Avil cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Avil
Entrez Gene ID	79253
Full Name	advillin
General protein information	Preferred Names advillin Names advillin peripheral nervous system villin-like protein pervin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_024401.2	NP_077377.2	advillin

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	AVIL	XP_509177.2
Bos taurus (cattle)	AVIL	NP_001179458.1
Arabidopsis thaliana (thale cress)	VLN2	NP_565958.1
Xenopus tropicalis (tropical clawed frog)	avil	XP_002933749.1
Mus musculus (house mouse)	Avil	NP_033765.2
Danio rerio (zebrafish)	avil	NP_001035455.1
Arabidopsis thaliana (thale cress)	VLN3	NP_567048.1
Rattus norvegicus (Norway rat)	Avil	NP_077377.2
Oryza sativa (rice)	Os03g0356700	NP_001050140.1
Canis lupus familiaris (dog)	AVIL	XP_005625616.1
Homo sapiens (human)	AVIL	NP_006567.3
Macaca mulatta (Rhesus monkey)	AVIL	XP_001101627.2

Gene Ontology
Bibliography

Related articles in PubMed

Functional genomic screen for modulators of ciliogenesis and cilium length.
Kim J, Lee JE, Heynen-Genel S, Suyama E, Ono K, Lee K, Ideker T, Aza-Blanc P, Gleeson JG
Nature464(7291)1048-51(2010 Apr)

Type F scavenger receptor SREC-I interacts with advillin, a member of the gelsolin/villin family, and induces neurite-like outgrowth.
Shibata M, Ishii J, Koizumi H, Shibata N, Dohmae N, Takio K, Adachi H, Tsujimoto M, Arai H
The Journal of biological chemistry279(38)40084-90(2004 Sep)

A peripheral nervous system actin-binding protein regulates neurite outgrowth.
Ravenall SJ, Gavazzi I, Wood JN, Akopian AN
The European journal of neuroscience15(2)281-90(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Avil gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Avil cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07051	NM_024401.2 Latest version!	Rattus norvegicus advillin (Avil), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Avil ( NM_024401.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_077377.2 Rattus norvegicus advillin (Avil), mRNA.

