Mcm2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mcm2
Entrez Gene ID	17216
Full Name	minichromosome maintenance complex component 2
Synonyms	AA959861,AW476101,BM28,CDCL1,Mcmd2,mKIAA0030
General protein information	Preferred Names minichromosome maintenance complex component 2 Names DNA replication licensing factor MCM2 mini chromosome maintenance deficient 2 minichromosome maintenance deficient 2 mitotin minichromosome maintenance protein 2 homolog nuclear protein BM28
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 D1

mRNA and Protein(s)

mRNA	Protein	Name
NM_008564.2	NP_032590.2	DNA replication licensing factor MCM2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MCM2	XP_516724.2
Macaca mulatta (Rhesus monkey)	MCM2	XP_001099580.2
Rattus norvegicus (Norway rat)	Mcm2	NP_001101343.2
Xenopus tropicalis (tropical clawed frog)	mcm2	NP_001006772.1
Kluyveromyces lactis	KLLA0F12584g	XP_455649.1
Oryza sativa (rice)	Os11g0484300	NP_001067910.1
Canis lupus familiaris (dog)	MCM2	XP_541736.3
Gallus gallus (chicken)	MCM2	NP_001006139.1
Drosophila melanogaster (fruit fly)	Mcm2	NP_477121.1
Arabidopsis thaliana (thale cress)	MCM2	NP_175112.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004275	XP_313198.5
Bos taurus (cattle)	MCM2	XP_002707828.1
Mus musculus (house mouse)	Mcm2	NP_032590.2
Caenorhabditis elegans (roundworm)	mcm-2	NP_001022416.1
Saccharomyces cerevisiae (baker's yeast)	MCM2	NP_009530.1
Magnaporthe oryzae (rice blast fungus)	MGG_08122	XP_003715082.1
Eremothecium gossypii	AGOS_AFR178W	NP_985725.1
Neurospora crassa	NCU04327	XP_960973.1
Homo sapiens (human)	MCM2	NP_004517.2
Danio rerio (zebrafish)	mcm2	NP_775364.1
Schizosaccharomyces pombe (fission yeast)	mcm2	NP_595477.1

Gene Ontology
Bibliography

Related articles in PubMed

Female-biased embryonic death from inflammation induced by genomic instability.
McNairn AJ, Chuang CH, Bloom JC, Wallace MD, Schimenti JC
Nature567(7746)105-108(2019 03)

MCM2 promotes symmetric inheritance of modified histones during DNA replication.
Petryk N, Dalby M, Wenger A, Stromme CB, Strandsby A, Andersson R, Groth A
Science (New York, N.Y.)361(6409)1389-1392(2018 09)

COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression.
Parisot J, Flore G, Bertacchi M, Studer M
Development (Cambridge, England)144(11)2045-2058(2017 06)

MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression.
Marinaro F, Marzi MJ, Hoffmann N, Amin H, Pelizzoli R, Niola F, Nicassio F, De Pietri Tonelli D
EMBO reports18(4)603-618(2017 04)

A Signature of Genomic Instability Resulting from Deficient Replication Licensing.
Pruitt SC, Qin M, Wang J, Kunnev D, Freeland A
PLoS genetics13(1)e1006547(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mcm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu02233	NM_008564.2 Latest version!	Mus musculus minichromosome maintenance complex component 2 (Mcm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mcm2 ( NM_008564.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032590.2 Mus musculus minichromosome maintenance complex component 2 (Mcm2), mRNA.

