Polr2a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Polr2a
Entrez Gene ID	20020
Full Name	polymerase (RNA) II (DNA directed) polypeptide A
Synonyms	220kDa,Rpb1,Rpo2-1
General protein information	Preferred Names polymerase (RNA) II (DNA directed) polypeptide A Names DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit RNA polymerase II 1 RNA polymerase II subunit B1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 B3\|11 42.86 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001291068.1	NP_001277997.1	DNA-directed RNA polymerase II subunit RPB1

Pathways from BioSystems

Homologies

Schizosaccharomyces pombe (fission yeast)	rpb1	NP_595673.1
Pan troglodytes (chimpanzee)	POLR2A	XP_511300.3
Homo sapiens (human)	POLR2A	NP_000928.1
Neurospora crassa	NCU02103	XP_964097.1
Oryza sativa (rice)	Os05g0151000	NP_001054670.2
Canis lupus familiaris (dog)	POLR2A	XP_857844.2
Bos taurus (cattle)	POLR2A	NP_001193242.1
Rattus norvegicus (Norway rat)	Polr2a	XP_343923.3
Caenorhabditis elegans (roundworm)	ama-1	NP_500523.4
Xenopus tropicalis (tropical clawed frog)	polr2a	XP_002943327.2
Macaca mulatta (Rhesus monkey)	POLR2A	XP_001118060.2
Mus musculus (house mouse)	Polr2a	NP_033115.1
Saccharomyces cerevisiae (baker's yeast)	RPO21	NP_010141.1
Arabidopsis thaliana (thale cress)	NRPB1	NP_195305.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007810	XP_317690.3
Magnaporthe oryzae (rice blast fungus)	MGG_04652	XP_003713642.1
Kluyveromyces lactis	KLLA0F05071g	XP_455310.1
Danio rerio (zebrafish)	polr2a	XP_005156282.1
Drosophila melanogaster (fruit fly)	RpII215	NP_511124.1
Eremothecium gossypii	AGOS_ADR086C	NP_984182.2

Gene Ontology
Bibliography

Related articles in PubMed

Transitions in cell potency during early mouse development are driven by Notch.
Menchero S, Rollan I, Lopez-Izquierdo A, Andreu MJ, Sainz de Aja J, Kang M, Adan J, Benedito R, Rayon T, Hadjantonakis AK, Manzanares M
eLife8(2019 04)

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.
Celaya AM, Sánchez-Pérez I, Bermúdez-Muñoz JM, Rodríguez-de la Rosa L, Pintado-Berninches L, Perona R, Murillo-Cuesta S, Varela-Nieto I
eLife8(2019 04)

Chronic otitis media is initiated by a bulla cavitation defect in the FBXO11 mouse model.
Del-Pozo J, MacIntyre N, Azar A, Glover J, Milne E, Cheeseman M
Disease models & mechanisms12(3)(2019 03)

Repetitive Diffuse Mild Traumatic Brain Injury Causes an Atypical Astrocyte Response and Spontaneous Recurrent Seizures.
Shandra O, Winemiller AR, Heithoff BP, Munoz-Ballester C, George KK, Benko MJ, Zuidhoek IA, Besser MN, Curley DE, Edwards GF 3rd, Mey A, Harrington AN, Kitchen JP, Robel S
The Journal of neuroscience : the official journal of the Society for Neuroscience39(10)1944-1963(2019 Mar)

ENSA and ARPP19 differentially control cell cycle progression and development.
Hached K, Goguet P, Charrasse S, Vigneron S, Sacristan MP, Lorca T, Castro A
The Journal of cell biology218(2)541-558(2019 02)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Polr2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Polr2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20373	NM_001291068.1 Latest version!	Mus musculus polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Polr2a ( NM_001291068.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001277997.1 Mus musculus polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA.

