Khdrbs3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Khdrbs3
Entrez Gene ID	64015
Full Name	KH RNA binding domain containing, signal transduction associated 3
Synonyms	Etle,Slm2
General protein information	Preferred Names KH RNA binding domain containing, signal transduction associated 3 Names KH domain-containing, RNA-binding, signal transduction-associated protein 3 KH domain containing, RNA binding, signal transduction associated 3 SLM-2 etoile, Sam68-like protein SLM-2 rSLM-2 sam68-like mammalian protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q34
Summary	mediates the selection of alternative splice sites; may provide a link between signal transduction pathways and pre-mRNA processing [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022249.1	NP_071585.1	KH domain-containing, RNA-binding, signal transduction-associated protein 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	KHDRBS3	NP_006549.1
Macaca mulatta (Rhesus monkey)	LOC705288	XP_001093657.2
Rattus norvegicus (Norway rat)	Khdrbs3	NP_071585.1
Bos taurus (cattle)	KHDRBS3	NP_001076981.1
Drosophila melanogaster (fruit fly)	qkr58E-1	NP_523809.2
Canis lupus familiaris (dog)	KHDRBS3	XP_848348.2
Gallus gallus (chicken)	KHDRBS3	XP_001231272.1
Drosophila melanogaster (fruit fly)	qkr54B	NP_001261050.1
Danio rerio (zebrafish)	khdrbs3	XP_005172612.1
Xenopus tropicalis (tropical clawed frog)	khdrbs3	XP_002932263.1
Pan troglodytes (chimpanzee)	KHDRBS3	XP_519974.3
Mus musculus (house mouse)	Khdrbs3	NP_034288.2

Gene Ontology
Bibliography

Related articles in PubMed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanhäusser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.
Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S, Scheiffele P
Cell147(7)1601-14(2011 Dec)

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins.
Ray D, Kazan H, Chan ET, Peña Castillo L, Chaudhry S, Talukder S, Blencowe BJ, Morris Q, Hughes TR
Nature biotechnology27(7)667-70(2009 Jul)

Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA.
Heinrich B, Zhang Z, Raitskin O, Hiller M, Benderska N, Hartmann AM, Bracco L, Elliott D, Ben-Ari S, Soreq H, Sperling J, Sperling R, Stamm S
The Journal of biological chemistry284(21)14303-15(2009 May)

p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1.
Stoss O, Novoyatleva T, Gencheva M, Olbrich M, Benderska N, Stamm S
Molecular and cellular neurosciences27(1)8-21(2004 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Khdrbs3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Khdrbs3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05535	NM_022249.1 Latest version!	Rattus norvegicus KH RNA binding domain containing, signal transduction associated 3 (Khdrbs3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Khdrbs3 ( NM_022249.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071585.1 Rattus norvegicus KH RNA binding domain containing, signal transduction associated 3 (Khdrbs3), mRNA.

Price & Availability↑

CloneID	ORa05535
Clone ID Related Accession (Same CDS sequence)	NM_022249.1
Accession Version	NM_022249.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	KH domain-containing, RNA-binding, signal transduction-associated protein 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF152547.1. ##Evidence-Data-START## Transcript exon combination :: AF152547.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGA AGTACCTGCC GGAGCTGATG GCGGAGAAGG ACTCTCTGGA CCCCTCCTTC 
ACGCACGCCC TGCGCTTGGT GAACCGAGAA ATAGAAAAGT TTCAGAAGGG AGAAGCCAAG 
GATGAAGAGA AGTACATTGA TGTGGTGATA AACAAGAACA TGAAGCTGGG ACAGAAAGTG 
TTGATTCCTG TAAAGCAGTT TCCCAAGTTC AACTTTGTGG GGAAGCTTTT GGGTCCACGT 
GGCAATTCCC TGAAGCGCTT ACAAGAAGAA ACGTTGACAA AAATGTCCAT CCTTGGCAAA 
GGTTCCATGA GAGACAAGGC AAAGGAGGAG GAGCTGAGGA AAAGTGGAGA AGCGAAGTAC 
TTTCACCTCA ATGACGACCT GCACGTGCTC ATTGAAGTGT TCGCGCCCCC AGCGGAAGCT 
TATGCCCGGA TGGGGCATGC CTTGGAAGAC ATTAAGAAGT TCCTGATCCC TGACTATAAT 
GATGAAATCA GGCAAGCACA GCTCCAGGAA TTAACTTATT TGAATGGAGG TTCAGAAAAT 
GCAGATGTCC CAGTGGTTCG AGGGAAATCA ACTTTGCGTA CGAGAGGTGT AACGACACCA 
GCAATAACCA GGGGAAGAGG AGGAGTCACA GCCAGGCCTG TTGCAGTTGG GGTACCACGT 
GGGACACCGA CTCCCCGAGG AGTCCTTTCC ACCCGAGGGC CAGTGAGCCG GGGAAGAGGA 
CTTCTCACTC CCAGAGCAAG AGGTGTCCCC CCAACTGGAT ACAGACCTCC ACCGCCACCC 
CCAACACAGG AGACCTATGG AGAGTATGAC TATGACGATG GGTACAGTAC AGCATATGAT 
GACCAGAGCT ACGACTCCTA TGACAACAGC TACAGCACCC CAGCACAAAG CGGAGCGGAT 
TACTATGATT ACGGGCATGG ACTCGGCGAG GAGGCTTATG ATTCCTATGG GCAAGAGGAC 
TGGACTAACT CAAGACATAA GGCTCCTTCG GCGAGGACAG CGAAGGGCGT CTACAGAGAG 
CAGCCATATG GCAGATACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071585.1
CDS	121..1161
Translation	MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEAKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEDIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYSTAYDDQSYDSYDNSYSTPAQSGADYYDYGHGLGEEAYDSYGQEDWTNSRHKAPSARTAKGVYREQPYGRY

