Dlst cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dlst
Entrez Gene ID	78920
Full Name	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Synonyms	1600017E01Rik,4632413C10Rik,4930529O08Rik,DLTS
General protein information	Preferred Names dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) Names dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 2-oxoglutarate dehydrogenase complex component E2 E2K OGDC-E2 dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 D1

mRNA and Protein(s)

mRNA	Protein	Name
XM_017315247.1	XP_017170736.1	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X2
NM_030225.4	NP_084501.1	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
XM_006516392.4	XP_006516455.1	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X1
XM_006516392.3	XP_006516455.1	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	DLST	NP_001924.2
Mus musculus (house mouse)	Dlst	NP_084501.1
Gallus gallus (chicken)	DLST	NP_001012919.1
Danio rerio (zebrafish)	dlst	NP_958895.1
Arabidopsis thaliana (thale cress)	AT5G55070	NP_200318.1
Eremothecium gossypii	AGOS_AGL200W	NP_986467.1
Neurospora crassa	NCU02438	XP_959443.1
Bos taurus (cattle)	DLST	NP_001068750.1
Caenorhabditis elegans (roundworm)	dlst-1	NP_504700.2
Xenopus tropicalis (tropical clawed frog)	dlst	NP_001004929.1
Magnaporthe oryzae (rice blast fungus)	MGG_03149	XP_003716846.1
Arabidopsis thaliana (thale cress)	AT4G26910	NP_567761.1
Canis lupus familiaris (dog)	DLST	XP_003639252.1
Pan troglodytes (chimpanzee)	DLST	XP_510068.2
Macaca mulatta (Rhesus monkey)	DLST	XP_001095138.1
Schizosaccharomyces pombe (fission yeast)	kgd2	NP_596331.1
Oryza sativa (rice)	Os04g0394200	NP_001052652.1
Rattus norvegicus (Norway rat)	Dlst	NP_001006982.2
Saccharomyces cerevisiae (baker's yeast)	KGD2	NP_010432.3
Kluyveromyces lactis	KLLA0D16522g	XP_453789.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004055	XP_309608.4

Gene Ontology
Bibliography

Related articles in PubMed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.
Malty RH, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, Minic Z, Goebels F, Musso G, Wu Z, Abou-Tok H, Meyer M, Deineko V, Kassir S, Sidhu V, Jessulat M, Scott NE, Xiong X, Vlasblom J, Prasad B, Foster LJ, Alberio T, Garavaglia B, Yu H, Bader GD, Nakamura K, Parkinson J, Babu M
Cell systems5(6)564-577.e12(2017 12)

Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.
Heggermont WA, Papageorgiou AP, Quaegebeur A, Deckx S, Carai P, Verhesen W, Eelen G, Schoors S, van Leeuwen R, Alekseev S, Elzenaar I, Vinckier S, Pokreisz P, Walravens AS, Gijsbers R, Van Den Haute C, Nickel A, Schroen B, van Bilsen M, Janssens S, Maack C, Pinto Y, Carmeliet P, Heymans S
Circulation136(8)747-761(2017 Aug)

Genetic modifications of Mecr reveal a role for mitochondrial 2-enoyl-CoA/ACP reductase in placental development in mice.
Nair RR, Kerätär JM, Autio KJ, Masud AJ, Finnilä MAJ, Autio-Harmainen HI, Miinalainen IJ, Nieminen PA, Hiltunen JK, Kastaniotis AJ
Human molecular genetics26(11)2104-2117(2017 06)

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A
Developmental cell40(4)331-341.e4(2017 02)

