Ifih1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ifih1
Entrez Gene ID	499801
Full Name	interferon induced with helicase C domain 1
Synonyms	RGD1560496
General protein information	Preferred Names interferon induced with helicase C domain 1 Names interferon-induced helicase C domain-containing protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q21

mRNA and Protein(s)

mRNA	Protein	Name
NM_001109199.1	NP_001102669.1	interferon-induced helicase C domain-containing protein 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC565759	XP_694124.4
Bos taurus (cattle)	IFIH1	XP_002685384.1
Mus musculus (house mouse)	Ifih1	NP_082111.2
Rattus norvegicus (Norway rat)	Ifih1	NP_001102669.1
Homo sapiens (human)	IFIH1	NP_071451.2
Pan troglodytes (chimpanzee)	IFIH1	XP_003309348.1
Macaca mulatta (Rhesus monkey)	IFIH1	NP_001040588.1
Canis lupus familiaris (dog)	IFIH1	XP_545493.2
Gallus gallus (chicken)	IFIH1	NP_001180567.1
Xenopus tropicalis (tropical clawed frog)	ifih1	XP_002933320.2

Gene Ontology
Bibliography

Related articles in PubMed

RIOK3-mediated phosphorylation of MDA5 interferes with its assembly and attenuates the innate immune response.
Takashima K, Oshiumi H, Takaki H, Matsumoto M, Seya T
Cell reports11(2)192-200(2015 Apr)

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition.
Peisley A, Lin C, Wu B, Orme-Johnson M, Liu M, Walz T, Hur S
Proceedings of the National Academy of Sciences of the United States of America108(52)21010-5(2011 Dec)

DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells.
Zhang Z, Yuan B, Lu N, Facchinetti V, Liu YJ
Journal of immunology (Baltimore, Md. : 1950)187(9)4501-8(2011 Nov)

A diverse range of gene products are effectors of the type I interferon antiviral response.
Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, Bieniasz P, Rice CM
Nature472(7344)481-5(2011 Apr)

MDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signaling.
Fu J, Xiong Y, Xu Y, Cheng G, Tang H
Molecular immunology48(4)415-22(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ifih1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ifih1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09307	NM_001109199.1 Latest version!	Rattus norvegicus interferon induced with helicase C domain 1 (Ifih1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ifih1 ( NM_001109199.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102669.1 Rattus norvegicus interferon induced with helicase C domain 1 (Ifih1), mRNA.

