Htr1a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Htr1a
Entrez Gene ID	15550
Full Name	5-hydroxytryptamine (serotonin) receptor 1A
Synonyms	Gpcr18
General protein information	Preferred Names 5-hydroxytryptamine (serotonin) receptor 1A Names 5-hydroxytryptamine receptor 1A 5-HT-1A 5-HT1A receptor G-protein coupled receptor 18 serotonin receptor 1A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13 D1\|13 56.92 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_008308.4	NP_032334.2	5-hydroxytryptamine receptor 1A

Pathways from BioSystems

Homologies

Homo sapiens (human)	HTR1A	NP_000515.2
Mus musculus (house mouse)	Htr1a	NP_032334.2
Gallus gallus (chicken)	HTR1A	NP_001163999.1
Anopheles gambiae (African malaria mosquito)	GPR5HT1A	XP_308623.4
Pan troglodytes (chimpanzee)	HTR1A	NP_001129094.1
Canis lupus familiaris (dog)	HTR1A	NP_001012397.1
Xenopus tropicalis (tropical clawed frog)	htr1a	XP_004910432.1
Bos taurus (cattle)	HTR1A	XP_002696350.1
Drosophila melanogaster (fruit fly)	5-HT1A	NP_725849.1
Caenorhabditis elegans (roundworm)	ser-4	NP_497452.1
Danio rerio (zebrafish)	htr1aa	NP_001116793.1
Rattus norvegicus (Norway rat)	Htr1a	NP_036717.1
Macaca mulatta (Rhesus monkey)	HTR1A	XP_001083407.1

Gene Ontology
Bibliography

Related articles in PubMed

5-HT1A autoreceptor in dorsal raphe nucleus mediates sensitization of conditioned place preference to cocaine in mice experienced with chronic pain.
Li Y, Zhu J, Zheng Q, Qian Z, Zhang L, Wei C, Han J, Liu Z, Ren W
Neuroreport30(9)681-687(2019 06)

MicroRNA-26a-2 maintains stress resiliency and antidepressant efficacy by targeting the serotonergic autoreceptor HTR1A.
Xie L, Chen J, Ding YM, Gui XW, Wu LX, Tian S, Wu W
Biochemical and biophysical research communications511(2)440-446(2019 04)

Role of hippocampal 5-HT1A receptors in the antidepressant-like phenotype of mice expressing RGS-insensitive Gαi2 protein.
Senese NB, Oginsky M, Neubig RR, Ferrario C, Jutkiewicz EM, Traynor JR
Neuropharmacology141296-304(2018 10)

Interplay between 5-HT
Baptista-de-Souza D, Pelarin V, Canto-de-Souza L, Nunes-de-Souza RL, Canto-de-Souza A
Neuropharmacology140100-106(2018 09)

Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture.
Saito YC, Tsujino N, Abe M, Yamazaki M, Sakimura K, Sakurai T
Frontiers in neuroscience12892(2018)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Htr1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Htr1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18163	NM_008308.4 Latest version!	Mus musculus 5-hydroxytryptamine (serotonin) receptor 1A (Htr1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Htr1a ( NM_008308.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032334.2 Mus musculus 5-hydroxytryptamine (serotonin) receptor 1A (Htr1a), mRNA.