Price & Availability↑

CloneID	ORa07051
Clone ID Related Accession (Same CDS sequence)	NM_024401.2
Accession Version	NM_024401.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2460bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571587200000
Organism	Rattus norvegicus(Norway rat)
Product	advillin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAHX01049862.1. On Jul 28, 2011 this sequence version replaced NM_024401.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF099929.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCTCTGA GCAGTGCCTT CAGGACTGTG ACCAATGACC CCGGGATTAT CACGTGGAGA 
ATTGAGAAAA TGGAGCTGGT GCTGGTGCCC CTGAGTGCTC ATGGCAACTT CTATGAGGGA 
GACTGCTACA TCATCCTCTC GACCCGGAGA GTGGGCAGCC TTCTCTCCCA AAACATCCAC 
TTTTGGATCG GGAAGGACTC CTCCCAAGAT GAGCAGAGCT GTGCAGCCAT CTATACCACA 
CAGCTGGATG ACTACCTGGG AGGCAGCCCC GTGCAGCACC GTGAGGTCCA GTACCATGAG 
TCTGACACCT TCCGTGGCTA CTTCAAGCGG GGCATCATCT ATAAAAAGGG GGGTGTGGCC 
TCTGGGATGA AGCATGTGGA GACCAACACC TATGATGTGA AGAGGCTGTT ACATGTGAAG 
GGGAAAAGAA ACATCAGAGC CACTGAGGTG GAAATGAGCT GGGACAGTTT TAACCAAGGT 
GATGTCTTCT TGCTGGACCT CGGGATGGTC ATCATCCAGT GGAATGGCCC GGAGAGCAAC 
AGTGGGGAAC GCCTCAAGGC TATGCTTCTA GCAAAGGACA TTCGGGACAG GGAGCGAGGG 
GGCCGAGCTG AAATCGGGGT GATTGAGGGA GACAAAGAGG CAGCCAGCCC AGAACTGATG 
ACGGTTCTCC AGAATACCCT TGGCCGACGC TCCATTATCA AGCCCGCAGT TCCTGATGAG 
GTCACCGATC AGCAGCAGAA GTCAACCATC ATGTTGTATC ATGTCTCCGA CACAACTGGG 
CAGCTGTCGG TCACAGAAGT GGCAACAAGG CCCCTGGTCC AGGAGCTACT GAACCATGAT 
GACTGCTATA TCCTGGACCA AAGTGGCACC AAGATCTACG TATGGAAAGG CAAAGGAGCC 
ACCAAGGTGG AGAAACAGGC GGCCATGTCC AAAGCCCTGG ATTTCATCAA GATGAAGGGT 
TATCCCAGCA GCACCAACGT AGAGACCGTC AACGATGGCG CAGAGTCGGC CATGTTCAAA 
CAGTTGTTCC AGAAATGGTC GGTGAAGGAC CAGACCACTG GCTTGGGGAA AACATTCAGC 
ATTGGTAAAA TTGCTAAAAT CTTCCAGGAC AAGTTCGACG TGACTCTGCT ACACACTAAG 
CCAGAAGTGG CTGCTCAGGA AAGAATGGTG GACGACGGCA ACGGCAAGGT TGAGGTCTGG 
AGAATTGAGA ACCTGGAGCT GGTCCCTGTG GAATACCAGT GGCATGGCTT CTTCTACGGG 
GGAGACTGCT ATCTGGTTCT CTACACGTAT GATGTGAACG GGAAACCCTG TTACATCTTG 
TATATCTGGC AGGGACGCCA CGCTTCCCAG GATGAGCTGG CAGCCTCGGC CTACCAGGCG 