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Bowman CE, Zhao L, Hartung T, Wolfgang MJ
Molecular and cellular biology36(15)2089-104(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dlst gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dlst cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu48213	XM_006516392.4 Latest version!	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu78343	XM_017315247.1 Latest version!	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu13159	NM_030225.4 Latest version!	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OMu48213	XM_006516392.3	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dlst ( XM_006516392.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006516455.1 Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu48213
Clone ID Related Accession (Same CDS sequence)	XM_006516392.4 , XM_006516392.3
Accession Version	XM_006516392.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006516392.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC GGTCACGCTG CGTGTCCCGG GCGTTCAGCC GCTCGCTTTC TGCCTTCCAG 
AAGGGGAACT GCCCTCTAGG GAGACGTTCC CTGCCTGGGG TCTCCTTATG TCGGGGACCA 
GGTTACCCTG ACAACAGGAA GATGGTCATT AACAGTGGTA GCGTCTTCAG GGTTCGCTTC 
TTCCAAACCA CGGCTGTGTG CAAGAATGAT GTGATAACAG TCCAAACCCC AGCGTTTGCA 
GAGTCTGTCA CAGAGGGAGA TGTCAGGTGG GAGAAAGCTG TTGGAGATGC GGTTGCAGAA 
GATGAAGTGG TGTGTGAGAT TGAGACAGAC AAGACTTCTG TGCAGGTTCC GTCGCCAGCA 
AATGGCATCA TTGAAGCTCT TTTGGTACCC GATGGGGGCA AAGTTGAAGG AGGAACTCCT 
CTGTTCACAC TCAGGAAAAC TGCTGCTCCT GCTAAGGCCA AACCAGCTGA AACTCCTGCT 
CCAGCCCACA AAGCAGAGCC CGCAGCACCG GCGGCCCCTC CTCCCCCCGC AGCACCTGTG 
CTCACTCAGA TGCCACCAGT GCCCTCACCC TCACAGCCTC CTTCTAGCAA ACCAGTGTCT 
GCAATAAAAC CCACTGCTGC CCCTCCACTG GCTGAGGCAG GAGCTGCTAA AGGTCTGCGT 
TCAGAACATC GGGAGAAAAT GAACAGGATG CGGCAGCGCA TCGCCCAGCG TCTGAAGGAA 
GCCCAGAACA CGTGTGCAAT GCTGACGACT TTCAATGAGG TTGACATGAG TAACATACAA 
GAGATGAGAG CTCGGCACAA GGATGCTTTC CTGAAAAAAC ATAACCTCAA ATTAGGCTTC 
ATGTCAGCAT TTGTGAAGGC CTCGGCGTTC GCCTTGCAGG AGCAGCCTGT TGTAAATGCA 
GTGATTGATG ATGCAACCAA GGAAGTGGTG TATAGAGATT ATATTGACAT CAGTGTTGCA 
GTTGCTACCC CGAGGGGTCT CGTGGTTCCT GTCATCAGGA ATGTGGAAAC TATGAACTAT 
GCAGATATTG AACGGACCAT TAATGAACTA GGAGAGAAGG CCCGGAAGAA TGAACTTGCC 
ATTGAAGATA TGGATGGTGG TACCTTCACC ATCAGCAACG GAGGAGTTTT TGGCTCACTT 
TTTGGAACAC CCATTATCAA CCCCCCTCAA TCTGCCATCC TGGGCATGCA CGCCATCTTT 
GACAGGCCTG TGGCTGTGGG AGGCAAGGTG GAAGTTCGAC CTATGATGTA TGTAGCCCTG 
ACCTATGACC ACCGGCTGAT TGATGGCAGA GAGGCTGTGA CTTTCCTCCG AAAAATCAAG 
GCAGCAGTAG AAGATCCAAG AGTCCTCCTC CTAGACCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006516455.1
CDS	76..1437
Translation	MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCRGPGYPDNRKMVINSGSVFRVRFFQTTAVCKNDVITVQTPAFAESVTEGDVRWEKAVGDAVAEDEVVCEIETDKTSVQVPSPANGIIEALLVPDGGKVEGGTPLFTLRKTAAPAKAKPAETPAPAHKAEPAAPAAPPPPAAPVLTQMPPVPSPSQPPSSKPVSAIKPTAAPPLAEAGAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL

Target ORF information:

RefSeq Version	XM_006516392.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516392.4

ORF Insert Sequence:

