| Gene Symbol | Hnmt |
| Entrez Gene ID | 81676 |
| Full Name | histamine N-methyltransferase |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | catalyzes the conversion of S-adenosyl-L-methionine and histamine to S-adenosyl-L-homocysteine and N(T) methylhistamine [RGD, Feb 2006]. |
- REAGENT SERVICES Hot!
-
PRODUCTS
-
Most Popular Reagents
-
Instruments
-
Antibodies
-
ELISA Kits
-
Protein Electrophoresis and Blotting
-
Protein and Antibody Purification
-
Recombinant Proteins
-
Molecular Biology
-
Stable Cell Lines
-
Cell Isolation and Activation
-
IVD Raw Materials
-
Therapy Applications
-
Resources
-
![AmMag™ Quatro Automated Plasmid Purification]()
AmMag™ Quatro automated plasmid purification
-
![Anti-Camelid VHH]()
MonoRab™ Anti-VHH Antibodies
-
![ELISA Kits]()
ELISA Kits
-
![Precast Gels]()
SurePAGE™ Precast Gels
-
![Quatro ProAb Automated Protein and Antibody Purification System]()
AmMag™ Quatro ProAb Automated Protein and Antibody Purification System
-
![Target Proteins]()
Target Proteins
-
![AmMag™ Quatro Automated Plasmid Purification]()
AmMag™ Quatro automated plasmid purification
-
![Stable Cell Lines]()
Stable Cell Lines
-
![Cell Isolation and Activation]()
Cell Isolation and Activation
-
![Quick
Order]()
Quick Order
-
![Quick
Order]()
Quick Order
- APPLICATIONS
- RESOURCES
- ABOUT US
Hnmt cDNA ORF clone, Rattus norvegicus(Norway rat)
-
Gene
-
Clones
gRNAs
The following Hnmt gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hnmt cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
-
Reference Sequences (Refseq)
CloneID ORa07451 Clone ID Related Accession (Same CDS sequence) NM_031044.3 Accession Version NM_031044.3 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 888bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1568908800000 Organism Rattus norvegicus(Norway rat) Product histamine N-methyltransferase Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D10693.1. On Jun 10, 2007 this sequence version replaced NM_031044.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D10693.1, BC087635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02642775 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGCATCTT TCATGAGGAG CTTATTTTCT GACCACAGCA GATATGTTGA ATCTTTTCGG
AGATTTCTAA ATAATTCAAC GGAACACCAG TGCATGCAGG AATTCATGGA TAAGAAGCTT
CCAGGCATAA TAGCAAGGAT TGGAGAAACA AAAGCAGAAA TTAAGATTCT GAGTATAGGC
GGAGGTGCAG GTGAAATTGA CCTTCAGATT CTCTCCAAAG TCCAGGCTCA GTACCCAGGA
ATCTGTATTA ACAATGAAGT TGTAGAGCCA AATGCCGAAC AAATTGTCAA GTACAAAGAG
CTTGTAGCAA AGACATCAAA CATGGAGAAC ATAAAATTTG CTTGGCATAA GGAGACATCA
TCTGAATATC AAAAACGTGT AGTGGAAGAA GACGAAGAAC CTCCAAAGTG GGACTTTATT
CATATGATTC AGATGCTATA TTATGTAAAG GATATCCCAG CCACCCTGAA ATTCTTCCAC
GGTCTCTTAG CTGCCAATGC TAAAATTCTC ATTATTCTTG TGTCAGGAAC TAGTGGCTGG
GAAAAGCTAT GGAAAAAATA TGGATTCCGC CTACCCAGGG ATGACCTCTG CCAGTATGTC
ACATCTTCTG ATCTTGCTCA GATACTGGAC GACCTGGGTA TTAAGTATGA ATGTTACGAC
CTTTTGTCCA CTATGGACAT AACAGACTGT TTTATTGATG GTAATGAAAA TGGAGACCTG
CTTTGGGATT TTTTGACAGA AACCTGCAAC TTTATCAAAA CAGCACCACT GGACCTCAAA
GAGGAAATTA TGAAAGATCT TCAAGAGCCT GAATTTAGTG TTAAGAAAGA GGGGAAGGTA
CTTTTCAACA ACAATCTGAG TTTTATAGTG GTTGAGGCAA ATGTATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_112306.1 CDS 9..896 Translation 
Target ORF information:
RefSeq Version NM_031044.3 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus histamine N-methyltransferase (Hnmt), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_031044.3
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGCATCTT TCATGAGGAG CTTATTTTCT GACCACAGCA GATATGTTGA ATCTTTTCGG
AGATTTCTAA ATAATTCAAC GGAACACCAG TGCATGCAGG AATTCATGGA TAAGAAGCTT
CCAGGCATAA TAGCAAGGAT TGGAGAAACA AAAGCAGAAA TTAAGATTCT GAGTATAGGC
GGAGGTGCAG GTGAAATTGA CCTTCAGATT CTCTCCAAAG TCCAGGCTCA GTACCCAGGA
ATCTGTATTA ACAATGAAGT TGTAGAGCCA AATGCCGAAC AAATTGTCAA GTACAAAGAG
CTTGTAGCAA AGACATCAAA CATGGAGAAC ATAAAATTTG CTTGGCATAA GGAGACATCA
TCTGAATATC AAAAACGTGT AGTGGAAGAA GACGAAGAAC CTCCAAAGTG GGACTTTATT
CATATGATTC AGATGCTATA TTATGTAAAG GATATCCCAG CCACCCTGAA ATTCTTCCAC
GGTCTCTTAG CTGCCAATGC TAAAATTCTC ATTATTCTTG TGTCAGGAAC TAGTGGCTGG
GAAAAGCTAT GGAAAAAATA TGGATTCCGC CTACCCAGGG ATGACCTCTG CCAGTATGTC
ACATCTTCTG ATCTTGCTCA GATACTGGAC GACCTGGGTA TTAAGTATGA ATGTTACGAC
CTTTTGTCCA CTATGGACAT AACAGACTGT TTTATTGATG GTAATGAAAA TGGAGACCTG
CTTTGGGATT TTTTGACAGA AACCTGCAAC TTTATCAAAA CAGCACCACT GGACCTCAAA
GAGGAAATTA TGAAAGATCT TCAAGAGCCT GAATTTAGTG TTAAGAAAGA GGGGAAGGTA
CTTTTCAACA ACAATCTGAG TTTTATAGTG GTTGAGGCAA ATGTATAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
-
PubMed
Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability.
Human molecular genetics24(20)5697-710(2015 Oct)
Heidari A,Tongsook C,Najafipour R,Musante L,Vasli N,Garshasbi M,Hu H,Mittal K,McNaughton AJ,Sritharan K,Hudson M,Stehr H,Talebi S,Moradi M,Darvish H,Arshad Rafiq M,Mozhdehipanah H,Rashidinejad A,Samiei S,Ghadami M,Windpassinger C,Gillessen-Kaesbach G,Tzschach A,Ahmed I,Mikhailov A,Stavropoulos DJ,Carter MT,Keshavarz S,Ayub M,Najmabadi H,Liu X,Ropers HH,Macheroux P,Vincent JB
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ
Functional increase of brain histaminergic signaling in Huntington's disease.
Brain pathology (Zurich, Switzerland)21(4)419-27(2011 Jul)
van Wamelen DJ,Shan L,Aziz NA,Anink JJ,Bao AM,Roos RA,Swaab DF
No association between histamine N-methyltransferase functional polymorphism Thr105Ile and Alzheimer's disease.
Neuroscience letters489(2)119-21(2011 Feb)
Marasović-Šušnjara I,Palada V,Marinović-Terzić I,Mimica N,Marin J,Muck-Seler D,Mustapić M,Presečki P,Pivac N,Folnegović-Šmalc V,Marinović-Ćurin J,Terzić J
Reduction of the infarct size by simultaneous administration of L-histidine and diphenhydramine in ischaemic rat brains.
Resuscitation82(2)219-21(2011 Feb)
Adachi N,Liu K,Ninomiya K,Matsuoka E,Motoki A,Irisawa Y,Nishibori M
-
-
Most Popular Services
-
Services & Products
-
News & Blogs
- An immunotoxin directed at regulatory T cells leads to long-lasting tumor regression
- Saving Crops from Powdery Mildew with CRISPR/Cas9 Gene Editing
- Does Hot Tea Really Cause Esophageal Cancer? Learn How Peptide Libraries Can Help
- Fetal Immune System Rejects Mother’s Womb, Leading to Preterm Labor
- Making CAR T Cells Safer with Synthetic Biology
- Borrow Nature’s Manufacturing Process for Complex Drug Production Using - Engineered Yeast
- Antiviral Nanoparticle Designed to Detect and Destroy a Broad Spectrum of Viruses
- Evolving CRISPR/Cas Tools through Engineering Strategies
-
-
-
PubMed
-
