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a Related Biological Terms:

direct calorimetry

Evaluation of the heat evolved by a human or experimental animal by measurement of the heat exchanged with the environment in specially constructed insulated chambers. (see also indirect calorimetry)

direct van den Bergh reaction

(see van den Bergh reaction)

directed proton transfer

(see entropy effect)

discontinuous transcription

see trans-splicing

disease gene mapping

The localization of a specific gene to a locus on a chromosome by study of the morphology of chromosomes and by linkage studies.

displacement chromatography

A column chromatographic method for separation and concentration of components of a solution. After adsorption of the sample to be separated on to the resin in a column, all bound molecules are displaced by a concentrated solution of a displacer, whose affinity for the stationary phase must be higher than that of any of the sample molecules. As the displacer sweeps the adsorbed molecules ahead of itself, each of these becomes a displacer for any molecule of lower affinity. Thus the original components are eluted in small volumes ahead of the displacer, in reverse order with regard to their affinities for the stationary phase. Learn more about genetic code table.

dissociation constant (Kd)

Given by [A][B]/[AB], where [AB]=[A]+[B]; expressed in units of concentration. (see also association constant (Ka); pKa)

dogma

(see central dogma)

domain

A region of a globular protein that has its own tertiary structure, and that is stable independently of the rest of the protein; often connected to other domains of the same protein by short sequences without secondary structure.

domain boundary model

see insulator

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