ATGCTGTCCC GGTCACGCTG CGTGTCCCGG GCGTTCAGCC GCTCGCTTTC TGCCTTCCAG 
AAGGGGAACT GCCCTCTAGG GAGACGTTCC CTGCCTGGGG TCTCCTTATG TCGGGGACCA 
GGTTACCCTG ACAACAGGAA GATGGTCATT AACAGTGGTA GCGTCTTCAG GGTTCGCTTC 
TTCCAAACCA CGGCTGTGTG CAAGAATGAT GTGATAACAG TCCAAACCCC AGCGTTTGCA 
GAGTCTGTCA CAGAGGGAGA TGTCAGGTGG GAGAAAGCTG TTGGAGATGC GGTTGCAGAA 
GATGAAGTGG TGTGTGAGAT TGAGACAGAC AAGACTTCTG TGCAGGTTCC GTCGCCAGCA 
AATGGCATCA TTGAAGCTCT TTTGGTACCC GATGGGGGCA AAGTTGAAGG AGGAACTCCT 
CTGTTCACAC TCAGGAAAAC TGCTGCTCCT GCTAAGGCCA AACCAGCTGA AACTCCTGCT 
CCAGCCCACA AAGCAGAGCC CGCAGCACCG GCGGCCCCTC CTCCCCCCGC AGCACCTGTG 
CTCACTCAGA TGCCACCAGT GCCCTCACCC TCACAGCCTC CTTCTAGCAA ACCAGTGTCT 
GCAATAAAAC CCACTGCTGC CCCTCCACTG GCTGAGGCAG GAGCTGCTAA AGGTCTGCGT 
TCAGAACATC GGGAGAAAAT GAACAGGATG CGGCAGCGCA TCGCCCAGCG TCTGAAGGAA 
GCCCAGAACA CGTGTGCAAT GCTGACGACT TTCAATGAGG TTGACATGAG TAACATACAA 
GAGATGAGAG CTCGGCACAA GGATGCTTTC CTGAAAAAAC ATAACCTCAA ATTAGGCTTC 
ATGTCAGCAT TTGTGAAGGC CTCGGCGTTC GCCTTGCAGG AGCAGCCTGT TGTAAATGCA 
GTGATTGATG ATGCAACCAA GGAAGTGGTG TATAGAGATT ATATTGACAT CAGTGTTGCA 
GTTGCTACCC CGAGGGGTCT CGTGGTTCCT GTCATCAGGA ATGTGGAAAC TATGAACTAT 
GCAGATATTG AACGGACCAT TAATGAACTA GGAGAGAAGG CCCGGAAGAA TGAACTTGCC 
ATTGAAGATA TGGATGGTGG TACCTTCACC ATCAGCAACG GAGGAGTTTT TGGCTCACTT 
TTTGGAACAC CCATTATCAA CCCCCCTCAA TCTGCCATCC TGGGCATGCA CGCCATCTTT 
GACAGGCCTG TGGCTGTGGG AGGCAAGGTG GAAGTTCGAC CTATGATGTA TGTAGCCCTG 
ACCTATGACC ACCGGCTGAT TGATGGCAGA GAGGCTGTGA CTTTCCTCCG AAAAATCAAG 
GCAGCAGTAG AAGATCCAAG AGTCCTCCTC CTAGACCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dlst ( XM_006516392.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006516455.1 Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu48213
Clone ID Related Accession (Same CDS sequence)	XM_006516392.4 , XM_006516392.3
Accession Version	XM_006516392.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006516392.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCC GGTCACGCTG CGTGTCCCGG GCGTTCAGCC GCTCGCTTTC TGCCTTCCAG 
