAT AGATTTTCTC ACCGACCCAA ACCTTAAACA ATTAACAACA 
TTTTATGTCA ATAAAAACAG TATAACCACC ATCCCACTTG ACATTCTCCA AAAGTTGCCC 
ATGAACCTTT CAGAGTTTGA TTTGTCTTTT AACCCAATTG ATTGCTCCTG CTCTCAGACT 
GATTTTATGT TGTGGATTAT CAATAATCAG AGAGTTTTGA AACAGCCAGA AAATATTTTG 
TGCAAAACTA TTTCACCAAA CTCAGATTTT AGAGTAACAG ACTTTGACAT TGACCACTGT 
GTCTACAAGA AAAAACTCAT AATTGCTTTA TTGGTATTCT GTGTAGTGTT TATAGTTGTG 
TTATCAATCT TGGTTTACAG GTTTCAATTT TATTTGCGTT ATTGTTGGAT TTTACTAAGA 
GGCTACAGAT CACCTGGACA GCAAGAATGT TCTTATGACG CATTTGTGAT ATTCTCCAGC 
TATGATGAAG CTTGGGTCAT GAATGAACTT ATGGAGAATC TGGAGAACGG TGTGCCACCT 
ATTCAGCTTT GCCTTCACAT GCGGGACTTT CAAGCCGGGA AGTCAATCGC CTCCAACATT 
ATAGATGAAG GAATAATGGG CAGCCGTAAG ATCATTGTGG TCGTGTCTCA ACACTTCATT 
GATAGTGCCT GGTGTCGTTT TGAGTTTGAA TTAGCTCAGT CTCGGTTTGT GGTGGAACGC 
AATGCCAATA TCATCATCAT TATTCTGGAA GATGTTGCGG AGAGGAAAAC TAAGAAAGTG 
CTTGGTCTTC ATAAGCATCT GAAGAAGAAC ACATACCTGA AGTGGAGCAG AGACCCTTTG 
AGCAACATGA GATTCTGGAT ACGACTCAGG AAAGCAATTG TTGCTACATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae.
Chemosphere225820-828(2019 Jun)
Icoglu Aksakal F,Ciltas A,Simsek Ozek N

Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos.
Fish & shellfish immunology86549-558(2019 Mar)
Xiong G,Zou L,Deng Y,Meng Y,Liao X,Lu H

High-Fat Diet Consumption Induces Microbiota Dysbiosis and Intestinal Inflammation in Zebrafish.
Microbial ecology76(4)1089-1101(2018 Nov)
Arias-Jayo N,Abecia L,Alonso-Sáez L,Ramirez-Garcia A,Rodriguez A,Pardo MA

Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs).
Journal of hazardous materials357146-158(2018 09)
Deng S,Jia PP,Zhang JH,Junaid M,Niu A,Ma YB,Fu A,Pei DS

β-Glucan-Producing
Frontiers in microbiology91684(2018)
Pérez-Ramos A,Mohedano ML,Pardo MÁ,López P

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tlr4al cDNA ORF clone, Danio rerio(zebrafish)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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