GTGGAGGTGG ATCAGCAGTT TGGTGGAGCC CCGGTGCAAG TCCGGGTTAG CATGGGGAAA 
GAGCCACGCC ACTTCATGGC CATCTTCAAA GGGAAGCTGG TTATCTATGA GGGCGGGACT 
TCCAGGAAGG GAAATGTGGA GCCTGACCCT CCAGTAAGAC TCTTCCAGAT CCACGGGAAC 
GACAAATCCA ATACCAAAGC AGTGGAAGTC TCGGCCTCCG CTTCCTCCCT CAACTCTAAT 
GATGTCTTTC TGCTTTGGAC TCAGGCGGAG CACTACCTGT GGTATGGCAA GGGGTCAAGT 
GGGGACGAAC GGGCGATGGC TAAGGAGCTG GCAGAGCTTC TCTGTGATGG TGACGCAGAC 
ACTGTAGCTG AGGGCCAGGA GCCACCTGAG TTCTGGGACC TTCTGGGAGG AAAAGCCCCC 
TACGCTAACG ACAAAAGGCT GCAGCAGGAA ACCCTGGACA TCCAGGTCCG GCTTTTTGAA 
TGTTCTAATA AGACCGGCCG GTTCCTTGTT ACTGAGGTCA CGGACTTCAC CCAGGATGAC 
CTGAGCCCAG GTGATGTGAT GCTCCTGGAC ACCTGGGACC AGGTGTTCCT GTGGATAGGA 
GCGGAGGCCA ATGCCACAGA GAAGGAGGGG GCCCTCTCGA CTGCTCAGGA GTACCTGGTA 
ACACACCCCA GTGGCCGAGA CCCCGACACA CCGATCCTGA TCATCAAACA GGGCTTTGAG 
CCCCCCACTT TCACAGGCTG GTTCCTGGCA TGGGACCCTC ACATTTGGAG TGAAGGAAAA 
TCATATGAGC AGTTAAAGAA CGAGCTGGGA GATGCCACTG CTATCGTGCG AATCACCACG 
GACATGAAGA ACGCAACCCT CTCCCTGAAT TCTAGTGAAA GTGGGCCAAA GTACTACCCT 
GTGGAGGTTC TGCTGAAAAG TCAGGACCAG GAGCTGCCTG AGGATGTGGA CCCCACCAAA 
AAGGAGAATT ACCTCTCGGA ACGAGATTTT GTCTCTGTGT TTGGCATCAC CAGAGGGCAG 
TTTGTCTCTC TGCCTGGCTG GAAACAGCTC CAGCTGAAGA AAGAAGCAGG CCTTTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077377.2
CDS	114..2573
Translation	MSLSSAFRTVTNDPGIITWRIEKMELVLVPLSAHGNFYEGDCYIILSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKRGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNQGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMTVLQNTLGRRSIIKPAVPDEVTDQQQKSTIMLYHVSDTTGQLSVTEVATRPLVQELLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKTFSIGKIAKIFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPCYILYIWQGRHASQDELAASAYQAVEVDQQFGGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNVEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLWTQAEHYLWYGKGSSGDERAMAKELAELLCDGDADTVAEGQEPPEFWDLLGGKAPYANDKRLQQETLDIQVRLFECSNKTGRFLVTEVTDFTQDDLSPGDVMLLDTWDQVFLWIGAEANATEKEGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITTDMKNATLSLNSSESGPKYYPVEVLLKSQDQELPEDVDPTKKENYLSERDFVSVFGITRGQFVSLPGWKQLQLKKEAGLF

