mcm2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	mcm2
Entrez Gene ID	192338
Full Name	minichromosome maintenance complex component 2
Synonyms	cb737,chunp6905
General protein information	Preferred Names minichromosome maintenance complex component 2 Names DNA replication licensing factor MCM2 MCM2 minichromosome maintenance deficient 2, mitotin
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_173257.2	NP_775364.2	DNA replication licensing factor MCM2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MCM2	XP_516724.2
Macaca mulatta (Rhesus monkey)	MCM2	XP_001099580.2
Rattus norvegicus (Norway rat)	Mcm2	NP_001101343.2
Xenopus tropicalis (tropical clawed frog)	mcm2	NP_001006772.1
Kluyveromyces lactis	KLLA0F12584g	XP_455649.1
Oryza sativa (rice)	Os11g0484300	NP_001067910.1
Canis lupus familiaris (dog)	MCM2	XP_541736.3
Gallus gallus (chicken)	MCM2	NP_001006139.1
Drosophila melanogaster (fruit fly)	Mcm2	NP_477121.1
Arabidopsis thaliana (thale cress)	MCM2	NP_175112.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004275	XP_313198.5
Bos taurus (cattle)	MCM2	XP_002707828.1
Mus musculus (house mouse)	Mcm2	NP_032590.2
Caenorhabditis elegans (roundworm)	mcm-2	NP_001022416.1
Saccharomyces cerevisiae (baker's yeast)	MCM2	NP_009530.1
Magnaporthe oryzae (rice blast fungus)	MGG_08122	XP_003715082.1
Eremothecium gossypii	AGOS_AFR178W	NP_985725.1
Neurospora crassa	NCU04327	XP_960973.1
Homo sapiens (human)	MCM2	NP_004517.2
Danio rerio (zebrafish)	mcm2	NP_775364.1
Schizosaccharomyces pombe (fission yeast)	mcm2	NP_595477.1

Gene Ontology
Bibliography

Related articles in PubMed

Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model.
Li Y, Agrawal I, Gong Z
Disease models & mechanisms12(10)(2019 10)

Resting cells rely on the DNA helicase component MCM2 to build cilia.
Casar Tena T, Maerz LD, Szafranski K, Groth M, Blätte TJ, Donow C, Matysik S, Walther P, Jeggo PA, Burkhalter MD, Philipp M
Nucleic acids research47(1)134-151(2019 01)

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo.
Wagner DE, Weinreb C, Collins ZM, Briggs JA, Megason SG, Klein AM
Science (New York, N.Y.)360(6392)981-987(2018 06)

Epigenetic Studies Point to DNA Replication/Repair Genes as a Basis for the Heritable Nature of Long Term Complications in Diabetes.
Leontovich AA, Intine RV, Sarras MP Jr
Journal of diabetes research20162860780(2016)

Telomerase Is Essential for Zebrafish Heart Regeneration.
Bednarek D, González-Rosa JM, Guzmán-Martínez G, Gutiérrez-Gutiérrez Ó, Aguado T, Sánchez-Ferrer C, Marques IJ, Galardi-Castilla M, de Diego I, Gómez MJ, Cortés A, Zapata A, Jiménez-Borreguero LJ, Mercader N, Flores I
Cell reports12(10)1691-703(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following mcm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mcm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa39563	NM_173257.2 Latest version!	Danio rerio minichromosome maintenance complex component 2 (mcm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

mcm2 ( NM_173257.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_775364.2 Danio rerio minichromosome maintenance complex component 2 (mcm2), mRNA.