Price & Availability↑

CloneID	OMu20373
Clone ID Related Accession (Same CDS sequence)	NM_001291068.1
Accession Version	NM_001291068.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5913bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	DNA-directed RNA polymerase II subunit RPB1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL603707.5. On Mar 22, 2014 this sequence version replaced XM_006532611.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U37500.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGCACGGGG GTGGCCCCCC CTCCGGGGAC AGCGCATGCC CGCTGCGCAC CATCAAGAGA 
GTGCAGTTCG GAGTCCTGAG TCCGGATGAA TTGAAGCGGA TGTCTGTGAC AGAGGGTGGT 
ATCAAATACC CAGAAACAAC GGAGGGAGGT CGCCCCAAAC TTGGGGGACT AATGGATCCA 
CGGCAGGGGG TGATTGAGCG GACTGGCCGC TGCCAAACAT GTGCAGGAAA CATGACCGAG 
TGTCCTGGCC ACTTTGGCCA CATCGAATTG GCCAAACCTG TGTTTCATGT GGGCTTCCTG 
GTGAAGACAA TGAAGGTTTT GCGCTGTGTC TGCTTCTTCT GCTCCAAACT GCTTGTAGAT 
TCTAATAACC CGAAGATTAA GGACATCCTG GCCAAATCTA AGGGGCAGCC AAAGAAACGG 
CTTACGCATG TCTATGACCT GTGCAAGGGC AAAAACATCT GTGAAGGTGG AGAGGAGATG 
GACAACAAGT TTGGTGTGGA GCAGCCGGAG GGTGATGAGG ATCTGACCAA AGAGAAGGGC 
CATGGCGGCT GTGGGCGGTA CCAACCCCGA ATCCGGCGCT CTGGCCTAGA GTTGTATGCT 
GAATGGAAGC ATGTTAATGA GGACTCTCAG GAGAAAAAGA TCTTGCTGAG TCCAGAACGA 
GTGCATGAAA TCTTCAAACG CATCTCAGAT GAGGAGTGTT TTGTGTTGGG CATGGAGCCT 
CGCTATGCCC GGCCTGAGTG GATGATTGTC ACAGTGTTGC CTGTGCCTCC TCTCTCAGTG 
AGACCTGCTG TGGTGATGCA GGGTTCTGCT CGAAACCAGG ATGATCTGAC TCACAAACTG 
GCTGACATTG TGAAGATCAA CAATCAGCTG CGGCGGAACG AGCAGAATGG TGCAGCTGCC 
CATGTCATAG CAGAAGATGT AAAACTTCTC CAGTTCCATG TGGCCACCAT GGTGGACAAT 
GAACTGCCCG GCTTACCCCG TGCCATGCAG AAGTCTGGCC GTCCCCTCAA GTCCCTGAAG 
CAACGGTTGA AGGGCAAAGA AGGACGGGTT CGAGGGAATC TAATGGGCAA GCGAGTGGAC 
TTCTCAGCCC GCACTGTCAT CACCCCTGAC CCTAACCTAT CCATTGACCA AGTGGGTGTG 
CCCCGCTCCA TTGCTGCCAA CATGACCTTT GCAGAGATTG TCACACCCTT CAATATTGAC 
AGACTTCAGG AATTAGTACG CAGGGGAAAC AGCCAGTATC CAGGAGCCAA GTACATCATC 
CGCGATAATG GCGATCGAAT TGACTTGCGT TTCCATCCTA AGCCCAGTGA CCTTCATCTG 
CAGACTGGCT ATAAGGTGGA ACGGCACATG TGTGATGGGG ACATTGTTAT CTTCAATCGT 
CAGCCAACTT TGCACAAAAT GTCCATGATG GGGCATCGGG TCCGAATCCT CCCCTGGTCT 
ACTTTTCGGT TGAATCTTAG TGTGACAACT CCATACAATG CAGACTTTGA TGGAGATGAG 
ATGAATTTGC ATCTGCCACA GTCTCTGGAA ACACGGGCAG AGATCCAAGA GTTGGCTATG 
GTGCCTCGAA TGATTGTCAC CCCCCAGAGC AATCGACCTG TCATGGGTAT TGTGCAAGAC 
ACACTCACGG CAGTACGCAA ATTCACTAAG AGAGATGTCT TCCTGGAGCG GGGTGAAGTC 
ATGAACCTCT TAATGTTTCT GTCCACGTGG GATGGCAAGG TCCCACAACC AGCTATCCTC 