Target ORF information:

RefSeq Version	NM_024401.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus advillin (Avil), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024401.2

ORF Insert Sequence:

ATGTCTCTGA GCAGTGCCTT CAGGACTGTG ACCAATGACC CCGGGATTAT CACGTGGAGA 
ATTGAGAAAA TGGAGCTGGT GCTGGTGCCC CTGAGTGCTC ATGGCAACTT CTATGAGGGA 
GACTGCTACA TCATCCTCTC GACCCGGAGA GTGGGCAGCC TTCTCTCCCA AAACATCCAC 
TTTTGGATCG GGAAGGACTC CTCCCAAGAT GAGCAGAGCT GTGCAGCCAT CTATACCACA 
CAGCTGGATG ACTACCTGGG AGGCAGCCCC GTGCAGCACC GTGAGGTCCA GTACCATGAG 
TCTGACACCT TCCGTGGCTA CTTCAAGCGG GGCATCATCT ATAAAAAGGG GGGTGTGGCC 
TCTGGGATGA AGCATGTGGA GACCAACACC TATGATGTGA AGAGGCTGTT ACATGTGAAG 
GGGAAAAGAA ACATCAGAGC CACTGAGGTG GAAATGAGCT GGGACAGTTT TAACCAAGGT 
GATGTCTTCT TGCTGGACCT CGGGATGGTC ATCATCCAGT GGAATGGCCC GGAGAGCAAC 
AGTGGGGAAC GCCTCAAGGC TATGCTTCTA GCAAAGGACA TTCGGGACAG GGAGCGAGGG 
GGCCGAGCTG AAATCGGGGT GATTGAGGGA GACAAAGAGG CAGCCAGCCC AGAACTGATG 
ACGGTTCTCC AGAATACCCT TGGCCGACGC TCCATTATCA AGCCCGCAGT TCCTGATGAG 
GTCACCGATC AGCAGCAGAA GTCAACCATC ATGTTGTATC ATGTCTCCGA CACAACTGGG 
CAGCTGTCGG TCACAGAAGT GGCAACAAGG CCCCTGGTCC AGGAGCTACT GAACCATGAT 
GACTGCTATA TCCTGGACCA AAGTGGCACC AAGATCTACG TATGGAAAGG CAAAGGAGCC 
ACCAAGGTGG AGAAACAGGC GGCCATGTCC AAAGCCCTGG ATTTCATCAA GATGAAGGGT 
TATCCCAGCA GCACCAACGT AGAGACCGTC AACGATGGCG CAGAGTCGGC CATGTTCAAA 
CAGTTGTTCC AGAAATGGTC GGTGAAGGAC CAGACCACTG GCTTGGGGAA AACATTCAGC 
ATTGGTAAAA TTGCTAAAAT CTTCCAGGAC AAGTTCGACG TGACTCTGCT ACACACTAAG 
CCAGAAGTGG CTGCTCAGGA AAGAATGGTG GACGACGGCA ACGGCAAGGT TGAGGTCTGG 
AGAATTGAGA ACCTGGAGCT GGTCCCTGTG GAATACCAGT GGCATGGCTT CTTCTACGGG 
GGAGACTGCT ATCTGGTTCT CTACACGTAT GATGTGAACG GGAAACCCTG TTACATCTTG 
TATATCTGGC AGGGACGCCA CGCTTCCCAG GATGAGCTGG CAGCCTCGGC CTACCAGGCG 
GTGGAGGTGG ATCAGCAGTT TGGTGGAGCC CCGGTGCAAG TCCGGGTTAG CATGGGGAAA 
GAGCCACGCC ACTTCATGGC CATCTTCAAA GGGAAGCTGG TTATCTATGA GGGCGGGACT 
TCCAGGAAGG GAAATGTGGA GCCTGACCCT CCAGTAAGAC TCTTCCAGAT CCACGGGAAC 
GACAAATCCA ATACCAAAGC AGTGGAAGTC TCGGCCTCCG CTTCCTCCCT CAACTCTAAT 
GATGTCTTTC TGCTTTGGAC TCAGGCGGAG CACTACCTGT GGTATGGCAA GGGGTCAAGT 
GGGGACGAAC GGGCGATGGC TAAGGAGCTG GCAGAGCTTC TCTGTGATGG TGACGCAGAC 
ACTGTAGCTG AGGGCCAGGA GCCACCTGAG TTCTGGGACC TTCTGGGAGG AAAAGCCCCC 
TACGCTAACG ACAAAAGGCT GCAGCAGGAA ACCCTGGACA TCCAGGTCCG GCTTTTTGAA 
TGTTCTAATA AGACCGGCCG GTTCCTTGTT ACTGAGGTCA CGGACTTCAC CCAGGATGAC 
CTGAGCCCAG GTGATGTGAT GCTCCTGGAC ACCTGGGACC AGGTGTTCCT GTGGATAGGA 
GCGGAGGCCA ATGCCACAGA GAAGGAGGGG GCCCTCTCGA CTGCTCAGGA GTACCTGGTA 
ACACACCCCA GTGGCCGAGA CCCCGACACA CCGATCCTGA TCATCAAACA GGGCTTTGAG 
CCCCCCACTT TCACAGGCTG GTTCCTGGCA TGGGACCCTC ACATTTGGAG TGAAGGAAAA 
TCATATGAGC AGTTAAAGAA CGAGCTGGGA GATGCCACTG CTATCGTGCG AATCACCACG 
GACATGAAGA ACGCAACCCT CTCCCTGAAT TCTAGTGAAA GTGGGCCAAA GTACTACCCT 
GTGGAGGTTC TGCTGAAAAG TCAGGACCAG GAGCTGCCTG AGGATGTGGA CCCCACCAAA 
AAGGAGAATT ACCTCTCGGA ACGAGATTTT GTCTCTGTGT TTGGCATCAC CAGAGGGCAG 
TTTGTCTCTC TGCCTGGCTG GAAACAGCTC CAGCTGAAGA AAGAAGCAGG CCTTTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional genomic screen for modulators of ciliogenesis and cilium length.
Nature464(7291)1048-51(2010 Apr)
Kim J,Lee JE,Heynen-Genel S,Suyama E,Ono K,Lee K,Ideker T,Aza-Blanc P,Gleeson JG

Type F scavenger receptor SREC-I interacts with advillin, a member of the gelsolin/villin family, and induces neurite-like outgrowth.
The Journal of biological chemistry279(38)40084-90(2004 Sep)
Shibata M,Ishii J,Koizumi H,Shibata N,Dohmae N,Takio K,Adachi H,Tsujimoto M,Arai H

A peripheral nervous system actin-binding protein regulates neurite outgrowth.
The European journal of neuroscience15(2)281-90(2002 Jan)
Ravenall SJ,Gavazzi I,Wood JN,Akopian AN

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Avil cDNA ORF clone, Rattus norvegicus(Norway rat)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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