FPR1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FPR1
Entrez Gene ID	2357
Full Name	formyl peptide receptor 1
Synonyms	FMLP,FPR
General protein information	Preferred Names formyl peptide receptor 1 Names fMet-Leu-Phe receptor N-formylpeptide chemoattractant receptor fMLP receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.41
Summary	This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010].
Disorder MIM:	136537

mRNA and Protein(s)

mRNA	Protein	Name
NM_001193306.1	NP_001180235.1	fMet-Leu-Phe receptor
NM_001193306.2	NP_001180235.1	fMet-Leu-Phe receptor
NM_002029.3	NP_002020.1	fMet-Leu-Phe receptor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	FPR1	XP_001116431.1
Pan troglodytes (chimpanzee)	FPR1	XP_512862.1
Homo sapiens (human)	FPR1	NP_002020.1
Rattus norvegicus (Norway rat)	Fpr1	NP_001099686.1
Mus musculus (house mouse)	Fpr1	NP_038549.1

Gene Ontology
Bibliography

Related articles in PubMed

FPR1 is the plague receptor on host immune cells.
Osei-Owusu P, Charlton TM, Kim HK, Missiakas D, Schneewind O
Nature574(7776)57-62(2019 10)

Inhibition of the AnxA1/FPR1 autocrine axis reduces MDA-MB-231 breast cancer cell growth and aggressiveness in vitro and in vivo.
Vecchi L, Alves Pereira Zóia M, Goss Santos T, de Oliveira Beserra A, Colaço Ramos CM, França Matias Colombo B, Paiva Maia YC, Piana de Andrade V, Teixeira Soares Mota S, Gonçalves de Araújo T, Van Petten de Vasconcelos Azevedo F, Soares FA, Oliani SM, Goulart LR
Biochimica et biophysica acta. Molecular cell research1865(9)1368-1382(2018 09)

FPR1 gene silencing suppresses cardiomyocyte apoptosis and ventricular remodeling in rats with ischemia/reperfusion injury through the inhibition of MAPK signaling pathway.
Zhou QL, Teng F, Zhang YS, Sun Q, Cao YX, Meng GW
Experimental cell research370(2)506-518(2018 09)

Intracellular formyl peptide receptor regulates naïve CD4 T cell migration.
Lee HY, Jeong YS, Lee M, Kweon HS, Huh YH, Park JS, Hwang JE, Kim K, Bae YS
Biochemical and biophysical research communications497(1)226-232(2018 02)

Expression and Functions of Formyl Peptide Receptor 1 in Drug-Resistant Bladder Cancer.
Jiang X, Lei T, Zhang M
Technology in cancer research & treatment171533034618769413(2018 01)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following FPR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FPR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10847	NM_001193306.2 Latest version!	Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
OHu10847	NM_002029.3 Latest version!	Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
View Old Accession Versions >>
OHu10847	NM_001193306.1	Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FPR1 ( NM_001193306.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180235.1 Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10847
Clone ID Related Accession (Same CDS sequence)	NM_001193306.1 , NM_001193306.2 , NM_002029.3
Accession Version	NM_001193306.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1549641600000
Organism	Homo sapiens(human)
Product	fMet-Leu-Phe receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018755.3. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DT217150.1, DB488002.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAGACAA ATTCCTCTCT CCCCACGAAC ATCTCTGGAG GGACACCTGC TGTATCTGCT 
GGCTATCTCT TCCTGGATAT CATCACTTAT CTGGTATTTG CAGTCACCTT TGTCCTCGGG 
GTCCTGGGCA ACGGGCTTGT GATCTGGGTG GCTGGATTCC GGATGACACA CACAGTCACC 
ACCATCAGTT ACCTGAACCT GGCCGTGGCT GACTTCTGTT TCACCTCCAC TTTGCCATTC 
TTCATGGTCA GGAAGGCCAT GGGAGGACAT TGGCCTTTCG GCTGGTTCCT GTGCAAATTC 
GTCTTTACCA TAGTGGACAT CAACTTGTTC GGAAGTGTCT TCCTGATCGC CCTCATTGCT 
CTGGACCGCT GTGTTTGCGT CCTGCATCCA GTCTGGACCC AGAACCACCG CACCGTGAGC 
CTGGCCAAGA AGGTGATCAT TGGGCCCTGG GTGATGGCTC TGCTCCTCAC ATTGCCAGTT 
ATCATTCGTG TGACTACAGT ACCTGGTAAA ACGGGGACAG TAGCCTGCAC TTTTAACTTT 
TCGCCCTGGA CCAACGACCC TAAAGAGAGG ATAAATGTGG CCGTTGCCAT GTTGACGGTG 
AGAGGCATCA TCCGGTTCAT CATTGGCTTC AGCGCACCCA TGTCCATCGT TGCTGTCAGT 
TATGGGCTTA TTGCCACCAA GATCCACAAG CAAGGCTTGA TTAAGTCCAG TCGTCCCTTA 
CGGGTCCTCT CCTTTGTCGC AGCAGCCTTT TTTCTCTGCT GGTCCCCATA TCAGGTGGTG 
GCCCTTATAG CCACAGTCAG AATCCGTGAG TTATTGCAAG GCATGTACAA AGAAATTGGT 
ATTGCAGTGG ATGTGACAAG TGCCCTGGCC TTCTTCAACA GCTGCCTCAA CCCCATGCTC 
TATGTCTTCA TGGGCCAGGA CTTCCGGGAG AGGCTGATCC ACGCCCTTCC CGCCAGTCTG 
GAGAGGGCCC TGACCGAGGA CTCAACCCAA ACCAGTGACA CAGCTACCAA TTCTACTTTA 
CCTTCTGCAG AGGTGGAGTT ACAGGCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180235.1
CDS	147..1199
Translation	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK

Target ORF information:

RefSeq Version	NM_001193306.1
Organism	Homo sapiens(human)
Definition	Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193306.1

ORF Insert Sequence:

ATGGAGACAA ATTCCTCTCT CCCCACGAAC ATCTCTGGAG GGACACCTGC TGTATCTGCT 
GGCTATCTCT TCCTGGATAT CATCACTTAT CTGGTATTTG CAGTCACCTT TGTCCTCGGG 
GTCCTGGGCA ACGGGCTTGT GATCTGGGTG GCTGGATTCC GGATGACACA CACAGTCACC 
ACCATCAGTT ACCTGAACCT GGCCGTGGCT GACTTCTGTT TCACCTCCAC TTTGCCATTC 
TTCATGGTCA GGAAGGCCAT GGGAGGACAT TGGCCTTTCG GCTGGTTCCT GTGCAAATTC 
GTCTTTACCA TAGTGGACAT CAACTTGTTC GGAAGTGTCT TCCTGATCGC CCTCATTGCT 
CTGGACCGCT GTGTTTGCGT CCTGCATCCA GTCTGGACCC AGAACCACCG CACCGTGAGC 
CTGGCCAAGA AGGTGATCAT TGGGCCCTGG GTGATGGCTC TGCTCCTCAC ATTGCCAGTT 
ATCATTCGTG TGACTACAGT ACCTGGTAAA ACGGGGACAG TAGCCTGCAC TTTTAACTTT 
TCGCCCTGGA CCAACGACCC TAAAGAGAGG ATAAATGTGG CCGTTGCCAT GTTGACGGTG 
AGAGGCATCA TCCGGTTCAT CATTGGCTTC AGCGCACCCA TGTCCATCGT TGCTGTCAGT 
TATGGGCTTA TTGCCACCAA GATCCACAAG CAAGGCTTGA TTAAGTCCAG TCGTCCCTTA 
CGGGTCCTCT CCTTTGTCGC AGCAGCCTTT TTTCTCTGCT GGTCCCCATA TCAGGTGGTG 
GCCCTTATAG CCACAGTCAG AATCCGTGAG TTATTGCAAG GCATGTACAA AGAAATTGGT 
ATTGCAGTGG ATGTGACAAG TGCCCTGGCC TTCTTCAACA GCTGCCTCAA CCCCATGCTC 
TATGTCTTCA TGGGCCAGGA CTTCCGGGAG AGGCTGATCC ACGCCCTTCC CGCCAGTCTG 
GAGAGGGCCC TGACCGAGGA CTCAACCCAA ACCAGTGACA CAGCTACCAA TTCTACTTTA 
CCTTCTGCAG AGGTGGAGTT ACAGGCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FPR1 ( NM_001193306.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180235.1 Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10847
Clone ID Related Accession (Same CDS sequence)	NM_001193306.1 , NM_001193306.2 , NM_002029.3
Accession Version	NM_001193306.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574006400000
Organism	Homo sapiens(human)
Product	fMet-Leu-Phe receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018755.3. On Jun 2, 2019 this sequence version replaced NM_001193306.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138517.1036365.1, SRR5189664.167613.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAGACAA ATTCCTCTCT CCCCACGAAC ATCTCTGGAG GGACACCTGC TGTATCTGCT 
GGCTATCTCT TCCTGGATAT CATCACTTAT CTGGTATTTG CAGTCACCTT TGTCCTCGGG 
GTCCTGGGCA ACGGGCTTGT GATCTGGGTG GCTGGATTCC GGATGACACA CACAGTCACC 
ACCATCAGTT ACCTGAACCT GGCCGTGGCT GACTTCTGTT TCACCTCCAC TTTGCCATTC 
TTCATGGTCA GGAAGGCCAT GGGAGGACAT TGGCCTTTCG GCTGGTTCCT GTGCAAATTC 
GTCTTTACCA TAGTGGACAT CAACTTGTTC GGAAGTGTCT TCCTGATCGC CCTCATTGCT 
CTGGACCGCT GTGTTTGCGT CCTGCATCCA GTCTGGACCC AGAACCACCG CACCGTGAGC 
CTGGCCAAGA AGGTGATCAT TGGGCCCTGG GTGATGGCTC TGCTCCTCAC ATTGCCAGTT 
ATCATTCGTG TGACTACAGT ACCTGGTAAA ACGGGGACAG TAGCCTGCAC TTTTAACTTT 
TCGCCCTGGA CCAACGACCC TAAAGAGAGG ATAAATGTGG CCGTTGCCAT GTTGACGGTG 
AGAGGCATCA TCCGGTTCAT CATTGGCTTC AGCGCACCCA TGTCCATCGT TGCTGTCAGT 
TATGGGCTTA TTGCCACCAA GATCCACAAG CAAGGCTTGA TTAAGTCCAG TCGTCCCTTA 
CGGGTCCTCT CCTTTGTCGC AGCAGCCTTT TTTCTCTGCT GGTCCCCATA TCAGGTGGTG 
GCCCTTATAG CCACAGTCAG AATCCGTGAG TTATTGCAAG GCATGTACAA AGAAATTGGT 
ATTGCAGTGG ATGTGACAAG TGCCCTGGCC TTCTTCAACA GCTGCCTCAA CCCCATGCTC 
TATGTCTTCA TGGGCCAGGA CTTCCGGGAG AGGCTGATCC ACGCCCTTCC CGCCAGTCTG 
GAGAGGGCCC TGACCGAGGA CTCAACCCAA ACCAGTGACA CAGCTACCAA TTCTACTTTA 
CCTTCTGCAG AGGTGGAGTT ACAGGCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180235.1
CDS	128..1180
Translation	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK

Target ORF information:

RefSeq Version	NM_001193306.2
Organism	Homo sapiens(human)
Definition	Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193306.2

ORF Insert Sequence:

ATGGAGACAA ATTCCTCTCT CCCCACGAAC ATCTCTGGAG GGACACCTGC TGTATCTGCT 
GGCTATCTCT TCCTGGATAT CATCACTTAT CTGGTATTTG CAGTCACCTT TGTCCTCGGG 
GTCCTGGGCA ACGGGCTTGT GATCTGGGTG GCTGGATTCC GGATGACACA CACAGTCACC 
ACCATCAGTT ACCTGAACCT GGCCGTGGCT GACTTCTGTT TCACCTCCAC TTTGCCATTC 
TTCATGGTCA GGAAGGCCAT GGGAGGACAT TGGCCTTTCG GCTGGTTCCT GTGCAAATTC 
GTCTTTACCA TAGTGGACAT CAACTTGTTC GGAAGTGTCT TCCTGATCGC CCTCATTGCT 
CTGGACCGCT GTGTTTGCGT CCTGCATCCA GTCTGGACCC AGAACCACCG CACCGTGAGC 
CTGGCCAAGA AGGTGATCAT TGGGCCCTGG GTGATGGCTC TGCTCCTCAC ATTGCCAGTT 
ATCATTCGTG TGACTACAGT ACCTGGTAAA ACGGGGACAG TAGCCTGCAC TTTTAACTTT 
TCGCCCTGGA CCAACGACCC TAAAGAGAGG ATAAATGTGG CCGTTGCCAT GTTGACGGTG 
AGAGGCATCA TCCGGTTCAT CATTGGCTTC AGCGCACCCA TGTCCATCGT TGCTGTCAGT 
TATGGGCTTA TTGCCACCAA GATCCACAAG CAAGGCTTGA TTAAGTCCAG TCGTCCCTTA 
CGGGTCCTCT CCTTTGTCGC AGCAGCCTTT TTTCTCTGCT GGTCCCCATA TCAGGTGGTG 
GCCCTTATAG CCACAGTCAG AATCCGTGAG TTATTGCAAG GCATGTACAA AGAAATTGGT 
ATTGCAGTGG ATGTGACAAG TGCCCTGGCC TTCTTCAACA GCTGCCTCAA CCCCATGCTC 
TATGTCTTCA TGGGCCAGGA CTTCCGGGAG AGGCTGATCC ACGCCCTTCC CGCCAGTCTG 
GAGAGGGCCC TGACCGAGGA CTCAACCCAA ACCAGTGACA CAGCTACCAA TTCTACTTTA 
CCTTCTGCAG AGGTGGAGTT ACAGGCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FPR1 ( NM_002029.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002020.1 Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10847
Clone ID Related Accession (Same CDS sequence)	NM_001193306.1 , NM_001193306.2 , NM_002029.3
Accession Version	NM_002029.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Homo sapiens(human)
Product	fMet-Leu-Phe receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB993626.1, BC005315.1, M60627.1 and BQ016000.1. This sequence is a reference standard in the RefSeqGene project. On Sep 29, 2003 this sequence version replaced NM_002029.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC005315.1, M60627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGAGACAA ATTCCTCTCT CCCCACGAAC ATCTCTGGAG GGACACCTGC TGTATCTGCT 
GGCTATCTCT TCCTGGATAT CATCACTTAT CTGGTATTTG CAGTCACCTT TGTCCTCGGG 
GTCCTGGGCA ACGGGCTTGT GATCTGGGTG GCTGGATTCC GGATGACACA CACAGTCACC 
ACCATCAGTT ACCTGAACCT GGCCGTGGCT GACTTCTGTT TCACCTCCAC TTTGCCATTC 
TTCATGGTCA GGAAGGCCAT GGGAGGACAT TGGCCTTTCG GCTGGTTCCT GTGCAAATTC 
GTCTTTACCA TAGTGGACAT CAACTTGTTC GGAAGTGTCT TCCTGATCGC CCTCATTGCT 
CTGGACCGCT GTGTTTGCGT CCTGCATCCA GTCTGGACCC AGAACCACCG CACCGTGAGC 
CTGGCCAAGA AGGTGATCAT TGGGCCCTGG GTGATGGCTC TGCTCCTCAC ATTGCCAGTT 
ATCATTCGTG TGACTACAGT ACCTGGTAAA ACGGGGACAG TAGCCTGCAC TTTTAACTTT 
TCGCCCTGGA CCAACGACCC TAAAGAGAGG ATAAATGTGG CCGTTGCCAT GTTGACGGTG 
AGAGGCATCA TCCGGTTCAT CATTGGCTTC AGCGCACCCA TGTCCATCGT TGCTGTCAGT 
TATGGGCTTA TTGCCACCAA GATCCACAAG CAAGGCTTGA TTAAGTCCAG TCGTCCCTTA 
CGGGTCCTCT CCTTTGTCGC AGCAGCCTTT TTTCTCTGCT GGTCCCCATA TCAGGTGGTG 
GCCCTTATAG CCACAGTCAG AATCCGTGAG TTATTGCAAG GCATGTACAA AGAAATTGGT 
ATTGCAGTGG ATGTGACAAG TGCCCTGGCC TTCTTCAACA GCTGCCTCAA CCCCATGCTC 
TATGTCTTCA TGGGCCAGGA CTTCCGGGAG AGGCTGATCC ACGCCCTTCC CGCCAGTCTG 
GAGAGGGCCC TGACCGAGGA CTCAACCCAA ACCAGTGACA CAGCTACCAA TTCTACTTTA 
CCTTCTGCAG AGGTGGAGTT ACAGGCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002020.1
CDS	96..1148
Translation	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK

Target ORF information:

