crhbp cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	crhbp
Entrez Gene ID	445065
Full Name	corticotropin releasing hormone binding protein
Synonyms	zgc:91905
General protein information	Preferred Names corticotropin releasing hormone binding protein Names corticotropin-releasing factor-binding protein CRF-BP
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003459.1	NP_001003459.1	corticotropin-releasing factor-binding protein

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	CRHBP	XP_001106453.1
Mus musculus (house mouse)	Crhbp	NP_940800.1
Gallus gallus (chicken)	CRHBP	XP_424801.3
Danio rerio (zebrafish)	crhbp	NP_001003459.1
Rattus norvegicus (Norway rat)	Crhbp	NP_631922.1
Drosophila melanogaster (fruit fly)	CG15537	NP_001097981.1
Xenopus tropicalis (tropical clawed frog)	crhbp	XP_002940913.1
Bos taurus (cattle)	CRHBP	NP_001094672.1
Homo sapiens (human)	CRHBP	NP_001873.2
Pan troglodytes (chimpanzee)	CRHBP	XP_001144864.1
Canis lupus familiaris (dog)	CRHBP	XP_853211.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000955	XP_309147.5

Gene Ontology
Bibliography

Related articles in PubMed

Developmental fluoxetine exposure in zebrafish reduces offspring basal cortisol concentration via life stage-dependent maternal transmission.
Martinez R, Vera-Chang MN, Haddad M, Zon J, Navarro-Martin L, Trudeau VL, Mennigen JA
PloS one14(2)e0212577(2019)

Transgenerational thyroid endocrine disruption induced by bisphenol S affects the early development of zebrafish offspring.
Wei P, Zhao F, Zhang X, Liu W, Jiang G, Wang H, Ru S
Environmental pollution (Barking, Essex : 1987)243(Pt B)800-808(2018 Dec)

Microcystin-LR affects the hypothalamic-pituitary-inter-renal (HPI) axis in early life stages (embryos and larvae) of zebrafish.
Chen L, Wang Y, Giesy JP, Chen F, Shi T, Chen J, Xie P
Environmental pollution (Barking, Essex : 1987)241540-548(2018 Oct)

Corticotropin-releasing factor regulates caspase-3 and may protect developing zebrafish from stress-induced apoptosis.
Alderman SL, Leishman EM, Fuzzen MLM, Bernier NJ
General and comparative endocrinology265207-213(2018 09)

Light regimes differentially affect baseline transcript abundance of stress-axis and (neuro)development-related genes in zebrafish (
van den Bos R, Zethof J, Flik G, Gorissen M
Biology open6(11)1692-1697(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following crhbp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the crhbp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37277	NM_001003459.1 Latest version!	Danio rerio corticotropin releasing hormone binding protein (crhbp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

crhbp ( NM_001003459.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001003459.1 Danio rerio corticotropin releasing hormone binding protein (crhbp), mRNA.

Price & Availability↑

CloneID	ODa37277
Clone ID Related Accession (Same CDS sequence)	NM_001003459.1
Accession Version	NM_001003459.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576252800000
Organism	Danio rerio(zebrafish)
Product	corticotropin-releasing factor-binding protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076472.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC076472.1, BC164122.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTCGGCCA CTTCGCGCGC GCAGCTGTGC TTCCTCCTGT TGAGCGTCAC GGCTCTCCGG 
GGACACGCGC GCTTTCTGGA CATGCAGGAT AACGAGATCA GCCCGGAAGG ATTATTATCT 
CTGCTGAGCT CTGAACTAAA GCGAGAGTTA CCAGAGGAGT TTGTGTACCG CCGAGCGCTC 
AGGTGTCTGG ATATGGTGGC CGTAGAGGGT CAGTTTACAT TCACAGCAGA GCGACCGCAG 
TTAAACTGCG CAGTGTTTTT CATCGGCGAA CCTACTGACG TTATCAGCAT CGAGTATGAT 
TCGGTCAACA TCGACTGCAG AGGAGGAGAT TTCATTAAGG TATTTGATGG CTGGGTGATG 
AAGGGTGAGA AGTTCCCCAG CTCGCAGGAT CATCCTCTCC CTCTGTATGA GCGTTACACT 
GATTACTGCG AAACTGGAGT GTCTCGACCA ATCGTACGTT CCTCTCAGAA CGTCGCCATG 
CTGTTCTTCA GGCTCCACCA ATCAGGAAGC AGCTTCACAG TAACATTTCG CAAACTCATC 
AATCCCTTCC CCTGTAATGT TGTGTCTCAG ACCCCAGAGG GCAGTTTCAC CATGATCATT 
CCTCAGCAGC ACAGGAACTG CAGCTTCTCC ATCATCTATC CAGTGGAGAT CCAGATTGGA 
GAGCTCAGCC TTGGACAGCA CAATGATCTC AAGAGGTCCA TTCTTGGCTG CGCTGGTTCT 
GGAGACTTTG TTGAGCTTCT TGGTGGAAAC GGCATGGACA CGTCTAAGAT GTTCCCAATG 
GCAGATCTCT GCTACTCCTT TAATGGACCA GCTCAAATGA AGGTCGGCTG TGATAACACT 
GTGGTCAGAA TGGTGTCGAG CGGGAAGTTC GTAAATCGAG TCAGTTTCCA GTATCGGCTA 
CTGGGCCACC AAGAGCTTCA GCAGATGAAG GGCAACAGTG TTGAAGACGT GTGTTTAAGA 
GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003459.1
CDS	39..1004
Translation	MSATSRAQLCFLLLSVTALRGHARFLDMQDNEISPEGLLSLLSSELKRELPEEFVYRRALRCLDMVAVEGQFTFTAERPQLNCAVFFIGEPTDVISIEYDSVNIDCRGGDFIKVFDGWVMKGEKFPSSQDHPLPLYERYTDYCETGVSRPIVRSSQNVAMLFFRLHQSGSSFTVTFRKLINPFPCNVVSQTPEGSFTMIIPQQHRNCSFSIIYPVEIQIGELSLGQHNDLKRSILGCAGSGDFVELLGGNGMDTSKMFPMADLCYSFNGPAQMKVGCDNTVVRMVSSGKFVNRVSFQYRLLGHQELQQMKGNSVEDVCLRA

Target ORF information:

RefSeq Version	NM_001003459.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio corticotropin releasing hormone binding protein (crhbp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003459.1

ORF Insert Sequence:

ATGTCGGCCA CTTCGCGCGC GCAGCTGTGC TTCCTCCTGT TGAGCGTCAC GGCTCTCCGG 
GGACACGCGC GCTTTCTGGA CATGCAGGAT AACGAGATCA GCCCGGAAGG ATTATTATCT 
CTGCTGAGCT CTGAACTAAA GCGAGAGTTA CCAGAGGAGT TTGTGTACCG CCGAGCGCTC 
AGGTGTCTGG ATATGGTGGC CGTAGAGGGT CAGTTTACAT TCACAGCAGA GCGACCGCAG 
TTAAACTGCG CAGTGTTTTT CATCGGCGAA CCTACTGACG TTATCAGCAT CGAGTATGAT 
TCGGTCAACA TCGACTGCAG AGGAGGAGAT TTCATTAAGG TATTTGATGG CTGGGTGATG 
AAGGGTGAGA AGTTCCCCAG CTCGCAGGAT CATCCTCTCC CTCTGTATGA GCGTTACACT 
GATTACTGCG AAACTGGAGT GTCTCGACCA ATCGTACGTT CCTCTCAGAA CGTCGCCATG 
CTGTTCTTCA GGCTCCACCA ATCAGGAAGC AGCTTCACAG TAACATTTCG CAAACTCATC 
AATCCCTTCC CCTGTAATGT TGTGTCTCAG ACCCCAGAGG GCAGTTTCAC CATGATCATT 
CCTCAGCAGC ACAGGAACTG CAGCTTCTCC ATCATCTATC CAGTGGAGAT CCAGATTGGA 
GAGCTCAGCC TTGGACAGCA CAATGATCTC AAGAGGTCCA TTCTTGGCTG CGCTGGTTCT 
GGAGACTTTG TTGAGCTTCT TGGTGGAAAC GGCATGGACA CGTCTAAGAT GTTCCCAATG 
GCAGATCTCT GCTACTCCTT TAATGGACCA GCTCAAATGA AGGTCGGCTG TGATAACACT 
GTGGTCAGAA TGGTGTCGAG CGGGAAGTTC GTAAATCGAG TCAGTTTCCA GTATCGGCTA 
CTGGGCCACC AAGAGCTTCA GCAGATGAAG GGCAACAGTG TTGAAGACGT GTGTTTAAGA 
GCATAA