Target ORF information:

RefSeq Version	NM_022249.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus KH RNA binding domain containing, signal transduction associated 3 (Khdrbs3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022249.1

ORF Insert Sequence:

ATGGAGGAGA AGTACCTGCC GGAGCTGATG GCGGAGAAGG ACTCTCTGGA CCCCTCCTTC 
ACGCACGCCC TGCGCTTGGT GAACCGAGAA ATAGAAAAGT TTCAGAAGGG AGAAGCCAAG 
GATGAAGAGA AGTACATTGA TGTGGTGATA AACAAGAACA TGAAGCTGGG ACAGAAAGTG 
TTGATTCCTG TAAAGCAGTT TCCCAAGTTC AACTTTGTGG GGAAGCTTTT GGGTCCACGT 
GGCAATTCCC TGAAGCGCTT ACAAGAAGAA ACGTTGACAA AAATGTCCAT CCTTGGCAAA 
GGTTCCATGA GAGACAAGGC AAAGGAGGAG GAGCTGAGGA AAAGTGGAGA AGCGAAGTAC 
TTTCACCTCA ATGACGACCT GCACGTGCTC ATTGAAGTGT TCGCGCCCCC AGCGGAAGCT 
TATGCCCGGA TGGGGCATGC CTTGGAAGAC ATTAAGAAGT TCCTGATCCC TGACTATAAT 
GATGAAATCA GGCAAGCACA GCTCCAGGAA TTAACTTATT TGAATGGAGG TTCAGAAAAT 
GCAGATGTCC CAGTGGTTCG AGGGAAATCA ACTTTGCGTA CGAGAGGTGT AACGACACCA 
GCAATAACCA GGGGAAGAGG AGGAGTCACA GCCAGGCCTG TTGCAGTTGG GGTACCACGT 
GGGACACCGA CTCCCCGAGG AGTCCTTTCC ACCCGAGGGC CAGTGAGCCG GGGAAGAGGA 
CTTCTCACTC CCAGAGCAAG AGGTGTCCCC CCAACTGGAT ACAGACCTCC ACCGCCACCC 
CCAACACAGG AGACCTATGG AGAGTATGAC TATGACGATG GGTACAGTAC AGCATATGAT 
GACCAGAGCT ACGACTCCTA TGACAACAGC TACAGCACCC CAGCACAAAG CGGAGCGGAT 
TACTATGATT ACGGGCATGG ACTCGGCGAG GAGGCTTATG ATTCCTATGG GCAAGAGGAC 
TGGACTAACT CAAGACATAA GGCTCCTTCG GCGAGGACAG CGAAGGGCGT CTACAGAGAG 
CAGCCATATG GCAGATACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.
Cell147(7)1601-14(2011 Dec)
Iijima T,Wu K,Witte H,Hanno-Iijima Y,Glatter T,Richard S,Scheiffele P

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins.
Nature biotechnology27(7)667-70(2009 Jul)
Ray D,Kazan H,Chan ET,Peña Castillo L,Chaudhry S,Talukder S,Blencowe BJ,Morris Q,Hughes TR

Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA.
The Journal of biological chemistry284(21)14303-15(2009 May)
Heinrich B,Zhang Z,Raitskin O,Hiller M,Benderska N,Hartmann AM,Bracco L,Elliott D,Ben-Ari S,Soreq H,Sperling J,Sperling R,Stamm S

p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1.
Molecular and cellular neurosciences27(1)8-21(2004 Sep)
Stoss O,Novoyatleva T,Gencheva M,Olbrich M,Benderska N,Stamm S

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Khdrbs3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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