AAGGGGAACT GCCCTCTAGG GAGACGTTCC CTGCCTGGGG TCTCCTTATG TCGGGGACCA 
GGTTACCCTG ACAACAGGAA GATGGTCATT AACAGTGGTA GCGTCTTCAG GGTTCGCTTC 
TTCCAAACCA CGGCTGTGTG CAAGAATGAT GTGATAACAG TCCAAACCCC AGCGTTTGCA 
GAGTCTGTCA CAGAGGGAGA TGTCAGGTGG GAGAAAGCTG TTGGAGATGC GGTTGCAGAA 
GATGAAGTGG TGTGTGAGAT TGAGACAGAC AAGACTTCTG TGCAGGTTCC GTCGCCAGCA 
AATGGCATCA TTGAAGCTCT TTTGGTACCC GATGGGGGCA AAGTTGAAGG AGGAACTCCT 
CTGTTCACAC TCAGGAAAAC TGCTGCTCCT GCTAAGGCCA AACCAGCTGA AACTCCTGCT 
CCAGCCCACA AAGCAGAGCC CGCAGCACCG GCGGCCCCTC CTCCCCCCGC AGCACCTGTG 
CTCACTCAGA TGCCACCAGT GCCCTCACCC TCACAGCCTC CTTCTAGCAA ACCAGTGTCT 
GCAATAAAAC CCACTGCTGC CCCTCCACTG GCTGAGGCAG GAGCTGCTAA AGGTCTGCGT 
TCAGAACATC GGGAGAAAAT GAACAGGATG CGGCAGCGCA TCGCCCAGCG TCTGAAGGAA 
GCCCAGAACA CGTGTGCAAT GCTGACGACT TTCAATGAGG TTGACATGAG TAACATACAA 
GAGATGAGAG CTCGGCACAA GGATGCTTTC CTGAAAAAAC ATAACCTCAA ATTAGGCTTC 
ATGTCAGCAT TTGTGAAGGC CTCGGCGTTC GCCTTGCAGG AGCAGCCTGT TGTAAATGCA 
GTGATTGATG ATGCAACCAA GGAAGTGGTG TATAGAGATT ATATTGACAT CAGTGTTGCA 
GTTGCTACCC CGAGGGGTCT CGTGGTTCCT GTCATCAGGA ATGTGGAAAC TATGAACTAT 
GCAGATATTG AACGGACCAT TAATGAACTA GGAGAGAAGG CCCGGAAGAA TGAACTTGCC 
ATTGAAGATA TGGATGGTGG TACCTTCACC ATCAGCAACG GAGGAGTTTT TGGCTCACTT 
TTTGGAACAC CCATTATCAA CCCCCCTCAA TCTGCCATCC TGGGCATGCA CGCCATCTTT 
GACAGGCCTG TGGCTGTGGG AGGCAAGGTG GAAGTTCGAC CTATGATGTA TGTAGCCCTG 
ACCTATGACC ACCGGCTGAT TGATGGCAGA GAGGCTGTGA CTTTCCTCCG AAAAATCAAG 
GCAGCAGTAG AAGATCCAAG AGTCCTCCTC CTAGACCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006516455.1
CDS	77..1438
Translation	MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCRGPGYPDNRKMVINSGSVFRVRFFQTTAVCKNDVITVQTPAFAESVTEGDVRWEKAVGDAVAEDEVVCEIETDKTSVQVPSPANGIIEALLVPDGGKVEGGTPLFTLRKTAAPAKAKPAETPAPAHKAEPAAPAAPPPPAAPVLTQMPPVPSPSQPPSSKPVSAIKPTAAPPLAEAGAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL

Target ORF information:

RefSeq Version	XM_006516392.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516392.3

ORF Insert Sequence:

ATGCTGTCCC GGTCACGCTG CGTGTCCCGG GCGTTCAGCC GCTCGCTTTC TGCCTTCCAG 
AAGGGGAACT GCCCTCTAGG GAGACGTTCC CTGCCTGGGG TCTCCTTATG TCGGGGACCA 
GGTTACCCTG ACAACAGGAA GATGGTCATT AACAGTGGTA GCGTCTTCAG GGTTCGCTTC 
TTCCAAACCA CGGCTGTGTG CAAGAATGAT GTGATAACAG TCCAAACCCC AGCGTTTGCA 
GAGTCTGTCA CAGAGGGAGA TGTCAGGTGG GAGAAAGCTG TTGGAGATGC GGTTGCAGAA 
GATGAAGTGG TGTGTGAGAT TGAGACAGAC AAGACTTCTG TGCAGGTTCC GTCGCCAGCA 
AATGGCATCA TTGAAGCTCT TTTGGTACCC GATGGGGGCA AAGTTGAAGG AGGAACTCCT 
CTGTTCACAC TCAGGAAAAC TGCTGCTCCT GCTAAGGCCA AACCAGCTGA AACTCCTGCT 
CCAGCCCACA AAGCAGAGCC CGCAGCACCG GCGGCCCCTC CTCCCCCCGC AGCACCTGTG 
CTCACTCAGA TGCCACCAGT GCCCTCACCC TCACAGCCTC CTTCTAGCAA ACCAGTGTCT 
GCAATAAAAC CCACTGCTGC CCCTCCACTG GCTGAGGCAG GAGCTGCTAA AGGTCTGCGT 
TCAGAACATC GGGAGAAAAT GAACAGGATG CGGCAGCGCA TCGCCCAGCG TCTGAAGGAA 
GCCCAGAACA CGTGTGCAAT GCTGACGACT TTCAATGAGG TTGACATGAG TAACATACAA 
GAGATGAGAG CTCGGCACAA GGATGCTTTC CTGAAAAAAC ATAACCTCAA ATTAGGCTTC 
ATGTCAGCAT TTGTGAAGGC CTCGGCGTTC GCCTTGCAGG AGCAGCCTGT TGTAAATGCA 
GTGATTGATG ATGCAACCAA GGAAGTGGTG TATAGAGATT ATATTGACAT CAGTGTTGCA 
GTTGCTACCC CGAGGGGTCT CGTGGTTCCT GTCATCAGGA ATGTGGAAAC TATGAACTAT 
GCAGATATTG AACGGACCAT TAATGAACTA GGAGAGAAGG CCCGGAAGAA TGAACTTGCC 
ATTGAAGATA TGGATGGTGG TACCTTCACC ATCAGCAACG GAGGAGTTTT TGGCTCACTT 
TTTGGAACAC CCATTATCAA CCCCCCTCAA TCTGCCATCC TGGGCATGCA CGCCATCTTT 
GACAGGCCTG TGGCTGTGGG AGGCAAGGTG GAAGTTCGAC CTATGATGTA TGTAGCCCTG 
ACCTATGACC ACCGGCTGAT TGATGGCAGA GAGGCTGTGA CTTTCCTCCG AAAAATCAAG 
GCAGCAGTAG AAGATCCAAG AGTCCTCCTC CTAGACCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dlst ( XM_017315247.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017170736.1 Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu78343
Clone ID Related Accession (Same CDS sequence)	XM_017315247.1
Accession Version	XM_017315247.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCACCAG TGCCCTCACC CTCACAGCCT CCTTCTAGCA AACCAGTGTC TGCAATAAAA 
CCCACTGCTG CCCCTCCACT GGCTGAGGCA GGAGCTGCTA AAGGTCTGCG TTCAGAACAT 
CGGGAGAAAA TGAACAGGAT GCGGCAGCGC ATCGCCCAGC GTCTGAAGGA AGCCCAGAAC 
ACGTGTGCAA TGCTGACGAC TTTCAATGAG GTTGACATGA GTAACATACA AGAGATGAGA 
GCTCGGCACA AGGATGCTTT CCTGAAAAAA CATAACCTCA AATTAGGCTT CATGTCAGCA 
TTTGTGAAGG CCTCGGCGTT CGCCTTGCAG GAGCAGCCTG TTGTAAATGC AGTGATTGAT 
GATGCAACCA AGGAAGTGGT GTATAGAGAT TATATTGACA TCAGTGTTGC AGTTGCTACC 
CCGAGGGGTC TCGTGGTTCC TGTCATCAGG AATGTGGAAA CTATGAACTA TGCAGATATT 
GAACGGACCA TTAATGAACT AGGAGAGAAG GCCCGGAAGA ATGAACTTGC CATTGAAGAT 
ATGGATGGTG GTACCTTCAC CATCAGCAAC GGAGGAGTTT TTGGCTCACT TTTTGGAACA 
CCCATTATCA ACCCCCCTCA ATCTGCCATC CTGGGCATGC ACGCCATCTT TGACAGGCCT 
GTGGCTGTGG GAGGCAAGGT GGAAGTTCGA CCTATGATGT ATGTAGCCCT GACCTATGAC 
CACCGGCTGA TTGATGGCAG AGAGGCTGTG ACTTTCCTCC GAAAAATCAA GGCAGCAGTA 
GAAGATCCAA GAGTCCTCCT CCTAGACCTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017170736.1
CDS	662..1474
Translation	MPPVPSPSQPPSSKPVSAIKPTAAPPLAEAGAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL

Target ORF information:

RefSeq Version	XM_017315247.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017315247.1

ORF Insert Sequence:

ATGCCACCAG TGCCCTCACC CTCACAGCCT CCTTCTAGCA AACCAGTGTC TGCAATAAAA 
CCCACTGCTG CCCCTCCACT GGCTGAGGCA GGAGCTGCTA AAGGTCTGCG TTCAGAACAT 
CGGGAGAAAA TGAACAGGAT GCGGCAGCGC ATCGCCCAGC GTCTGAAGGA AGCCCAGAAC 
ACGTGTGCAA TGCTGACGAC TTTCAATGAG GTTGACATGA GTAACATACA AGAGATGAGA 
GCTCGGCACA AGGATGCTTT CCTGAAAAAA CATAACCTCA AATTAGGCTT CATGTCAGCA 
TTTGTGAAGG CCTCGGCGTT CGCCTTGCAG GAGCAGCCTG TTGTAAATGC AGTGATTGAT 
GATGCAACCA AGGAAGTGGT GTATAGAGAT TATATTGACA TCAGTGTTGC AGTTGCTACC 
CCGAGGGGTC TCGTGGTTCC TGTCATCAGG AATGTGGAAA CTATGAACTA TGCAGATATT 
GAACGGACCA TTAATGAACT AGGAGAGAAG GCCCGGAAGA ATGAACTTGC CATTGAAGAT 
ATGGATGGTG GTACCTTCAC CATCAGCAAC GGAGGAGTTT TTGGCTCACT TTTTGGAACA 
CCCATTATCA ACCCCCCTCA ATCTGCCATC CTGGGCATGC ACGCCATCTT TGACAGGCCT 
GTGGCTGTGG GAGGCAAGGT GGAAGTTCGA CCTATGATGT ATGTAGCCCT GACCTATGAC 
CACCGGCTGA TTGATGGCAG AGAGGCTGTG ACTTTCCTCC GAAAAATCAA GGCAGCAGTA 
GAAGATCCAA GAGTCCTCCT CCTAGACCTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dlst ( NM_030225.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084501.1 Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), mRNA.