Price & Availability↑

CloneID	ODa39563
Clone ID Related Accession (Same CDS sequence)	NM_173257.2
Accession Version	NM_173257.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2670bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575648000000
Organism	Danio rerio(zebrafish)
Product	DNA replication licensing factor MCM2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU467843.4 and EH588242.1. On Jun 25, 2015 this sequence version replaced NM_173257.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC048026.1, GDQH01006067.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGATT CCTCAGAGTC GTTCAACATG GCCACCAGCC CCACTCGAGG CTCTCGGCGG 
GGGGATCTGA CCTCCAGCCC TGGCAGAGAC CTTCCTCCAT TTGAGGATGA GTCTGAGGGA 
CTTCTGGGAG ACACTCTTCC TGATGAGGAG GATGATGATG GAGAGGAGCT GATTGGAGAC 
GCCATGGAGA GAGACTACCG TGTAATCCCA GAGCTGGACC GCTATGAAGC GGAGGGTCTG 
GATGAGGATG AAGATCTGAG TGAACTTTCA CCCAGCGCTC GTGCCGAGGC AGAAGCGGCG 
ATGAGGAGAC GCGACAGAGA ACAAGGCCTT GGCATGGGCC GCATCGGACG TGGACTCCTT 
TACGACAGTG AAGACGAGGA TGACAAACGG CCTACGAAGA GGCAGCGTGT CCTGGCAGAG 
AGAGCAGCCG AAGGTGGAGC GATGGAGGGT GAGGATGAAG AGATGATTGA AAGCATTGAG 
AACCTGGAGG ACATGAAGGG CCACACGGTG CGCGAGTGGG TTTCTATGGC CGCACCACGA 
CTGGAGATCT ACCACCGCTT CAAGAACTTC CTGCGCACGC ACGTGGATGA GCACGGACAT 
AATGTGTTTA AAGAGCGCAT CAGTGACATG TGCAAAGAAA ATAAGGAGAG TTTGCTGGTG 
AACTACGAAG AGCTGGCTTC CAGAGAGCAT GTGTTGGCGT ATTTTCTACC AGAAGCTCCT 
GCCGAAATGC TGAAGATTTT TGACGAAGCA GCGAAAGAAG TTGTTCTTGC CATGTACCCC 
AAATACGACC GAATCGCACA TGAAATCCAC GTCAGAATCG GTAACCTACC ATTGGTGGAG 
GAGCTTCGAT CACTCAGGCA ACTCCACTTG AATCAGCTGA TCCGCACTAG TGGTGTCGTG 
ACCAGCTGCA CTGGAGTTCT TCCTCAGCTT GGGATGGTCA AATACAACTG TAACAAGTGT 
AACTTTATTT TGGGGCCGTT CTTCCAGTCT CAGAACCAGG AGGTGAAGCC GGGCTCCTGT 
CCTGAGTGTC AGTCGCTCGG GCCCTTCGAG ATCAACATGG AACAGACGGT GTACCAGAAC 
TACCAGCGCA TCACCATTCA GGAGAGTCCT GGGAAAGTGG CTGCTGGTCG CCTGCCTCGA 
TCTAAAGACG CCATCCTGCT TGCAGACCTG GTGGACATGT GTAAACCCGG AGATGAGATC 
GAGCTCACTG GAATCTACCA CAACAACTAT GACGGCTCTC TCAACATGGC CAATGGTTTC 
CCCGTCTTCG CCACCGTGAT CTTAGCCAAT CACATCGCTC GAAAGGACGA GGGCGTGGCT 
GTGGCGGAGC TCACCGATGA AGACGTCAAA GCCATCGTTG CACTGTCCAA AGACGAGCGC 
ATTGGCGAAA GGATTTTCGC AAGTATTGGA CCCTCAATCT ACGCACACGA GGACATTAAA 
CGCGGTCTGG CACTTGCTCT GTTTGGTGGC GAAGCTAAAA ATCCAGGTGG GAAGCACAAG 
GTGCGTGGTG ATATAAACGT CCTCCTGTGT GGAGATCCCG GCACGGCTAA ATCTCAGTTC 
CTGAAGTACG TGGAGAAGGT GGCGAGTCGA GCGGTGTTCA CCACAGGACA GGGAGCCTCC 
GCTGTGGGTC TGACGGCTTA CGTGCAGCGG CATCCCGTCA GCCGAGAGTG GACGCTGGAG 
GCCGGAGCGT TAGTGCTGGC GGACAGAGGA GTGTGTCTTA TTGATGAGTT CGATAAGATG 
AACGATCAGG ACAGAACCAG CATCCACGAG GCGATGGAGC AGCAGAGCAT CTCCATTTCC 
AAAGCAGGAA TCGTGACTTC TCTCCAGGCC CGCTGCACCG TCATCGCTGC CGCCAATCCC 
ATCGGTGGAC GCTACGACCC GTCTCTAACG TTTTCAGAAA ACGTGGACCT GACGGAGCCC 
ATCATTTCTC GATTTGATGT TCTGTGTGTT GTAAGAGACA CTGTCGATCC TGTGCAGGAT 
GAAATGTTGG CTCGCTTTGT GGTCGGCAGC CACATCAAGC ATCACCCTAG CAACAAAGAA 
GGGGGCGTGG CTGGACTGGA GGAGGTGGTG CTTCCCAACA CATTCGACGT CCCACCGATC 
CCGCAGGAGT TGCTCCGCAA GTACATCATT TACGCTAAAG AGCGCGTGAG GCCCAAACTC 
AACCAGATGG ACCAGGACAA AGTGGCCCGC ATTTACAGCG ACCTACGAAA AGAGTCCATG 
GCTACAGGAA GTATCCCGAT TACTGTGCGT CACATCGAGT CTATGATCCG TATGGCCGAG 
GCTCACGCTC GCATGCATCT GCGCGACTAC GTGCTGGAGG ACGACGTCAA CATGGCCATC 
CGCGTCATGC TAGAGAGCTT CATCGACACG CAGAAGTTCA GTGTGATGAG GAGCATGAGA 
AAGACGTTCG CACGGTATCT GGCCTTCAGA CGAGACAACA ACGAGCTGCT ACTGTTCATC 
CTTAAGCAGC TGGTTTCTGA GCAGGTCTCA TATCAGCGCA ACCGTTACGG AGCCCAGCAG 
GACACCATCG AGATAGCAGA GAAAGACCTG GTGGACAAGG CTCGACAGAT CAACATCCAC 
AGCCTGTCTG CGTTTTACGA CAGCGATCTC TTCCGCTCAA ACAAATTCTC CCACGATGTC 
AAGAAGAAGC TCATCGTTCA GCAGTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775364.2
CDS	64..2733
Translation	MADSSESFNMATSPTRGSRRGDLTSSPGRDLPPFEDESEGLLGDTLPDEEDDDGEELIGDAMERDYRVIPELDRYEAEGLDEDEDLSELSPSARAEAEAAMRRRDREQGLGMGRIGRGLLYDSEDEDDKRPTKRQRVLAERAAEGGAMEGEDEEMIESIENLEDMKGHTVREWVSMAAPRLEIYHRFKNFLRTHVDEHGHNVFKERISDMCKENKESLLVNYEELASREHVLAYFLPEAPAEMLKIFDEAAKEVVLAMYPKYDRIAHEIHVRIGNLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLGMVKYNCNKCNFILGPFFQSQNQEVKPGSCPECQSLGPFEINMEQTVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDMCKPGDEIELTGIYHNNYDGSLNMANGFPVFATVILANHIARKDEGVAVAELTDEDVKAIVALSKDERIGERIFASIGPSIYAHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHIKHHPSNKEGGVAGLEEVVLPNTFDVPPIPQELLRKYIIYAKERVRPKLNQMDQDKVARIYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVLEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLAFRRDNNELLLFILKQLVSEQVSYQRNRYGAQQDTIEIAEKDLVDKARQINIHSLSAFYDSDLFRSNKFSHDVKKKLIVQQF

Target ORF information:

RefSeq Version	NM_173257.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio minichromosome maintenance complex component 2 (mcm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173257.2

ORF Insert Sequence:

ATGGCGGATT CCTCAGAGTC GTTCAACATG GCCACCAGCC CCACTCGAGG CTCTCGGCGG 
GGGGATCTGA CCTCCAGCCC TGGCAGAGAC CTTCCTCCAT TTGAGGATGA GTCTGAGGGA 
CTTCTGGGAG ACACTCTTCC TGATGAGGAG GATGATGATG GAGAGGAGCT GATTGGAGAC 
GCCATGGAGA GAGACTACCG TGTAATCCCA GAGCTGGACC GCTATGAAGC GGAGGGTCTG 
GATGAGGATG AAGATCTGAG TGAACTTTCA CCCAGCGCTC GTGCCGAGGC AGAAGCGGCG 
ATGAGGAGAC GCGACAGAGA ACAAGGCCTT GGCATGGGCC GCATCGGACG TGGACTCCTT 
TACGACAGTG AAGACGAGGA TGACAAACGG CCTACGAAGA GGCAGCGTGT CCTGGCAGAG 
AGAGCAGCCG AAGGTGGAGC GATGGAGGGT GAGGATGAAG AGATGATTGA AAGCATTGAG 
AACCTGGAGG ACATGAAGGG CCACACGGTG CGCGAGTGGG TTTCTATGGC CGCACCACGA 
CTGGAGATCT ACCACCGCTT CAAGAACTTC CTGCGCACGC ACGTGGATGA GCACGGACAT 
AATGTGTTTA AAGAGCGCAT CAGTGACATG TGCAAAGAAA ATAAGGAGAG TTTGCTGGTG 
AACTACGAAG AGCTGGCTTC CAGAGAGCAT GTGTTGGCGT ATTTTCTACC AGAAGCTCCT 
GCCGAAATGC TGAAGATTTT TGACGAAGCA GCGAAAGAAG TTGTTCTTGC CATGTACCCC 
AAATACGACC GAATCGCACA TGAAATCCAC GTCAGAATCG GTAACCTACC ATTGGTGGAG 
GAGCTTCGAT CACTCAGGCA ACTCCACTTG AATCAGCTGA TCCGCACTAG TGGTGTCGTG 
ACCAGCTGCA CTGGAGTTCT TCCTCAGCTT GGGATGGTCA AATACAACTG TAACAAGTGT 
AACTTTATTT TGGGGCCGTT CTTCCAGTCT CAGAACCAGG AGGTGAAGCC GGGCTCCTGT 
CCTGAGTGTC AGTCGCTCGG GCCCTTCGAG ATCAACATGG AACAGACGGT GTACCAGAAC 
TACCAGCGCA TCACCATTCA GGAGAGTCCT GGGAAAGTGG CTGCTGGTCG CCTGCCTCGA 
TCTAAAGACG CCATCCTGCT TGCAGACCTG GTGGACATGT GTAAACCCGG AGATGAGATC 
GAGCTCACTG GAATCTACCA CAACAACTAT GACGGCTCTC TCAACATGGC CAATGGTTTC 
CCCGTCTTCG CCACCGTGAT CTTAGCCAAT CACATCGCTC GAAAGGACGA GGGCGTGGCT 
GTGGCGGAGC TCACCGATGA AGACGTCAAA GCCATCGTTG CACTGTCCAA AGACGAGCGC 
ATTGGCGAAA GGATTTTCGC AAGTATTGGA CCCTCAATCT ACGCACACGA GGACATTAAA 
CGCGGTCTGG CACTTGCTCT GTTTGGTGGC GAAGCTAAAA ATCCAGGTGG GAAGCACAAG 
GTGCGTGGTG ATATAAACGT CCTCCTGTGT GGAGATCCCG GCACGGCTAA ATCTCAGTTC 
CTGAAGTACG TGGAGAAGGT GGCGAGTCGA GCGGTGTTCA CCACAGGACA GGGAGCCTCC 
GCTGTGGGTC TGACGGCTTA CGTGCAGCGG CATCCCGTCA GCCGAGAGTG GACGCTGGAG 
GCCGGAGCGT TAGTGCTGGC GGACAGAGGA GTGTGTCTTA TTGATGAGTT CGATAAGATG 
