Mfrp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mfrp
Entrez Gene ID	315597
Full Name	membrane frizzled-related protein
General protein information	Preferred Names membrane frizzled-related protein Names membrane frizzled-related protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q22

mRNA and Protein(s)

mRNA	Protein	Name
XM_006242933.3	XP_006242995.1	membrane frizzled-related protein isoform X1
NM_001108137.2	NP_001101607.1	membrane frizzled-related protein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	MFRP	XP_546484.2
Mus musculus (house mouse)	Mfrp	NP_667337.1
Gallus gallus (chicken)	MFRP	XP_003642649.2
Danio rerio (zebrafish)	LOC101885305	XP_005173402.1
Homo sapiens (human)	MFRP	NP_113621.1
Macaca mulatta (Rhesus monkey)	MFRP	XP_001104956.1
Pan troglodytes (chimpanzee)	MFRP	XP_003952099.1
Bos taurus (cattle)	MFRP	NP_001192829.1
Rattus norvegicus (Norway rat)	Mfrp	NP_001101607.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of MFRP Mutations in Chinese Families with High Hyperopia.
Xu Y, Guan L, Xiao X, Zhang J, Li S, Jiang H, Jia X, Yin Y, Guo X, Yang Z, Zhang Q
Optometry and vision science : official publication of the American Academy of Optometry93(1)19-26(2016 Jan)

Novel membrane frizzled-related protein gene mutation as cause of posterior microphthalmia resulting in high hyperopia with macular folds.
Wasmann RA, Wassink-Ruiter JS, Sundin OH, Morales E, Verheij JB, Pott JW
Acta ophthalmologica92(3)276-81(2014 May)

Gene therapy for retinitis pigmentosa caused by MFRP mutations: human phenotype and preliminary proof of concept.
Dinculescu A, Estreicher J, Zenteno JC, Aleman TS, Schwartz SB, Huang WC, Roman AJ, Sumaroka A, Li Q, Deng WT, Min SH, Chiodo VA, Neeley A, Liu X, Shu X, Matias-Florentino M, Buentello-Volante B, Boye SL, Cideciyan AV, Hauswirth WW, Jacobson SG
Human gene therapy23(4)367-76(2012 Apr)

Mutations in TULP1, NR2E3, and MFRP genes in Indian families with autosomal recessive retinitis pigmentosa.
Kannabiran C, Singh H, Sahini N, Jalali S, Mohan G
Molecular vision181165-74(2012)

Mouse model resources for vision research.
Won J, Shi LY, Hicks W, Wang J, Hurd R, Naggert JK, Chang B, Nishina PM
Journal of ophthalmology2011391384(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mfrp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mfrp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06728	NM_001108137.2 Latest version!	Rattus norvegicus membrane frizzled-related protein (Mfrp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa31080	XM_006242933.3 Latest version!	Rattus norvegicus membrane frizzled-related protein (Mfrp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mfrp ( NM_001108137.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101607.1 Rattus norvegicus membrane frizzled-related protein (Mfrp), mRNA.

