Fpr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fpr1
Entrez Gene ID	14293
Full Name	formyl peptide receptor 1
Synonyms	FPR,LXA4R,fMLF-R
General protein information	Preferred Names formyl peptide receptor 1 Names fMet-Leu-Phe receptor N-formyl peptide receptor N-formylpeptide chemoattractant receptor fMLP receptor lipoxin A4 receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17 A3.2\|17 10.63 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_013521.2	NP_038549.1	fMet-Leu-Phe receptor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	FPR1	XP_001116431.1
Pan troglodytes (chimpanzee)	FPR1	XP_512862.1
Homo sapiens (human)	FPR1	NP_002020.1
Rattus norvegicus (Norway rat)	Fpr1	NP_001099686.1
Mus musculus (house mouse)	Fpr1	NP_038549.1

Gene Ontology
Bibliography

Related articles in PubMed

FPR1 is the plague receptor on host immune cells.
Osei-Owusu P, Charlton TM, Kim HK, Missiakas D, Schneewind O
Nature574(7776)57-62(2019 10)

Microbiota-Produced
Wollam J, Riopel M, Xu YJ, Johnson AMF, Ofrecio JM, Ying W, El Ouarrat D, Chan LS, Han AW, Mahmood NA, Ryan CN, Lee YS, Watrous JD, Chordia MD, Pan D, Jain M, Olefsky JM
Diabetes68(7)1415-1426(2019 07)

Formyl peptide receptor-1 activation exerts a critical role for the dynamic plasticity of arteries via actin polymerization.
Wenceslau CF, McCarthy CG, Szasz T, Calmasini FB, Mamenko M, Webb RC
Pharmacological research141276-290(2019 03)

G-protein-coupled formyl peptide receptors play a dual role in neutrophil chemotaxis and bacterial phagocytosis.
Wen X, Xu X, Sun W, Chen K, Pan M, Wang JM, Bolland SM, Jin T
Molecular biology of the cell30(3)346-356(2019 02)

Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice.
Kim YE, Park WS, Ahn SY, Sung DK, Chang YS
PloS one13(10)e0206311(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fpr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fpr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16655	NM_013521.2 Latest version!	Mus musculus formyl peptide receptor 1 (Fpr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fpr1 ( NM_013521.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038549.1 Mus musculus formyl peptide receptor 1 (Fpr1), mRNA.

Price & Availability↑

CloneID	OMu16655
Clone ID Related Accession (Same CDS sequence)	NM_013521.2
Accession Version	NM_013521.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Mus musculus(house mouse)
Product	fMet-Leu-Phe receptor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY194974.1, BY750286.1, L22181.1, BY160621.1 and BX514917.1. On Jul 28, 2005 this sequence version replaced NM_013521.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK137714.1, BY750286.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACACCA ACATGTCTCT CCTCATGAAC AAGTCTGCAG TGAACCTCAT GAATGTATCT 
GGGAGTACTC AATCAGTATC TGCTGGCTAC ATCGTTCTGG ATGTCTTCTC ATATTTGATC 
TTTGCCGTCA CATTTGTCCT TGGGGTTCTG GGCAACGGGC TCGTGATCTG GGTGGCTGGT 
TTCCGCATGA AACACACTGT CACCACCATC TCTTACTTGA ACTTGGCCAT TGCTGACTTT 
TGCTTCACTT CCACTTTGCC ATTTTACATT GCCAGCATGG TCATGGGAGG ACATTGGCCA 
TTTGGTTGGT TCATGTGCAA ATTCATATAT ACTGTAATAG ACATAAACCT ATTTGGAAGT 
GTCTTCCTGA TTGCCCTCAT TGCACTGGAC CGCTGTATTT GTGTTCTGCA TCCAGTCTGG 
GCTCAGAACC ACCGCACTGT GAGCCTAGCC AAGAAGGTAA TCATCGTACC CTGGATTTGT 
GCATTTCTTC TTACATTGCC AGTTATCATT CGTTTGACCA CAGTCCCTAA TAGTAGACTT 
GGACCAGGGA AAACAGCCTG TACTTTCGAC TTCTCCCCCT GGACCAAAGA TCCTGTAGAG 
AAGAGGAAGG TGGCCGTCAC CATGCTCACT GTCAGAGGAA TCATCAGGTT CATCATTGGG 
TTCAGCACTC CCATGTCCAT TGTTGCCATT TGCTATGGGT TAATAACCAC TAAAATTCAC 
AGGCAGGGCC TGATCAAATC CAGCCGTCCT TTGCGGGTTC TCTCCTTTGT TGTGGCTGCC 
TTTTTCCTCT GCTGGTGCCC ATTTCAAGTA GTGGCCCTCA TATCCACAAT CCAAGTCCGT 
GAACGGTTGA AGAACATGAC TCCAGGCATT GTAACTGCTT TGAAAATCAC AAGCCCCTTG 
GCTTTCTTCA ACAGCTGCCT CAATCCAATG CTTTATGTCT TTATGGGCCA GGACTTCAGA 
GAAAGACTAA TCCACTCTTT ACCTGCCAGC CTAGAGAGGG CCCTGACTGA GGACTCAGCT 
CAGACCAGTG ATACAGGCAC CAATTTGGGG ACCAACTCTA CTTCCCTTTC TGAAAACACT 
TTAAATGCAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038549.1
CDS	69..1163
Translation	MDTNMSLLMNKSAVNLMNVSGSTQSVSAGYIVLDVFSYLIFAVTFVLGVLGNGLVIWVAGFRMKHTVTTISYLNLAIADFCFTSTLPFYIASMVMGGHWPFGWFMCKFIYTVIDINLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLAKKVIIVPWICAFLLTLPVIIRLTTVPNSRLGPGKTACTFDFSPWTKDPVEKRKVAVTMLTVRGIIRFIIGFSTPMSIVAICYGLITTKIHRQGLIKSSRPLRVLSFVVAAFFLCWCPFQVVALISTIQVRERLKNMTPGIVTALKITSPLAFFNSCLNPMLYVFMGQDFRERLIHSLPASLERALTEDSAQTSDTGTNLGTNSTSLSENTLNAM

Target ORF information:

RefSeq Version	NM_013521.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus formyl peptide receptor 1 (Fpr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013521.2

ORF Insert Sequence:

ATGGACACCA ACATGTCTCT CCTCATGAAC AAGTCTGCAG TGAACCTCAT GAATGTATCT 
GGGAGTACTC AATCAGTATC TGCTGGCTAC ATCGTTCTGG ATGTCTTCTC ATATTTGATC 
TTTGCCGTCA CATTTGTCCT TGGGGTTCTG GGCAACGGGC TCGTGATCTG GGTGGCTGGT 
TTCCGCATGA AACACACTGT CACCACCATC TCTTACTTGA ACTTGGCCAT TGCTGACTTT 
TGCTTCACTT CCACTTTGCC ATTTTACATT GCCAGCATGG TCATGGGAGG ACATTGGCCA 
TTTGGTTGGT TCATGTGCAA ATTCATATAT ACTGTAATAG ACATAAACCT ATTTGGAAGT 
GTCTTCCTGA TTGCCCTCAT TGCACTGGAC CGCTGTATTT GTGTTCTGCA TCCAGTCTGG 
GCTCAGAACC ACCGCACTGT GAGCCTAGCC AAGAAGGTAA TCATCGTACC CTGGATTTGT 
GCATTTCTTC TTACATTGCC AGTTATCATT CGTTTGACCA CAGTCCCTAA TAGTAGACTT 
GGACCAGGGA AAACAGCCTG TACTTTCGAC TTCTCCCCCT GGACCAAAGA TCCTGTAGAG 
AAGAGGAAGG TGGCCGTCAC CATGCTCACT GTCAGAGGAA TCATCAGGTT CATCATTGGG 
TTCAGCACTC CCATGTCCAT TGTTGCCATT TGCTATGGGT TAATAACCAC TAAAATTCAC 
AGGCAGGGCC TGATCAAATC CAGCCGTCCT TTGCGGGTTC TCTCCTTTGT TGTGGCTGCC 
TTTTTCCTCT GCTGGTGCCC ATTTCAAGTA GTGGCCCTCA TATCCACAAT CCAAGTCCGT 
GAACGGTTGA AGAACATGAC TCCAGGCATT GTAACTGCTT TGAAAATCAC AAGCCCCTTG 
GCTTTCTTCA ACAGCTGCCT CAATCCAATG CTTTATGTCT TTATGGGCCA GGACTTCAGA 
GAAAGACTAA TCCACTCTTT ACCTGCCAGC CTAGAGAGGG CCCTGACTGA GGACTCAGCT 
CAGACCAGTG ATACAGGCAC CAATTTGGGG ACCAACTCTA CTTCCCTTTC TGAAAACACT 
TTAAATGCAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

FPR1 is the plague receptor on host immune cells.
Nature574(7776)57-62(2019 10)
Osei-Owusu P,Charlton TM,Kim HK,Missiakas D,Schneewind O

Microbiota-Produced
Diabetes68(7)1415-1426(2019 07)
Wollam J,Riopel M,Xu YJ,Johnson AMF,Ofrecio JM,Ying W,El Ouarrat D,Chan LS,Han AW,Mahmood NA,Ryan CN,Lee YS,Watrous JD,Chordia MD,Pan D,Jain M,Olefsky JM

Formyl peptide receptor-1 activation exerts a critical role for the dynamic plasticity of arteries via actin polymerization.
Pharmacological research141276-290(2019 03)
Wenceslau CF,McCarthy CG,Szasz T,Calmasini FB,Mamenko M,Webb RC

G-protein-coupled formyl peptide receptors play a dual role in neutrophil chemotaxis and bacterial phagocytosis.
Molecular biology of the cell30(3)346-356(2019 02)
Wen X,Xu X,Sun W,Chen K,Pan M,Wang JM,Bolland SM,Jin T

Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice.
PloS one13(10)e0206311(2018)
Kim YE,Park WS,Ahn SY,Sung DK,Chang YS