Price & Availability↑

CloneID	ORa09307
Clone ID Related Accession (Same CDS sequence)	NM_001109199.1
Accession Version	NM_001109199.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3084bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1507305600000
Organism	Rattus norvegicus(Norway rat)
Product	interferon-induced helicase C domain-containing protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_575141.2, XM_001055482.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCGACCG TCTGTTCTGC AGAGGACAGC TTCAGGAATC TCATCTCAAT CTTCAGGCCC 
AGGGTGAAAA TGAACATTCA GGTGGAGCCG GTGCTGGACT ACCTCGTCTT TCTGCCGGCA 
GAAACCAAAG AGCAGATTCT TAGAAAGGTC ACCACCTGTG GTAACACCAG CGCCGCAGAA 
CTGCTGCTGA GCACCTTGGA GCAGGGACAG TGGCCGCTGG GATGGACGCA GATGTTCGTC 
GAGGCCCTGG AGCACAGTGG CAACCCTCTA GCCGCGCGCT ATGTCAAACC CAGTCTTACT 
GATCTGCCCT CTCCTTCCTC TGAGACCGCC CATGATGAGT GTCTCCACTT GCTGAACCTC 
CTCCAGCCCA CTTTAGTGGG CAAGCTCCTG ATTAATGATG TCTTGGATAC TTGCTCCGAG 
AAGGGACTGG TGACAGTCGA GGACAGAAAT CGGATTTCTG CTGCGGGAAA TAGTGGGAAT 
GAGTCAGGAG TAAGAGAACT GCTGAGAAGG ATAGTGCAGA AAGAAAACTG GTTTTCTACC 
TTCCTGGATG TTCTTCGCCA AACTGGAAAC GATGCGCTAG TCCAAGAGCT AACAGGTGTG 
AGCTGCCCAG AAGAGAGCAC AGACTTGGAT AACGCATCTC ACAAAGACAG GCCTGCAGCT 
AACGAGCCCC TTCTGCCCGC CATCGATGCA TTAAGTCTGG AGACAGAGGC CTGGACCATA 
GAGGACACCT CACCAGAGGC TTCCTTTGCA GATTCTTCTG TGACCACAGA ATCAGACACA 
AGTTTGGCAG AAGGAAGTGT CAGCTGCTTC GATGAAAGTC TTGGACATAA CAGCAACATG 
GGCAGGGATT CAGGCACCAT GGGAAGTGAT TCAGATGAAG ATACCATCAT GGGGACAAAA 
AGAGCATCCC CCAAGCCAGA ACTGCAGCTC AGGCCTTACC AAATGGAAGT GGCCCAGCCT 
GCCCTGGATG GGAAGAATAT TATTATCTGC CTCCCCACGG GGAGCGGGAA AACCAGAGTG 
GCAGTTTACA TCACCAAAGA TCACTTAGAC AAGAAGAAGC AGGCGTGTGA ATCCGGGAAG 
GTTATCGTCC TTGTCAATAA GGTAATGTTA GCAGAACAAC TTTTCCGCAA AGAGTTCAAC 
CCGTTCTTGA AGAAATGGTA TCGCATTATT GGATTAAGCG GCGATACCCA GCTGAAAATA 
TCTTTTCCAG AAGTTGTCAA ATCTTACGAT GTTATTATCA GCACAGCTCA AATCCTTGAA 
AACTCCCTCT TAAATCTGGA GAGTGGGGAA GATGATGGTG TGCAGCTGTC AGACTTTTCC 
CTTATTATCA TTGACGAGTG TCATCATACC AACAAGGAGG CAGTCTATAA CAACATCATG 
AGACGGTATT TGAAGCAGAA GTTGAAAAAC CATAAACTCA AGAAACAAAA CAAACCAACA 
ATTCACCTGC CTCAGATACT AGGACTGACA GCTTCACCGG GTGTTGGAGC AGCCAAAAAG 
CAATCTGAGG CTGAAAAACA TATTTTAAAT ATATGTGCCA ATCTCGATGC CTTTACCATT 
AAAACAGTGA AAGAGAATCT CAGTCAACTC AAACACCAAA TAAAGGAACC ATGCAAGAAG 
TTTGTGATTG CTGATGACAC CAGAGAGAAT CCATTTAAAG AGAAACTTCT AGAAATTATG 
GCAAGCATTC AAACTTACTG CCAAAAGAGT CCATTGTCAG ATTTTGGAAC CCAACATTAT 
GAGCAGTGGG CTATTCAAAT GGAAAAAAAA GCTGCTAAAG ACGGAAATCG CAGAGATCGT 
GTCTGTGCAG AACATTTGAG GAAGTACAAC GAAGCCCTAC AAATCAATGA CACGATCCGA 
