htr1aa cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	htr1aa
Entrez Gene ID	100001828
Full Name	5-hydroxytryptamine (serotonin) receptor 1A a
Synonyms	htr1a
General protein information	Preferred Names 5-hydroxytryptamine (serotonin) receptor 1A a Names 5-hydroxytryptamine receptor 1A
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001123321.1	NP_001116793.1	5-hydroxytryptamine receptor 1A

Pathways from BioSystems

Homologies

Homo sapiens (human)	HTR1A	NP_000515.2
Mus musculus (house mouse)	Htr1a	NP_032334.2
Gallus gallus (chicken)	HTR1A	NP_001163999.1
Anopheles gambiae (African malaria mosquito)	GPR5HT1A	XP_308623.4
Pan troglodytes (chimpanzee)	HTR1A	NP_001129094.1
Canis lupus familiaris (dog)	HTR1A	NP_001012397.1
Xenopus tropicalis (tropical clawed frog)	htr1a	XP_004910432.1
Bos taurus (cattle)	HTR1A	XP_002696350.1
Drosophila melanogaster (fruit fly)	5-HT1A	NP_725849.1
Caenorhabditis elegans (roundworm)	ser-4	NP_497452.1
Danio rerio (zebrafish)	htr1aa	NP_001116793.1
Rattus norvegicus (Norway rat)	Htr1a	NP_036717.1
Macaca mulatta (Rhesus monkey)	HTR1A	XP_001083407.1

Gene Ontology
Bibliography

Related articles in PubMed

Chronic exposure to dietary selenomethionine dysregulates the genes involved in serotonergic neurotransmission and alters social and antipredator behaviours in zebrafish (Danio rerio).
Attaran A, Salahinejad A, Crane AL, Niyogi S, Chivers DP
Environmental pollution (Barking, Essex : 1987)246837-844(2019 Mar)

NK1R/5-HT1AR interaction is related to the regulation of melanogenesis.
Wu H, Zhao Y, Huang Q, Cai M, Pan Q, Fu M, An X, Xia Z, Liu M, Jin Y, He L, Shang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology32(6)3193-3214(2018 06)

Fluoxetine modulates the transcription of genes involved in serotonin, dopamine and adrenergic signalling in zebrafish embryos.
Cunha V, Rodrigues P, Santos MM, Moradas-Ferreira P, Ferreira M
Chemosphere191954-961(2018 Jan)

Parental transfer of microcystin-LR induced transgenerational effects of developmental neurotoxicity in zebrafish offspring.
Wu Q, Yan W, Cheng H, Liu C, Hung TC, Guo X, Li G
Environmental pollution (Barking, Essex : 1987)231(Pt 1)471-478(2017 Dec)

Acute Exposure to Fluoxetine Alters Aggressive Behavior of Zebrafish and Expression of Genes Involved in Serotonergic System Regulation.
Theodoridi A, Tsalafouta A, Pavlidis M
Frontiers in neuroscience11223(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following htr1aa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the htr1aa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa35861	NM_001123321.1 Latest version!	Danio rerio 5-hydroxytryptamine (serotonin) receptor 1A a (htr1aa), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

htr1aa ( NM_001123321.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001116793.1 Danio rerio 5-hydroxytryptamine (serotonin) receptor 1A a (htr1aa), mRNA.

Price & Availability↑

CloneID	ODa35861
Clone ID Related Accession (Same CDS sequence)	NM_001123321.1
Accession Version	NM_001123321.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1197bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573228800000
Organism	Danio rerio(zebrafish)
Product	5-hydroxytryptamine receptor 1A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BX571721.8. On Apr 11, 2008 this sequence version replaced XM_001341716.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: GFIL01013015.1 [ECO:0000345] ##Evidence-Data-END##

ATGGAGAGCT ACAACAACAC CACAGAAAGC CAAGATTGGA GCGGGAACGC GACGAGTGTC 
AGCGAAGTTG CTCTGAGTTA CCAAATCATC GGCTCGCTTT TCCTGGCCGC GTTAATTCTG 
TTTGCCATTT TGGGAAACGC GTGTGTCATC GCTGCTATCG CCTTGGAGAG ATCGCTTCAG 
AATGTGGCCA ACTATCTCAT CGGCTCCCTG GCCGTTACAG ACCTTATGGT GTCGGTGCTG 
GTGCTCCCCA TGGCAGCCCT GTATCAGGTT TTGAATAAAT GGACTTTGGG ACAGGAGATG 
TGCGATATTT TCATCTCTCT AGACGTGCTG TGCTGCACTT CTTCCATCCT GCACCTGTGC 
GCAATCGCTT TGGATAGGTA CTGGGCCATC ACCGATCCCA TAGACTACGT GAATAAAAGG 
ACGCCCAGAC GAGCTGCTAT CTTGATCAGT CTCACTTGGC TAATAGGATT TTCCATTTCC 
ATTCCGCCCA TGTTGGGTTG GAGGAAACCG GAGGACCGGG CAGATCCCGA CGCGTGCACA 
ATCAGCCAGG ACCACGGGTA CACCATCTAC TCAACTTTCG GGGCGTTCTA CATCCCGCTC 
ATCCTCATGC TGGTCCTTTA CGGACGGATA TTCCGAGCGG CGAGGTTTCG CATAAGGAAA 
ACGGTAAAGA AAACGGAGAA AGCGAAAATC GCGGATAAAT GCTTGGCGGT GTCTCCAGCG 
CTCTTCCCGA GGAAAGCGAA CGGAGAGGTG GGTAAAACTT GGAGGCGAAG CGTGGAGCCG 
TGCGCAAACG GCGCGCTGAA AAACTCGGAC GACGGAGAGT CGTTCGAGAT TACAGAAGTT 
CAAAGCATCT CCAAAAATCA CCTGAGCCTG CCAAACAACC CTCAGCCGTG CTTCGAGAAC 
CGAAATGAGA AAAACACGGA AGCGAAGCGC AAAGTGGCTC TGGCCAGAGA ACGCAAAACA 
GTCAAGACTC TGGGAATAAT CATGGGCACG TTTATTTTCT GCTGGCTGCC CTTCTTCATC 
GTAGCGCTCG TGTTGCCTTT TTGTCAGGAC TGTTTTATGC CCGAATGGTT GGGCGCTGTC 
ATAAACTGGC TCGGATACTC CAACTCACTT TTGAATCCTG TCATATATGC GTACTTCAAT 
AAAGACTTTC AGAACGCATT CAAGAAGATT TTGAAATGCA AATGTATTAG ACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116793.1
CDS	103..1299
Translation	MESYNNTTESQDWSGNATSVSEVALSYQIIGSLFLAALILFAILGNACVIAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQEMCDIFISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAILISLTWLIGFSISIPPMLGWRKPEDRADPDACTISQDHGYTIYSTFGAFYIPLILMLVLYGRIFRAARFRIRKTVKKTEKAKIADKCLAVSPALFPRKANGEVGKTWRRSVEPCANGALKNSDDGESFEITEVQSISKNHLSLPNNPQPCFENRNEKNTEAKRKVALARERKTVKTLGIIMGTFIFCWLPFFIVALVLPFCQDCFMPEWLGAVINWLGYSNSLLNPVIYAYFNKDFQNAFKKILKCKCIRQ

Target ORF information:

RefSeq Version	NM_001123321.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio 5-hydroxytryptamine (serotonin) receptor 1A a (htr1aa), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001123321.1

ORF Insert Sequence:

ATGGAGAGCT ACAACAACAC CACAGAAAGC CAAGATTGGA GCGGGAACGC GACGAGTGTC 
AGCGAAGTTG CTCTGAGTTA CCAAATCATC GGCTCGCTTT TCCTGGCCGC GTTAATTCTG 
TTTGCCATTT TGGGAAACGC GTGTGTCATC GCTGCTATCG CCTTGGAGAG ATCGCTTCAG 
AATGTGGCCA ACTATCTCAT CGGCTCCCTG GCCGTTACAG ACCTTATGGT GTCGGTGCTG 
GTGCTCCCCA TGGCAGCCCT GTATCAGGTT TTGAATAAAT GGACTTTGGG ACAGGAGATG 
TGCGATATTT TCATCTCTCT AGACGTGCTG TGCTGCACTT CTTCCATCCT GCACCTGTGC 
GCAATCGCTT TGGATAGGTA CTGGGCCATC ACCGATCCCA TAGACTACGT GAATAAAAGG 
ACGCCCAGAC GAGCTGCTAT CTTGATCAGT CTCACTTGGC TAATAGGATT TTCCATTTCC 
ATTCCGCCCA TGTTGGGTTG GAGGAAACCG GAGGACCGGG CAGATCCCGA CGCGTGCACA 
ATCAGCCAGG ACCACGGGTA CACCATCTAC TCAACTTTCG GGGCGTTCTA CATCCCGCTC 
ATCCTCATGC TGGTCCTTTA CGGACGGATA TTCCGAGCGG CGAGGTTTCG CATAAGGAAA 
ACGGTAAAGA AAACGGAGAA AGCGAAAATC GCGGATAAAT GCTTGGCGGT GTCTCCAGCG 
CTCTTCCCGA GGAAAGCGAA CGGAGAGGTG GGTAAAACTT GGAGGCGAAG CGTGGAGCCG 
TGCGCAAACG GCGCGCTGAA AAACTCGGAC GACGGAGAGT CGTTCGAGAT TACAGAAGTT 
CAAAGCATCT CCAAAAATCA CCTGAGCCTG CCAAACAACC CTCAGCCGTG CTTCGAGAAC 
CGAAATGAGA AAAACACGGA AGCGAAGCGC AAAGTGGCTC TGGCCAGAGA ACGCAAAACA 
GTCAAGACTC TGGGAATAAT CATGGGCACG TTTATTTTCT GCTGGCTGCC CTTCTTCATC 
GTAGCGCTCG TGTTGCCTTT TTGTCAGGAC TGTTTTATGC CCGAATGGTT GGGCGCTGTC 
ATAAACTGGC TCGGATACTC CAACTCACTT TTGAATCCTG TCATATATGC GTACTTCAAT 
AAAGACTTTC AGAACGCATT CAAGAAGATT TTGAAATGCA AATGTATTAG ACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chronic exposure to dietary selenomethionine dysregulates the genes involved in serotonergic neurotransmission and alters social and antipredator behaviours in zebrafish (Danio rerio).
Environmental pollution (Barking, Essex : 1987)246837-844(2019 Mar)
Attaran A,Salahinejad A,Crane AL,Niyogi S,Chivers DP

NK1R/5-HT1AR interaction is related to the regulation of melanogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology32(6)3193-3214(2018 06)
Wu H,Zhao Y,Huang Q,Cai M,Pan Q,Fu M,An X,Xia Z,Liu M,Jin Y,He L,Shang J

Fluoxetine modulates the transcription of genes involved in serotonin, dopamine and adrenergic signalling in zebrafish embryos.
Chemosphere191954-961(2018 Jan)
Cunha V,Rodrigues P,Santos MM,Moradas-Ferreira P,Ferreira M

Parental transfer of microcystin-LR induced transgenerational effects of developmental neurotoxicity in zebrafish offspring.
Environmental pollution (Barking, Essex : 1987)231(Pt 1)471-478(2017 Dec)
Wu Q,Yan W,Cheng H,Liu C,Hung TC,Guo X,Li G

Acute Exposure to Fluoxetine Alters Aggressive Behavior of Zebrafish and Expression of Genes Involved in Serotonergic System Regulation.
Frontiers in neuroscience11223(2017)
Theodoridi A,Tsalafouta A,Pavlidis M