AAGCCCCGGC CCCTGTGGAC AGGCAAGCAG ATCTTCTCCC TCATCATACC TGGACACATC 
AATTGTATCC GTACCCACAG CACCCATCCT GATGATGAAG ATAGTGGCCC TTACAAGCAC 
ATCTCTCCTG GGGACACCAA AGTTGTAGTG GAGAATGGGG AGCTTATCAT GGGCATCCTT 
TGTAAGAAGT CCCTGGGCAC CTCAGCAGGC TCGCTGGTCC ATATCTCCTA CCTGGAGATG 
GGGCATGACA TCACCCGCCT CTTCTACTCC AACATTCAGA CTGTCATTAA CAACTGGCTT 
CTCATCGAGG GTCATACCAT TGGCATTGGG GACTCCATTG CAGATTCAAA GACTTACCAG 
GACATTCAGA ACACTATTAA GAAAGCTAAA CAAGATGTAA TAGAGGTCAT TGAGAAGGCT 
CATAACAATG AGCTAGAACC CACTCCAGGA AACACATTGC GTCAGACATT TGAGAATCAA 
GTGAATCGTA TTCTCAATGA TGCTCGAGAC AAAACTGGCT CCTCTGCACA GAAATCCCTC 
TCTGAATATA ACAACTTCAA GTCTATGGTG GTGTCTGGAG CCAAGGGTTC CAAGATCAAC 
ATCTCCCAGG TCATTGCTGT TGTCGGGCAG CAGAATGTAG AGGGCAAGCG GATCCCATTT 
GGATTCAAGC ATCGGACTCT TCCTCACTTT ATCAAGGATG ATTATGGTCC TGAGAGCCGA 
GGCTTTGTAG AAAATTCATA CTTGGCTGGT CTCACACCCA CTGAGTTCTT CTTCCATGCC 
ATGGGAGGAC GAGAAGGTCT CATTGACACG GCTGTTAAGA CTGCTGAGAC TGGGTATATT 
CAGCGAAGGC TGATAAAGTC CATGGAGTCG GTGATGGTGA AATATGATGC AACTGTGAGG 
AACTCCATCA ACCAGGTGGT ACAGCTGCGC TATGGAGAGG ACGGCCTGGC AGGGGAGAGT 
GTTGAGTTCC AGAATCTGGC TACACTTAAA CCTTCTAATA AAGCTTTTGA GAAGAAGTTC 
CGTTTTGATT ATACCAATGA GAGGGCCCTG CGGCGCACCC TTCAGGAGGA CCTGGTAAAG 
GATGTGCTGA GCAATGCCCA TATACAGAAT GAGCTGGAAC GGGAATTTGA ACGGATGCGT 
GAAGATCGGG AAGTGCTCAG GGTCATCTTC CCAACTGGTG ACAGCAAGGT GGTCCTCCCT 
TGTAACCTTC TGCGGATGAT CTGGAATGCT CAGAAAATCT TCCACATCAA CCCTCGCCTT 
CCCTCTGACC TGCATCCCAT CAAAGTGGTA GAGGGAGTCA AAGAATTGAG CAAGAAGTTG 
GTAATTGTGA ATGGAGATGA CCCACTAAGT CGGCAGGCAC AGGAGAATGC CACATTGCTC 
TTCAACATCC ACCTAAGATC CACACTCTGC TCTCGCCGCA TGGCTGAGGA GTTTCGGCTG 
AGTGGAGAGG CCTTTGACTG GCTGCTTGGG GAGATAGAGT CCAAGTTCAA CCAAGCCATT 
GCCCATCCTG GAGAAATGGT GGGAGCTCTG GCTGCTCAGT CTCTTGGAGA ACCTGCCACT 
CAGATGACCC TGAACACTTT CCACTATGCT GGTGTATCTG CCAAGAATGT GACGCTGGGT 
GTGCCTCGAC TTAAGGAGCT TATCAACATT TCCAAGAAGC CAAAGACTCC TTCACTCACT 
GTCTTCCTGT TAGGTCAATC TGCACGAGAT GCTGAAAGAG CCAAGGACAT TCTTTGCCGC 
TTGGAACATA CAACATTGAG GAAGGTGACT GCCAATACAG CCATCTACTA TGACCCTAAC 
CCCCAGAGCA CAGTGGTGGC AGAAGATCAG GAGTGGGTGA ATGTGTACTA TGAGATGCCC 
GACTTTGACG TGGCCCGGAT ATCTCCCTGG CTGCTGCGTG TGGAGCTCGA CCGAAAGCAC 
ATGACTGACC GGAAGCTTAC CATGGAACAG ATTGCTGAGA AAATCAATGC AGGTTTTGGC 
GATGATTTGA ATTGTATCTT CAACGATGAT AATGCAGAGA AGCTGGTCCT TCGAATCCGC 
ATCATGAACA GTGATGAAAA CAAGATGCAA GAGGAGGAAG AGGTGGTGGA TAAAATGGAT 
GATGATGTCT TCCTGCGATG CATTGAGTCC AACATGCTGA CAGATATGAC CCTGCAGGGT 
ATCGAGCAGA TCAGCAAGGT GTACATGCAC TTACCTCAGA CAGACAACAA GAAGAAGATC 
ATCATCACAG AGGATGGGGA GTTCAAGGCC CTGCAGGAAT GGATCTTAGA GACGGATGGT 
GTGAGCCTGA TGCGGGTGCT GAGTGAGAAG GATGTAGACC CTGTGCGCAC CACGTCCAAT 
GATATTGTGG AGATCTTCAC GGTACTGGGC ATTGAGGCTG TGCGGAAGGC TCTGGAGCGA 
GAACTGTACC ATGTCATCTC CTTTGATGGT TCTTATGTCA ATTATCGGCA TTTGGCGCTC 
CTGTGTGACA CTATGACATG CCGTGGCCAC TTGATGGCCA TCACTCGTCA TGGGGTCAAC 
CGCCAGGACA CTGGACCGCT CATGAAATGC TCCTTTGAGG AAACGGTGGA TGTCCTTATG 
GAAGCAGCAG CACATGGGGA GAGTGACCCG ATGAAGGGAG TCTCTGAGAA TATTATGCTG 
GGCCAGCTCG CTCCAGCTGG TACTGGCTGT TTTGACCTCC TGCTTGATGC TGAGAAGTGC 
AAATACGGCA TGGAAATCCC CACCAATATC CCTGGCCTGG GGGCTGCTGG ACCTACCGGC 
ATGTTCTTTG GCTCTGCACC CAGTCCGATG GGAGGAATAT CTCCTGCAAT GACACCCTGG 
AACCAGGGTG CAACTCCCGC CTATGGTGCC TGGTCCCCGA GTGTTGGGAG CGGGATGACC 
CCAGGAGCGG CCGGCTTCTC TCCCAGTGCT GCATCTGATG CCAGTGGCTT CAGCCCAGGT 
TACTCCCCTG CATGGTCTCC CACACCAGGC TCTCCGGGCT CCCCTGGACC CTCAAGCCCA 
TACATCCCCT CACCAGGTGG TGCTATGTCT CCCAGCTACT CACCGACATC ACCAGCCTAT 
GAGCCACGCT CCCCTGGGGG CTATACACCC CAGAGCCCCT CCTACTCCCC TACTTCACCT 
TCCTACTCCC CAACCTCTCC ATCTTACTCT CCAACCAGTC CCAACTACAG CCCTACCTCT 
CCTAGCTACT CGCCCACCTC CCCTAGCTAC TCGCCAACCT CTCCTTCCTA CTCCCCCACC 
TCTCCAAGCT ATTCCCCAAC CTCTCCTAGC TACTCCCCAA CCTCTCCAAG CTATTCTCCA 
ACATCACCTA GCTATTCTCC AACTTCTCCC AGCTACTCAC CGACATCTCC TAGCTACTCC 
CCAACTTCTC CCAGCTACTC ACCAACTTCA CCAAGCTATT CTCCCACCTC CCCCAGCTAC 
TCACCGACAT CTCCCAGCTA CTCACCAACT TCTCCAAGCT ACTCACCAAC TTCTCCAAGC 
TACTCACCCA CCAGCCCTAA CTATTCTCCA ACTAGTCCCA ACTATACCCC GACATCACCC 
AGCTACAGCC CAACCTCACC CAGTTACTCA CCTACAAGTC CCAACTATAC ACCCACCAGC 
CCTAATTACA GCCCAACCTC TCCAAGCTAT TCCCCAACCT CACCCAGTTA TTCCCCCACC 
TCACCAAGCT ACTCCCCCTC CAGCCCACGA TATACACCAC AGTCTCCAAC CTACACACCA 
AGCTCACCAA GCTACAGTCC CAGCTCACCA AGCTACAGCC CCACTTCACC CAAGTACACC 
CCAACTAGTC CTTCCTACAG TCCCAGCTCA CCAGAGTACA CCCCAGCTTC TCCCAAATAC 
TCACCTACAA GCCCTAAATA TTCACCCACT TCTCCCAAGT ATTCTCCTAC CAGCCCCACT 
TACTCACCTA CCACCCCAAA ATATTCTCCA ACCTCCCCGA CATACTCACC AACCTCTCCA 
GTCTATACCC CGACCTCTCC CAAGTACTCC CCAACCAGCC CTACCTACTC GCCCACTTCT 
CCCAAGTACT CGCCCACCAG TCCCACCTAC TCACCCACCT CTCCCAAGGG CTCCACCTAC 
TCTCCCACTT CTCCTGGCTA CTCACCCACT AGCCCCACCT ACAGCCTCAC CAGCCCAGCC 
ATCAGCCCAG ATGACAGCGA TGAGGAGAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277997.1
CDS	411..6323
Translation	MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPASPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN

Target ORF information:

RefSeq Version	NM_001291068.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291068.1

ORF Insert Sequence:

ATGCACGGGG GTGGCCCCCC CTCCGGGGAC AGCGCATGCC CGCTGCGCAC CATCAAGAGA 
GTGCAGTTCG GAGTCCTGAG TCCGGATGAA TTGAAGCGGA TGTCTGTGAC AGAGGGTGGT 
ATCAAATACC CAGAAACAAC GGAGGGAGGT CGCCCCAAAC TTGGGGGACT AATGGATCCA 
CGGCAGGGGG TGATTGAGCG GACTGGCCGC TGCCAAACAT GTGCAGGAAA CATGACCGAG 
TGTCCTGGCC ACTTTGGCCA CATCGAATTG GCCAAACCTG TGTTTCATGT GGGCTTCCTG 
GTGAAGACAA TGAAGGTTTT GCGCTGTGTC TGCTTCTTCT GCTCCAAACT GCTTGTAGAT 
TCTAATAACC CGAAGATTAA GGACATCCTG GCCAAATCTA AGGGGCAGCC AAAGAAACGG 
CTTACGCATG TCTATGACCT GTGCAAGGGC AAAAACATCT GTGAAGGTGG AGAGGAGATG 
GACAACAAGT TTGGTGTGGA GCAGCCGGAG GGTGATGAGG ATCTGACCAA AGAGAAGGGC 
CATGGCGGCT GTGGGCGGTA CCAACCCCGA ATCCGGCGCT CTGGCCTAGA GTTGTATGCT 
GAATGGAAGC ATGTTAATGA GGACTCTCAG GAGAAAAAGA TCTTGCTGAG TCCAGAACGA 
GTGCATGAAA TCTTCAAACG CATCTCAGAT GAGGAGTGTT TTGTGTTGGG CATGGAGCCT 
CGCTATGCCC GGCCTGAGTG GATGATTGTC ACAGTGTTGC CTGTGCCTCC TCTCTCAGTG 
AGACCTGCTG TGGTGATGCA GGGTTCTGCT CGAAACCAGG ATGATCTGAC TCACAAACTG 
GCTGACATTG TGAAGATCAA CAATCAGCTG CGGCGGAACG AGCAGAATGG TGCAGCTGCC 
CATGTCATAG CAGAAGATGT AAAACTTCTC CAGTTCCATG TGGCCACCAT GGTGGACAAT 
GAACTGCCCG GCTTACCCCG TGCCATGCAG AAGTCTGGCC GTCCCCTCAA GTCCCTGAAG 
CAACGGTTGA AGGGCAAAGA AGGACGGGTT CGAGGGAATC TAATGGGCAA GCGAGTGGAC 
TTCTCAGCCC GCACTGTCAT CACCCCTGAC CCTAACCTAT CCATTGACCA AGTGGGTGTG 
CCCCGCTCCA TTGCTGCCAA CATGACCTTT GCAGAGATTG TCACACCCTT CAATATTGAC 
AGACTTCAGG AATTAGTACG CAGGGGAAAC AGCCAGTATC CAGGAGCCAA GTACATCATC 
CGCGATAATG GCGATCGAAT TGACTTGCGT TTCCATCCTA AGCCCAGTGA CCTTCATCTG 
CAGACTGGCT ATAAGGTGGA ACGGCACATG TGTGATGGGG ACATTGTTAT CTTCAATCGT 
CAGCCAACTT TGCACAAAAT GTCCATGATG GGGCATCGGG TCCGAATCCT CCCCTGGTCT 
ACTTTTCGGT TGAATCTTAG TGTGACAACT CCATACAATG CAGACTTTGA TGGAGATGAG 
ATGAATTTGC ATCTGCCACA GTCTCTGGAA ACACGGGCAG AGATCCAAGA GTTGGCTATG 
GTGCCTCGAA TGATTGTCAC CCCCCAGAGC AATCGACCTG TCATGGGTAT TGTGCAAGAC 
ACACTCACGG CAGTACGCAA ATTCACTAAG AGAGATGTCT TCCTGGAGCG GGGTGAAGTC 
ATGAACCTCT TAATGTTTCT GTCCACGTGG GATGGCAAGG TCCCACAACC AGCTATCCTC 
AAGCCCCGGC CCCTGTGGAC AGGCAAGCAG ATCTTCTCCC TCATCATACC TGGACACATC 
AATTGTATCC GTACCCACAG CACCCATCCT GATGATGAAG ATAGTGGCCC TTACAAGCAC 
ATCTCTCCTG GGGACACCAA AGTTGTAGTG GAGAATGGGG AGCTTATCAT GGGCATCCTT 
TGTAAGAAGT CCCTGGGCAC CTCAGCAGGC TCGCTGGTCC ATATCTCCTA CCTGGAGATG 
GGGCATGACA TCACCCGCCT CTTCTACTCC AACATTCAGA CTGTCATTAA CAACTGGCTT 
CTCATCGAGG GTCATACCAT TGGCATTGGG GACTCCATTG CAGATTCAAA GACTTACCAG 
GACATTCAGA ACACTATTAA GAAAGCTAAA CAAGATGTAA TAGAGGTCAT TGAGAAGGCT 
CATAACAATG AGCTAGAACC CACTCCAGGA AACACATTGC GTCAGACATT TGAGAATCAA 
GTGAATCGTA TTCTCAATGA TGCTCGAGAC AAAACTGGCT CCTCTGCACA GAAATCCCTC 
TCTGAATATA ACAACTTCAA GTCTATGGTG GTGTCTGGAG CCAAGGGTTC CAAGATCAAC 
ATCTCCCAGG TCATTGCTGT TGTCGGGCAG CAGAATGTAG AGGGCAAGCG GATCCCATTT 
GGATTCAAGC ATCGGACTCT TCCTCACTTT ATCAAGGATG ATTATGGTCC TGAGAGCCGA 
GGCTTTGTAG AAAATTCATA CTTGGCTGGT CTCACACCCA CTGAGTTCTT CTTCCATGCC 
ATGGGAGGAC GAGAAGGTCT CATTGACACG GCTGTTAAGA CTGCTGAGAC TGGGTATATT 
CAGCGAAGGC TGATAAAGTC CATGGAGTCG GTGATGGTGA AATATGATGC AACTGTGAGG 
AACTCCATCA ACCAGGTGGT ACAGCTGCGC TATGGAGAGG ACGGCCTGGC AGGGGAGAGT 
GTTGAGTTCC AGAATCTGGC TACACTTAAA CCTTCTAATA AAGCTTTTGA GAAGAAGTTC 
CGTTTTGATT ATACCAATGA GAGGGCCCTG CGGCGCACCC TTCAGGAGGA CCTGGTAAAG 
GATGTGCTGA GCAATGCCCA TATACAGAAT GAGCTGGAAC GGGAATTTGA ACGGATGCGT 
GAAGATCGGG AAGTGCTCAG GGTCATCTTC CCAACTGGTG ACAGCAAGGT GGTCCTCCCT 
TGTAACCTTC TGCGGATGAT CTGGAATGCT CAGAAAATCT TCCACATCAA CCCTCGCCTT 
CCCTCTGACC TGCATCCCAT CAAAGTGGTA GAGGGAGTCA AAGAATTGAG CAAGAAGTTG 
GTAATTGTGA ATGGAGATGA CCCACTAAGT CGGCAGGCAC AGGAGAATGC CACATTGCTC 
TTCAACATCC ACCTAAGATC CACACTCTGC TCTCGCCGCA TGGCTGAGGA GTTTCGGCTG 
AGTGGAGAGG CCTTTGACTG GCTGCTTGGG GAGATAGAGT CCAAGTTCAA CCAAGCCATT 
GCCCATCCTG GAGAAATGGT GGGAGCTCTG GCTGCTCAGT CTCTTGGAGA ACCTGCCACT 
CAGATGACCC TGAACACTTT CCACTATGCT GGTGTATCTG CCAAGAATGT GACGCTGGGT 
GTGCCTCGAC TTAAGGAGCT TATCAACATT TCCAAGAAGC CAAAGACTCC TTCACTCACT 
GTCTTCCTGT TAGGTCAATC TGCACGAGAT GCTGAAAGAG CCAAGGACAT TCTTTGCCGC 
TTGGAACATA CAACATTGAG GAAGGTGACT GCCAATACAG CCATCTACTA TGACCCTAAC 
CCCCAGAGCA CAGTGGTGGC AGAAGATCAG GAGTGGGTGA ATGTGTACTA TGAGATGCCC 
GACTTTGACG TGGCCCGGAT ATCTCCCTGG CTGCTGCGTG TGGAGCTCGA CCGAAAGCAC 
ATGACTGACC GGAAGCTTAC CATGGAACAG ATTGCTGAGA AAATCAATGC AGGTTTTGGC 
GATGATTTGA ATTGTATCTT CAACGATGAT AATGCAGAGA AGCTGGTCCT TCGAATCCGC 
ATCATGAACA GTGATGAAAA CAAGATGCAA GAGGAGGAAG AGGTGGTGGA TAAAATGGAT 
GATGATGTCT TCCTGCGATG CATTGAGTCC AACATGCTGA CAGATATGAC CCTGCAGGGT 
ATCGAGCAGA TCAGCAAGGT GTACATGCAC TTACCTCAGA CAGACAACAA GAAGAAGATC 
ATCATCACAG AGGATGGGGA GTTCAAGGCC CTGCAGGAAT GGATCTTAGA GACGGATGGT 
GTGAGCCTGA TGCGGGTGCT GAGTGAGAAG GATGTAGACC CTGTGCGCAC CACGTCCAAT 
GATATTGTGG AGATCTTCAC GGTACTGGGC ATTGAGGCTG TGCGGAAGGC TCTGGAGCGA 
GAACTGTACC ATGTCATCTC CTTTGATGGT TCTTATGTCA ATTATCGGCA TTTGGCGCTC 
CTGTGTGACA CTATGACATG CCGTGGCCAC TTGATGGCCA TCACTCGTCA TGGGGTCAAC 
CGCCAGGACA CTGGACCGCT CATGAAATGC TCCTTTGAGG AAACGGTGGA TGTCCTTATG 
GAAGCAGCAG CACATGGGGA GAGTGACCCG ATGAAGGGAG TCTCTGAGAA TATTATGCTG 
GGCCAGCTCG CTCCAGCTGG TACTGGCTGT TTTGACCTCC TGCTTGATGC TGAGAAGTGC 
AAATACGGCA TGGAAATCCC CACCAATATC CCTGGCCTGG GGGCTGCTGG ACCTACCGGC 
ATGTTCTTTG GCTCTGCACC CAGTCCGATG GGAGGAATAT CTCCTGCAAT GACACCCTGG 
AACCAGGGTG CAACTCCCGC CTATGGTGCC TGGTCCCCGA GTGTTGGGAG CGGGATGACC 
CCAGGAGCGG CCGGCTTCTC TCCCAGTGCT GCATCTGATG CCAGTGGCTT CAGCCCAGGT 
TACTCCCCTG CATGGTCTCC CACACCAGGC TCTCCGGGCT CCCCTGGACC CTCAAGCCCA 
TACATCCCCT CACCAGGTGG TGCTATGTCT CCCAGCTACT CACCGACATC ACCAGCCTAT 
GAGCCACGCT CCCCTGGGGG CTATACACCC CAGAGCCCCT CCTACTCCCC TACTTCACCT 
TCCTACTCCC CAACCTCTCC ATCTTACTCT CCAACCAGTC CCAACTACAG CCCTACCTCT 
CCTAGCTACT CGCCCACCTC CCCTAGCTAC TCGCCAACCT CTCCTTCCTA CTCCCCCACC 
TCTCCAAGCT ATTCCCCAAC CTCTCCTAGC TACTCCCCAA CCTCTCCAAG CTATTCTCCA 
ACATCACCTA GCTATTCTCC AACTTCTCCC AGCTACTCAC CGACATCTCC TAGCTACTCC 
CCAACTTCTC CCAGCTACTC ACCAACTTCA CCAAGCTATT CTCCCACCTC CCCCAGCTAC 
TCACCGACAT CTCCCAGCTA CTCACCAACT TCTCCAAGCT ACTCACCAAC TTCTCCAAGC 
TACTCACCCA CCAGCCCTAA CTATTCTCCA ACTAGTCCCA ACTATACCCC GACATCACCC 
AGCTACAGCC CAACCTCACC CAGTTACTCA CCTACAAGTC CCAACTATAC ACCCACCAGC 
CCTAATTACA GCCCAACCTC TCCAAGCTAT TCCCCAACCT CACCCAGTTA TTCCCCCACC 
TCACCAAGCT ACTCCCCCTC CAGCCCACGA TATACACCAC AGTCTCCAAC CTACACACCA 
AGCTCACCAA GCTACAGTCC CAGCTCACCA AGCTACAGCC CCACTTCACC CAAGTACACC 
CCAACTAGTC CTTCCTACAG TCCCAGCTCA CCAGAGTACA CCCCAGCTTC TCCCAAATAC 
TCACCTACAA GCCCTAAATA TTCACCCACT TCTCCCAAGT ATTCTCCTAC CAGCCCCACT 
TACTCACCTA CCACCCCAAA ATATTCTCCA ACCTCCCCGA CATACTCACC AACCTCTCCA 
GTCTATACCC CGACCTCTCC CAAGTACTCC CCAACCAGCC CTACCTACTC GCCCACTTCT 
CCCAAGTACT CGCCCACCAG TCCCACCTAC TCACCCACCT CTCCCAAGGG CTCCACCTAC 
TCTCCCACTT CTCCTGGCTA CTCACCCACT AGCCCCACCT ACAGCCTCAC CAGCCCAGCC 
ATCAGCCCAG ATGACAGCGA TGAGGAGAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transitions in cell potency during early mouse development are driven by Notch.
eLife8(2019 04)
Menchero S,Rollan I,Lopez-Izquierdo A,Andreu MJ,Sainz de Aja J,Kang M,Adan J,Benedito R,Rayon T,Hadjantonakis AK,Manzanares M

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.
eLife8(2019 04)
Celaya AM,Sánchez-Pérez I,Bermúdez-Muñoz JM,Rodríguez-de la Rosa L,Pintado-Berninches L,Perona R,Murillo-Cuesta S,Varela-Nieto I

Chronic otitis media is initiated by a bulla cavitation defect in the FBXO11 mouse model.
Disease models & mechanisms12(3)(2019 03)
Del-Pozo J,MacIntyre N,Azar A,Glover J,Milne E,Cheeseman M

Repetitive Diffuse Mild Traumatic Brain Injury Causes an Atypical Astrocyte Response and Spontaneous Recurrent Seizures.
The Journal of neuroscience : the official journal of the Society for Neuroscience39(10)1944-1963(2019 Mar)
Shandra O,Winemiller AR,Heithoff BP,Munoz-Ballester C,George KK,Benko MJ,Zuidhoek IA,Besser MN,Curley DE,Edwards GF 3rd,Mey A,Harrington AN,Kitchen JP,Robel S

ENSA and ARPP19 differentially control cell cycle progression and development.
The Journal of cell biology218(2)541-558(2019 02)
Hached K,Goguet P,Charrasse S,Vigneron S,Sacristan MP,Lorca T,Castro A

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Polr2a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM