| Gene Symbol | TMED6 |
| Entrez Gene ID | 146456 |
| Full Name | transmembrane p24 trafficking protein 6 |
| Synonyms | PRO34237,SPLL9146,p24g5 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome |
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TMED6 cDNA ORF clone, Homo sapiens(human)
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Gene
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Clones
gRNAs
The following TMED6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMED6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID OHu06377 Clone ID Related Accession (Same CDS sequence) NM_144676.3 , NM_144676.4 Accession Version NM_144676.3 Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1506787200000 Organism Homo sapiens(human) Product transmembrane emp24 domain-containing protein 6 precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI600655.1, AY358268.1, BC020827.1 and AA804957.1. On Nov 25, 2009 this sequence version replaced NM_144676.2. ##Evidence-Data-START## Transcript exon combination :: BC020827.1, AY358268.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
1
61
121
181
241
301
361
421
481
541
601
661
721ATGTCCCCTT TGCTCTTTGG GGCTGGGCTG GTCGTTCTGA ATCTAGTGAC GTCTGCCAGG
AGCCAGAAGA CAGAACCTCT AAGTGGCTCT GGGGACCAGC CACTCTTCCG TGGAGCTGAT
CGATATGACT TTGCCATCAT GATACCTCCA GGAGGCACGG AATGCTTTTG GCAATTTGCC
CACCAGACTG GATACTTCTA TTTCAGTTAC GAGGTTCAGC GGACAGTGGG GATGTCACAT
GACCGGCATG TTGCTGCCAC GGCACATAAC CCACAGGGAT TTCTCATAGA CACCTCCCAG
GGTGTTCGGG GCCAGATTAA CTTCTCTACC CAAGAGACAG GTTTTTATCA GCTTTGTCTA
AGTAATCAGC ATAATCACTT CGGTTCTGTG CAAGTGTACC TCAACTTTGG GGTCTTCTAT
GAGGGGCCTG AGACTGATCA CAAACAGAAG GAAAGAAAAC AACTGAATGA TACTCTGGAT
GCAATTGAGG ACGGCACACA AAAGGTGCAG AACAATATCT TTCACATGTG GCGATACTAC
AACTTTGCCC GGATGAGGAA AATGGCTGAC TTTTTCCTTA TCCAATCAAA CTATAACTAC
GTGAACTGGT GGTCGACAGC CCAGAGCCTT GTTATTATTC TTTCTGGGAT CCTGCAACTG
TATTTCTTGA AGCGTCTCTT CAATGTTCCA ACAACTACAG ATACAAAGAA GCCAAGATGC
TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_653277.2 CDS 57..779 Translation 
Target ORF information:
RefSeq Version NM_144676.3 Organism Homo sapiens(human) Definition Homo sapiens transmembrane p24 trafficking protein 6 (TMED6), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_144676.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGTCCCCTT TGCTCTTTGG GGCTGGGCTG GTCGTTCTGA ATCTAGTGAC GTCTGCCAGG
AGCCAGAAGA CAGAACCTCT AAGTGGCTCT GGGGACCAGC CACTCTTCCG TGGAGCTGAT
CGATATGACT TTGCCATCAT GATACCTCCA GGAGGCACGG AATGCTTTTG GCAATTTGCC
CACCAGACTG GATACTTCTA TTTCAGTTAC GAGGTTCAGC GGACAGTGGG GATGTCACAT
GACCGGCATG TTGCTGCCAC GGCACATAAC CCACAGGGAT TTCTCATAGA CACCTCCCAG
GGTGTTCGGG GCCAGATTAA CTTCTCTACC CAAGAGACAG GTTTTTATCA GCTTTGTCTA
AGTAATCAGC ATAATCACTT CGGTTCTGTG CAAGTGTACC TCAACTTTGG GGTCTTCTAT
GAGGGGCCTG AGACTGATCA CAAACAGAAG GAAAGAAAAC AACTGAATGA TACTCTGGAT
GCAATTGAGG ACGGCACACA AAAGGTGCAG AACAATATCT TTCACATGTG GCGATACTAC
AACTTTGCCC GGATGAGGAA AATGGCTGAC TTTTTCCTTA TCCAATCAAA CTATAACTAC
GTGAACTGGT GGTCGACAGC CCAGAGCCTT GTTATTATTC TTTCTGGGAT CCTGCAACTG
TATTTCTTGA AGCGTCTCTT CAATGTTCCA ACAACTACAG ATACAAAGAA GCCAAGATGC
TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID OHu06377 Clone ID Related Accession (Same CDS sequence) NM_144676.3 , NM_144676.4 Accession Version NM_144676.4 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1556640000000 Organism Homo sapiens(human) Product transmembrane emp24 domain-containing protein 6 precursor Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI600655.1, AY358268.1, BC020827.1 and AA804957.1. On Nov 23, 2018 this sequence version replaced NM_144676.3. ##Evidence-Data-START## Transcript exon combination :: BC020827.1, BI600655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000288025.4/ ENSP00000288025.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.
1
61
121
181
241
301
361
421
481
541
601
661
721ATGTCCCCTT TGCTCTTTGG GGCTGGGCTG GTCGTTCTGA ATCTAGTGAC GTCTGCCAGG
AGCCAGAAGA CAGAACCTCT AAGTGGCTCT GGGGACCAGC CACTCTTCCG TGGAGCTGAT
CGATATGACT TTGCCATCAT GATACCTCCA GGAGGCACGG AATGCTTTTG GCAATTTGCC
CACCAGACTG GATACTTCTA TTTCAGTTAC GAGGTTCAGC GGACAGTGGG GATGTCACAT
GACCGGCATG TTGCTGCCAC GGCACATAAC CCACAGGGAT TTCTCATAGA CACCTCCCAG
GGTGTTCGGG GCCAGATTAA CTTCTCTACC CAAGAGACAG GTTTTTATCA GCTTTGTCTA
AGTAATCAGC ATAATCACTT CGGTTCTGTG CAAGTGTACC TCAACTTTGG GGTCTTCTAT
GAGGGGCCTG AGACTGATCA CAAACAGAAG GAAAGAAAAC AACTGAATGA TACTCTGGAT
GCAATTGAGG ACGGCACACA AAAGGTGCAG AACAATATCT TTCACATGTG GCGATACTAC
AACTTTGCCC GGATGAGGAA AATGGCTGAC TTTTTCCTTA TCCAATCAAA CTATAACTAC
GTGAACTGGT GGTCGACAGC CCAGAGCCTT GTTATTATTC TTTCTGGGAT CCTGCAACTG
TATTTCTTGA AGCGTCTCTT CAATGTTCCA ACAACTACAG ATACAAAGAA GCCAAGATGC
TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_653277.2 CDS 34..756 Translation
Target ORF information:
RefSeq Version NM_144676.4 Organism Homo sapiens(human) Definition Homo sapiens transmembrane p24 trafficking protein 6 (TMED6), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK NM_144676.4
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGTCCCCTT TGCTCTTTGG GGCTGGGCTG GTCGTTCTGA ATCTAGTGAC GTCTGCCAGG
AGCCAGAAGA CAGAACCTCT AAGTGGCTCT GGGGACCAGC CACTCTTCCG TGGAGCTGAT
CGATATGACT TTGCCATCAT GATACCTCCA GGAGGCACGG AATGCTTTTG GCAATTTGCC
CACCAGACTG GATACTTCTA TTTCAGTTAC GAGGTTCAGC GGACAGTGGG GATGTCACAT
GACCGGCATG TTGCTGCCAC GGCACATAAC CCACAGGGAT TTCTCATAGA CACCTCCCAG
GGTGTTCGGG GCCAGATTAA CTTCTCTACC CAAGAGACAG GTTTTTATCA GCTTTGTCTA
AGTAATCAGC ATAATCACTT CGGTTCTGTG CAAGTGTACC TCAACTTTGG GGTCTTCTAT
GAGGGGCCTG AGACTGATCA CAAACAGAAG GAAAGAAAAC AACTGAATGA TACTCTGGAT
GCAATTGAGG ACGGCACACA AAAGGTGCAG AACAATATCT TTCACATGTG GCGATACTAC
AACTTTGCCC GGATGAGGAA AATGGCTGAC TTTTTCCTTA TCCAATCAAA CTATAACTAC
GTGAACTGGT GGTCGACAGC CCAGAGCCTT GTTATTATTC TTTCTGGGAT CCTGCAACTG
TATTTCTTGA AGCGTCTCTT CAATGTTCCA ACAACTACAG ATACAAAGAA GCCAAGATGC
TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
TMED6-COG8 is a novel molecular marker of TFE3 translocation renal cell carcinoma.
International journal of clinical and experimental pathology8(3)2690-9(2015)
Xu Y,Rao Q,Xia Q,Shi S,Shi Q,Ma H,Lu Z,Chen H,Zhou X
Transmembrane emp24 protein transport domain 6 is selectively expressed in pancreatic islets and implicated in insulin secretion and diabetes.
Pancreas41(1)10-4(2012 Jan)
Wang X,Yang R,Jadhao SB,Yu D,Hu H,Glynn-Cunningham N,Sztalryd C,Silver KD,Gong DW
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A
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