| Gene Symbol | Mllt3 |
| Entrez Gene ID | 114510 |
| Full Name | MLLT3, super elongation complex subunit |
| Synonyms | Af-9,Af9 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | mouse homolog regulates pattern formation during embryogenesis [RGD, Feb 2006]. |
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Mllt3 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Mllt3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mllt3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa10404 Clone ID Related Accession (Same CDS sequence) NM_053718.2 Accession Version NM_053718.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1113bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1506700800000 Organism Rattus norvegicus(Norway rat) Product protein AF-9 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ006295.1. On Jun 24, 2008 this sequence version replaced NM_053718.1. ##Evidence-Data-START## CDS exon combination :: AJ006295.1, BC129089.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGAAGGAGC ACAAGGAAAA ACCTTCTAAG GACTCCAGAG AACATAAAAG TGCCTTCAAA
GAACCTTCCA GGGATCACAA CAAATCTTCC AAAGACTCCT CCAAGAAACC CAAAGAAAAC
AAACCACTGA AAGAAGAAAA AATCGTTCCT AAGATGGCCT TCAAGGAGCC TAAACCCATG
TCAAAAGAGC CAAAAGCAGA CAGTAACTTA CTCACCGTCA CCAGTGCACA GCAGGACAAG
AAGGCGCCTA GTAAAAGGCC CCCTGTTTCA GATTCTGAAG AACTCTCAGC CAAAAAAAGG
AAAAAGAGTA GCTCCGAGGC TTTATTTAAA AGTTTTTCTA GCGCGCCCCC ACTGATACTC
ACTTGTTCTG CTGACAAAAA ACAGATAAAA GATAAATCTC ATGTCAAGAT GGGAAAGGTC
AAAATCGAGA GCGAGACTTC AGAGAAGAAG AAGTCGACAC TGCCACCATT TGATGATATC
GTGGATCCCA ACGACTCAGA CGTGGAGGAG AACATGTCCT CAAAATCTGA CTCAGAGCAA
CCCAGTCCTG CCAGTTCCAG TTCCAGTTCC AGCTCCAGCT TCACGCCGTC TCAGACCAGG
CAGCAAGGTC CTTTAAGGTC GATCATGAAA GATCTGCATT CCGATGACAA CGAGGAGGAG
TCTGATGAGG CCGAGGACAA TGACAATGAC TCTGAGATGG AAAGGCCTGT AAACAGAGGG
GGAAGCCGAA GTCGCAGGGT CAGCTTGAGT GACGGCAGTG ACAGTGAAAG CAGCTCTGCC
TCTTCCCCTC TCCATCACGA ACCCCCACCG CCATTATTGA AAACTAACAA CAACCAGATT
CTTGAAGTGA AAAGTCCAAT AAAACAAAGC AAATCAGATA AGCAAATAAA GAATGGTGAA
TGTGACAAGG CTTACCTAGA TGAGTTGGTA GAACTCCACA GAAGGTTAAT GACACTGAGG
GAAAGACACA TTCTGCAGCA GATCGTGAAC CTTATAGAGG AAACTGGACA CTTTCATATT
ACAAATACAA CATTTGATTT TGATCTTTGC TCGCTGGACA AAACTACAGT CCGTAAATTA
CAGAGTTACC TGGAGACATC TGGAACATCC TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_446170.1 CDS 335..1447 Translation 
Target ORF information:
RefSeq Version NM_053718.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus MLLT3, super elongation complex subunit (Mllt3), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_053718.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGAAGGAGC ACAAGGAAAA ACCTTCTAAG GACTCCAGAG AACATAAAAG TGCCTTCAAA
GAACCTTCCA GGGATCACAA CAAATCTTCC AAAGACTCCT CCAAGAAACC CAAAGAAAAC
AAACCACTGA AAGAAGAAAA AATCGTTCCT AAGATGGCCT TCAAGGAGCC TAAACCCATG
TCAAAAGAGC CAAAAGCAGA CAGTAACTTA CTCACCGTCA CCAGTGCACA GCAGGACAAG
AAGGCGCCTA GTAAAAGGCC CCCTGTTTCA GATTCTGAAG AACTCTCAGC CAAAAAAAGG
AAAAAGAGTA GCTCCGAGGC TTTATTTAAA AGTTTTTCTA GCGCGCCCCC ACTGATACTC
ACTTGTTCTG CTGACAAAAA ACAGATAAAA GATAAATCTC ATGTCAAGAT GGGAAAGGTC
AAAATCGAGA GCGAGACTTC AGAGAAGAAG AAGTCGACAC TGCCACCATT TGATGATATC
GTGGATCCCA ACGACTCAGA CGTGGAGGAG AACATGTCCT CAAAATCTGA CTCAGAGCAA
CCCAGTCCTG CCAGTTCCAG TTCCAGTTCC AGCTCCAGCT TCACGCCGTC TCAGACCAGG
CAGCAAGGTC CTTTAAGGTC GATCATGAAA GATCTGCATT CCGATGACAA CGAGGAGGAG
TCTGATGAGG CCGAGGACAA TGACAATGAC TCTGAGATGG AAAGGCCTGT AAACAGAGGG
GGAAGCCGAA GTCGCAGGGT CAGCTTGAGT GACGGCAGTG ACAGTGAAAG CAGCTCTGCC
TCTTCCCCTC TCCATCACGA ACCCCCACCG CCATTATTGA AAACTAACAA CAACCAGATT
CTTGAAGTGA AAAGTCCAAT AAAACAAAGC AAATCAGATA AGCAAATAAA GAATGGTGAA
TGTGACAAGG CTTACCTAGA TGAGTTGGTA GAACTCCACA GAAGGTTAAT GACACTGAGG
GAAAGACACA TTCTGCAGCA GATCGTGAAC CTTATAGAGG AAACTGGACA CTTTCATATT
ACAAATACAA CATTTGATTT TGATCTTTGC TCGCTGGACA AAACTACAGT CCGTAAATTA
CAGAGTTACC TGGAGACATC TGGAACATCC TGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure (London, England : 1993)24(9)1606-12(2016 09)
Zhang Q,Zeng L,Zhao C,Ju Y,Konuma T,Zhou MM
Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Molecular cell62(2)181-193(2016 04)
Li Y,Sabari BR,Panchenko T,Wen H,Zhao D,Guan H,Wan L,Huang H,Tang Z,Zhao Y,Roeder RG,Shi X,Allis CD,Li H
AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation.
Cell159(3)558-71(2014 Oct)
Li Y,Wen H,Xi Y,Tanaka K,Wang H,Peng D,Ren Y,Jin Q,Dent SY,Li W,Li H,Shi X
The super elongation complex (SEC) family in transcriptional control.
Nature reviews. Molecular cell biology13(9)543-7(2012 Sep)
Luo Z,Lin C,Shilatifard A
Spironolactone rescues Dot1a-Af9-mediated repression of endothelin-1 and improves kidney injury in streptozotocin-induced diabetic rats.
PloS one7(10)e47360(2012)
Zhou Q,Liu K,Wu H,Chen L,Pouranan V,Yuan M,Xiao Z,Peng W,Xiang A,Tang R,Zhang W
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