AACGATCAGG ACAGAACCAG CATCCACGAG GCGATGGAGC AGCAGAGCAT CTCCATTTCC 
AAAGCAGGAA TCGTGACTTC TCTCCAGGCC CGCTGCACCG TCATCGCTGC CGCCAATCCC 
ATCGGTGGAC GCTACGACCC GTCTCTAACG TTTTCAGAAA ACGTGGACCT GACGGAGCCC 
ATCATTTCTC GATTTGATGT TCTGTGTGTT GTAAGAGACA CTGTCGATCC TGTGCAGGAT 
GAAATGTTGG CTCGCTTTGT GGTCGGCAGC CACATCAAGC ATCACCCTAG CAACAAAGAA 
GGGGGCGTGG CTGGACTGGA GGAGGTGGTG CTTCCCAACA CATTCGACGT CCCACCGATC 
CCGCAGGAGT TGCTCCGCAA GTACATCATT TACGCTAAAG AGCGCGTGAG GCCCAAACTC 
AACCAGATGG ACCAGGACAA AGTGGCCCGC ATTTACAGCG ACCTACGAAA AGAGTCCATG 
GCTACAGGAA GTATCCCGAT TACTGTGCGT CACATCGAGT CTATGATCCG TATGGCCGAG 
GCTCACGCTC GCATGCATCT GCGCGACTAC GTGCTGGAGG ACGACGTCAA CATGGCCATC 
CGCGTCATGC TAGAGAGCTT CATCGACACG CAGAAGTTCA GTGTGATGAG GAGCATGAGA 
AAGACGTTCG CACGGTATCT GGCCTTCAGA CGAGACAACA ACGAGCTGCT ACTGTTCATC 
CTTAAGCAGC TGGTTTCTGA GCAGGTCTCA TATCAGCGCA ACCGTTACGG AGCCCAGCAG 
GACACCATCG AGATAGCAGA GAAAGACCTG GTGGACAAGG CTCGACAGAT CAACATCCAC 
AGCCTGTCTG CGTTTTACGA CAGCGATCTC TTCCGCTCAA ACAAATTCTC CCACGATGTC 
AAGAAGAAGC TCATCGTTCA GCAGTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model.
Disease models & mechanisms12(10)(2019 10)
Li Y,Agrawal I,Gong Z

Resting cells rely on the DNA helicase component MCM2 to build cilia.
Nucleic acids research47(1)134-151(2019 01)
Casar Tena T,Maerz LD,Szafranski K,Groth M,Blätte TJ,Donow C,Matysik S,Walther P,Jeggo PA,Burkhalter MD,Philipp M

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo.
Science (New York, N.Y.)360(6392)981-987(2018 06)
Wagner DE,Weinreb C,Collins ZM,Briggs JA,Megason SG,Klein AM

Epigenetic Studies Point to DNA Replication/Repair Genes as a Basis for the Heritable Nature of Long Term Complications in Diabetes.
Journal of diabetes research20162860780(2016)
Leontovich AA,Intine RV,Sarras MP Jr

Telomerase Is Essential for Zebrafish Heart Regeneration.
Cell reports12(10)1691-703(2015 Sep)
Bednarek D,González-Rosa JM,Guzmán-Martínez G,Gutiérrez-Gutiérrez Ó,Aguado T,Sánchez-Ferrer C,Marques IJ,Galardi-Castilla M,de Diego I,Gómez MJ,Cortés A,Zapata A,Jiménez-Borreguero LJ,Mercader N,Flores I

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

mcm2 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM