GIMAP6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GIMAP6
Entrez Gene ID	474344
Full Name	GTPase, IMAP family member 6
Synonyms	IAN-2,IAN-6,IAN2,IAN6
General protein information	Preferred Names GTPase, IMAP family member 6 Names GTPase IMAP family member 6 immune associated nucleotide 2 immune associated nucleotide 6 immune-associated nucleotide-binding protein 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q36.1
Summary	This gene encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7. [provided by RefSeq, Sep 2011].
Disorder MIM:	616960

mRNA and Protein(s)

mRNA	Protein	Name
NM_024711.6	NP_078987.3	GTPase IMAP family member 6 isoform 1
NM_024711.5	NP_078987.3	GTPase IMAP family member 6 isoform 1
NM_001244071.1	NP_001231000.1	GTPase IMAP family member 6 isoform 3
NM_001244071.2	NP_001231000.1	GTPase IMAP family member 6 isoform 3
NM_001244072.1	NP_001231001.1	GTPase IMAP family member 6 isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	GIMAP6	NP_078987.3
Bos taurus (cattle)	GIMAP6	XP_005206001.1
Rattus norvegicus (Norway rat)	Gimap6	NP_001011968.1
Pan troglodytes (chimpanzee)	GIMAP6	XP_003318947.1
Mus musculus (house mouse)	Gimap6	NP_694815.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional and biochemical characterization of a T cell-associated anti-apoptotic protein, GIMAP6.
Ho CH, Tsai SF
The Journal of biological chemistry292(22)9305-9319(2017 06)

Dysregulation of GTPase IMAP family members in hepatocellular cancer.
Huang Z, Zhang W, Gao C, Ji B, Chi X, Zheng W, Wang HL
Molecular medicine reports14(5)4119-4123(2016 Nov)

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel D, Arasu BS, Marino SF, Lamprecht B, Köchert K, Rosenbaum E, Eichhorst J, Wiesner B, Behlke J, Rocks O, Mathas S, Daumke O
Structure (London, England : 1993)21(4)550-9(2013 Apr)

Dysregulation of GIMAP genes in non-small cell lung cancer.
Shiao YM, Chang YH, Liu YM, Li JC, Su JS, Liu KJ, Liu YF, Lin MW, Tsai SF
Lung cancer (Amsterdam, Netherlands)62(3)287-94(2008 Dec)

Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.
Krücken J, Schroetel RM, Müller IU, Saïdani N, Marinovski P, Benten WP, Stamm O, Wunderlich F
Gene341291-304(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GIMAP6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GIMAP6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15453	NM_024711.6 Latest version!	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu15466	NM_001244072.1 Latest version!	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu15494	NM_001244071.2 Latest version!	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu15453	NM_024711.5	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu15494	NM_001244071.1	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GIMAP6 ( NM_024711.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_078987.3 Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15453
Clone ID Related Accession (Same CDS sequence)	NM_024711.6 , NM_024711.5
Accession Version	NM_024711.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565020800000
Organism	Homo sapiens(human)
Product	GTPase IMAP family member 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CR749355.1 and BC060760.1. On Nov 23, 2018 this sequence version replaced NM_024711.5. Transcript Variant: This variant (1) encodes isoform 1. ##Evidence-Data-START## Transcript exon combination :: CR749355.1, SRR1660805.244915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2150385 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000328902.9/ ENSP00000330374.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTA AGGGAGAAAG AACAGAAGAC CCCAAGGAGA 
CTGAGGCTCA TTCTCATGGG GAAAACAGGG AGTGGGAAGA GTGCAACAGG AAACAGCATC 
CTCGGCAGGG ACGTCTTCGA GTCTAAACTC AGCACCAGAC CCGTGACCAA GACCTCCCAG 
AGACGGAGCC GAGAGTGGGC TGGGAAGGAG CTTGAGGTGA TTGACACACC CAACATTCTG 
TCCCCCCAGG TCTCGCCAGA GGTGGCAGAC GCTATCTGCC AAGCCATCGT CTTATCCGCC 
CCAGGGCCCC ACGCCGTGCT CCTGGTGACA CAACTGGGCC GGTTCACGGA TGAGGATCAG 
CAGGTGGTCA GGCGCCTGCA GGAGGTCTTT GGAGTGGGGG TTCTGGGTCA CACCATCCTG 
GTGTTCACCC GGAAGGAAGA CCTGGCTGGC GGCTCCCTGG AAGACTATGT GCGAGAGACC 
AACAACCAGG CCCTTGCCTG GCTGGATGTG ACCCTTGCAC GGCGCCATTG CGGCTTCAAC 
AACAGGGCAC AGGGGGAGGA GCAGGAGGCC CAACTGCGAG AGCTCATGGA GAAAGTTGAA 
GCCATTATGT GGGAAAACGA AGGAGATTAT TACAGCAACA AGGCTTACCA ATATACCCAG 
CAAAACTTTC GGCTGAAAGA ACTACAGGAA AGGCAAGTAA GCCAGGGCCA AGGCTCTGAG 
GACGTGCCTG GTGAGGAGTC TTGGCTGGAA GGACTGTCCC AGATCCAGAA GGAATCTGAG 
GAAGCCCACA GATGCCTGCT GGGGAAGGCT GACCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078987.3
CDS	218..1096
Translation	MEEEEYEQIPQENPPEELSQDPVLELSGGLREKEQKTPRRLRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKELEVIDTPNILSPQVSPEVADAICQAIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRLQEVFGVGVLGHTILVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQGEEQEAQLRELMEKVEAIMWENEGDYYSNKAYQYTQQNFRLKELQERQVSQGQGSEDVPGEESWLEGLSQIQKESEEAHRCLLGKADL

Target ORF information:

RefSeq Version	NM_024711.6
Organism	Homo sapiens(human)
Definition	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024711.6

ORF Insert Sequence:

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTA AGGGAGAAAG AACAGAAGAC CCCAAGGAGA 
CTGAGGCTCA TTCTCATGGG GAAAACAGGG AGTGGGAAGA GTGCAACAGG AAACAGCATC 
CTCGGCAGGG ACGTCTTCGA GTCTAAACTC AGCACCAGAC CCGTGACCAA GACCTCCCAG 
AGACGGAGCC GAGAGTGGGC TGGGAAGGAG CTTGAGGTGA TTGACACACC CAACATTCTG 
TCCCCCCAGG TCTCGCCAGA GGTGGCAGAC GCTATCTGCC AAGCCATCGT CTTATCCGCC 
CCAGGGCCCC ACGCCGTGCT CCTGGTGACA CAACTGGGCC GGTTCACGGA TGAGGATCAG 
CAGGTGGTCA GGCGCCTGCA GGAGGTCTTT GGAGTGGGGG TTCTGGGTCA CACCATCCTG 
GTGTTCACCC GGAAGGAAGA CCTGGCTGGC GGCTCCCTGG AAGACTATGT GCGAGAGACC 
AACAACCAGG CCCTTGCCTG GCTGGATGTG ACCCTTGCAC GGCGCCATTG CGGCTTCAAC 
AACAGGGCAC AGGGGGAGGA GCAGGAGGCC CAACTGCGAG AGCTCATGGA GAAAGTTGAA 
GCCATTATGT GGGAAAACGA AGGAGATTAT TACAGCAACA AGGCTTACCA ATATACCCAG 
CAAAACTTTC GGCTGAAAGA ACTACAGGAA AGGCAAGTAA GCCAGGGCCA AGGCTCTGAG 
GACGTGCCTG GTGAGGAGTC TTGGCTGGAA GGACTGTCCC AGATCCAGAA GGAATCTGAG 
GAAGCCCACA GATGCCTGCT GGGGAAGGCT GACCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GIMAP6 ( NM_024711.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_078987.3 Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15453
Clone ID Related Accession (Same CDS sequence)	NM_024711.6 , NM_024711.5
Accession Version	NM_024711.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	GTPase IMAP family member 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC384795.1, CR749355.1 and BC060760.1. On Sep 14, 2011 this sequence version replaced NM_024711.4. Transcript Variant: This variant (1) encodes isoform 1. ##Evidence-Data-START## Transcript exon combination :: CR749355.1, SRR1660805.244915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2150385 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTA AGGGAGAAAG AACAGAAGAC CCCAAGGAGA 
CTGAGGCTCA TTCTCATGGG GAAAACAGGG AGTGGGAAGA GTGCAACAGG AAACAGCATC 
CTCGGCAGGG ACGTCTTCGA GTCTAAACTC AGCACCAGAC CCGTGACCAA GACCTCCCAG 
AGACGGAGCC GAGAGTGGGC TGGGAAGGAG CTTGAGGTGA TTGACACACC CAACATTCTG 
TCCCCCCAGG TCTCGCCAGA GGTGGCAGAC GCTATCTGCC AAGCCATCGT CTTATCCGCC 
CCAGGGCCCC ACGCCGTGCT CCTGGTGACA CAACTGGGCC GGTTCACGGA TGAGGATCAG 
CAGGTGGTCA GGCGCCTGCA GGAGGTCTTT GGAGTGGGGG TTCTGGGTCA CACCATCCTG 
GTGTTCACCC GGAAGGAAGA CCTGGCTGGC GGCTCCCTGG AAGACTATGT GCGAGAGACC 
AACAACCAGG CCCTTGCCTG GCTGGATGTG ACCCTTGCAC GGCGCCATTG CGGCTTCAAC 
AACAGGGCAC AGGGGGAGGA GCAGGAGGCC CAACTGCGAG AGCTCATGGA GAAAGTTGAA 
GCCATTATGT GGGAAAACGA AGGAGATTAT TACAGCAACA AGGCTTACCA ATATACCCAG 
CAAAACTTTC GGCTGAAAGA ACTACAGGAA AGGCAAGTAA GCCAGGGCCA AGGCTCTGAG 
GACGTGCCTG GTGAGGAGTC TTGGCTGGAA GGACTGTCCC AGATCCAGAA GGAATCTGAG 
GAAGCCCACA GATGCCTGCT GGGGAAGGCT GACCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078987.3
CDS	481..1359
Translation	MEEEEYEQIPQENPPEELSQDPVLELSGGLREKEQKTPRRLRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKELEVIDTPNILSPQVSPEVADAICQAIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRLQEVFGVGVLGHTILVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQGEEQEAQLRELMEKVEAIMWENEGDYYSNKAYQYTQQNFRLKELQERQVSQGQGSEDVPGEESWLEGLSQIQKESEEAHRCLLGKADL

Target ORF information:

RefSeq Version	NM_024711.5
Organism	Homo sapiens(human)
Definition	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024711.5

ORF Insert Sequence:

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTA AGGGAGAAAG AACAGAAGAC CCCAAGGAGA 
CTGAGGCTCA TTCTCATGGG GAAAACAGGG AGTGGGAAGA GTGCAACAGG AAACAGCATC 
CTCGGCAGGG ACGTCTTCGA GTCTAAACTC AGCACCAGAC CCGTGACCAA GACCTCCCAG 
AGACGGAGCC GAGAGTGGGC TGGGAAGGAG CTTGAGGTGA TTGACACACC CAACATTCTG 
TCCCCCCAGG TCTCGCCAGA GGTGGCAGAC GCTATCTGCC AAGCCATCGT CTTATCCGCC 
CCAGGGCCCC ACGCCGTGCT CCTGGTGACA CAACTGGGCC GGTTCACGGA TGAGGATCAG 
CAGGTGGTCA GGCGCCTGCA GGAGGTCTTT GGAGTGGGGG TTCTGGGTCA CACCATCCTG 
GTGTTCACCC GGAAGGAAGA CCTGGCTGGC GGCTCCCTGG AAGACTATGT GCGAGAGACC 
AACAACCAGG CCCTTGCCTG GCTGGATGTG ACCCTTGCAC GGCGCCATTG CGGCTTCAAC 
AACAGGGCAC AGGGGGAGGA GCAGGAGGCC CAACTGCGAG AGCTCATGGA GAAAGTTGAA 
GCCATTATGT GGGAAAACGA AGGAGATTAT TACAGCAACA AGGCTTACCA ATATACCCAG 
CAAAACTTTC GGCTGAAAGA ACTACAGGAA AGGCAAGTAA GCCAGGGCCA AGGCTCTGAG 
GACGTGCCTG GTGAGGAGTC TTGGCTGGAA GGACTGTCCC AGATCCAGAA GGAATCTGAG 
GAAGCCCACA GATGCCTGCT GGGGAAGGCT GACCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GIMAP6 ( NM_001244072.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231001.1 Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15466
Clone ID Related Accession (Same CDS sequence)	NM_001244072.1
Accession Version	NM_001244072.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1564934400000
Organism	Homo sapiens(human)
Product	GTPase IMAP family member 6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC384795.1, AK294989.1 and BC060760.1. Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is longer than isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.138033.1, AK294989.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155770, SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGCTCT GCTCTTGCAC TGGGAGAGAA CGTTCAGCCC 
CACCTTCAAG GATGTGGGCC CAGAATGGTG GCCCAGCGCT GGTTTCAGGG CAGATGTTGG 
TCTTTTACAA TCTGCCCCTG CAGTCTGGGG GTACACCCAG AGGCTCCTGG TGATGACAAG 
ATGGGGTACA TGGGCCCTTA CCCCAGTTCC CTCTGCTTTC TTTGGATATT TCTAGGTCTA 
AGGGAGAAAG AACAGAAGAC CCCAAGGAGA CTGAGGCTCA TTCTCATGGG GAAAACAGGG 
AGTGGGAAGA GTGCAACAGG AAACAGCATC CTCGGCAGGG ACGTCTTCGA GTCTAAACTC 
AGCACCAGAC CCGTGACCAA GACCTCCCAG AGACGGAGCC GAGAGTGGGC TGGGAAGGAG 
CTTGAGGTGA TTGACACACC CAACATTCTG TCCCCCCAGG TCTCGCCAGA GGTGGCAGAC 
GCTATCTGCC AAGCCATCGT CTTATCCGCC CCAGGGCCCC ACGCCGTGCT CCTGGTGACA 
CAACTGGGCC GGTTCACGGA TGAGGATCAG CAGGTGGTCA GGCGCCTGCA GGAGGTCTTT 
GGAGTGGGGG TTCTGGGTCA CACCATCCTG GTGTTCACCC GGAAGGAAGA CCTGGCTGGC 
GGCTCCCTGG AAGACTATGT GCGAGAGACC AACAACCAGG CCCTTGCCTG GCTGGATGTG 
ACCCTTGCAC GGCGCCATTG CGGCTTCAAC AACAGGGCAC AGGGGGAGGA GCAGGAGGCC 
CAACTGCGAG AGCTCATGGA GAAAGTTGAA GCCATTATGT GGGAAAACGA AGGAGATTAT 
TACAGCAACA AGGCTTACCA ATATACCCAG CAAAACTTTC GGCTGAAAGA ACTACAGGAA 
AGGCAAGTAA GCCAGGGCCA AGGCTCTGAG GACGTGCCTG GTGAGGAGTC TTGGCTGGAA 
GGACTGTCCC AGATCCAGAA GGAATCTGAG GAAGCCCACA GATGCCTGCT GGGGAAGGCT 
GACCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231001.1
CDS	481..1569
Translation	MEEEEYEQIPQENPPEELSQDPVLELSGGSALALGENVQPHLQGCGPRMVAQRWFQGRCWSFTICPCSLGVHPEAPGDDKMGYMGPYPSSLCFLWIFLGLREKEQKTPRRLRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKELEVIDTPNILSPQVSPEVADAICQAIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRLQEVFGVGVLGHTILVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQGEEQEAQLRELMEKVEAIMWENEGDYYSNKAYQYTQQNFRLKELQERQVSQGQGSEDVPGEESWLEGLSQIQKESEEAHRCLLGKADL

Target ORF information:

RefSeq Version	NM_001244072.1
Organism	Homo sapiens(human)
Definition	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244072.1

ORF Insert Sequence:

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGCTCT GCTCTTGCAC TGGGAGAGAA CGTTCAGCCC 
CACCTTCAAG GATGTGGGCC CAGAATGGTG GCCCAGCGCT GGTTTCAGGG CAGATGTTGG 
TCTTTTACAA TCTGCCCCTG CAGTCTGGGG GTACACCCAG AGGCTCCTGG TGATGACAAG 
ATGGGGTACA TGGGCCCTTA CCCCAGTTCC CTCTGCTTTC TTTGGATATT TCTAGGTCTA 
AGGGAGAAAG AACAGAAGAC CCCAAGGAGA CTGAGGCTCA TTCTCATGGG GAAAACAGGG 
AGTGGGAAGA GTGCAACAGG AAACAGCATC CTCGGCAGGG ACGTCTTCGA GTCTAAACTC 
AGCACCAGAC CCGTGACCAA GACCTCCCAG AGACGGAGCC GAGAGTGGGC TGGGAAGGAG 
CTTGAGGTGA TTGACACACC CAACATTCTG TCCCCCCAGG TCTCGCCAGA GGTGGCAGAC 
GCTATCTGCC AAGCCATCGT CTTATCCGCC CCAGGGCCCC ACGCCGTGCT CCTGGTGACA 
CAACTGGGCC GGTTCACGGA TGAGGATCAG CAGGTGGTCA GGCGCCTGCA GGAGGTCTTT 
GGAGTGGGGG TTCTGGGTCA CACCATCCTG GTGTTCACCC GGAAGGAAGA CCTGGCTGGC 
GGCTCCCTGG AAGACTATGT GCGAGAGACC AACAACCAGG CCCTTGCCTG GCTGGATGTG 
ACCCTTGCAC GGCGCCATTG CGGCTTCAAC AACAGGGCAC AGGGGGAGGA GCAGGAGGCC 
CAACTGCGAG AGCTCATGGA GAAAGTTGAA GCCATTATGT GGGAAAACGA AGGAGATTAT 
TACAGCAACA AGGCTTACCA ATATACCCAG CAAAACTTTC GGCTGAAAGA ACTACAGGAA 
AGGCAAGTAA GCCAGGGCCA AGGCTCTGAG GACGTGCCTG GTGAGGAGTC TTGGCTGGAA 
GGACTGTCCC AGATCCAGAA GGAATCTGAG GAAGCCCACA GATGCCTGCT GGGGAAGGCT 
GACCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GIMAP6 ( NM_001244071.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231000.1 Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15494
Clone ID Related Accession (Same CDS sequence)	NM_001244071.1 , NM_001244071.2
Accession Version	NM_001244071.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 189bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1529769600000
Organism	Homo sapiens(human)
Product	GTPase IMAP family member 6 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC384795.1, DA582331.1 and BC060760.1. On Sep 13, 2011 this sequence version replaced NR_024115.1. Transcript Variant: This variant (3) uses an alternate splice site in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.213323.1, SRR1660807.189656.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2150385 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTC GCCAGAGGTG GCAGACGCTA TCTGCCAAGC 
CATCGTCTTA TCCGCCCCAG GGCCCCACGC CGTGCTCCTG GTGACACAAC TGGGCCGGTT 
CACGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231000.1
CDS	481..669
Translation	MEEEEYEQIPQENPPEELSQDPVLELSGGLARGGRRYLPSHRLIRPRAPRRAPGDTTGPVHG

Target ORF information:

RefSeq Version	NM_001244071.1
Organism	Homo sapiens(human)
Definition	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244071.1

ORF Insert Sequence:

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTC GCCAGAGGTG GCAGACGCTA TCTGCCAAGC 
CATCGTCTTA TCCGCCCCAG GGCCCCACGC CGTGCTCCTG GTGACACAAC TGGGCCGGTT 
CACGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GIMAP6 ( NM_001244071.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231000.1 Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 3, mRNA.

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CloneID	OHu15494
Clone ID Related Accession (Same CDS sequence)	NM_001244071.1 , NM_001244071.2
Accession Version	NM_001244071.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 189bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Homo sapiens(human)
Product	GTPase IMAP family member 6 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA582331.1 and BC060760.1. On Jun 1, 2019 this sequence version replaced NM_001244071.1. Transcript Variant: This variant (3) uses an alternate splice site in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.213323.1, SRR1660807.189656.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2150385 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTC GCCAGAGGTG GCAGACGCTA TCTGCCAAGC 
CATCGTCTTA TCCGCCCCAG GGCCCCACGC CGTGCTCCTG GTGACACAAC TGGGCCGGTT 
CACGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231000.1
CDS	218..406
Translation	MEEEEYEQIPQENPPEELSQDPVLELSGGLARGGRRYLPSHRLIRPRAPRRAPGDTTGPVHG

Target ORF information:

RefSeq Version	NM_001244071.2
Organism	Homo sapiens(human)
Definition	Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244071.2

ORF Insert Sequence:

ATGGAGGAAG AAGAATATGA ACAAATTCCC CAGGAGAATC CCCCAGAAGA GCTGTCCCAG 
GATCCTGTGC TGGAGCTGTC AGGAGGTCTC GCCAGAGGTG GCAGACGCTA TCTGCCAAGC 
CATCGTCTTA TCCGCCCCAG GGCCCCACGC CGTGCTCCTG GTGACACAAC TGGGCCGGTT 
CACGGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional and biochemical characterization of a T cell-associated anti-apoptotic protein, GIMAP6.
The Journal of biological chemistry292(22)9305-9319(2017 06)
Ho CH,Tsai SF

Dysregulation of GTPase IMAP family members in hepatocellular cancer.
Molecular medicine reports14(5)4119-4123(2016 Nov)
Huang Z,Zhang W,Gao C,Ji B,Chi X,Zheng W,Wang HL

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Structure (London, England : 1993)21(4)550-9(2013 Apr)
Schwefel D,Arasu BS,Marino SF,Lamprecht B,Köchert K,Rosenbaum E,Eichhorst J,Wiesner B,Behlke J,Rocks O,Mathas S,Daumke O

Dysregulation of GIMAP genes in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands)62(3)287-94(2008 Dec)
Shiao YM,Chang YH,Liu YM,Li JC,Su JS,Liu KJ,Liu YF,Lin MW,Tsai SF

Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.
Gene341291-304(2004 Oct)
Krücken J,Schroetel RM,Müller IU,Saïdani N,Marinovski P,Benten WP,Stamm O,Wunderlich F

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GIMAP6 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

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