Fadd cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fadd
Entrez Gene ID	266610
Full Name	Fas associated via death domain
Synonyms	Mort1
General protein information	Preferred Names Fas associated via death domain Names FAS-associated death domain protein Fas (TNFRSF6)-associated via death domain protein FADD
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q42
Summary	an important adaptor molecule in apoptosis signaling; may mediate hepatocyte death [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_152937.2	NP_690920.1	FAS-associated death domain protein

Pathways from BioSystems

Homologies

Bos taurus (cattle)	FADD	NP_001007817.1
Xenopus tropicalis (tropical clawed frog)	fadd	XP_002934114.1
Mus musculus (house mouse)	Fadd	NP_034305.1
Macaca mulatta (Rhesus monkey)	LOC708606	XP_001100468.1
Rattus norvegicus (Norway rat)	Fadd	NP_690920.1
Gallus gallus (chicken)	FADD	XP_421073.2
Homo sapiens (human)	FADD	NP_003815.1
Pan troglodytes (chimpanzee)	FADD	XP_508611.2
Danio rerio (zebrafish)	fadd	XP_001923893.1

Gene Ontology
Bibliography

Related articles in PubMed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.
Van Quickelberghe E, De Sutter D, van Loo G, Eyckerman S, Gevaert K
Scientific data5180289(2018 12)

Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal FADD.
Hernández-Hernández E, Miralles A, Esteban S, García-Fuster MJ
Neurobiology of aging71115-126(2018 11)

Edaravone attenuates neuronal apoptosis in hypoxic-ischemic brain damage rat model via suppression of TRAIL signaling pathway.
Li C, Mo Z, Lei J, Li H, Fu R, Huang Y, Luo S, Zhang L
The international journal of biochemistry & cell biology99169-177(2018 06)

Differential activation of CD95-mediated apoptosis related proteins in proximal and distal tubules during rat renal development.
Song XF, Tian H, Zhang ZX
Tissue & cell48(5)417-24(2016 Oct)

Rice Hull Extract Suppresses Benign Prostate Hyperplasia by Decreasing Inflammation and Regulating Cell Proliferation in Rats.
Kim CY, Chung KS, Cheon SY, Lee JH, Park YB, An HJ
Journal of medicinal food19(8)746-54(2016 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fadd gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fadd cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02986	NM_152937.2 Latest version!	Rattus norvegicus Fas associated via death domain (Fadd), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fadd ( NM_152937.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_690920.1 Rattus norvegicus Fas associated via death domain (Fadd), mRNA.

Price & Availability↑

CloneID	ORa02986
Clone ID Related Accession (Same CDS sequence)	NM_152937.2
Accession Version	NM_152937.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570550400000
Organism	Rattus norvegicus(Norway rat)
Product	FAS-associated death domain protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF406779.1. On Jun 10, 2007 this sequence version replaced NM_152937.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF406779.1, AJ441127.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906351, SAMN01906357 [ECO:0000348] ##Evidence-Data-END##

ATGGACCCAT TCCTGGTGCT GCTGCACTCG CTGTCCAGCA GCCTGTCGGG CAACGATCTG 
ACGGATCTCA AGTTCCTGTG CCGCGAGCGC GTGAGTAAAC GAAAGCTGGA GCGCGTGCAG 
AGTGGCCTGG ACCTGTTCTC GGTGCTGCTG GAGCAGAACG ATCTGGAGCG CGGGCACACC 
GGGCTGCTGC GCGAGTTGCT GGCCTCGCTG GGCAGACACG ACCTACTGCA GCGCCTGGAC 
GACTTCGAGG CGGGGGCGAC GACTGCTGCA ACCCCGGGGG AGGCAGATCT GCGGGTGGCA 
TTTGACATTG TGTGTGACAA TGTGGGGAGA GACTGGAAAA GACTGGCCCG TGAGCTGAAG 
GTGTCTGAGG CCAAGATTGA TGGCATTGAG GAGAGGTACC CCCGAAGCCT GAGTGATCGG 
GTAAGGGAGA CTCTGCGAGT CTGGAAGAAT GTCGAGAAGG AGAACGCCTC GGTGGCTGGA 
CTGGTCAAGG CACTGCGGGC CTGCCGGCTG AACCTGGTGG CTGACCTGGT GGAAGAAGCA 
TTGATGGCCC AGGGATCTGT GAGCAAGAGT GATGATACAT CCTCAGCGCT GAGGGATTCA 
ACTGTGTCTT TCTCAGAAAC ACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690920.1
CDS	39..665
Translation	MDPFLVLLHSLSSSLSGNDLTDLKFLCRERVSKRKLERVQSGLDLFSVLLEQNDLERGHTGLLRELLASLGRHDLLQRLDDFEAGATTAATPGEADLRVAFDIVCDNVGRDWKRLARELKVSEAKIDGIEERYPRSLSDRVRETLRVWKNVEKENASVAGLVKALRACRLNLVADLVEEALMAQGSVSKSDDTSSALRDSTVSFSETP

Target ORF information:

RefSeq Version	NM_152937.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Fas associated via death domain (Fadd), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152937.2

ORF Insert Sequence:

ATGGACCCAT TCCTGGTGCT GCTGCACTCG CTGTCCAGCA GCCTGTCGGG CAACGATCTG 
ACGGATCTCA AGTTCCTGTG CCGCGAGCGC GTGAGTAAAC GAAAGCTGGA GCGCGTGCAG 
AGTGGCCTGG ACCTGTTCTC GGTGCTGCTG GAGCAGAACG ATCTGGAGCG CGGGCACACC 
GGGCTGCTGC GCGAGTTGCT GGCCTCGCTG GGCAGACACG ACCTACTGCA GCGCCTGGAC 
GACTTCGAGG CGGGGGCGAC GACTGCTGCA ACCCCGGGGG AGGCAGATCT GCGGGTGGCA 
TTTGACATTG TGTGTGACAA TGTGGGGAGA GACTGGAAAA GACTGGCCCG TGAGCTGAAG 
GTGTCTGAGG CCAAGATTGA TGGCATTGAG GAGAGGTACC CCCGAAGCCT GAGTGATCGG 
GTAAGGGAGA CTCTGCGAGT CTGGAAGAAT GTCGAGAAGG AGAACGCCTC GGTGGCTGGA 
CTGGTCAAGG CACTGCGGGC CTGCCGGCTG AACCTGGTGG CTGACCTGGT GGAAGAAGCA 
TTGATGGCCC AGGGATCTGT GAGCAAGAGT GATGATACAT CCTCAGCGCT GAGGGATTCA 
ACTGTGTCTT TCTCAGAAAC ACCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.
Scientific data5180289(2018 12)
Van Quickelberghe E,De Sutter D,van Loo G,Eyckerman S,Gevaert K

Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal FADD.
Neurobiology of aging71115-126(2018 11)
Hernández-Hernández E,Miralles A,Esteban S,García-Fuster MJ

Edaravone attenuates neuronal apoptosis in hypoxic-ischemic brain damage rat model via suppression of TRAIL signaling pathway.
The international journal of biochemistry & cell biology99169-177(2018 06)
Li C,Mo Z,Lei J,Li H,Fu R,Huang Y,Luo S,Zhang L

Differential activation of CD95-mediated apoptosis related proteins in proximal and distal tubules during rat renal development.
Tissue & cell48(5)417-24(2016 Oct)
Song XF,Tian H,Zhang ZX

Rice Hull Extract Suppresses Benign Prostate Hyperplasia by Decreasing Inflammation and Regulating Cell Proliferation in Rats.
Journal of medicinal food19(8)746-54(2016 Aug)
Kim CY,Chung KS,Cheon SY,Lee JH,Park YB,An HJ