Price & Availability↑

CloneID	OMu02233
Clone ID Related Accession (Same CDS sequence)	NM_008564.2
Accession Version	NM_008564.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2715bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Mus musculus(house mouse)
Product	DNA replication licensing factor MCM2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY324067.1, AK129039.1 and CK378639.1. On Apr 5, 2008 this sequence version replaced NM_008564.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC055318.1, AK037751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164140 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAGT CTTCTGAGTC TCTCTCAGCA TCTAGCCCTG CCCGTCAGCG GCGCCGGATC 
AGTGATCCCC TCACCTCCAG CCCAGGCCGC AGCTCCAGAC GTGCTGACGC CCTGACCTCC 
AGCCCTGGCA GAGACCTCCC CCCATTTGAA GATGAGTCTG AGGGGCTGCT GGGCACAGAG 
GGGCCCATGG AGGAAGAAGA GGATGGAGAG GAACTCATTG GTGATGGCAT GGAGAGAGAC 
TACCGTCCCA TTCCGGAGCT CGATGTCTAC GAGGCCGAGG GATTGGCCCT GGATGATGAA 
GATGTGGAGG AGCTGACAGC CAGTCAGAGA GAGGCAGCTG AGCGGACCAT GAGGCAGCGG 
GACCGTGAGG CTGGCAGAGG CCTGGGACGC ATGCGCCGGG GGCTGCTCTA TGACAGCAGC 
GAGGAAGATG AGGAGCGGCC TGCCCGTAAG CGCCGCCACG TAGAACGCGC CACAGAGGAT 
GGCGAGGAGG ATGAAGAGAT GATCGAGAGT ATTGAGAATC TGGAGGACCT CAAGGGCCAC 
TCGGTGCGCG AGTGGGTGAG CATGGCAGGG CCCAGGCTGG AGATCCACCA CCGCTTCAAG 
AACTTCCTGC GCACCCACGT GGACAGCCAT GGCCACAACG TCTTCAAGGA GCGCATCAGT 
GATATGTGCA AAGAGAACCG TGAGAGTTTG GTGGTAAATT ATGAAGACCT GGCAGCCCGG 
GAGCACGTGT TGGCATACTT CCTGCCGGAA GCACCGGCTG AGTTGCTGCA GATCTTTGAC 
GAGGCTGCCC TGGAGGTCGT GTTGGCCATG TACCCTAAAT ATGACCGTAT CACCAACCAC 
ATCCATGTGC GCATCTCCCA CCTGCCTCTG GTGGAGGAGC TGCGTTCACT GAGGCAGTTG 
CACCTGAACC AGCTGATCCG TACCAGTGGC GTGGTGACCA GCTGCACCGG AGTCCTGCCC 
CAGCTCAGCA TGGTCAAGTA CAACTGTAGC AAGTGCAACT TTGTACTGGG GCCTTTCTGC 
CAGTCTCAGA ATCAGGAGGT GAAGCCTGGC TCCTGCCCTG AGTGCCAGTC TGCTGGGCCC 
TTTGAGATCA ACATGGAGGA GACCATCTAT CAGAACTACC AACGTATCCG CATCCAGGAG 
AGTCCCGGCA AGGTGGCGGC TGGCCGACTG CCCCGTTCCA AGGATGCCAT TCTCCTCGCT 
GATCTGGTGG ACAGCTGCAA GCCAGGGGAC GAGATAGAGC TGACCGGCAT TTACCATAAT 
AACTATGACG GCTCGCTTAA CACCGCCAAC GGCTTTCCAG TCTTTGCCAC TATTATCTTG 
GCCAACCATG TTGCCAAGAA GGACAACAAA GTAGCTGTGG GGGAGCTCAC CGATGAGGAC 
GTGAAGATGA TCACCGGTCT CTCCAAGGAT CAGCAAATTG GAGAGAAGAT CTTTGCCAGC 
ATTGCACCCT CCATCTATGG GCATGAAGAC ATCAAGAGAG GCCTGGCTCT GGCCCTGTTT 
GGAGGGGAGC CCAAGAACCC AGGTGGAAAG CACAAGGTTC GAGGTGACAT TAATGTGCTC 
TTGTGTGGGG ACCCTGGCAC AGCAAAGTCC CAATTCCTCA AATACATCGA GAAAGTGTCT 
AGCCGTGCCA TCTTCACCAC TGGCCAGGGT GCGTCAGCAG TGGGTCTCAC CGCGTACGTT 
CAGCGGCATC CCGTCAGCAG AGAGTGGACC TTAGAGGCGG GAGCCCTGGT TCTGGCTGAC 
CGGGGGGTGT GTCTCATTGA CGAGTTTGAC AAGATGAATG ACCAGGACAG GACCAGCATC 
CACGAGGCCA TGGAACAGCA AAGCATCTCC ATCTCCAAGG CTGGCATCGT TACCTCGCTG 
CAAGCCCGCT GCACTGTCAT AGCTGCTGCC AACCCCATAG GAGGCCGCTA CGACCCTTCA 
CTGACCTTCT CAGAGAATGT AGACCTCACA GAGCCCATCA TTTCCCGCTT TGATGTCCTG 
TGTGTGGTGA GGGACACTGT TGATCCAGTT CAGGATGAGA TGCTGGCCCG CTTTGTGGTT 
GGCAGCCACG TCAGACACCA CCCCAGTAAC AAGAAGGATG AAGGGTTGAC TAATGGTGGC 
ACCTTGGAGC CAGCCATGCC CAACACATAT GGCGTGGAGC CCCTGCCTCA GGAGGTGCTG 
AAGAAGTATA TCATCTATGC CAAGGAGAGG GTCCGCCCGA AGCTCAACCA GATGGACCAG 
GATAAAGTGG CCAGGATGTA CAGTGACCTG AGGAAGGAGT CCATGGCAAC GGGCAGCATT 
CCCATCACGG TGCGCCACAT CGAGTCCATG ATCCGCATGG CCGAGGCCCA TGCCCGCATG 
CACCTGCGGG ACTACGTGAT GGAAGACGAT GTCAACATGG CCATCCGAGT GATGATGGAG 
AGCTTCATTG ACACCCAGAA GTTCAGCGTC ATGCGGAGTA TGCGCAAGAC TTTTGCCCGG 
TATCTCTCCT TCCGGCGAGA TAACAATGAT CTGCTGCTCT TCATACTGAA GCAGTTGGTG 
GCTGAGCAGG TGACATATCA ACGCAACCGC TTTGGGGCCC AGCAGGACAC CATTGAAATA 
CCTGAGAAGG ATCTGATGGA CAAGGCCAGG CAGATCAATA TTCACAACCT CTCTGCCTTC 
TACGACAGCG ACCTCTTCAA ATTCAACAAG TTCAGCCGTG ACCTGAAACG CAAACTGATC 
CTACAGCAGT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032590.2
CDS	131..2845
Translation	MAESSESLSASSPARQRRRISDPLTSSPGRSSRRADALTSSPGRDLPPFEDESEGLLGTEGPMEEEEDGEELIGDGMERDYRPIPELDVYEAEGLALDDEDVEELTASQREAAERTMRQRDREAGRGLGRMRRGLLYDSSEEDEERPARKRRHVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITGLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTLEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMMESFIDTQKFSVMRSMRKTFARYLSFRRDNNDLLLFILKQLVAEQVTYQRNRFGAQQDTIEIPEKDLMDKARQINIHNLSAFYDSDLFKFNKFSRDLKRKLILQQF