Price & Availability↑

CloneID	OMu18163
Clone ID Related Accession (Same CDS sequence)	NM_008308.4
Accession Version	NM_008308.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1266bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Mus musculus(house mouse)
Product	5-hydroxytryptamine receptor 1A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY239730.1, AK049884.1 and BY601671.1. On Dec 7, 2007 this sequence version replaced NM_008308.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGATATGT TCAGTCTTGG CCAGGGCAAC AACACCACAA CGTCCCTGGA GCCCTTCGGG 
ACAGGCGGCA ACGATACTGG CCTCTCCAAC GTGACCTTCA GCTACCAAGT GATCACCTCT 
CTTTTGCTGG GGACGCTCAT TTTCTGCGCG GTGCTCGGCA ATGCCTGCGT GGTTGCTGCC 
ATCGCCCTGG AGCGCTCCCT TCAGAATGTT GCCAACTATC TCATCGGCTC CTTGGCGGTC 
ACCGATCTCA TGGTGTCAGT GCTGGTGCTG CCCATGGCTG CTCTGTACCA GGTGCTCAAC 
AAGTGGACTC TGGGTCAGGT CACCTGTGAC CTGTTTATCG CCCTGGATGT GCTGTGCTGC 
ACTTCGTCCA TCCTGCACCT GTGCGCCATC GCGCTAGACA GGTACTGGGC AATCACCGAC 
CCTATAGACT ACGTGAACAA GAGGACGCCC CGGCGCGCCG CTGCGCTGAT CTCGCTCACT 
TGGCTCATTG GCTTTCTCAT CTCCATCCCG CCTATGCTGG GCTGGCGCAC CCCGGAAGAC 
CGCTCGAACC CCAACGAGTG CACCATCAGC AAGGACCACG GGTACACCAT CTACTCCACT 
TTCGGCGCTT TCTATATTCC GCTGCTGCTC ATGCTGGTCC TCTATGGGCG CATCTTCAGA 
GCCGCGCGCT TCCGAATCCG CAAGACGGTC AAGAAGGTGG AAAAGAAGGG AGCGGGCACC 
AGCTTCGGAA CATCGTCGGC CCCGCCCCCC AAGAAGAGCC TGAATGGTCA GCCAGGTAGT 
GGGGACTGCA GGCGCAGTGC TGAGAACAGG GCGGTGGGGA CTCCGTGCGC TAATGGGGCG 
GTGAGACAGG GTGAGGACGA CGCCACCCTG GAGGTGATCG AGGTGCATCG AGTGGGCAAC 
TCCAAAGGGC ACCTTCCTCT GCCCAGCGAA TCAGGAGCTA CCTCCTATGT CCCCGCCTGC 
TTGGAGAGAA AAAATGAGCG CACTGCTGAG GCAAAGCGCA AGATGGCCTT GGCCCGTGAG 
AGGAAGACAG TGAAGACACT GGGCATCATC ATGGGCACCT TCATCCTCTG CTGGCTGCCC 
TTTTTCATTG TGGCCCTGGT CCTACCTTTC TGTGAGAGCA GTTGCCACAT GCCTGAGTTG 
TTGGGTGCCA TAATTAACTG GCTAGGCTAC TCCAACTCCC TGCTCAACCC AGTTATTTAT 
GCTTATTTCA ACAAAGACTT TCAAAACGCT TTTAAGAAGA TCATCAAGTG CAAGTTCTGC 
CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032334.2
CDS	562..1827
Translation	MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR

Target ORF information:

RefSeq Version	NM_008308.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus 5-hydroxytryptamine (serotonin) receptor 1A (Htr1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008308.4

ORF Insert Sequence:

ATGGATATGT TCAGTCTTGG CCAGGGCAAC AACACCACAA CGTCCCTGGA GCCCTTCGGG 
ACAGGCGGCA ACGATACTGG CCTCTCCAAC GTGACCTTCA GCTACCAAGT GATCACCTCT 
CTTTTGCTGG GGACGCTCAT TTTCTGCGCG GTGCTCGGCA ATGCCTGCGT GGTTGCTGCC 
ATCGCCCTGG AGCGCTCCCT TCAGAATGTT GCCAACTATC TCATCGGCTC CTTGGCGGTC 
ACCGATCTCA TGGTGTCAGT GCTGGTGCTG CCCATGGCTG CTCTGTACCA GGTGCTCAAC 
AAGTGGACTC TGGGTCAGGT CACCTGTGAC CTGTTTATCG CCCTGGATGT GCTGTGCTGC 
ACTTCGTCCA TCCTGCACCT GTGCGCCATC GCGCTAGACA GGTACTGGGC AATCACCGAC 
CCTATAGACT ACGTGAACAA GAGGACGCCC CGGCGCGCCG CTGCGCTGAT CTCGCTCACT 
TGGCTCATTG GCTTTCTCAT CTCCATCCCG CCTATGCTGG GCTGGCGCAC CCCGGAAGAC 
CGCTCGAACC CCAACGAGTG CACCATCAGC AAGGACCACG GGTACACCAT CTACTCCACT 
TTCGGCGCTT TCTATATTCC GCTGCTGCTC ATGCTGGTCC TCTATGGGCG CATCTTCAGA 
GCCGCGCGCT TCCGAATCCG CAAGACGGTC AAGAAGGTGG AAAAGAAGGG AGCGGGCACC 
AGCTTCGGAA CATCGTCGGC CCCGCCCCCC AAGAAGAGCC TGAATGGTCA GCCAGGTAGT 
GGGGACTGCA GGCGCAGTGC TGAGAACAGG GCGGTGGGGA CTCCGTGCGC TAATGGGGCG 
GTGAGACAGG GTGAGGACGA CGCCACCCTG GAGGTGATCG AGGTGCATCG AGTGGGCAAC 
TCCAAAGGGC ACCTTCCTCT GCCCAGCGAA TCAGGAGCTA CCTCCTATGT CCCCGCCTGC 
TTGGAGAGAA AAAATGAGCG CACTGCTGAG GCAAAGCGCA AGATGGCCTT GGCCCGTGAG 
AGGAAGACAG TGAAGACACT GGGCATCATC ATGGGCACCT TCATCCTCTG CTGGCTGCCC 
TTTTTCATTG TGGCCCTGGT CCTACCTTTC TGTGAGAGCA GTTGCCACAT GCCTGAGTTG 
TTGGGTGCCA TAATTAACTG GCTAGGCTAC TCCAACTCCC TGCTCAACCC AGTTATTTAT 
GCTTATTTCA ACAAAGACTT TCAAAACGCT TTTAAGAAGA TCATCAAGTG CAAGTTCTGC 
CGCTGA