Gfra3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gfra3
Entrez Gene ID	84422
Full Name	GDNF family receptor alpha 3
General protein information	Preferred Names GDNF family receptor alpha 3 Names GDNF family receptor alpha-3 glial cell line derived neurotrophic factor family receptor alpha 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18p12
Summary	responsible for neuronal cell protection and cell survival in the inner ear [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053398.1	NP_445850.1	GDNF family receptor alpha-3 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	GFRA3	NP_001487.2
Canis lupus familiaris (dog)	GFRA3	XP_005626660.1
Pan troglodytes (chimpanzee)	GFRA3	XP_517954.2
Macaca mulatta (Rhesus monkey)	GFRA3	XP_001112630.1
Mus musculus (house mouse)	Gfra3	NP_034410.3
Rattus norvegicus (Norway rat)	Gfra3	NP_445850.1
Bos taurus (cattle)	GFRA3	NP_001077216.1

Gene Ontology
Bibliography

Related articles in PubMed

Artemin-GFRα3 interactions partially contribute to acute inflammatory hypersensitivity.
Thornton P, Hatcher JP, Robinson I, Sargent B, Franzén B, Martino G, Kitching L, Glover CP, Anderson D, Forsmo-Bruce H, Low CP, Cusdin F, Dosanjh B, Williams W, Steffen AC, Thompson S, Eklund M, Lloyd C, Chessell I, Hughes J
Neuroscience letters54523-8(2013 Jun)

Expression of receptors for glial cell line-derived neurotrophic factor family ligands in sacral spinal cord reveals separate targets of pelvic afferent fibers.
Forrest SL, Keast JR
The Journal of comparative neurology506(6)989-1002(2008 Feb)

Distribution of GDNF family receptor alpha3 and RET in rat and human non-neural tissues.
Yang C, Hutto D, Sah DW
Journal of molecular histology37(1-2)69-77(2006 Jan)

Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons.
Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E, Milbrandt J
Neuron35(2)267-82(2002 Jul)

Expression of glial cell line-derived neurotrophic factor family of growth factors in peripheral nerve injury in rats.
Höke A, Cheng C, Zochodne DW
Neuroreport11(8)1651-4(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gfra3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gfra3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09444	NM_053398.1 Latest version!	Rattus norvegicus GDNF family receptor alpha 3 (Gfra3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gfra3 ( NM_053398.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445850.1 Rattus norvegicus GDNF family receptor alpha 3 (Gfra3), mRNA.

Price & Availability↑

CloneID	ORa09444
Clone ID Related Accession (Same CDS sequence)	NM_053398.1
Accession Version	NM_053398.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527264000000
Organism	Rattus norvegicus(Norway rat)
Product	GDNF family receptor alpha-3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079378.1. On Apr 19, 2005 this sequence version replaced XM_341593.2. ##Evidence-Data-START## Transcript exon combination :: BC079378.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGCTCT CCCGGAGCCC GCGACCGCCG CCGCTAGTGA TCCTGCTACT GGTGCTGTCG 
CTGTGGCTAC CCCTTGGAAC AGGAAACTCC CTTCCCACAG AGAACAGGCT TGTGAACAGC 
TGTACCCAGG CCAGAAAAAA ATGCGAGGCT AATCCCGCTT GCAAGGCTGC CTACCAGCAC 
CTGGACTCCT GCACCCCCAG TCTCAGCAGT CCACTGCCCT CAGGGGAGTC TGCCACATCT 
GCAGCGTGCC TTGAAGCAGC ACAGCAACTC AGGAACAGCT CTCTCATAGA CTGCAGGTGC 
CACCGGCGCA TGAAGCACCA AGCTACCTGT CTGGACATTT ATTGGACCGT TCACCCTGTC 
CGAAGCCTTG GTGACTACGA GTTGGACGTC TCACCCTATG AAGACACAGT GACCAGCAAA 
CCCTGGAAAA TGAATCTCAG CAAGCTGAGC ATGCTCAAAC CAGACTCCGA CCTCTGCCTC 
AAATTTGCTA TGCTGTGTAC TCTTAACGAC AAGTGCGACC GCCTCCGAAA GGCCTACGGG 
GAGGCGTGCT CAGGGATCCG CTGCCAGCGC CACCTCTGCC TAGCTCAGCT GCGCTCCTTC 
TTCGAGAAGG CGGCAGAGTC CCACGCTCAG GGCCTGCTGC TGTGTCCCTG TGCACCCGAA 
GATGCGGGCT GTGGGGAGCG CCGGCGCAAC ACCATCGCCC CCAGTTGCGC CCTCCCGTCT 
GTGGCCCCCA ACTGCCTAGA TCTTCGGAGC TTCTGCCGTG CGGACCCTCT GTGCAGATCA 
CGCCTGATGG ACTTCCAGAC CCACTGCCAC CCTATGGACA TCCTCGGGAC TTGTGCAACT 
GAGCAGTCCA GATGTCTGCG GGCATACCTG GGGCTAATTG GGACTGCCAT GACCCCAAAC 
TTCATCAGCA AGGTCAACAC TACTGTTGCC TTAGGCTGTA CCTGCCGAGG CAGTGGCAAC 
CTGCAGGACG AGTGTGAACA GCTGGAAAAG TCCTTCTCCC AGAACCCCTG CCTCATGGAG 
GCCATTGCGG CTAAAATGCG TTTCCACAGA CAACTCTTCT CCCAGGACTG GGCGGACTCT 
ACTTTTTCTG TGATGCAGCA GCAGAACAGC AGCCCTGCTC TGAGGCCCCA GCTCAGGCTA 
CCCGTTCTGT CTTTCTTCAT CCTTACCTTG ATTCTGCTGC AGACCCTCTG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445850.1
CDS	57..1250
Translation	MGLSRSPRPPPLVILLLVLSLWLPLGTGNSLPTENRLVNSCTQARKKCEANPACKAAYQHLDSCTPSLSSPLPSGESATSAACLEAAQQLRNSSLIDCRCHRRMKHQATCLDIYWTVHPVRSLGDYELDVSPYEDTVTSKPWKMNLSKLSMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACSGIRCQRHLCLAQLRSFFEKAAESHAQGLLLCPCAPEDAGCGERRRNTIAPSCALPSVAPNCLDLRSFCRADPLCRSRLMDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFISKVNTTVALGCTCRGSGNLQDECEQLEKSFSQNPCLMEAIAAKMRFHRQLFSQDWADSTFSVMQQQNSSPALRPQLRLPVLSFFILTLILLQTLW

Target ORF information:

RefSeq Version	NM_053398.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus GDNF family receptor alpha 3 (Gfra3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053398.1

ORF Insert Sequence:

ATGGGGCTCT CCCGGAGCCC GCGACCGCCG CCGCTAGTGA TCCTGCTACT GGTGCTGTCG 
CTGTGGCTAC CCCTTGGAAC AGGAAACTCC CTTCCCACAG AGAACAGGCT TGTGAACAGC 
TGTACCCAGG CCAGAAAAAA ATGCGAGGCT AATCCCGCTT GCAAGGCTGC CTACCAGCAC 
CTGGACTCCT GCACCCCCAG TCTCAGCAGT CCACTGCCCT CAGGGGAGTC TGCCACATCT 
GCAGCGTGCC TTGAAGCAGC ACAGCAACTC AGGAACAGCT CTCTCATAGA CTGCAGGTGC 
CACCGGCGCA TGAAGCACCA AGCTACCTGT CTGGACATTT ATTGGACCGT TCACCCTGTC 
CGAAGCCTTG GTGACTACGA GTTGGACGTC TCACCCTATG AAGACACAGT GACCAGCAAA 
CCCTGGAAAA TGAATCTCAG CAAGCTGAGC ATGCTCAAAC CAGACTCCGA CCTCTGCCTC 
AAATTTGCTA TGCTGTGTAC TCTTAACGAC AAGTGCGACC GCCTCCGAAA GGCCTACGGG 
GAGGCGTGCT CAGGGATCCG CTGCCAGCGC CACCTCTGCC TAGCTCAGCT GCGCTCCTTC 
TTCGAGAAGG CGGCAGAGTC CCACGCTCAG GGCCTGCTGC TGTGTCCCTG TGCACCCGAA 
GATGCGGGCT GTGGGGAGCG CCGGCGCAAC ACCATCGCCC CCAGTTGCGC CCTCCCGTCT 
GTGGCCCCCA ACTGCCTAGA TCTTCGGAGC TTCTGCCGTG CGGACCCTCT GTGCAGATCA 
CGCCTGATGG ACTTCCAGAC CCACTGCCAC CCTATGGACA TCCTCGGGAC TTGTGCAACT 
GAGCAGTCCA GATGTCTGCG GGCATACCTG GGGCTAATTG GGACTGCCAT GACCCCAAAC 
TTCATCAGCA AGGTCAACAC TACTGTTGCC TTAGGCTGTA CCTGCCGAGG CAGTGGCAAC 
CTGCAGGACG AGTGTGAACA GCTGGAAAAG TCCTTCTCCC AGAACCCCTG CCTCATGGAG 
GCCATTGCGG CTAAAATGCG TTTCCACAGA CAACTCTTCT CCCAGGACTG GGCGGACTCT 
ACTTTTTCTG TGATGCAGCA GCAGAACAGC AGCCCTGCTC TGAGGCCCCA GCTCAGGCTA 
CCCGTTCTGT CTTTCTTCAT CCTTACCTTG ATTCTGCTGC AGACCCTCTG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Artemin-GFRα3 interactions partially contribute to acute inflammatory hypersensitivity.
Neuroscience letters54523-8(2013 Jun)
Thornton P,Hatcher JP,Robinson I,Sargent B,Franzén B,Martino G,Kitching L,Glover CP,Anderson D,Forsmo-Bruce H,Low CP,Cusdin F,Dosanjh B,Williams W,Steffen AC,Thompson S,Eklund M,Lloyd C,Chessell I,Hughes J

Expression of receptors for glial cell line-derived neurotrophic factor family ligands in sacral spinal cord reveals separate targets of pelvic afferent fibers.
The Journal of comparative neurology506(6)989-1002(2008 Feb)
Forrest SL,Keast JR

Distribution of GDNF family receptor alpha3 and RET in rat and human non-neural tissues.
Journal of molecular histology37(1-2)69-77(2006 Jan)
Yang C,Hutto D,Sah DW

Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons.
Neuron35(2)267-82(2002 Jul)
Honma Y,Araki T,Gianino S,Bruce A,Heuckeroth R,Johnson E,Milbrandt J

Expression of glial cell line-derived neurotrophic factor family of growth factors in peripheral nerve injury in rats.
Neuroreport11(8)1651-4(2000 Jun)
Höke A,Cheng C,Zochodne DW