ATGATTGACG CGTACAGCCA CCTGGAAACG TTCTACACCG ACGAGAAAGA AAAGAAGTTT 
GCAGCCCTCA ATGACAGCGA TGAGAGTGAC GACGACGAGG CCAGCAGTTG CCATGACCAA 
CTTAAGGGCA ATGTAAAGAA ATCTTTGAAA CTGGACGAAA CGGATGAATT TCTCATGAAT 
TTGTTCTTCG ATAACAAGAA AATGTTGAAA AAACTAGCTG AAAACCCAAA GTACGAGAAC 
GAAAAACTCA TTAAATTAAG AAACACGATC CTGGAACAGT TCACAAGGTC TGAGGAGTCC 
TCCCGAGGAA TTATTTTCAC AAAAACGCGG CAGAGCACCT ATGCGCTTTC CCAGTGGATT 
ATGGAGAATG AAAAGTTTGC GGAAGTTGGA GTCAAAGCGC ATCACCTGAT TGGCGCGGGA 
CACAGCAGCG AGGTCAAGCC CATGACTCAG ACTGAACAAA AAGAAGTCAT TAGTAAATTT 
CGCACTGGGG AAATAAATCT GCTTATCGCT ACTACGGTGG CAGAGGAAGG CCTGGATATC 
AAAGAATGCA ATATCGTTAT CCGGTATGGC CTTGTCACGA ACGAGATAGC CATGGTCCAG 
GCCCGGGGTC GAGCTAGAGC CGATGAGAGC ACCTACGTCC TGGTTACCAG CAGTGGCTCG 
GGAGTTACTG AACGGGAGAT TGTTAATGAT TTCCGAGAGA AGATGATGTA TAAAGCTATT 
AACCGTGTTC AAAATATGAA ACCAGAGGAG TATGCACATA AGATTTTGGA ATTACAAGTG 
CAAAGTATCT TGGAAAAGAA GATGAAAGTC AAGAGAAGTA TTGCGAGGCA GTACAACAGC 
GATCCATCGT TAATAACACT TCTCTGCAAA AACTGTAGTA CGCTGGTCTG CTCAGGAGAA 
AACATCCACG TAATTGAGAA GATGCATCAT GTCAACATGA CACCAGAGTT CAAGGGACTC 
TACATTGTGA GAGAGAACAA AGCACTACAA ATGAAATTTG CTGATTATCA GACAAATGGA 
GAGATTATCT GCAAATGTGG CCAAGCTTGG GGAACAATGA TGGTGCACAA AGGTTTAGAT 
TTGCCTTGTC TTAAAATAAG GAATTTTGTA GTCAATTTCA AAAATAACTC ATCAAAGAAA 
CAGTACAAGA AGTGGGTGGA ATTGCCTATC AGATTTCCTG ATCTCGATTG CTCAGAGTAC 
TGCTTGTATA GTGATGAAGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102669.1
CDS	222..3305
Translation	MSTVCSAEDSFRNLISIFRPRVKMNIQVEPVLDYLVFLPAETKEQILRKVTTCGNTSAAELLLSTLEQGQWPLGWTQMFVEALEHSGNPLAARYVKPSLTDLPSPSSETAHDECLHLLNLLQPTLVGKLLINDVLDTCSEKGLVTVEDRNRISAAGNSGNESGVRELLRRIVQKENWFSTFLDVLRQTGNDALVQELTGVSCPEESTDLDNASHKDRPAANEPLLPAIDALSLETEAWTIEDTSPEASFADSSVTTESDTSLAEGSVSCFDESLGHNSNMGRDSGTMGSDSDEDTIMGTKRASPKPELQLRPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQACESGKVIVLVNKVMLAEQLFRKEFNPFLKKWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILENSLLNLESGEDDGVQLSDFSLIIIDECHHTNKEAVYNNIMRRYLKQKLKNHKLKKQNKPTIHLPQILGLTASPGVGAAKKQSEAEKHILNICANLDAFTIKTVKENLSQLKHQIKEPCKKFVIADDTRENPFKEKLLEIMASIQTYCQKSPLSDFGTQHYEQWAIQMEKKAAKDGNRRDRVCAEHLRKYNEALQINDTIRMIDAYSHLETFYTDEKEKKFAALNDSDESDDDEASSCHDQLKGNVKKSLKLDETDEFLMNLFFDNKKMLKKLAENPKYENEKLIKLRNTILEQFTRSEESSRGIIFTKTRQSTYALSQWIMENEKFAEVGVKAHHLIGAGHSSEVKPMTQTEQKEVISKFRTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVTSSGSGVTEREIVNDFREKMMYKAINRVQNMKPEEYAHKILELQVQSILEKKMKVKRSIARQYNSDPSLITLLCKNCSTLVCSGENIHVIEKMHHVNMTPEFKGLYIVRENKALQMKFADYQTNGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVNFKNNSSKKQYKKWVELPIRFPDLDCSEYCLYSDED

Target ORF information:

RefSeq Version	NM_001109199.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interferon induced with helicase C domain 1 (Ifih1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109199.1

ORF Insert Sequence:

ATGTCGACCG TCTGTTCTGC AGAGGACAGC TTCAGGAATC TCATCTCAAT CTTCAGGCCC 
AGGGTGAAAA TGAACATTCA GGTGGAGCCG GTGCTGGACT ACCTCGTCTT TCTGCCGGCA 
GAAACCAAAG AGCAGATTCT TAGAAAGGTC ACCACCTGTG GTAACACCAG CGCCGCAGAA 
CTGCTGCTGA GCACCTTGGA GCAGGGACAG TGGCCGCTGG GATGGACGCA GATGTTCGTC 
GAGGCCCTGG AGCACAGTGG CAACCCTCTA GCCGCGCGCT ATGTCAAACC CAGTCTTACT 
GATCTGCCCT CTCCTTCCTC TGAGACCGCC CATGATGAGT GTCTCCACTT GCTGAACCTC 
CTCCAGCCCA CTTTAGTGGG CAAGCTCCTG ATTAATGATG TCTTGGATAC TTGCTCCGAG 
AAGGGACTGG TGACAGTCGA GGACAGAAAT CGGATTTCTG CTGCGGGAAA TAGTGGGAAT 
GAGTCAGGAG TAAGAGAACT GCTGAGAAGG ATAGTGCAGA AAGAAAACTG GTTTTCTACC 
TTCCTGGATG TTCTTCGCCA AACTGGAAAC GATGCGCTAG TCCAAGAGCT AACAGGTGTG 
AGCTGCCCAG AAGAGAGCAC AGACTTGGAT AACGCATCTC ACAAAGACAG GCCTGCAGCT 
AACGAGCCCC TTCTGCCCGC CATCGATGCA TTAAGTCTGG AGACAGAGGC CTGGACCATA 
GAGGACACCT CACCAGAGGC TTCCTTTGCA GATTCTTCTG TGACCACAGA ATCAGACACA 
AGTTTGGCAG AAGGAAGTGT CAGCTGCTTC GATGAAAGTC TTGGACATAA CAGCAACATG 
GGCAGGGATT CAGGCACCAT GGGAAGTGAT TCAGATGAAG ATACCATCAT GGGGACAAAA 
AGAGCATCCC CCAAGCCAGA ACTGCAGCTC AGGCCTTACC AAATGGAAGT GGCCCAGCCT 
GCCCTGGATG GGAAGAATAT TATTATCTGC CTCCCCACGG GGAGCGGGAA AACCAGAGTG 
GCAGTTTACA TCACCAAAGA TCACTTAGAC AAGAAGAAGC AGGCGTGTGA ATCCGGGAAG 
GTTATCGTCC TTGTCAATAA GGTAATGTTA GCAGAACAAC TTTTCCGCAA AGAGTTCAAC 
CCGTTCTTGA AGAAATGGTA TCGCATTATT GGATTAAGCG GCGATACCCA GCTGAAAATA 
TCTTTTCCAG AAGTTGTCAA ATCTTACGAT GTTATTATCA GCACAGCTCA AATCCTTGAA 
AACTCCCTCT TAAATCTGGA GAGTGGGGAA GATGATGGTG TGCAGCTGTC AGACTTTTCC 
CTTATTATCA TTGACGAGTG TCATCATACC AACAAGGAGG CAGTCTATAA CAACATCATG 
AGACGGTATT TGAAGCAGAA GTTGAAAAAC CATAAACTCA AGAAACAAAA CAAACCAACA 
ATTCACCTGC CTCAGATACT AGGACTGACA GCTTCACCGG GTGTTGGAGC AGCCAAAAAG 
CAATCTGAGG CTGAAAAACA TATTTTAAAT ATATGTGCCA ATCTCGATGC CTTTACCATT 
AAAACAGTGA AAGAGAATCT CAGTCAACTC AAACACCAAA TAAAGGAACC ATGCAAGAAG 
TTTGTGATTG CTGATGACAC CAGAGAGAAT CCATTTAAAG AGAAACTTCT AGAAATTATG 
GCAAGCATTC AAACTTACTG CCAAAAGAGT CCATTGTCAG ATTTTGGAAC CCAACATTAT 
GAGCAGTGGG CTATTCAAAT GGAAAAAAAA GCTGCTAAAG ACGGAAATCG CAGAGATCGT 
GTCTGTGCAG AACATTTGAG GAAGTACAAC GAAGCCCTAC AAATCAATGA CACGATCCGA 
ATGATTGACG CGTACAGCCA CCTGGAAACG TTCTACACCG ACGAGAAAGA AAAGAAGTTT 
GCAGCCCTCA ATGACAGCGA TGAGAGTGAC GACGACGAGG CCAGCAGTTG CCATGACCAA 
CTTAAGGGCA ATGTAAAGAA ATCTTTGAAA CTGGACGAAA CGGATGAATT TCTCATGAAT 
TTGTTCTTCG ATAACAAGAA AATGTTGAAA AAACTAGCTG AAAACCCAAA GTACGAGAAC 
GAAAAACTCA TTAAATTAAG AAACACGATC CTGGAACAGT TCACAAGGTC TGAGGAGTCC 
TCCCGAGGAA TTATTTTCAC AAAAACGCGG CAGAGCACCT ATGCGCTTTC CCAGTGGATT 
ATGGAGAATG AAAAGTTTGC GGAAGTTGGA GTCAAAGCGC ATCACCTGAT TGGCGCGGGA 
CACAGCAGCG AGGTCAAGCC CATGACTCAG ACTGAACAAA AAGAAGTCAT TAGTAAATTT 
CGCACTGGGG AAATAAATCT GCTTATCGCT ACTACGGTGG CAGAGGAAGG CCTGGATATC 
AAAGAATGCA ATATCGTTAT CCGGTATGGC CTTGTCACGA ACGAGATAGC CATGGTCCAG 
GCCCGGGGTC GAGCTAGAGC CGATGAGAGC ACCTACGTCC TGGTTACCAG CAGTGGCTCG 
GGAGTTACTG AACGGGAGAT TGTTAATGAT TTCCGAGAGA AGATGATGTA TAAAGCTATT 
AACCGTGTTC AAAATATGAA ACCAGAGGAG TATGCACATA AGATTTTGGA ATTACAAGTG 
CAAAGTATCT TGGAAAAGAA GATGAAAGTC AAGAGAAGTA TTGCGAGGCA GTACAACAGC 
GATCCATCGT TAATAACACT TCTCTGCAAA AACTGTAGTA CGCTGGTCTG CTCAGGAGAA 
AACATCCACG TAATTGAGAA GATGCATCAT GTCAACATGA CACCAGAGTT CAAGGGACTC 
TACATTGTGA GAGAGAACAA AGCACTACAA ATGAAATTTG CTGATTATCA GACAAATGGA 
GAGATTATCT GCAAATGTGG CCAAGCTTGG GGAACAATGA TGGTGCACAA AGGTTTAGAT 
TTGCCTTGTC TTAAAATAAG GAATTTTGTA GTCAATTTCA AAAATAACTC ATCAAAGAAA 
CAGTACAAGA AGTGGGTGGA ATTGCCTATC AGATTTCCTG ATCTCGATTG CTCAGAGTAC 
TGCTTGTATA GTGATGAAGA CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RIOK3-mediated phosphorylation of MDA5 interferes with its assembly and attenuates the innate immune response.
Cell reports11(2)192-200(2015 Apr)
Takashima K,Oshiumi H,Takaki H,Matsumoto M,Seya T

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition.
Proceedings of the National Academy of Sciences of the United States of America108(52)21010-5(2011 Dec)
Peisley A,Lin C,Wu B,Orme-Johnson M,Liu M,Walz T,Hur S

DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)187(9)4501-8(2011 Nov)
Zhang Z,Yuan B,Lu N,Facchinetti V,Liu YJ

A diverse range of gene products are effectors of the type I interferon antiviral response.
Nature472(7344)481-5(2011 Apr)
Schoggins JW,Wilson SJ,Panis M,Murphy MY,Jones CT,Bieniasz P,Rice CM

MDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signaling.
Molecular immunology48(4)415-22(2011 Jan)
Fu J,Xiong Y,Xu Y,Cheng G,Tang H

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Ifih1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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