| Gene Symbol | Il1b |
| Entrez Gene ID | 24494 |
| Full Name | interleukin 1 beta |
| Synonyms | IL-1F2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | an inflammatory cytokine [RGD, Feb 2006]. |
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Il1b cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Il1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa13121 Clone ID Related Accession (Same CDS sequence) NM_031512.2 Accession Version NM_031512.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 807bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1577289600000 Organism Rattus norvegicus(Norway rat) Product interleukin-1 beta Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC091141.1. On Oct 12, 2007 this sequence version replaced NM_031512.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC091141.1, M98820.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781ATGGCAACTG TCCCTGAACT CAACTGTGAA ATAGCAGCTT TCGACAGTGA GGAGAATGAC
CTGTTCTTTG AGGCTGACAG ACCCCAAAAG ATTAAGGATT GCTTCCAAGC CCTTGACTTG
GGCTGTCCAG ATGAGAGCAT CCAGCTTCAA ATCTCACAGC AGCATCTCGA CAAGAGCTTC
AGGAAGGCAG TGTCACTCAT TGTGGCTGTG GAGAAGCTGT GGCAGCTACC TATGTCTTGC
CCGTGGAGCT TCCAGGATGA GGACCCAAGC ACCTTCTTTT CCTTCATCTT TGAAGAAGAG
CCCGTCCTCT GTGACTCGTG GGATGATGAC GACCTGCTAG TGTGTGATGT TCCCATTAGA
CAGCTGCACT GCAGGCTTCG AGATGAACAA CAAAAATGCC TCGTGCTGTC TGACCCATGT
GAGCTGAAAG CTCTCCACCT CAATGGACAG AACATAAGCC AACAAGTGGT ATTCTCCATG
AGCTTTGTAC AAGGAGAGAC AAGCAACGAC AAAATCCCTG TGGCCTTGGG CCTCAAGGGG
AAGAATCTAT ACCTGTCCTG TGTGATGAAA GACGGCACAC CCACCCTGCA GCTGGAGAGT
GTGGATCCCA AACAATACCC AAAGAAGAAG ATGGAAAAGC GGTTTGTCTT CAACAAGATA
GAAGTCAAGA CCAAAGTGGA GTTTGAGTCT GCACAGTTCC CCAACTGGTA CATCAGCACC
TCTCAAGCAG AGCACAGACC TGTCTTCCTA GGAAACAGCA ATGGTCGGGA CATAGTTGAC
TTCACCATGG AACCCGTGTC TTCCTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_113700.2 CDS 57..863 Translation 
Target ORF information:
RefSeq Version NM_031512.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus interleukin 1 beta (Il1b), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_031512.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781ATGGCAACTG TCCCTGAACT CAACTGTGAA ATAGCAGCTT TCGACAGTGA GGAGAATGAC
CTGTTCTTTG AGGCTGACAG ACCCCAAAAG ATTAAGGATT GCTTCCAAGC CCTTGACTTG
GGCTGTCCAG ATGAGAGCAT CCAGCTTCAA ATCTCACAGC AGCATCTCGA CAAGAGCTTC
AGGAAGGCAG TGTCACTCAT TGTGGCTGTG GAGAAGCTGT GGCAGCTACC TATGTCTTGC
CCGTGGAGCT TCCAGGATGA GGACCCAAGC ACCTTCTTTT CCTTCATCTT TGAAGAAGAG
CCCGTCCTCT GTGACTCGTG GGATGATGAC GACCTGCTAG TGTGTGATGT TCCCATTAGA
CAGCTGCACT GCAGGCTTCG AGATGAACAA CAAAAATGCC TCGTGCTGTC TGACCCATGT
GAGCTGAAAG CTCTCCACCT CAATGGACAG AACATAAGCC AACAAGTGGT ATTCTCCATG
AGCTTTGTAC AAGGAGAGAC AAGCAACGAC AAAATCCCTG TGGCCTTGGG CCTCAAGGGG
AAGAATCTAT ACCTGTCCTG TGTGATGAAA GACGGCACAC CCACCCTGCA GCTGGAGAGT
GTGGATCCCA AACAATACCC AAAGAAGAAG ATGGAAAAGC GGTTTGTCTT CAACAAGATA
GAAGTCAAGA CCAAAGTGGA GTTTGAGTCT GCACAGTTCC CCAACTGGTA CATCAGCACC
TCTCAAGCAG AGCACAGACC TGTCTTCCTA GGAAACAGCA ATGGTCGGGA CATAGTTGAC
TTCACCATGG AACCCGTGTC TTCCTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Proteins from Plumeria pudica latex exhibit protective effect in acetic acid induced colitis in mice by inhibition of pro-inflammatory mechanisms and oxidative stress.
Life sciences231116535(2019 Aug)
Oliveira NVM,Souza BDS,Moita LA,Oliveira LES,Brito FC,Magalhães DA,Batista JA,Sousa SG,Brito TV,Sousa FBM,Alves EHP,Vasconcelos DFP,Freitas CDT,Ramos MV,Barbosa ALDR,Oliveira JS
Ellagic Acid Prevents Oxidative Stress, Inflammation, and Histopathological Alterations in Acrylamide-Induced Hepatotoxicity in Wistar Rats.
Journal of dietary supplements1-12(2019 Jul)
Karimi MY,Fatemi I,Kalantari H,Mombeini MA,Mehrzadi S,Goudarzi M
Sitagliptin ameliorates thioacetamide-induced acute liver injury via modulating TLR4/NF-KB signaling pathway in mice.
Life sciences228266-273(2019 Jul)
El-Kashef DH,Serrya MS
Protective Effect of Cashew Gum (Anacardium occidentale L.) on 5-Fluorouracil-Induced Intestinal Mucositis.
Pharmaceuticals (Basel, Switzerland)12(2)(2019 Apr)
de Miranda JAL,Barreto JEF,Martins DS,de Souza Pimentel PV,da Silva Costa DV,E Silva RR,de Souza LKM,de Lima CNC,Rocha JA,de Freitas APF,da Silva DA,Scafuri AG,de Leitão RFC,de Castro Brito GA,Medeiros JVR,Cerqueira GS
Association of ENAM, TUFT1, MMP13, IL1B, IL10 and IL1RN gene polymorphism and dental caries susceptibility in Chinese children.
The Journal of international medical research47(4)1696-1704(2019 Apr)
Hu XP,Song TZ,Zhu YY,Wu LL,Zhang X,Zhou JY,Li ZQ
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