| Gene Symbol | Plpp3 |
| Entrez Gene ID | 67916 |
| Full Name | phospholipid phosphatase 3 |
| Synonyms | 1110003O22Rik,2610002D05Rik,AV025606,D4Bwg0538e,D4Bwg1535e,Lpp3,Ppab2b,Ppap2b |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
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Plpp3 cDNA ORF clone, Mus musculus(house mouse)
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Gene
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Clones
gRNAs
The following Plpp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plpp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OMu22631 Clone ID Related Accession (Same CDS sequence) NM_080555.2 Accession Version NM_080555.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 939bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1562256000000 Organism Mus musculus(house mouse) Product phospholipid phosphatase 3 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY129827.1, AK160056.1, AK159136.1 and AV018880.1. On Feb 1, 2006 this sequence version replaced NM_080555.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK159136.1, SRR1660815.189997.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGCAAAGCT ACAAGTACGA CAAGGCGATC GTCCCTGAGA GTAAGAACGG CGGCAGCCCG
GCGCTCAACA ACAACCCGAG GAAGGGCGGC AGCAAGCGGG TGCTGCTCAT CTGCCTGGAC
CTCTTCTGCC TCTTCATGGC GGCTCTGCCC TTCCTCATCA TCGAGACAAG CACCATTAAG
CCTTACCGTC GAGGGTTTTA CTGCAATGAC GAGAGCATCA AGTATCCCCT GAAAGTCAGT
GAGACTATAA ACGATGCTGT GCTCTGTGCG GTGGGGATCG TCATCGCCAT CCTGGCGATC
ATTACAGGGG AATTCTACCG GATCTATTAC CTCAAGGAGA AGTCCCGCTC CACCACTCAG
AACCCGTATG TGGCAGCTCT CTATAAGCAA GTGGGATGCT TCCTTTTCGG CTGTGCCATT
AGCCAGTCCT TCACCGACAT CGCCAAAGTG TCCATCGGGC GCCTGAGGCC TCACTTCCTG
AGCGTCTGTG ACCCTGATTT CAGTCAGATC AATTGCTCCG AGGGCTACAT TCAGAACTAC
AGGTGCAGAG GAGAAGACAG CAAAGTACAG GAGGCCAGGA AGTCCTTCTT CTCGGGCCAC
GCCTCCTTCT CCATGTTCAC TATGCTGTAT CTGGTGCTCT ACCTTCAGGC CCGCTTCACC
TGGCGCGGGG CCCGACTGCT CCGCCCCCTC CTGCAGTTCA CTTTGCTCAT GATGGCCTTC
TACACGGGAT TGTCACGGGT ATCTGACTAC AAGCATCATC CTAGCGATGT CCTGGCAGGA
TTTGCCCAAG GAGCTCTGGT GGCCTGCTGC ATAGTGTTCT TCGTGTCCGA CCTCTTCAAG
ACTAAGACGA GCCTCTCACT GCCCGCCCCT GCGATCAGGA GGGAGATCCT GTCTCCCGTG
GACATCATCG ACAGGAACAA TCACCATAAC ATGGTGTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_542122.1 CDS 479..1417 Translation 
Target ORF information:
RefSeq Version NM_080555.2 Organism Mus musculus(house mouse) Definition Mus musculus phospholipid phosphatase 3 (Plpp3), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_080555.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901ATGCAAAGCT ACAAGTACGA CAAGGCGATC GTCCCTGAGA GTAAGAACGG CGGCAGCCCG
GCGCTCAACA ACAACCCGAG GAAGGGCGGC AGCAAGCGGG TGCTGCTCAT CTGCCTGGAC
CTCTTCTGCC TCTTCATGGC GGCTCTGCCC TTCCTCATCA TCGAGACAAG CACCATTAAG
CCTTACCGTC GAGGGTTTTA CTGCAATGAC GAGAGCATCA AGTATCCCCT GAAAGTCAGT
GAGACTATAA ACGATGCTGT GCTCTGTGCG GTGGGGATCG TCATCGCCAT CCTGGCGATC
ATTACAGGGG AATTCTACCG GATCTATTAC CTCAAGGAGA AGTCCCGCTC CACCACTCAG
AACCCGTATG TGGCAGCTCT CTATAAGCAA GTGGGATGCT TCCTTTTCGG CTGTGCCATT
AGCCAGTCCT TCACCGACAT CGCCAAAGTG TCCATCGGGC GCCTGAGGCC TCACTTCCTG
AGCGTCTGTG ACCCTGATTT CAGTCAGATC AATTGCTCCG AGGGCTACAT TCAGAACTAC
AGGTGCAGAG GAGAAGACAG CAAAGTACAG GAGGCCAGGA AGTCCTTCTT CTCGGGCCAC
GCCTCCTTCT CCATGTTCAC TATGCTGTAT CTGGTGCTCT ACCTTCAGGC CCGCTTCACC
TGGCGCGGGG CCCGACTGCT CCGCCCCCTC CTGCAGTTCA CTTTGCTCAT GATGGCCTTC
TACACGGGAT TGTCACGGGT ATCTGACTAC AAGCATCATC CTAGCGATGT CCTGGCAGGA
TTTGCCCAAG GAGCTCTGGT GGCCTGCTGC ATAGTGTTCT TCGTGTCCGA CCTCTTCAAG
ACTAAGACGA GCCTCTCACT GCCCGCCCCT GCGATCAGGA GGGAGATCCT GTCTCCCGTG
GACATCATCG ACAGGAACAA TCACCATAAC ATGGTGTAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Cardiac-specific inactivation of LPP3 in mice leads to myocardial dysfunction and heart failure.
Redox biology14261-271(2018 04)
Chandra M,Escalante-Alcalde D,Bhuiyan MS,Orr AW,Kevil C,Morris AJ,Nam H,Dominic P,McCarthy KJ,Miriyala S,Panchatcharam M
Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice.
PloS one13(6)e0198063(2018)
Federico L,Yang L,Brandon J,Panchatcharam M,Ren H,Mueller P,Sunkara M,Escalante-Alcalde D,Morris AJ,Smyth SS
Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE
Scientific reports744503(2017 03)
Busnelli M,Manzini S,Hilvo M,Parolini C,Ganzetti GS,Dellera F,Ekroos K,Jänis M,Escalante-Alcalde D,Sirtori CR,Laaksonen R,Chiesa G
Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.
Neuron92(1)126-142(2016 Oct)
Cheng J,Sahani S,Hausrat TJ,Yang JW,Ji H,Schmarowski N,Endle H,Liu X,Li Y,Böttche R,Radyushkin K,Maric HM,Hoerder-Suabedissen A,Molnár Z,Prouvot PH,Trimbuch T,Ninnemann O,Huai J,Fan W,Visentin B,Sabbadini R,Strømgaard K,Stroh A,Luhmann HJ,Kneussel M,Nitsch R,Vogt J
High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA
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