RefSeq Version	NM_002029.3
Organism	Homo sapiens(human)
Definition	Homo sapiens formyl peptide receptor 1 (FPR1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002029.3

ORF Insert Sequence:

ATGGAGACAA ATTCCTCTCT CCCCACGAAC ATCTCTGGAG GGACACCTGC TGTATCTGCT 
GGCTATCTCT TCCTGGATAT CATCACTTAT CTGGTATTTG CAGTCACCTT TGTCCTCGGG 
GTCCTGGGCA ACGGGCTTGT GATCTGGGTG GCTGGATTCC GGATGACACA CACAGTCACC 
ACCATCAGTT ACCTGAACCT GGCCGTGGCT GACTTCTGTT TCACCTCCAC TTTGCCATTC 
TTCATGGTCA GGAAGGCCAT GGGAGGACAT TGGCCTTTCG GCTGGTTCCT GTGCAAATTC 
GTCTTTACCA TAGTGGACAT CAACTTGTTC GGAAGTGTCT TCCTGATCGC CCTCATTGCT 
CTGGACCGCT GTGTTTGCGT CCTGCATCCA GTCTGGACCC AGAACCACCG CACCGTGAGC 
CTGGCCAAGA AGGTGATCAT TGGGCCCTGG GTGATGGCTC TGCTCCTCAC ATTGCCAGTT 
ATCATTCGTG TGACTACAGT ACCTGGTAAA ACGGGGACAG TAGCCTGCAC TTTTAACTTT 
TCGCCCTGGA CCAACGACCC TAAAGAGAGG ATAAATGTGG CCGTTGCCAT GTTGACGGTG 
AGAGGCATCA TCCGGTTCAT CATTGGCTTC AGCGCACCCA TGTCCATCGT TGCTGTCAGT 
TATGGGCTTA TTGCCACCAA GATCCACAAG CAAGGCTTGA TTAAGTCCAG TCGTCCCTTA 
CGGGTCCTCT CCTTTGTCGC AGCAGCCTTT TTTCTCTGCT GGTCCCCATA TCAGGTGGTG 
GCCCTTATAG CCACAGTCAG AATCCGTGAG TTATTGCAAG GCATGTACAA AGAAATTGGT 
ATTGCAGTGG ATGTGACAAG TGCCCTGGCC TTCTTCAACA GCTGCCTCAA CCCCATGCTC 
TATGTCTTCA TGGGCCAGGA CTTCCGGGAG AGGCTGATCC ACGCCCTTCC CGCCAGTCTG 
GAGAGGGCCC TGACCGAGGA CTCAACCCAA ACCAGTGACA CAGCTACCAA TTCTACTTTA 
CCTTCTGCAG AGGTGGAGTT ACAGGCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

FPR1 is the plague receptor on host immune cells.
Nature574(7776)57-62(2019 10)
Osei-Owusu P,Charlton TM,Kim HK,Missiakas D,Schneewind O

Inhibition of the AnxA1/FPR1 autocrine axis reduces MDA-MB-231 breast cancer cell growth and aggressiveness in vitro and in vivo.
Biochimica et biophysica acta. Molecular cell research1865(9)1368-1382(2018 09)
Vecchi L,Alves Pereira Zóia M,Goss Santos T,de Oliveira Beserra A,Colaço Ramos CM,França Matias Colombo B,Paiva Maia YC,Piana de Andrade V,Teixeira Soares Mota S,Gonçalves de Araújo T,Van Petten de Vasconcelos Azevedo F,Soares FA,Oliani SM,Goulart LR

FPR1 gene silencing suppresses cardiomyocyte apoptosis and ventricular remodeling in rats with ischemia/reperfusion injury through the inhibition of MAPK signaling pathway.
Experimental cell research370(2)506-518(2018 09)
Zhou QL,Teng F,Zhang YS,Sun Q,Cao YX,Meng GW

Intracellular formyl peptide receptor regulates naïve CD4 T cell migration.
Biochemical and biophysical research communications497(1)226-232(2018 02)
Lee HY,Jeong YS,Lee M,Kweon HS,Huh YH,Park JS,Hwang JE,Kim K,Bae YS

Expression and Functions of Formyl Peptide Receptor 1 in Drug-Resistant Bladder Cancer.
Technology in cancer research & treatment171533034618769413(2018 01)
Jiang X,Lei T,Zhang M

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FPR1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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