Target ORF information:

RefSeq Version	NM_008564.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus minichromosome maintenance complex component 2 (Mcm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008564.2

ORF Insert Sequence:

ATGGCGGAGT CTTCTGAGTC TCTCTCAGCA TCTAGCCCTG CCCGTCAGCG GCGCCGGATC 
AGTGATCCCC TCACCTCCAG CCCAGGCCGC AGCTCCAGAC GTGCTGACGC CCTGACCTCC 
AGCCCTGGCA GAGACCTCCC CCCATTTGAA GATGAGTCTG AGGGGCTGCT GGGCACAGAG 
GGGCCCATGG AGGAAGAAGA GGATGGAGAG GAACTCATTG GTGATGGCAT GGAGAGAGAC 
TACCGTCCCA TTCCGGAGCT CGATGTCTAC GAGGCCGAGG GATTGGCCCT GGATGATGAA 
GATGTGGAGG AGCTGACAGC CAGTCAGAGA GAGGCAGCTG AGCGGACCAT GAGGCAGCGG 
GACCGTGAGG CTGGCAGAGG CCTGGGACGC ATGCGCCGGG GGCTGCTCTA TGACAGCAGC 
GAGGAAGATG AGGAGCGGCC TGCCCGTAAG CGCCGCCACG TAGAACGCGC CACAGAGGAT 
GGCGAGGAGG ATGAAGAGAT GATCGAGAGT ATTGAGAATC TGGAGGACCT CAAGGGCCAC 
TCGGTGCGCG AGTGGGTGAG CATGGCAGGG CCCAGGCTGG AGATCCACCA CCGCTTCAAG 
AACTTCCTGC GCACCCACGT GGACAGCCAT GGCCACAACG TCTTCAAGGA GCGCATCAGT 
GATATGTGCA AAGAGAACCG TGAGAGTTTG GTGGTAAATT ATGAAGACCT GGCAGCCCGG 
GAGCACGTGT TGGCATACTT CCTGCCGGAA GCACCGGCTG AGTTGCTGCA GATCTTTGAC 
GAGGCTGCCC TGGAGGTCGT GTTGGCCATG TACCCTAAAT ATGACCGTAT CACCAACCAC 
ATCCATGTGC GCATCTCCCA CCTGCCTCTG GTGGAGGAGC TGCGTTCACT GAGGCAGTTG 
CACCTGAACC AGCTGATCCG TACCAGTGGC GTGGTGACCA GCTGCACCGG AGTCCTGCCC 
CAGCTCAGCA TGGTCAAGTA CAACTGTAGC AAGTGCAACT TTGTACTGGG GCCTTTCTGC 
CAGTCTCAGA ATCAGGAGGT GAAGCCTGGC TCCTGCCCTG AGTGCCAGTC TGCTGGGCCC 
TTTGAGATCA ACATGGAGGA GACCATCTAT CAGAACTACC AACGTATCCG CATCCAGGAG 
AGTCCCGGCA AGGTGGCGGC TGGCCGACTG CCCCGTTCCA AGGATGCCAT TCTCCTCGCT 
GATCTGGTGG ACAGCTGCAA GCCAGGGGAC GAGATAGAGC TGACCGGCAT TTACCATAAT 
AACTATGACG GCTCGCTTAA CACCGCCAAC GGCTTTCCAG TCTTTGCCAC TATTATCTTG 
GCCAACCATG TTGCCAAGAA GGACAACAAA GTAGCTGTGG GGGAGCTCAC CGATGAGGAC 
GTGAAGATGA TCACCGGTCT CTCCAAGGAT CAGCAAATTG GAGAGAAGAT CTTTGCCAGC 
ATTGCACCCT CCATCTATGG GCATGAAGAC ATCAAGAGAG GCCTGGCTCT GGCCCTGTTT 
GGAGGGGAGC CCAAGAACCC AGGTGGAAAG CACAAGGTTC GAGGTGACAT TAATGTGCTC 
TTGTGTGGGG ACCCTGGCAC AGCAAAGTCC CAATTCCTCA AATACATCGA GAAAGTGTCT 
AGCCGTGCCA TCTTCACCAC TGGCCAGGGT GCGTCAGCAG TGGGTCTCAC CGCGTACGTT 
CAGCGGCATC CCGTCAGCAG AGAGTGGACC TTAGAGGCGG GAGCCCTGGT TCTGGCTGAC 
CGGGGGGTGT GTCTCATTGA CGAGTTTGAC AAGATGAATG ACCAGGACAG GACCAGCATC 
CACGAGGCCA TGGAACAGCA AAGCATCTCC ATCTCCAAGG CTGGCATCGT TACCTCGCTG 
CAAGCCCGCT GCACTGTCAT AGCTGCTGCC AACCCCATAG GAGGCCGCTA CGACCCTTCA 
CTGACCTTCT CAGAGAATGT AGACCTCACA GAGCCCATCA TTTCCCGCTT TGATGTCCTG 
TGTGTGGTGA GGGACACTGT TGATCCAGTT CAGGATGAGA TGCTGGCCCG CTTTGTGGTT 
GGCAGCCACG TCAGACACCA CCCCAGTAAC AAGAAGGATG AAGGGTTGAC TAATGGTGGC 
ACCTTGGAGC CAGCCATGCC CAACACATAT GGCGTGGAGC CCCTGCCTCA GGAGGTGCTG 
AAGAAGTATA TCATCTATGC CAAGGAGAGG GTCCGCCCGA AGCTCAACCA GATGGACCAG 
GATAAAGTGG CCAGGATGTA CAGTGACCTG AGGAAGGAGT CCATGGCAAC GGGCAGCATT 
CCCATCACGG TGCGCCACAT CGAGTCCATG ATCCGCATGG CCGAGGCCCA TGCCCGCATG 
CACCTGCGGG ACTACGTGAT GGAAGACGAT GTCAACATGG CCATCCGAGT GATGATGGAG 
AGCTTCATTG ACACCCAGAA GTTCAGCGTC ATGCGGAGTA TGCGCAAGAC TTTTGCCCGG 
TATCTCTCCT TCCGGCGAGA TAACAATGAT CTGCTGCTCT TCATACTGAA GCAGTTGGTG 
GCTGAGCAGG TGACATATCA ACGCAACCGC TTTGGGGCCC AGCAGGACAC CATTGAAATA 
CCTGAGAAGG ATCTGATGGA CAAGGCCAGG CAGATCAATA TTCACAACCT CTCTGCCTTC 
TACGACAGCG ACCTCTTCAA ATTCAACAAG TTCAGCCGTG ACCTGAAACG CAAACTGATC 
CTACAGCAGT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Female-biased embryonic death from inflammation induced by genomic instability.
Nature567(7746)105-108(2019 03)
McNairn AJ,Chuang CH,Bloom JC,Wallace MD,Schimenti JC

MCM2 promotes symmetric inheritance of modified histones during DNA replication.
Science (New York, N.Y.)361(6409)1389-1392(2018 09)
Petryk N,Dalby M,Wenger A,Stromme CB,Strandsby A,Andersson R,Groth A

COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression.
Development (Cambridge, England)144(11)2045-2058(2017 06)
Parisot J,Flore G,Bertacchi M,Studer M

MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression.
EMBO reports18(4)603-618(2017 04)
Marinaro F,Marzi MJ,Hoffmann N,Amin H,Pelizzoli R,Niola F,Nicassio F,De Pietri Tonelli D

A Signature of Genomic Instability Resulting from Deficient Replication Licensing.
PLoS genetics13(1)e1006547(2017 Jan)
Pruitt SC,Qin M,Wang J,Kunnev D,Freeland A

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Mcm2 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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