HNMT gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_006895.3	NP_008826.1	histamine N-methyltransferase isoform 1
NM_001024074.2	NP_001019245.1	histamine N-methyltransferase isoform 2
XM_017003949.1	XP_016859438.1	histamine N-methyltransferase isoform X3
XM_017003949.2	XP_016859438.1	histamine N-methyltransferase isoform X3
NM_001024074.3	NP_001019245.1	histamine N-methyltransferase isoform 2
NM_006895.2	NP_008826.1	histamine N-methyltransferase isoform 1
NM_001024075.1	NP_001019246.1	histamine N-methyltransferase isoform 3
NM_001024075.2	NP_001019246.1	histamine N-methyltransferase isoform 3
XM_017003948.1	XP_016859437.1	histamine N-methyltransferase isoform X1
XM_011511064.2	XP_011509366.1	histamine N-methyltransferase isoform X2

The following HNMT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HNMT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04262	NM_001024075.2 Latest version!	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu58281	XM_017003948.1 Latest version!	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu58282	XM_011511064.2 Latest version!	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu89350	XM_017003949.2 Latest version!	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu11921	NM_001024074.3 Latest version!	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu18910	NM_006895.3 Latest version!	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu89350	XM_017003949.1	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu11921	NM_001024074.2	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu18910	NM_006895.2	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu04262	NM_001024075.1	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

Reference Sequences (Refseq)

HNMT ( NM_006895.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_008826.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18910
Clone ID Related Accession (Same CDS sequence)	NM_006895.3 , NM_006895.2
Accession Version	NM_006895.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1514217600000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093674.2, AF523358.1, AF523360.1 and AA935821.1. This sequence is a reference standard in the RefSeqGene project. On Jun 3, 2005 this sequence version replaced NM_006895.1. Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.172965.1, SRR1803612.259219.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAA TGCTGTATTA TGTAAAAGAC ATCCCAGCTA CCCTGAAATT CTTCCATAGT 
CTCTTAGGTA CCAATGCTAA GATGCTCATT ATTGTTGTGT CAGGAAGCAG TGGCTGGGAC 
AAGCTGTGGA AAAAGTACGG ATCACGCTTT CCCCAGGATG ACCTCTGCCA GTATATCACA 
TCAGATGACC TCACTCAGAT GCTGGACAAC CTAGGGCTTA AGTATGAGTG CTATGACCTT 
TTGTCCACCA TGGATATATC TGACTGCTTT ATTGATGGTA ATGAAAATGG AGACCTGCTT 
TGGGATTTTT TGACTGAAAC CTGCAACTTT AATGCCACAG CACCACCTGA TCTCAGAGCA 
GAGCTTGGGA AAGATCTACA AGAGCCTGAA TTTAGTGCTA AGAAAGAGGG GAAGGTTCTT 
TTTAATAATA CTCTGAGTTT CATAGTGATT GAGGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008826.1
CDS	255..1133
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA

Target ORF information:

RefSeq Version	NM_006895.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006895.2

ORF Insert Sequence:

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAA TGCTGTATTA TGTAAAAGAC ATCCCAGCTA CCCTGAAATT CTTCCATAGT 
CTCTTAGGTA CCAATGCTAA GATGCTCATT ATTGTTGTGT CAGGAAGCAG TGGCTGGGAC 
AAGCTGTGGA AAAAGTACGG ATCACGCTTT CCCCAGGATG ACCTCTGCCA GTATATCACA 
TCAGATGACC TCACTCAGAT GCTGGACAAC CTAGGGCTTA AGTATGAGTG CTATGACCTT 
TTGTCCACCA TGGATATATC TGACTGCTTT ATTGATGGTA ATGAAAATGG AGACCTGCTT 
TGGGATTTTT TGACTGAAAC CTGCAACTTT AATGCCACAG CACCACCTGA TCTCAGAGCA 
GAGCTTGGGA AAGATCTACA AGAGCCTGAA TTTAGTGCTA AGAAAGAGGG GAAGGTTCTT 
TTTAATAATA CTCTGAGTTT CATAGTGATT GAGGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( NM_001024075.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001019246.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu04262
Clone ID Related Accession (Same CDS sequence)	NM_001024075.1 , NM_001024075.2
Accession Version	NM_001024075.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1545408000000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093674.2 and AF523357.1. On Mar 29, 2008 this sequence version replaced XR_017842.2. Transcript Variant: This variant (3), also called HNMT-S, includes an alternate exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF523357.1, AF523356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG ATTGTCTCAT TCGGGGAAGC TCCAGGGTTC TCAAGCGGAA TTCGTGTTTC 
ATTTTGTGTA GCACCCGTCA GAAAGACAAG CCAGGCATGA GGATCCATGA TGAGCGCTCT 
TCTGAGTTGC CATTTGGAGC TGCCCGTTTA GAAAGCAAAT CTGCATTTCC CTCATTCCTA 
GTTTCCTTCA TCCTCTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019246.1
CDS	255..635
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELPFGAARLESKSAFPSFLVSFILF

Target ORF information:

RefSeq Version	NM_001024075.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024075.1

ORF Insert Sequence:

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG ATTGTCTCAT TCGGGGAAGC TCCAGGGTTC TCAAGCGGAA TTCGTGTTTC 
ATTTTGTGTA GCACCCGTCA GAAAGACAAG CCAGGCATGA GGATCCATGA TGAGCGCTCT 
TCTGAGTTGC CATTTGGAGC TGCCCGTTTA GAAAGCAAAT CTGCATTTCC CTCATTCCTA 
GTTTCCTTCA TCCTCTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( NM_001024075.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001019246.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu04262
Clone ID Related Accession (Same CDS sequence)	NM_001024075.1 , NM_001024075.2
Accession Version	NM_001024075.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574006400000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF523357.1. On May 31, 2019 this sequence version replaced NM_001024075.1. Transcript Variant: This variant (3), also called HNMT-S, includes an alternate exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF523357.1, AF523356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG ATTGTCTCAT TCGGGGAAGC TCCAGGGTTC TCAAGCGGAA TTCGTGTTTC 
ATTTTGTGTA GCACCCGTCA GAAAGACAAG CCAGGCATGA GGATCCATGA TGAGCGCTCT 
TCTGAGTTGC CATTTGGAGC TGCCCGTTTA GAAAGCAAAT CTGCATTTCC CTCATTCCTA 
GTTTCCTTCA TCCTCTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019246.1
CDS	20..400
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELPFGAARLESKSAFPSFLVSFILF

Target ORF information:

RefSeq Version	NM_001024075.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024075.2

ORF Insert Sequence:

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG ATTGTCTCAT TCGGGGAAGC TCCAGGGTTC TCAAGCGGAA TTCGTGTTTC 
ATTTTGTGTA GCACCCGTCA GAAAGACAAG CCAGGCATGA GGATCCATGA TGAGCGCTCT 
TCTGAGTTGC CATTTGGAGC TGCCCGTTTA GAAAGCAAAT CTGCATTTCC CTCATTCCTA 
GTTTCCTTCA TCCTCTTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( XM_017003948.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859437.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58281
Clone ID Related Accession (Same CDS sequence)	XM_017003948.1
Accession Version	XM_017003948.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGAGA CACTGCTCTC AGCCTGGATG ACAGAGATTG GAGACACAAA ATCAGAAATT 
AAGATTCTAA GCATAGGCGG AGGTGCAGGT GAAATTGATC TTCAAATTCT CTCCAAAGTT 
CAGGCTCAAT ACCCAGGAGT TTGTATCAAC AATGAAGTTG TTGAGCCAAG TGCTGAACAA 
ATTGCCAAAT ACAAAGAGCT TGTAGCCAAG ACATCGAACC TCGAGAACGT AAAGTTTGCT 
TGGCATAAGG AGACATCATC TGAATACCAA AGTAGAATGT TGGAGAAAAA GGAGCTTCAA 
AAGTGGGACT TTATTCATAT GATTCAAATG CTGTATTATG TAAAAGACAT CCCAGCTACC 
CTGAAATTCT TCCATAGTCT CTTAGGTACC AATGCTAAGA TGCTCATTAT TGTTGTGTCA 
GGAAGCAGTG GCTGGGACAA GCTGTGGAAA AAGTACGGAT CACGCTTTCC CCAGGATGAC 
CTCTGCCAGT ATATCACATC AGATGACCTC ACTCAGATGC TGGACAACCT AGGGCTTAAG 
TATGAGTGCT ATGACCTTTT GTCCACCATG GATATATCTG ACTGCTTTAT TGATGGTAAT 
GAAAATGGAG ACCTGCTTTG GGATTTTTTG ACTGAAACCT GCAACTTTAA TGCCACAGCA 
CCACCTGATC TCAGAGCAGA GCTTGGGAAA GATCTACAAG AGCCTGAATT TAGTGCTAAG 
AAAGAGGGGA AGGTTCTTTT TAATAATACT CTGAGTTTCA TAGTGATTGA GGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859437.1
CDS	817..1593
Translation	MAETLLSAWMTEIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA

Target ORF information:

RefSeq Version	XM_017003948.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003948.1

ORF Insert Sequence:

ATGGCTGAGA CACTGCTCTC AGCCTGGATG ACAGAGATTG GAGACACAAA ATCAGAAATT 
AAGATTCTAA GCATAGGCGG AGGTGCAGGT GAAATTGATC TTCAAATTCT CTCCAAAGTT 
CAGGCTCAAT ACCCAGGAGT TTGTATCAAC AATGAAGTTG TTGAGCCAAG TGCTGAACAA 
ATTGCCAAAT ACAAAGAGCT TGTAGCCAAG ACATCGAACC TCGAGAACGT AAAGTTTGCT 
TGGCATAAGG AGACATCATC TGAATACCAA AGTAGAATGT TGGAGAAAAA GGAGCTTCAA 
AAGTGGGACT TTATTCATAT GATTCAAATG CTGTATTATG TAAAAGACAT CCCAGCTACC 
CTGAAATTCT TCCATAGTCT CTTAGGTACC AATGCTAAGA TGCTCATTAT TGTTGTGTCA 
GGAAGCAGTG GCTGGGACAA GCTGTGGAAA AAGTACGGAT CACGCTTTCC CCAGGATGAC 
CTCTGCCAGT ATATCACATC AGATGACCTC ACTCAGATGC TGGACAACCT AGGGCTTAAG 
TATGAGTGCT ATGACCTTTT GTCCACCATG GATATATCTG ACTGCTTTAT TGATGGTAAT 
GAAAATGGAG ACCTGCTTTG GGATTTTTTG ACTGAAACCT GCAACTTTAA TGCCACAGCA 
CCACCTGATC TCAGAGCAGA GCTTGGGAAA GATCTACAAG AGCCTGAATT TAGTGCTAAG 
AAAGAGGGGA AGGTTCTTTT TAATAATACT CTGAGTTTCA TAGTGATTGA GGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( XM_011511064.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011509366.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58282
Clone ID Related Accession (Same CDS sequence)	XM_011511064.2
Accession Version	XM_011511064.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 501bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011511064.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGGAGA AAAAGGAGCT TCAAAAGTGG GACTTTATTC ATATGATTCA AATGCTGTAT 
TATGTAAAAG ACATCCCAGC TACCCTGAAA TTCTTCCATA GTCTCTTAGG TACCAATGCT 
AAGATGCTCA TTATTGTTGT GTCAGGAAGC AGTGGCTGGG ACAAGCTGTG GAAAAAGTAC 
GGATCACGCT TTCCCCAGGA TGACCTCTGC CAGTATATCA CATCAGATGA CCTCACTCAG 
ATGCTGGACA ACCTAGGGCT TAAGTATGAG TGCTATGACC TTTTGTCCAC CATGGATATA 
TCTGACTGCT TTATTGATGG TAATGAAAAT GGAGACCTGC TTTGGGATTT TTTGACTGAA 
ACCTGCAACT TTAATGCCAC AGCACCACCT GATCTCAGAG CAGAGCTTGG GAAAGATCTA 
CAAGAGCCTG AATTTAGTGC TAAGAAAGAG GGGAAGGTTC TTTTTAATAA TACTCTGAGT 
TTCATAGTGA TTGAGGCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011509366.1
CDS	396..896
Translation	MLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA

Target ORF information:

RefSeq Version	XM_011511064.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011511064.2

ORF Insert Sequence:

ATGTTGGAGA AAAAGGAGCT TCAAAAGTGG GACTTTATTC ATATGATTCA AATGCTGTAT 
TATGTAAAAG ACATCCCAGC TACCCTGAAA TTCTTCCATA GTCTCTTAGG TACCAATGCT 
AAGATGCTCA TTATTGTTGT GTCAGGAAGC AGTGGCTGGG ACAAGCTGTG GAAAAAGTAC 
GGATCACGCT TTCCCCAGGA TGACCTCTGC CAGTATATCA CATCAGATGA CCTCACTCAG 
ATGCTGGACA ACCTAGGGCT TAAGTATGAG TGCTATGACC TTTTGTCCAC CATGGATATA 
TCTGACTGCT TTATTGATGG TAATGAAAAT GGAGACCTGC TTTGGGATTT TTTGACTGAA 
ACCTGCAACT TTAATGCCAC AGCACCACCT GATCTCAGAG CAGAGCTTGG GAAAGATCTA 
CAAGAGCCTG AATTTAGTGC TAAGAAAGAG GGGAAGGTTC TTTTTAATAA TACTCTGAGT 
TTCATAGTGA TTGAGGCATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( XM_017003949.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859438.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu89350
Clone ID Related Accession (Same CDS sequence)	XM_017003949.1 , XM_017003949.2
Accession Version	XM_017003949.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAG TAAATGAAAA TCTTCTGATT TCTAATTTTA CAAGTGACCA TGATCTGCCC 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859438.1
CDS	88..573
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQVNENLLISNFTSDHDLPK

Target ORF information:

RefSeq Version	XM_017003949.1
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003949.1

ORF Insert Sequence:

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAG TAAATGAAAA TCTTCTGATT TCTAATTTTA CAAGTGACCA TGATCTGCCC 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( XM_017003949.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859438.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu89350
Clone ID Related Accession (Same CDS sequence)	XM_017003949.1 , XM_017003949.2
Accession Version	XM_017003949.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575475200000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017003949.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAG TAAATGAAAA TCTTCTGATT TCTAATTTTA CAAGTGACCA TGATCTGCCC 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859438.1
CDS	87..572
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQVNENLLISNFTSDHDLPK

Target ORF information:

RefSeq Version	XM_017003949.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003949.2

ORF Insert Sequence:

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAG TAAATGAAAA TCTTCTGATT TCTAATTTTA CAAGTGACCA TGATCTGCCC 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( NM_001024074.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001019245.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11921
Clone ID Related Accession (Same CDS sequence)	NM_001024074.2 , NM_001024074.3
Accession Version	NM_001024074.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 156bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1545408000000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093674.2 and BC005907.1. On Jan 6, 2010 this sequence version replaced NM_001024074.1. Transcript Variant: This variant (2) includes an alternate exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. This transcript is supported by multiple mRNAs and ESTs, but the predicted ORF has not yet been experimentally confirmed. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC005907.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGATA CCAGAATTGC TGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019245.1
CDS	255..410
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRYQNCC

Target ORF information:

RefSeq Version	NM_001024074.2
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024074.2

ORF Insert Sequence:

1
61
121

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGATA CCAGAATTGC TGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( NM_001024074.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001019245.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11921
Clone ID Related Accession (Same CDS sequence)	NM_001024074.2 , NM_001024074.3
Accession Version	NM_001024074.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 156bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571932800000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093674.2. On May 31, 2019 this sequence version replaced NM_001024074.2. Transcript Variant: This variant (2) includes an alternate exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. This transcript is supported by multiple mRNAs and ESTs, but the predicted ORF has not yet been experimentally confirmed. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC005907.1, DRR138519.399009.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGATA CCAGAATTGC TGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019245.1
CDS	20..175
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRYQNCC

Target ORF information:

RefSeq Version	NM_001024074.3
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024074.3

ORF Insert Sequence:

1
61
121

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGATA CCAGAATTGC TGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNMT ( NM_006895.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_008826.1 Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18910
Clone ID Related Accession (Same CDS sequence)	NM_006895.3 , NM_006895.2
Accession Version	NM_006895.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573833600000
Organism	Homo sapiens(human)
Product	histamine N-methyltransferase isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF523358.1, AF523360.1, AC093674.2 and AA935821.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_006895.2. Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.114944.1, SRR1660805.150107.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000280097.5/ ENSP00000280097.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAA TGCTGTATTA TGTAAAAGAC ATCCCAGCTA CCCTGAAATT CTTCCATAGT 
CTCTTAGGTA CCAATGCTAA GATGCTCATT ATTGTTGTGT CAGGAAGCAG TGGCTGGGAC 
AAGCTGTGGA AAAAGTACGG ATCACGCTTT CCCCAGGATG ACCTCTGCCA GTATATCACA 
TCAGATGACC TCACTCAGAT GCTGGACAAC CTAGGGCTTA AGTATGAGTG CTATGACCTT 
TTGTCCACCA TGGATATATC TGACTGCTTT ATTGATGGTA ATGAAAATGG AGACCTGCTT 
TGGGATTTTT TGACTGAAAC CTGCAACTTT AATGCCACAG CACCACCTGA TCTCAGAGCA 
GAGCTTGGGA AAGATCTACA AGAGCCTGAA TTTAGTGCTA AGAAAGAGGG GAAGGTTCTT 
TTTAATAATA CTCTGAGTTT CATAGTGATT GAGGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008826.1
CDS	20..898
Translation	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA

Target ORF information:

RefSeq Version	NM_006895.3
Organism	Homo sapiens(human)
Definition	Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006895.3

ORF Insert Sequence:

ATGGCATCTT CCATGAGGAG CTTGTTTTCT GACCACGGGA AATATGTTGA ATCTTTCCGG 
AGGTTTCTCA ACCATTCCAC GGAACACCAG TGCATGCAGG AATTCATGGA CAAGAAGCTG 
CCAGGCATAA TAGGAAGGAT TGGAGACACA AAATCAGAAA TTAAGATTCT AAGCATAGGC 
GGAGGTGCAG GTGAAATTGA TCTTCAAATT CTCTCCAAAG TTCAGGCTCA ATACCCAGGA 
GTTTGTATCA ACAATGAAGT TGTTGAGCCA AGTGCTGAAC AAATTGCCAA ATACAAAGAG 
CTTGTAGCCA AGACATCGAA CCTCGAGAAC GTAAAGTTTG CTTGGCATAA GGAGACATCA 
TCTGAATACC AAAGTAGAAT GTTGGAGAAA AAGGAGCTTC AAAAGTGGGA CTTTATTCAT 
ATGATTCAAA TGCTGTATTA TGTAAAAGAC ATCCCAGCTA CCCTGAAATT CTTCCATAGT 
CTCTTAGGTA CCAATGCTAA GATGCTCATT ATTGTTGTGT CAGGAAGCAG TGGCTGGGAC 
AAGCTGTGGA AAAAGTACGG ATCACGCTTT CCCCAGGATG ACCTCTGCCA GTATATCACA 
TCAGATGACC TCACTCAGAT GCTGGACAAC CTAGGGCTTA AGTATGAGTG CTATGACCTT 
TTGTCCACCA TGGATATATC TGACTGCTTT ATTGATGGTA ATGAAAATGG AGACCTGCTT 
TGGGATTTTT TGACTGAAAC CTGCAACTTT AATGCCACAG CACCACCTGA TCTCAGAGCA 
GAGCTTGGGA AAGATCTACA AGAGCCTGAA TTTAGTGCTA AGAAAGAGGG GAAGGTTCTT 
TTTAATAATA CTCTGAGTTT CATAGTGATT GAGGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Determining the Effect of the HNMT, STK39, and NMD3 Polymorphisms on the Incidence of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Multiple System Atrophy in Chinese Populations.
Journal of molecular neuroscience : MN64(4)574-580(2018 Apr)
Chen Y,Cao B,Ou R,Wei Q,Chen X,Zhao B,Wu Y,Song W,Shang HF

MicroRNA-223 is involved in the pathogenesis of atopic dermatitis by affecting histamine-N-methyltransferase.
Cellular and molecular biology (Noisy-le-Grand, France)64(3)103-107(2018 Feb)
Jia HZ,Liu SL,Zou YF,Chen XF,Yu L,Wan J,Zhang HY,Chen Q,Xiong Y,Yu B,Zhang W

Histaminergic gene polymorphisms associated with sedation in clozapine-treated patients.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology27(5)442-449(2017 05)
Solismaa A,Kampman O,Lyytikäinen LP,Seppälä N,Viikki M,Mononen N,Lehtimäki T,Leinonen E

Thr105Ile (rs11558538) polymorphism in the histamine-1-methyl-transferase (HNMT) gene and risk for restless legs syndrome.
Journal of neural transmission (Vienna, Austria : 1996)124(3)285-291(2017 03)
Jiménez-Jiménez FJ,García-Martín E,Alonso-Navarro H,Martínez C,Zurdo M,Turpín-Fenoll L,Millán-Pascual J,Adeva-Bartolomé T,Cubo E,Navacerrada F,Rojo-Sebastián A,Rubio L,Ortega-Cubero S,Pastor P,Calleja M,Plaza-Nieto JF,Pilo-de-la-Fuente B,Arroyo-Solera M,García-Albea E,Agúndez JA

Leucine 208 in human histamine N-methyltransferase emerges as a hotspot for protein stability rationalizing the role of the L208P variant in intellectual disability.
Biochimica et biophysica acta. Molecular basis of disease1863(1)188-199(2017 01)
Tongsook C,Niederhauser J,Kronegger E,Straganz G,Macheroux P

Gene Symbol	HNMT
Entrez Gene ID	3176
Full Name	histamine N-methyltransferase
Synonyms	HMT,HNMT-S1,HNMT-S2,MRT51
General protein information	Preferred Names histamine N-methyltransferase Names histamine N-methyltransferase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q22.1
Summary	In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	605238
Disorder Html:	{Asthma, susceptibility to}, 600807 (3); Mental retardation, autosomal recessive 51, 616739 (3)

Homo sapiens (human)	HNMT	NP_008826.1
Pan troglodytes (chimpanzee)	HNMT	XP_001156140.1
Canis lupus familiaris (dog)	HNMT	XP_533340.1
Rattus norvegicus (Norway rat)	Hnmt	NP_112306.1
Gallus gallus (chicken)	HNMT	NP_001264802.1
Macaca mulatta (Rhesus monkey)	HNMT	XP_001094746.1
Bos taurus (cattle)	HNMT	NP_001030511.1
Xenopus tropicalis (tropical clawed frog)	hnmt	NP_001072355.1
Mus musculus (house mouse)	Hnmt	NP_536710.1
Danio rerio (zebrafish)	hnmt	NP_001003636.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

HNMT cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM