Gimap6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gimap6
Entrez Gene ID	231931
Full Name	GTPase, IMAP family member 6
Synonyms	4833419H03Rik,Ian6,mFLJ00102
General protein information	Preferred Names GTPase, IMAP family member 6 Names GTPase IMAP family member 6 IAN-6 immune associated nucleotide 6 immunity-associated nucleotide 6 protein mIAN6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 B2.3
Summary	This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_153175.3	NP_694815.1	GTPase IMAP family member 6

Pathways from BioSystems

Homologies

Homo sapiens (human)	GIMAP6	NP_078987.3
Bos taurus (cattle)	GIMAP6	XP_005206001.1
Rattus norvegicus (Norway rat)	Gimap6	NP_001011968.1
Pan troglodytes (chimpanzee)	GIMAP6	XP_003318947.1
Mus musculus (house mouse)	Gimap6	NP_694815.1

Gene Ontology
Bibliography

Related articles in PubMed

GIMAP6 is required for T cell maintenance and efficient autophagy in mice.
Pascall JC, Webb LMC, Eskelinen EL, Innocentin S, Attaf-Bouabdallah N, Butcher GW
PloS one13(5)e0196504(2018)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification.
Zhou P, Zhang Y, Ma Q, Gu F, Day DS, He A, Zhou B, Li J, Stevens SM, Romo D, Pu WT
Proceedings of the National Academy of Sciences of the United States of America110(38)15395-400(2013 Sep)

Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.
Krücken J, Schroetel RM, Müller IU, Saïdani N, Marinovski P, Benten WP, Stamm O, Wunderlich F
Gene341291-304(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gimap6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gimap6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18033	NM_153175.3 Latest version!	Mus musculus GTPase, IMAP family member 6 (Gimap6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gimap6 ( NM_153175.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_694815.1 Mus musculus GTPase, IMAP family member 6 (Gimap6), mRNA.

Price & Availability↑

CloneID	OMu18033
Clone ID Related Accession (Same CDS sequence)	NM_153175.3
Accession Version	NM_153175.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571328000000
Organism	Mus musculus(house mouse)
Product	GTPase IMAP family member 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU699766.1, BC028779.1 and AK050328.1. On Jan 15, 2005 this sequence version replaced NM_153175.2. ##Evidence-Data-START## Transcript exon combination :: AK050328.1, BC028779.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATTGGC TTTACAGAAA AACACTCGGG TCCATCGGCT CATGTTCTAT AGAAACTTTT 
CCCTGGCCAT TCTATTCATT CTTTCAGAGA ATCTACATTT CGACCCCACC AGGAAAGCCA 
GAAAATTCAC CAGAGACCAG TGCTACTGAA GTCGGGGAAC AGAGACCTTC TTGCCTGTCA 
GCCAGCCCAG TGGTGGAAGA GGAAGAGTGT GAGCACAGAC CTGAGAAGAA TCCCACAAGG 
CAGTGGCCCC TGGACTCTGG ACAAGGATTG ACAAAAGGTC TGAAGGAGAA AAAACTCACC 
CCAAAGAGAC TGCAGCTCCT TCTGGTGGGG AAAACAGGAA GCGGGAAAAG TGCAACAGGG 
AACAGCATCC TTGGCAGGCA AGCCTTTGAA TCCAAAATCA GCGCTCGACC AGTGACCACG 
ACATTCCAGA AAGGGACTAG AGAGTTTGAG GGGAAAGAAC TTGAGGTGAT CGACACCCCA 
GATATTTTTT CACCTCAGAA CCAGCCTGAG GCAACAGCTA AGAAGATCTG TGACCTCTTG 
GCCTCACCAG GGCCCCATGC AGTGCTGCTG GTGATACAGG TAGGCCGGTA CACTGCCGAG 
GACCAGGCGG TAGCCAGGTG CCTCCAGGAG ATCTTTGGAA ACACGATCCT GGCTTACACT 
ATTCTGGTGT TCACCCGGAA GGAAGACCTG GCTGAGGGCT CCTTAGAAGA ATATATTCAA 
GAGAACAACA ATAAGAGCCT GGATGTTCTG GATGTTGCAT GTGAGAGGCG CCACTGTGGC 
TTCAACAACA AGGCACAAGG GGATGAGCAG GAGGCCCAGT TGAAGAAACT TATGGAGGAA 
GTCGAATTGA TCTTGTGGGA AAATGAGGGC CATTGTTACA CCATGGAATT TCCAAATGTT 
CCCAGCAAGA CACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694815.1
CDS	95..1012
Translation	MDWLYRKTLGSIGSCSIETFPWPFYSFFQRIYISTPPGKPENSPETSATEVGEQRPSCLSASPVVEEEECEHRPEKNPTRQWPLDSGQGLTKGLKEKKLTPKRLQLLLVGKTGSGKSATGNSILGRQAFESKISARPVTTTFQKGTREFEGKELEVIDTPDIFSPQNQPEATAKKICDLLASPGPHAVLLVIQVGRYTAEDQAVARCLQEIFGNTILAYTILVFTRKEDLAEGSLEEYIQENNNKSLDVLDVACERRHCGFNNKAQGDEQEAQLKKLMEEVELILWENEGHCYTMEFPNVPSKTL

Target ORF information:

RefSeq Version	NM_153175.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus GTPase, IMAP family member 6 (Gimap6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153175.3

ORF Insert Sequence:

ATGGATTGGC TTTACAGAAA AACACTCGGG TCCATCGGCT CATGTTCTAT AGAAACTTTT 
CCCTGGCCAT TCTATTCATT CTTTCAGAGA ATCTACATTT CGACCCCACC AGGAAAGCCA 
GAAAATTCAC CAGAGACCAG TGCTACTGAA GTCGGGGAAC AGAGACCTTC TTGCCTGTCA 
GCCAGCCCAG TGGTGGAAGA GGAAGAGTGT GAGCACAGAC CTGAGAAGAA TCCCACAAGG 
CAGTGGCCCC TGGACTCTGG ACAAGGATTG ACAAAAGGTC TGAAGGAGAA AAAACTCACC 
CCAAAGAGAC TGCAGCTCCT TCTGGTGGGG AAAACAGGAA GCGGGAAAAG TGCAACAGGG 
AACAGCATCC TTGGCAGGCA AGCCTTTGAA TCCAAAATCA GCGCTCGACC AGTGACCACG 
ACATTCCAGA AAGGGACTAG AGAGTTTGAG GGGAAAGAAC TTGAGGTGAT CGACACCCCA 
GATATTTTTT CACCTCAGAA CCAGCCTGAG GCAACAGCTA AGAAGATCTG TGACCTCTTG 
GCCTCACCAG GGCCCCATGC AGTGCTGCTG GTGATACAGG TAGGCCGGTA CACTGCCGAG 
GACCAGGCGG TAGCCAGGTG CCTCCAGGAG ATCTTTGGAA ACACGATCCT GGCTTACACT 
ATTCTGGTGT TCACCCGGAA GGAAGACCTG GCTGAGGGCT CCTTAGAAGA ATATATTCAA 
GAGAACAACA ATAAGAGCCT GGATGTTCTG GATGTTGCAT GTGAGAGGCG CCACTGTGGC 
TTCAACAACA AGGCACAAGG GGATGAGCAG GAGGCCCAGT TGAAGAAACT TATGGAGGAA 
GTCGAATTGA TCTTGTGGGA AAATGAGGGC CATTGTTACA CCATGGAATT TCCAAATGTT 
CCCAGCAAGA CACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GIMAP6 is required for T cell maintenance and efficient autophagy in mice.
PloS one13(5)e0196504(2018)
Pascall JC,Webb LMC,Eskelinen EL,Innocentin S,Attaf-Bouabdallah N,Butcher GW

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bućan M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification.
Proceedings of the National Academy of Sciences of the United States of America110(38)15395-400(2013 Sep)
Zhou P,Zhang Y,Ma Q,Gu F,Day DS,He A,Zhou B,Li J,Stevens SM,Romo D,Pu WT

Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.
Gene341291-304(2004 Oct)
Krücken J,Schroetel RM,Müller IU,Saïdani N,Marinovski P,Benten WP,Stamm O,Wunderlich F

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Gimap6 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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