ifih1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ifih1
Entrez Gene ID	565759
Full Name	interferon induced with helicase C domain 1
Synonyms	MDA5a,MDA5b,si:dkey-81j5.2
General protein information	Preferred Names interferon induced with helicase C domain 1 Names interferon-induced helicase C domain-containing protein 1 mda5 melanoma differentiation-associated protein 5a melanoma differentiation-associated protein 5b
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001308563.1	NP_001295492.1	interferon-induced helicase C domain-containing protein 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC565759	XP_694124.4
Bos taurus (cattle)	IFIH1	XP_002685384.1
Mus musculus (house mouse)	Ifih1	NP_082111.2
Rattus norvegicus (Norway rat)	Ifih1	NP_001102669.1
Homo sapiens (human)	IFIH1	NP_071451.2
Pan troglodytes (chimpanzee)	IFIH1	XP_003309348.1
Macaca mulatta (Rhesus monkey)	IFIH1	NP_001040588.1
Canis lupus familiaris (dog)	IFIH1	XP_545493.2
Gallus gallus (chicken)	IFIH1	NP_001180567.1
Xenopus tropicalis (tropical clawed frog)	ifih1	XP_002933320.2

Gene Ontology
Bibliography

Related articles in PubMed

RNF135 is a positive regulator of IFN expression and involved in RIG-I signaling pathway by targeting RIG-I.
Lai Y, Liang M, Hu, Zeng Z, Lin H, Yi G, Li M, Liu Z
Fish & shellfish immunology86474-479(2019 Mar)

Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome.
Rajshekar S, Yao J, Arnold PK, Payne SG, Zhang Y, Bowman TV, Schmitz RJ, Edwards JR, Goll M
eLife7(2018 11)

Diversification of the functions of proglucagon and glucagon receptor genes in fish.
Irwin DM, Mojsov S
General and comparative endocrinology261148-165(2018 05)

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia.
Danilova N, Wilkes M, Bibikova E, Youn MY, Sakamoto KM, Lin S
Scientific reports8(1)5165(2018 03)

Alternative Splicing Transcripts of Zebrafish LGP2 Gene Differentially Contribute to IFN Antiviral Response.
Zhang QM, Zhao X, Li Z, Wu M, Gui JF, Zhang YB
Journal of immunology (Baltimore, Md. : 1950)200(2)688-703(2018 01)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ifih1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ifih1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa44709	NM_001308563.1 Latest version!	Danio rerio interferon induced with helicase C domain 1 (ifih1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ifih1 ( NM_001308563.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001295492.1 Danio rerio interferon induced with helicase C domain 1 (ifih1), mRNA.

Price & Availability↑

CloneID	ODa44709
Clone ID Related Accession (Same CDS sequence)	NM_001308563.1
Accession Version	NM_001308563.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2994bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1563552000000
Organism	Danio rerio(zebrafish)
Product	interferon-induced helicase C domain-containing protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JX462556.1. On May 13, 2015 this sequence version replaced XM_689032.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: JX462556.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGATCCAA ACATGAGCAG CGATCAAGAC ACCGAGACTC GACACATTCT GGACTGTTTC 
AGAGACAGAC TCAAGCGGCT TATTCAGGTC GAGCCTCTGC TGGATCTGCT GGATTTCCTT 
GAACCGGACA AAAAAGAGCG AATAAAAGCC AAAGTGGCCT CGGAGGGGAA TATAAATGCC 
GTTTCTTTGC TTATCAATGA GATTATGCGC GCAGAGCTCC AGCAGGGGTG GTCGAGGACT 
CTGGTGACCG CGCTGGAGAC CGTCGGGTGC GGGCACGCCG CGCGGTATGT GCGCAACAGG 
CCGCCGGAGC CAGATGAAGA AGCCGAACAC GACAGCTGTG TGCGGCTTAT AGACCTGCTG 
CATCTCAGCC TGGTCAACAT GAAGACCCGG GACGTGTGTG TGCAGTGTGT GACTCTGGGG 
CTGCTAACGC AAGAGGACCA GGAGAATATT ATGACAGCCA CCGGGAACAA CGGAAATATA 
AATGGTGCTC GTCTGCTCCT CAAAAGGCTG GTGAAAAACG AAGCTGGCTG GTTTTCTAAA 
TTCCTTCAGG CTCTGGAGGA CACGGAGCAC CGTGACCTGA TGCGCGAGCT GCGAGGAGAG 
CCGTGCGAGG GGGACGAGGG GATGTCCGTG GACTCGTCGG ATGCTCAGGC TGAAGTGAAG 
GACACCGGTG CAGTCAGAAG AAACTCCATG TCTTCTCCTC CTCCGTCTTT CACCCCCAAC 
AGCTCTCTTC AGTCAGAGGA TCTGGACGAC AGTGTGGACA GCAGCGTTCT GGGTGTGGAG 
GCTGGAAATC GAGGGGTGGA GATGTATGAA GACGGTGAAG AAAAGGAGGA GAAAGATCTC 
AAAGAAGATG AGGACGATGA TTCATCAGCA AGTAAGAGGG AAATTAAACT GCGGGACTAT 
CAGATGGAGG TGGCCAGACC TGCTCTGGAG GAGAAGAACA TCATTGTCTG CCTGCCCACC 
GGATCCGGGA AGACCAGGGT CGCAGTGTTT ATCACCAAAG AGCATTTGGA GAGGGAGCAG 
CGGATGGGGC AGAAGGGGAA AGTGGTCGTC CTGGTCAACA AGGTCCCGCT GGTTGAGCAG 
CATTACAAGG CCGAGTTCGG GAGGTTTTTA AAGCACCAAT ACTCAGTGGA GCGGGTCAGC 
GGTGCCTCAC AGCTCAAAAT CTCCTTCCCA CAAATCATAG AGAAAAATGA CATCATCATC 
TGCACGGCGC AGATTCTGGA AAACTCTTTA GCCAAAGCCA AAAACGGCGA CGAGGACGGG 
ATCGAATTAT CACAGTTCAC CCTGATGGTT ATTGATGAGT GCCACCACAC GAAGAAGGGC 
GGTGTGTATA ACCACATCAT GATTCGCTAC CTGGAACAGA AGAATAGGAA CCAGCTGCTG 
AAGAAGCAGG ACAAAACTTT AGTTCCCATC CCTCAGATCC TGGGTCTGAC GGCCTCACCT 
GGTGTGGGAG GAGCGGTCAG CCAGCAGATG GCGGAGGAGC ATATTCTCCA GATCTGCGCA 
AACTTGGATG CCTTCACAAT CAAAACAAAG ACTTTCGAAG AAGAAGAGGC CAAAACACCA 
TTCAAGAGGA TTGCGAAAGC AGAAGAGAGG AAAGAGGACC CATTTGGAGA TGTGATCAAG 
AAGATCATGG ATGAAATCCA CACACATGCT GACCTGCAGC CCCTTTGTGA GCCCGGCACA 
CAGAACTATG AACAGTGGGT CGTGCAGAAA GGGCAGAACG CTGCTAAAGA GGAGAATCAG 
AATGTTCGCG TGTGTGCCGA ACACCTCCGC CAATACAATG AGGCTCTTCA TCAGAGCAAC 
ACCATTCGAA TGTCTGACGC TTTCCGGTTC CTGGACAAAT ATCACAATGA AGAGCTCAAG 
ACCAAATCTA GCCCTGACGA GGAAGGCAAC ATTACAATCA CGGACACAGA GAGATTCCTC 
TTCACTTTGT TCAAAGACAA AAAAGCGAAG CTGCAGGAGC TGATGGGAAA GCCGCAGTAT 
GAAAATAATA ATCTGGCCCA GCTGAAAACC ATCATCCTGA AGGAATTCTG CACCAGGGAG 
AAGGCGAGAG GCATCATATT CACCCAGACC CGCCTCAGCG CCATCGCTCT CTGCCAGTGG 
ATTGAAGAAA ACCCCAAGTT TGATGAAGTG GGAGTCCAAG CCAGTTATCT GATCGGCGGA 
GGAGACCAGA GCGTGGTGAA ACCCATGACC GCTGCGGAGC AGAAGGATGT GCTGAAAAGG 
TTTCGTACAG GCGAGATCAA TCTGCTAATA GCCACCACTG TTGCAGAAGA GGGTTTGGAC 
ATCGCTGAAT GTAATGTGGT CATTCGCTAT TGCCTGGTGA CCAACGAGGT CGCCATGATT 
CAGGCCCGCG GTCGAGGAAG AGCTGAGGAC AGTAGCTACA CGCTGGTGGC GGAGGCCGGG 
TCTGGAGTGG CGGAGAGAGA GAGTGTTAAC GAATACAGAG AGAAAATGAT GAGCAAAGCC 
ATCGCTAAAG TCTGCAAAAT GAACCGAGCT GACTACGAAA AGAAAATCAT GGAGTTTCAG 
ATCCAGGCCA TAATGGAGGA GAAAGTCAAG ACCAAAAAGA AACAGCAGAA GGGAATGATG 
AAGGAGGCGC CATCTAAAAT CCGCCTGAGC TGCAGGCAGT GCAGTGTGTT TGTGTGCTCT 
GGAGAAGACA TCGAGATCAT CGAGAAGATG CACCATGTCA ACGTTACCAA ACAGTTCAGA 
AAGCTGTTCA TAGTCCGAGA GAATGCGTCA CTACAGGAGC GACTCTTGGA CTACGAGACC 
AACGGAGTCA TTGCGTGCAA AAAATGTGGA CAGCAATGGG GTTCAATGAT GCTGTACAGA 
AGCACTGAAT GTCCCTGCCT TCATATCAAG AACTTTGTAG TCACATACGG CTCCAAGAAG 
AAGACGTTCA GCAAATGGAG AGAGCTGTCC ATAAGCTTCC CTGCATTTGA CTACACCCAG 
CACGCCGATC TCCTTGTTGA GGATTCAGAG GATGAAGATA TGGACACTAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295492.1
CDS	61..3054
Translation	MDPNMSSDQDTETRHILDCFRDRLKRLIQVEPLLDLLDFLEPDKKERIKAKVASEGNINAVSLLINEIMRAELQQGWSRTLVTALETVGCGHAARYVRNRPPEPDEEAEHDSCVRLIDLLHLSLVNMKTRDVCVQCVTLGLLTQEDQENIMTATGNNGNINGARLLLKRLVKNEAGWFSKFLQALEDTEHRDLMRELRGEPCEGDEGMSVDSSDAQAEVKDTGAVRRNSMSSPPPSFTPNSSLQSEDLDDSVDSSVLGVEAGNRGVEMYEDGEEKEEKDLKEDEDDDSSASKREIKLRDYQMEVARPALEEKNIIVCLPTGSGKTRVAVFITKEHLEREQRMGQKGKVVVLVNKVPLVEQHYKAEFGRFLKHQYSVERVSGASQLKISFPQIIEKNDIIICTAQILENSLAKAKNGDEDGIELSQFTLMVIDECHHTKKGGVYNHIMIRYLEQKNRNQLLKKQDKTLVPIPQILGLTASPGVGGAVSQQMAEEHILQICANLDAFTIKTKTFEEEEAKTPFKRIAKAEERKEDPFGDVIKKIMDEIHTHADLQPLCEPGTQNYEQWVVQKGQNAAKEENQNVRVCAEHLRQYNEALHQSNTIRMSDAFRFLDKYHNEELKTKSSPDEEGNITITDTERFLFTLFKDKKAKLQELMGKPQYENNNLAQLKTIILKEFCTREKARGIIFTQTRLSAIALCQWIEENPKFDEVGVQASYLIGGGDQSVVKPMTAAEQKDVLKRFRTGEINLLIATTVAEEGLDIAECNVVIRYCLVTNEVAMIQARGRGRAEDSSYTLVAEAGSGVAERESVNEYREKMMSKAIAKVCKMNRADYEKKIMEFQIQAIMEEKVKTKKKQQKGMMKEAPSKIRLSCRQCSVFVCSGEDIEIIEKMHHVNVTKQFRKLFIVRENASLQERLLDYETNGVIACKKCGQQWGSMMLYRSTECPCLHIKNFVVTYGSKKKTFSKWRELSISFPAFDYTQHADLLVEDSEDEDMDTN

Target ORF information:

RefSeq Version	NM_001308563.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio interferon induced with helicase C domain 1 (ifih1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308563.1

ORF Insert Sequence:

ATGGATCCAA ACATGAGCAG CGATCAAGAC ACCGAGACTC GACACATTCT GGACTGTTTC 
AGAGACAGAC TCAAGCGGCT TATTCAGGTC GAGCCTCTGC TGGATCTGCT GGATTTCCTT 
GAACCGGACA AAAAAGAGCG AATAAAAGCC AAAGTGGCCT CGGAGGGGAA TATAAATGCC 
GTTTCTTTGC TTATCAATGA GATTATGCGC GCAGAGCTCC AGCAGGGGTG GTCGAGGACT 
CTGGTGACCG CGCTGGAGAC CGTCGGGTGC GGGCACGCCG CGCGGTATGT GCGCAACAGG 
CCGCCGGAGC CAGATGAAGA AGCCGAACAC GACAGCTGTG TGCGGCTTAT AGACCTGCTG 
CATCTCAGCC TGGTCAACAT GAAGACCCGG GACGTGTGTG TGCAGTGTGT GACTCTGGGG 
CTGCTAACGC AAGAGGACCA GGAGAATATT ATGACAGCCA CCGGGAACAA CGGAAATATA 
AATGGTGCTC GTCTGCTCCT CAAAAGGCTG GTGAAAAACG AAGCTGGCTG GTTTTCTAAA 
TTCCTTCAGG CTCTGGAGGA CACGGAGCAC CGTGACCTGA TGCGCGAGCT GCGAGGAGAG 
CCGTGCGAGG GGGACGAGGG GATGTCCGTG GACTCGTCGG ATGCTCAGGC TGAAGTGAAG 
GACACCGGTG CAGTCAGAAG AAACTCCATG TCTTCTCCTC CTCCGTCTTT CACCCCCAAC 
AGCTCTCTTC AGTCAGAGGA TCTGGACGAC AGTGTGGACA GCAGCGTTCT GGGTGTGGAG 
GCTGGAAATC GAGGGGTGGA GATGTATGAA GACGGTGAAG AAAAGGAGGA GAAAGATCTC 
AAAGAAGATG AGGACGATGA TTCATCAGCA AGTAAGAGGG AAATTAAACT GCGGGACTAT 
CAGATGGAGG TGGCCAGACC TGCTCTGGAG GAGAAGAACA TCATTGTCTG CCTGCCCACC 
GGATCCGGGA AGACCAGGGT CGCAGTGTTT ATCACCAAAG AGCATTTGGA GAGGGAGCAG 
CGGATGGGGC AGAAGGGGAA AGTGGTCGTC CTGGTCAACA AGGTCCCGCT GGTTGAGCAG 
CATTACAAGG CCGAGTTCGG GAGGTTTTTA AAGCACCAAT ACTCAGTGGA GCGGGTCAGC 
GGTGCCTCAC AGCTCAAAAT CTCCTTCCCA CAAATCATAG AGAAAAATGA CATCATCATC 
TGCACGGCGC AGATTCTGGA AAACTCTTTA GCCAAAGCCA AAAACGGCGA CGAGGACGGG 
ATCGAATTAT CACAGTTCAC CCTGATGGTT ATTGATGAGT GCCACCACAC GAAGAAGGGC 
GGTGTGTATA ACCACATCAT GATTCGCTAC CTGGAACAGA AGAATAGGAA CCAGCTGCTG 
AAGAAGCAGG ACAAAACTTT AGTTCCCATC CCTCAGATCC TGGGTCTGAC GGCCTCACCT 
GGTGTGGGAG GAGCGGTCAG CCAGCAGATG GCGGAGGAGC ATATTCTCCA GATCTGCGCA 
AACTTGGATG CCTTCACAAT CAAAACAAAG ACTTTCGAAG AAGAAGAGGC CAAAACACCA 
TTCAAGAGGA TTGCGAAAGC AGAAGAGAGG AAAGAGGACC CATTTGGAGA TGTGATCAAG 
AAGATCATGG ATGAAATCCA CACACATGCT GACCTGCAGC CCCTTTGTGA GCCCGGCACA 
CAGAACTATG AACAGTGGGT CGTGCAGAAA GGGCAGAACG CTGCTAAAGA GGAGAATCAG 
AATGTTCGCG TGTGTGCCGA ACACCTCCGC CAATACAATG AGGCTCTTCA TCAGAGCAAC 
ACCATTCGAA TGTCTGACGC TTTCCGGTTC CTGGACAAAT ATCACAATGA AGAGCTCAAG 
ACCAAATCTA GCCCTGACGA GGAAGGCAAC ATTACAATCA CGGACACAGA GAGATTCCTC 
TTCACTTTGT TCAAAGACAA AAAAGCGAAG CTGCAGGAGC TGATGGGAAA GCCGCAGTAT 
GAAAATAATA ATCTGGCCCA GCTGAAAACC ATCATCCTGA AGGAATTCTG CACCAGGGAG 
AAGGCGAGAG GCATCATATT CACCCAGACC CGCCTCAGCG CCATCGCTCT CTGCCAGTGG 
ATTGAAGAAA ACCCCAAGTT TGATGAAGTG GGAGTCCAAG CCAGTTATCT GATCGGCGGA 
GGAGACCAGA GCGTGGTGAA ACCCATGACC GCTGCGGAGC AGAAGGATGT GCTGAAAAGG 
TTTCGTACAG GCGAGATCAA TCTGCTAATA GCCACCACTG TTGCAGAAGA GGGTTTGGAC 
ATCGCTGAAT GTAATGTGGT CATTCGCTAT TGCCTGGTGA CCAACGAGGT CGCCATGATT 
CAGGCCCGCG GTCGAGGAAG AGCTGAGGAC AGTAGCTACA CGCTGGTGGC GGAGGCCGGG 
TCTGGAGTGG CGGAGAGAGA GAGTGTTAAC GAATACAGAG AGAAAATGAT GAGCAAAGCC 
ATCGCTAAAG TCTGCAAAAT GAACCGAGCT GACTACGAAA AGAAAATCAT GGAGTTTCAG 
ATCCAGGCCA TAATGGAGGA GAAAGTCAAG ACCAAAAAGA AACAGCAGAA GGGAATGATG 
AAGGAGGCGC CATCTAAAAT CCGCCTGAGC TGCAGGCAGT GCAGTGTGTT TGTGTGCTCT 
GGAGAAGACA TCGAGATCAT CGAGAAGATG CACCATGTCA ACGTTACCAA ACAGTTCAGA 
AAGCTGTTCA TAGTCCGAGA GAATGCGTCA CTACAGGAGC GACTCTTGGA CTACGAGACC 
AACGGAGTCA TTGCGTGCAA AAAATGTGGA CAGCAATGGG GTTCAATGAT GCTGTACAGA 
AGCACTGAAT GTCCCTGCCT TCATATCAAG AACTTTGTAG TCACATACGG CTCCAAGAAG 
AAGACGTTCA GCAAATGGAG AGAGCTGTCC ATAAGCTTCC CTGCATTTGA CTACACCCAG 
CACGCCGATC TCCTTGTTGA GGATTCAGAG GATGAAGATA TGGACACTAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RNF135 is a positive regulator of IFN expression and involved in RIG-I signaling pathway by targeting RIG-I.
Fish & shellfish immunology86474-479(2019 Mar)
Lai Y,Liang M,Hu,Zeng Z,Lin H,Yi G,Li M,Liu Z

Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome.
eLife7(2018 11)
Rajshekar S,Yao J,Arnold PK,Payne SG,Zhang Y,Bowman TV,Schmitz RJ,Edwards JR,Goll M

Diversification of the functions of proglucagon and glucagon receptor genes in fish.
General and comparative endocrinology261148-165(2018 05)
Irwin DM,Mojsov S

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia.
Scientific reports8(1)5165(2018 03)
Danilova N,Wilkes M,Bibikova E,Youn MY,Sakamoto KM,Lin S

Alternative Splicing Transcripts of Zebrafish LGP2 Gene Differentially Contribute to IFN Antiviral Response.
Journal of immunology (Baltimore, Md. : 1950)200(2)688-703(2018 01)
Zhang QM,Zhao X,Li Z,Wu M,Gui JF,Zhang YB

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ifih1 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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