Price & Availability↑

CloneID	ORa06728
Clone ID Related Accession (Same CDS sequence)	NM_001108137.2
Accession Version	NM_001108137.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1773bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Rattus norvegicus(Norway rat)
Product	membrane frizzled-related protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC112557.5. On Jun 23, 2009 this sequence version replaced NM_001108137.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGAAT ATGCCGATGT CACCCTCTGT CCAGAGGCAG CTGAGCTGAG CAAGACAGAG 
TTCTGCAATC CTGCTTTCGA CCTGGAAGCC GGGCCTTCTT GCCCTCCACC AGCATTACAG 
AAAAATGTCA GCAGCAGCCT CCAAGGTCCC TGGCATGTCC AGCGTCTCCG GGGGCTACAA 
CCAGACTGCC ACTTCTCCGG GCTCTGTATC CTGCTGCTCA GCGGCCTGCT GCTACTACTG 
CTGGGGCTGC TGGTGGCTGT CATCCTGGCT CAGTTGCAGG CTACATCTCT CCCCAGGACT 
ACCAAGAACC CACTGCCCAC CCGAGGAGGC CTCACCCCCA CGGGTGTCAT TCCCAGCACC 
ACCCCTAACA CCACCACCAC CACCACCACC ACCCCAGCAA TCACAGGGCG GCAAGAGGCA 
GCCATGAGCC CTACACACCA AACCACCTGT GGAGGCCTCC TTCCTGGTCC CAGTGGTTTC 
TTCAGCAGTC CCAACTACCC AGACCTTTAC CCACCCCACA GCCACTGCGT CTGGCATATC 
CAGGTAGCCA CAGGCCAGAC AATACAGCTC AAGATTCAAG TGCTCAGCAC AGAAAGCATG 
CTCGCCTGTC TTTTTGATCG CTTGGAAATT AGCCCAGCGC CTACAGGCCC TCTGCTCAGA 
ATGTGTGGTA AAACACCTCC TGCCACAGTT AACACCAACA CCAGTCACCT CCGTGTGTCC 
TTCGTCTCTG ATAACGATGT AGAAGGGTCT GGTTTCCAGG CCTGGTACCA AGCAGTGGCC 
CCTGGACATT GGAGCTGTAC CCACTACGAG TTCCACTGTG ACCTGCTCCT CTGCCTGAAG 
CAAGACTCTG TGTGTGACGG CATTAAGGAC TGCATCGATG GCAGTGATGA GGCCAACTGC 
AGTGCCAAGA CGTTGGGGTG TGGAGGGAAC CTGACTGAGC TCTCTGGGGT GTTCTCTACC 
CCAAACTACC CACAGCACTA CCCTCACCAA CAGCTTTGTA CCTGGTATAT CAAAGTGCCC 
GTGGGATACA GGATAAGACT AGAGTTCCAC AACTTCAGCC TGGAAGAACA AACTGAATGC 
AAGTTTGACT ACGTGGAGGT GTATGAGGCC AGCAACTCAG GAACATTCAG CTCCCTGGGC 
AGGTTCTGTG GAGCAGAGCC ACCATCCCAC CTCGTCTCCT CGCAGCACCA GCTGACTGTA 
ATCTTCAAGA CTGATCTTGG TATCAGCAGT GGGGGCTTTT TAGCAACCTA CCAGGCCATC 
AATACGACAG AGAGTGGGTG CCCCTGGGCA GACCTTTGTG GACCCAGAGA GTTCTGCCAG 
AGCAGAGTAC GTAGAGAACT GCAACGGATT TGTGACTTAT GGAAAGACTG TGCAAATGAC 
AGCAATGACA ACTGCAACAG CCACTTGTCC CCACAACTGG ACCTGACCTG TGAACCTGTC 
CAGGTGGAGA TGTGCCTTGG ACTAAGCTAC AATACCACAG CCTTCCCTAA CATCTGGGTG 
GGCCTGGCCA CACAGATGGA GGTGACAGAT ATCCTCAGAG GCTACAAGAG CCTGACAAGT 
CTACCCTGCT ACCAGACTTT CCGGAGGTTC CTCTGTGGGC TGCTTGAACC TCGATGCACC 
TCACTGGGCA CTATCCTACC CCCTTGTCGT TCTGTCTGCC AGGAGGCAGA ACAACAGTGC 
CAGTCTAGCC TGGCATTACT GGGCATCCCC TGGCCTTTCA ACTGCAACAG GCTGCCTGTG 
CCGGCTAGCC TGGAAGCTTG CTCCCAGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101607.1
CDS	151..1923
Translation	MKEYADVTLCPEAAELSKTEFCNPAFDLEAGPSCPPPALQKNVSSSLQGPWHVQRLRGLQPDCHFSGLCILLLSGLLLLLLGLLVAVILAQLQATSLPRTTKNPLPTRGGLTPTGVIPSTTPNTTTTTTTTPAITGRQEAAMSPTHQTTCGGLLPGPSGFFSSPNYPDLYPPHSHCVWHIQVATGQTIQLKIQVLSTESMLACLFDRLEISPAPTGPLLRMCGKTPPATVNTNTSHLRVSFVSDNDVEGSGFQAWYQAVAPGHWSCTHYEFHCDLLLCLKQDSVCDGIKDCIDGSDEANCSAKTLGCGGNLTELSGVFSTPNYPQHYPHQQLCTWYIKVPVGYRIRLEFHNFSLEEQTECKFDYVEVYEASNSGTFSSLGRFCGAEPPSHLVSSQHQLTVIFKTDLGISSGGFLATYQAINTTESGCPWADLCGPREFCQSRVRRELQRICDLWKDCANDSNDNCNSHLSPQLDLTCEPVQVEMCLGLSYNTTAFPNIWVGLATQMEVTDILRGYKSLTSLPCYQTFRRFLCGLLEPRCTSLGTILPPCRSVCQEAEQQCQSSLALLGIPWPFNCNRLPVPASLEACSQP

Target ORF information:

RefSeq Version	NM_001108137.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus membrane frizzled-related protein (Mfrp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108137.2

ORF Insert Sequence:

ATGAAGGAAT ATGCCGATGT CACCCTCTGT CCAGAGGCAG CTGAGCTGAG CAAGACAGAG 
TTCTGCAATC CTGCTTTCGA CCTGGAAGCC GGGCCTTCTT GCCCTCCACC AGCATTACAG 
AAAAATGTCA GCAGCAGCCT CCAAGGTCCC TGGCATGTCC AGCGTCTCCG GGGGCTACAA 
CCAGACTGCC ACTTCTCCGG GCTCTGTATC CTGCTGCTCA GCGGCCTGCT GCTACTACTG 
CTGGGGCTGC TGGTGGCTGT CATCCTGGCT CAGTTGCAGG CTACATCTCT CCCCAGGACT 
ACCAAGAACC CACTGCCCAC CCGAGGAGGC CTCACCCCCA CGGGTGTCAT TCCCAGCACC 
ACCCCTAACA CCACCACCAC CACCACCACC ACCCCAGCAA TCACAGGGCG GCAAGAGGCA 
GCCATGAGCC CTACACACCA AACCACCTGT GGAGGCCTCC TTCCTGGTCC CAGTGGTTTC 
TTCAGCAGTC CCAACTACCC AGACCTTTAC CCACCCCACA GCCACTGCGT CTGGCATATC 
CAGGTAGCCA CAGGCCAGAC AATACAGCTC AAGATTCAAG TGCTCAGCAC AGAAAGCATG 
CTCGCCTGTC TTTTTGATCG CTTGGAAATT AGCCCAGCGC CTACAGGCCC TCTGCTCAGA 
ATGTGTGGTA AAACACCTCC TGCCACAGTT AACACCAACA CCAGTCACCT CCGTGTGTCC 
TTCGTCTCTG ATAACGATGT AGAAGGGTCT GGTTTCCAGG CCTGGTACCA AGCAGTGGCC 
CCTGGACATT GGAGCTGTAC CCACTACGAG TTCCACTGTG ACCTGCTCCT CTGCCTGAAG 
CAAGACTCTG TGTGTGACGG CATTAAGGAC TGCATCGATG GCAGTGATGA GGCCAACTGC 
AGTGCCAAGA CGTTGGGGTG TGGAGGGAAC CTGACTGAGC TCTCTGGGGT GTTCTCTACC 
CCAAACTACC CACAGCACTA CCCTCACCAA CAGCTTTGTA CCTGGTATAT CAAAGTGCCC 
GTGGGATACA GGATAAGACT AGAGTTCCAC AACTTCAGCC TGGAAGAACA AACTGAATGC 
AAGTTTGACT ACGTGGAGGT GTATGAGGCC AGCAACTCAG GAACATTCAG CTCCCTGGGC 
AGGTTCTGTG GAGCAGAGCC ACCATCCCAC CTCGTCTCCT CGCAGCACCA GCTGACTGTA 
ATCTTCAAGA CTGATCTTGG TATCAGCAGT GGGGGCTTTT TAGCAACCTA CCAGGCCATC 
AATACGACAG AGAGTGGGTG CCCCTGGGCA GACCTTTGTG GACCCAGAGA GTTCTGCCAG 
AGCAGAGTAC GTAGAGAACT GCAACGGATT TGTGACTTAT GGAAAGACTG TGCAAATGAC 
AGCAATGACA ACTGCAACAG CCACTTGTCC CCACAACTGG ACCTGACCTG TGAACCTGTC 
CAGGTGGAGA TGTGCCTTGG ACTAAGCTAC AATACCACAG CCTTCCCTAA CATCTGGGTG 
GGCCTGGCCA CACAGATGGA GGTGACAGAT ATCCTCAGAG GCTACAAGAG CCTGACAAGT 
CTACCCTGCT ACCAGACTTT CCGGAGGTTC CTCTGTGGGC TGCTTGAACC TCGATGCACC 
TCACTGGGCA CTATCCTACC CCCTTGTCGT TCTGTCTGCC AGGAGGCAGA ACAACAGTGC 
CAGTCTAGCC TGGCATTACT GGGCATCCCC TGGCCTTTCA ACTGCAACAG GCTGCCTGTG 
CCGGCTAGCC TGGAAGCTTG CTCCCAGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mfrp ( XM_006242933.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242995.1 Rattus norvegicus membrane frizzled-related protein (Mfrp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa31080
Clone ID Related Accession (Same CDS sequence)	XM_006242933.3
Accession Version	XM_006242933.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	membrane frizzled-related protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242933.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGAAT ATGCCGATGT CACCCTCTGT CCAGAGGCAG CTGAGCTGAG CAAGACAGAG 
TTCTGCAATC CTGCTTTCGA CCTGGAAGCC GGGCCTTCTT GCCCTCCACC AGCATTACAG 
AAAAATGTCA GCAGCAGCCT CCAAGGTCCC TGGCATGTCC AGCGTCTCCG GGGGCTACAA 
CCAGACTGCC ACTTCTCCGG GCTCTGTATC CTGCTGCTCA GCGGCCTGCT GCTACTACTG 
CTGGGGCTGC TGGTGGCTGT CATCCTGGCT CAGTTGCAGG CTACATCTCT CCCCAGGACT 
ACCAAGAACC CACTGCCCAC CCGAGGAGGC CTCACCCCCA CGGGTGTCAT TCCCAGCACC 
ACCCCTAACA CCACCACCAC CACCACCACC ACCCCAGCAA TCACAGGGCG GCAAGAGGCA 
GCCATGAGCC CTACACACCA AACCACCTGT GGAGGCCTCC TTCCTGGTCC CAGTGGTTTC 
TTCAGCAGTC CCAACTACCC AGACCTTTAC CCACCCCACA GCCACTGCGT CTGGCATATC 
CAGGTAGCCA CAGGCCAGAC AATACAGCTC AAGATTCAAG TGCTCAGCAC AGAAAGCATG 
CTCGCCTGTC TTTTTGATCG CTTGGAAATT AGCCCAGCGC CTACAGGCCC TCTGCTCAGA 
ATGTGTGGTA AAACACCTCC TGCCACAGTT AACACCAACA CCAGTCACCT CCGTGTGTCC 
TTCGTCTCTG ATAACGATGT AGAAGGGTCT GGTTTCCAGG CCTGGTACCA AGCAGTGGCC 
CCTGGACATT GGAGCTGTAC CCACTACGAG TTCCACTGTG ACCTGCTCCT CTGCCTGAAG 
CAAGACTCTG TGTGTGACGG CATTAAGGAC TGCATCGATG GCAGTGATGA GGCCAACTGC 
AGTGCCAAGA CGTTGGGGTG TGGAGGGAAC CTGACTGAGC TCTCTGGGGT GTTCTCTACC 
CCAAACTACC CACAGCACTA CCCTCACCAA CAGCTTTGTA CCTGGTATAT CAAAGTGCCC 
GTGGGATACA GGATAAGACT AGAGTTCCAC AACTTCAGCC TGGAAGAACA AACTGAATGC 
AAGTTTGACT ACGTGGAGGT GTATGAGGCC AGCAACTCAG GAACATTCAG CTCCCTGGGC 
AGGTTCTGTG GAGCAGAGCC ACCATCCCAC CTCGTCTCCT CGCAGCACCA GCTGACTGTA 
ATCTTCAAGA CTGATCTTGG TATCAGCAGT GGGGGCTTTT TAGCAACCTA CCAGGCCATC 
AATACGACAG AGAACCTTTG TGGACCCAGA GAGTTCTGCC AGAGCAGAGT ACGTAGAGAA 
CTGCAACGGA TTTGTGACTT ATGGAAAGAC TGTGCAAATG ACAGCAATGA CAACTGCAAC 
AGCCACTTGT CCCCACAACT GGACCTGACC TGTGAACCTG TCCAGGTGGA GATGTGCCTT 
GGACTAAGCT ACAATACCAC AGCCTTCCCT AACATCTGGG TGGGCCTGGC CACACAGATG 
GAGGTGACAG ATATCCTCAG AGGCTACAAG AGCCTGACAA GTCTACCCTG CTACCAGACT 
TTCCGGAGGT TCCTCTGTGG GCTGCTTGAA CCTCGATGCA CCTCACTGGG CACTATCCTA 
CCCCCTTGTC GTTCTGTCTG CCAGGAGGCA GAACAACAGT GCCAGTCTAG CCTGGCATTA 
CTGGGCATCC CCTGGCCTTT CAACTGCAAC AGGCTGCCTG TGCCGGCTAG CCTGGAAGCT 
TGCTCCCAGC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242995.1
CDS	690..2444
Translation	MKEYADVTLCPEAAELSKTEFCNPAFDLEAGPSCPPPALQKNVSSSLQGPWHVQRLRGLQPDCHFSGLCILLLSGLLLLLLGLLVAVILAQLQATSLPRTTKNPLPTRGGLTPTGVIPSTTPNTTTTTTTTPAITGRQEAAMSPTHQTTCGGLLPGPSGFFSSPNYPDLYPPHSHCVWHIQVATGQTIQLKIQVLSTESMLACLFDRLEISPAPTGPLLRMCGKTPPATVNTNTSHLRVSFVSDNDVEGSGFQAWYQAVAPGHWSCTHYEFHCDLLLCLKQDSVCDGIKDCIDGSDEANCSAKTLGCGGNLTELSGVFSTPNYPQHYPHQQLCTWYIKVPVGYRIRLEFHNFSLEEQTECKFDYVEVYEASNSGTFSSLGRFCGAEPPSHLVSSQHQLTVIFKTDLGISSGGFLATYQAINTTENLCGPREFCQSRVRRELQRICDLWKDCANDSNDNCNSHLSPQLDLTCEPVQVEMCLGLSYNTTAFPNIWVGLATQMEVTDILRGYKSLTSLPCYQTFRRFLCGLLEPRCTSLGTILPPCRSVCQEAEQQCQSSLALLGIPWPFNCNRLPVPASLEACSQP

Target ORF information:

RefSeq Version	XM_006242933.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus membrane frizzled-related protein (Mfrp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242933.3

ORF Insert Sequence:

ATGAAGGAAT ATGCCGATGT CACCCTCTGT CCAGAGGCAG CTGAGCTGAG CAAGACAGAG 
TTCTGCAATC CTGCTTTCGA CCTGGAAGCC GGGCCTTCTT GCCCTCCACC AGCATTACAG 
AAAAATGTCA GCAGCAGCCT CCAAGGTCCC TGGCATGTCC AGCGTCTCCG GGGGCTACAA 
CCAGACTGCC ACTTCTCCGG GCTCTGTATC CTGCTGCTCA GCGGCCTGCT GCTACTACTG 
CTGGGGCTGC TGGTGGCTGT CATCCTGGCT CAGTTGCAGG CTACATCTCT CCCCAGGACT 
ACCAAGAACC CACTGCCCAC CCGAGGAGGC CTCACCCCCA CGGGTGTCAT TCCCAGCACC 
ACCCCTAACA CCACCACCAC CACCACCACC ACCCCAGCAA TCACAGGGCG GCAAGAGGCA 
GCCATGAGCC CTACACACCA AACCACCTGT GGAGGCCTCC TTCCTGGTCC CAGTGGTTTC 
TTCAGCAGTC CCAACTACCC AGACCTTTAC CCACCCCACA GCCACTGCGT CTGGCATATC 
CAGGTAGCCA CAGGCCAGAC AATACAGCTC AAGATTCAAG TGCTCAGCAC AGAAAGCATG 
CTCGCCTGTC TTTTTGATCG CTTGGAAATT AGCCCAGCGC CTACAGGCCC TCTGCTCAGA 
ATGTGTGGTA AAACACCTCC TGCCACAGTT AACACCAACA CCAGTCACCT CCGTGTGTCC 
TTCGTCTCTG ATAACGATGT AGAAGGGTCT GGTTTCCAGG CCTGGTACCA AGCAGTGGCC 
CCTGGACATT GGAGCTGTAC CCACTACGAG TTCCACTGTG ACCTGCTCCT CTGCCTGAAG 
CAAGACTCTG TGTGTGACGG CATTAAGGAC TGCATCGATG GCAGTGATGA GGCCAACTGC 
AGTGCCAAGA CGTTGGGGTG TGGAGGGAAC CTGACTGAGC TCTCTGGGGT GTTCTCTACC 
CCAAACTACC CACAGCACTA CCCTCACCAA CAGCTTTGTA CCTGGTATAT CAAAGTGCCC 
GTGGGATACA GGATAAGACT AGAGTTCCAC AACTTCAGCC TGGAAGAACA AACTGAATGC 
AAGTTTGACT ACGTGGAGGT GTATGAGGCC AGCAACTCAG GAACATTCAG CTCCCTGGGC 
AGGTTCTGTG GAGCAGAGCC ACCATCCCAC CTCGTCTCCT CGCAGCACCA GCTGACTGTA 
ATCTTCAAGA CTGATCTTGG TATCAGCAGT GGGGGCTTTT TAGCAACCTA CCAGGCCATC 
AATACGACAG AGAACCTTTG TGGACCCAGA GAGTTCTGCC AGAGCAGAGT ACGTAGAGAA 
CTGCAACGGA TTTGTGACTT ATGGAAAGAC TGTGCAAATG ACAGCAATGA CAACTGCAAC 
AGCCACTTGT CCCCACAACT GGACCTGACC TGTGAACCTG TCCAGGTGGA GATGTGCCTT 
GGACTAAGCT ACAATACCAC AGCCTTCCCT AACATCTGGG TGGGCCTGGC CACACAGATG 
GAGGTGACAG ATATCCTCAG AGGCTACAAG AGCCTGACAA GTCTACCCTG CTACCAGACT 
TTCCGGAGGT TCCTCTGTGG GCTGCTTGAA CCTCGATGCA CCTCACTGGG CACTATCCTA 
CCCCCTTGTC GTTCTGTCTG CCAGGAGGCA GAACAACAGT GCCAGTCTAG CCTGGCATTA 
CTGGGCATCC CCTGGCCTTT CAACTGCAAC AGGCTGCCTG TGCCGGCTAG CCTGGAAGCT 
TGCTCCCAGC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of MFRP Mutations in Chinese Families with High Hyperopia.
Optometry and vision science : official publication of the American Academy of Optometry93(1)19-26(2016 Jan)
Xu Y,Guan L,Xiao X,Zhang J,Li S,Jiang H,Jia X,Yin Y,Guo X,Yang Z,Zhang Q

Novel membrane frizzled-related protein gene mutation as cause of posterior microphthalmia resulting in high hyperopia with macular folds.
Acta ophthalmologica92(3)276-81(2014 May)
Wasmann RA,Wassink-Ruiter JS,Sundin OH,Morales E,Verheij JB,Pott JW

Gene therapy for retinitis pigmentosa caused by MFRP mutations: human phenotype and preliminary proof of concept.
Human gene therapy23(4)367-76(2012 Apr)
Dinculescu A,Estreicher J,Zenteno JC,Aleman TS,Schwartz SB,Huang WC,Roman AJ,Sumaroka A,Li Q,Deng WT,Min SH,Chiodo VA,Neeley A,Liu X,Shu X,Matias-Florentino M,Buentello-Volante B,Boye SL,Cideciyan AV,Hauswirth WW,Jacobson SG

Mutations in TULP1, NR2E3, and MFRP genes in Indian families with autosomal recessive retinitis pigmentosa.
Molecular vision181165-74(2012)
Kannabiran C,Singh H,Sahini N,Jalali S,Mohan G

Mouse model resources for vision research.
Journal of ophthalmology2011391384(2011)
Won J,Shi LY,Hicks W,Wang J,Hurd R,Naggert JK,Chang B,Nishina PM

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Mfrp cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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