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CloneID	OMu13159
Clone ID Related Accession (Same CDS sequence)	NM_030225.4
Accession Version	NM_030225.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573747200000
Organism	Mus musculus(house mouse)
Product	dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK158877.1, AK168570.1 and CJ308553.1. On Aug 5, 2009 this sequence version replaced NM_030225.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK158877.1, AK149664.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGCTGTCCC GGTCACGCTG CGTGTCCCGG GCGTTCAGCC GCTCGCTTTC TGCCTTCCAG 
AAGGGGAACT GCCCTCTAGG GAGACGTTCC CTGCCTGGGG TCTCCTTATG TCGGGGACCA 
GGTTACCCTG ACAACAGGAA GATGGTCATT AACAGTGGTA GCGTCTTCAG GGTTCGCTTC 
TTCCAAACCA CGGCTGTGTG CAAGAATGAT GTGATAACAG TCCAAACCCC AGCGTTTGCA 
GAGTCTGTCA CAGAGGGAGA TGTCAGGTGG GAGAAAGCTG TTGGAGATGC GGTTGCAGAA 
GATGAAGTGG TGTGTGAGAT TGAGACAGAC AAGACTTCTG TGCAGGTTCC GTCGCCAGCA 
AATGGCATCA TTGAAGCTCT TTTGGTACCC GATGGGGGCA AAGTTGAAGG AGGAACTCCT 
CTGTTCACAC TCAGGAAAAC TGGTGCTGCT CCTGCTAAGG CCAAACCAGC TGAAACTCCT 
GCTCCAGCCC ACAAAGCAGA GCCCGCAGCA CCGGCGGCCC CTCCTCCCCC CGCAGCACCT 
GTGCTCACTC AGATGCCACC AGTGCCCTCA CCCTCACAGC CTCCTTCTAG CAAACCAGTG 
TCTGCAATAA AACCCACTGC TGCCCCTCCA CTGGCTGAGG CAGGAGCTGC TAAAGGTCTG 
CGTTCAGAAC ATCGGGAGAA AATGAACAGG ATGCGGCAGC GCATCGCCCA GCGTCTGAAG 
GAAGCCCAGA ACACGTGTGC AATGCTGACG ACTTTCAATG AGGTTGACAT GAGTAACATA 
CAAGAGATGA GAGCTCGGCA CAAGGATGCT TTCCTGAAAA AACATAACCT CAAATTAGGC 
TTCATGTCAG CATTTGTGAA GGCCTCGGCG TTCGCCTTGC AGGAGCAGCC TGTTGTAAAT 
GCAGTGATTG ATGATGCAAC CAAGGAAGTG GTGTATAGAG ATTATATTGA CATCAGTGTT 
GCAGTTGCTA CCCCGAGGGG TCTCGTGGTT CCTGTCATCA GGAATGTGGA AACTATGAAC 
TATGCAGATA TTGAACGGAC CATTAATGAA CTAGGAGAGA AGGCCCGGAA GAATGAACTT 
GCCATTGAAG ATATGGATGG TGGTACCTTC ACCATCAGCA ACGGAGGAGT TTTTGGCTCA 
CTTTTTGGAA CACCCATTAT CAACCCCCCT CAATCTGCCA TCCTGGGCAT GCACGCCATC 
TTTGACAGGC CTGTGGCTGT GGGAGGCAAG GTGGAAGTTC GACCTATGAT GTATGTAGCC 
CTGACCTATG ACCACCGGCT GATTGATGGC AGAGAGGCTG TGACTTTCCT CCGAAAAATC 
AAGGCAGCAG TAGAAGATCC AAGAGTCCTC CTCCTAGACC TTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084501.1
CDS	65..1429
Translation	MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCRGPGYPDNRKMVINSGSVFRVRFFQTTAVCKNDVITVQTPAFAESVTEGDVRWEKAVGDAVAEDEVVCEIETDKTSVQVPSPANGIIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAETPAPAHKAEPAAPAAPPPPAAPVLTQMPPVPSPSQPPSSKPVSAIKPTAAPPLAEAGAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL

Target ORF information:

RefSeq Version	NM_030225.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) (Dlst), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030225.4

ORF Insert Sequence:

ATGCTGTCCC GGTCACGCTG CGTGTCCCGG GCGTTCAGCC GCTCGCTTTC TGCCTTCCAG 
AAGGGGAACT GCCCTCTAGG GAGACGTTCC CTGCCTGGGG TCTCCTTATG TCGGGGACCA 
GGTTACCCTG ACAACAGGAA GATGGTCATT AACAGTGGTA GCGTCTTCAG GGTTCGCTTC 
TTCCAAACCA CGGCTGTGTG CAAGAATGAT GTGATAACAG TCCAAACCCC AGCGTTTGCA 
GAGTCTGTCA CAGAGGGAGA TGTCAGGTGG GAGAAAGCTG TTGGAGATGC GGTTGCAGAA 
GATGAAGTGG TGTGTGAGAT TGAGACAGAC AAGACTTCTG TGCAGGTTCC GTCGCCAGCA 
AATGGCATCA TTGAAGCTCT TTTGGTACCC GATGGGGGCA AAGTTGAAGG AGGAACTCCT 
CTGTTCACAC TCAGGAAAAC TGGTGCTGCT CCTGCTAAGG CCAAACCAGC TGAAACTCCT 
GCTCCAGCCC ACAAAGCAGA GCCCGCAGCA CCGGCGGCCC CTCCTCCCCC CGCAGCACCT 
GTGCTCACTC AGATGCCACC AGTGCCCTCA CCCTCACAGC CTCCTTCTAG CAAACCAGTG 
TCTGCAATAA AACCCACTGC TGCCCCTCCA CTGGCTGAGG CAGGAGCTGC TAAAGGTCTG 
CGTTCAGAAC ATCGGGAGAA AATGAACAGG ATGCGGCAGC GCATCGCCCA GCGTCTGAAG 
GAAGCCCAGA ACACGTGTGC AATGCTGACG ACTTTCAATG AGGTTGACAT GAGTAACATA 
CAAGAGATGA GAGCTCGGCA CAAGGATGCT TTCCTGAAAA AACATAACCT CAAATTAGGC 
TTCATGTCAG CATTTGTGAA GGCCTCGGCG TTCGCCTTGC AGGAGCAGCC TGTTGTAAAT 
GCAGTGATTG ATGATGCAAC CAAGGAAGTG GTGTATAGAG ATTATATTGA CATCAGTGTT 
GCAGTTGCTA CCCCGAGGGG TCTCGTGGTT CCTGTCATCA GGAATGTGGA AACTATGAAC 
TATGCAGATA TTGAACGGAC CATTAATGAA CTAGGAGAGA AGGCCCGGAA GAATGAACTT 
GCCATTGAAG ATATGGATGG TGGTACCTTC ACCATCAGCA ACGGAGGAGT TTTTGGCTCA 
CTTTTTGGAA CACCCATTAT CAACCCCCCT CAATCTGCCA TCCTGGGCAT GCACGCCATC 
TTTGACAGGC CTGTGGCTGT GGGAGGCAAG GTGGAAGTTC GACCTATGAT GTATGTAGCC 
CTGACCTATG ACCACCGGCT GATTGATGGC AGAGAGGCTG TGACTTTCCT CCGAAAAATC 
AAGGCAGCAG TAGAAGATCC AAGAGTCCTC CTCCTAGACC TTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.
Cell systems5(6)564-577.e12(2017 12)
Malty RH,Aoki H,Kumar A,Phanse S,Amin S,Zhang Q,Minic Z,Goebels F,Musso G,Wu Z,Abou-Tok H,Meyer M,Deineko V,Kassir S,Sidhu V,Jessulat M,Scott NE,Xiong X,Vlasblom J,Prasad B,Foster LJ,Alberio T,Garavaglia B,Yu H,Bader GD,Nakamura K,Parkinson J,Babu M

Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.
Circulation136(8)747-761(2017 Aug)
Heggermont WA,Papageorgiou AP,Quaegebeur A,Deckx S,Carai P,Verhesen W,Eelen G,Schoors S,van Leeuwen R,Alekseev S,Elzenaar I,Vinckier S,Pokreisz P,Walravens AS,Gijsbers R,Van Den Haute C,Nickel A,Schroen B,van Bilsen M,Janssens S,Maack C,Pinto Y,Carmeliet P,Heymans S

Genetic modifications of Mecr reveal a role for mitochondrial 2-enoyl-CoA/ACP reductase in placental development in mice.
Human molecular genetics26(11)2104-2117(2017 06)
Nair RR,Kerätär JM,Autio KJ,Masud AJ,Finnilä MAJ,Autio-Harmainen HI,Miinalainen IJ,Nieminen PA,Hiltunen JK,Kastaniotis AJ

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Developmental cell40(4)331-341.e4(2017 02)
Bulusu V,Prior N,Snaebjornsson MT,Kuehne A,Sonnen KF,Kress J,Stein F,Schultz C,Sauer U,Aulehla A

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Molecular and cellular biology36(15)2089-104(2016 08)
Bowman CE,Zhao L,Hartung T,Wolfgang MJ

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Dlst cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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