Duox2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Duox2
Entrez Gene ID	79107
Full Name	dual oxidase 2
Synonyms	Thox2
General protein information	Preferred Names dual oxidase 2 Names dual oxidase 2 NADH/NADPH thyroid oxidase THOX2 large NOX 2 long NOX 2 thyroid oxidase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q35
Summary	a thyroid NADPH oxidase flavoprotein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_024141.1	NP_077055.1	dual oxidase 2 precursor
XM_006234862.3	XP_006234924.1	dual oxidase 2 isoform X1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LOC713906	XP_001103398.2
Canis lupus familiaris (dog)	DUOX2	XP_005638424.1
Rattus norvegicus (Norway rat)	Duox2	NP_077055.1
Bos taurus (cattle)	DUOX2	XP_002690988.2
Anopheles gambiae (African malaria mosquito)	DUOX	XP_319115.4
Homo sapiens (human)	DUOX2	NP_054799.4
Drosophila melanogaster (fruit fly)	Duox	NP_001259968.1
Caenorhabditis elegans (roundworm)	bli-3	NP_490686.3
Pan troglodytes (chimpanzee)	DUOX2	XP_510367.3
Arabidopsis thaliana (thale cress)	RBOHB	NP_973799.1
Mus musculus (house mouse)	Duox2	NP_808278.2
Caenorhabditis elegans (roundworm)	duox-2	NP_490684.1
Xenopus tropicalis (tropical clawed frog)	duox2	XP_002937935.1

Gene Ontology
Bibliography

Related articles in PubMed

When an Intramolecular Disulfide Bridge Governs the Interaction of DUOX2 with Its Partner DUOXA2.
Carré A, Louzada RA, Fortunato RS, Ameziane-El-Hassani R, Morand S, Ogryzko V, de Carvalho DP, Grasberger H, Leto TL, Dupuy C
Antioxidants & redox signaling23(9)724-33(2015 Sep)

New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells.
Fernández LP, López-Márquez A, Martínez AM, Gómez-López G, Santisteban P
PloS one8(5)e62849(2013)

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.
Hoste C, Dumont JE, Miot F, De Deken X
Experimental cell research318(18)2353-64(2012 Nov)

Identification and functional analysis of novel dual oxidase 2 (DUOX2) mutations in children with congenital or subclinical hypothyroidism.
De Marco G, Agretti P, Montanelli L, Di Cosmo C, Bagattini B, De Servi M, Ferrarini E, Dimida A, Freitas Ferreira AC, Molinaro A, Ceccarelli C, Brozzi F, Pinchera A, Vitti P, Tonacchera M
The Journal of clinical endocrinology and metabolism96(8)E1335-9(2011 Aug)

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.
Luxen S, Noack D, Frausto M, Davanture S, Torbett BE, Knaus UG
Journal of cell science122(Pt 8)1238-47(2009 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Duox2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Duox2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06824	NM_024141.1 Latest version!	Rattus norvegicus dual oxidase 2 (Duox2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
ORa26289	XM_006234862.3 Latest version!	Rattus norvegicus dual oxidase 2 (Duox2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Duox2 ( NM_024141.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_077055.1 Rattus norvegicus dual oxidase 2 (Duox2), mRNA.

Price & Availability↑

CloneID	ORa06824
Clone ID Related Accession (Same CDS sequence)	NM_024141.1
Accession Version	NM_024141.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	dual oxidase 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF237962.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF237962.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCTTCCAA CAAGTCTCAA GACATTGGTG CTCCTGGGCG CTCTGTTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA TGCACCCTCA CTGCCCCGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTCAAGTA CCACCAGCGC GGTGCAGCTG GCTCGCAGCT GCGTCGCCTA 
GTACCTGCTA ATTACGCTGA CGGTGTTTAT CAGGCTCTGC AGGAGCCGCT ACTCCCCAAC 
GCTCGCCTGC TAAGCGACGC TGTCAGTAAG GGCAAAGCAG GGCTGCCCTC GGCGCACAAC 
CGCACAGTGC TTGGGCTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCAGTGTTT 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAGA GGAGCCGCTG GGACCGCAGC 
ACTGGACAGA GCCCTAGCAA CCCCCGAGAC CTGACCAACC AGGTGACTGG CTGGTTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGCGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGCCC TGACCCTGCT TTCCCGAGGA ACTCCCAGAA CTCTCTGCTC 
ATGTGGATGG CACCAGACCC CGCCACGGGG CAGGGCGGGC CACAGGGGCT GTATGCCTTC 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCAC TGGGCTTGTT GTGGTTTCGA 
TACCACAACC TGTGTGCCAA GAGGCTGGCG CAGGAGCACC CACACTGGGG GGATGAGGAG 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACTTACC AGAACATTGC TCTATACCAA 
TGGTTGCCCA GCTTCCTGCA GAAAACACCC CCAGAGTATT CCGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCAGA GTTCGTGGCG GCCTCAGAGC AGTTCCTCTC TACCATGGTG 
CCCCCGGGGG TCTATATGAG AAACTCCAGC TGTCACTTCC GGGAATTCCC AAAGGAAGGT 
TCCAGCAGCT CTCCAGCTCT CAGGGTCTGC AACAACTACT GGATTCGGGA GAACCCCAGT 
CTGAAGACTG CTCAGGACGT GGACCAGCTG CTGCTGGGAA TGGCTTCCCA GATTTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGATCTG AGAGATTACT GGCCTGGCCC AGACAGATAC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGAGTGGCC GAGATATGGG GCTGCCCAGT 
TATAGCCAGG CTCTGCAGGC CTTAGGACTG GAGCCTCCCA AGAATTGGAG TGCTCTCAAC 
CCCAAAGTGG ATCCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CGGTTGGAAC TATTCCTGGG AGGGCTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTAAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ACGGGCTGTT CTCCAAGGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAGCC CAATGTTTTC 
TTCTGGCAAG AAGGTGCACC CTGCCCACAG CCTCAGCAAC TCACAACTGA AGGCTTGCCC 
CAGTGTGTGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACCCTCCTGG CTGTCTGCTG CTTTCCAGTA GTGAGTCTGA TTATTGCTTG GGTGGTGGCT 
CGTTTCCGGA ACCGAGAACG CAAGATGCTA CTAAAGAAAG GCAAGGAGAG TCTAAAGAAA 
CAGACAGCCA GTGATGGAGT ACCAGCGATG GAGTGGCCAG GCCCCAAGGA GAGCAGCTAC 
CCAGTCACTG TCCAGCTGCT TCCAGACAGG AGTCTGAAGG TCCTTGACAA AAGGCTCACT 
GTGCTCCGTA CCATCCAACT GCAGCCCACA CAGCAGGTCA ACCTCATCCT GTCCAGCAGC 
CATGGACGCC GCACCCTGTT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGA TGCCTTCGTG CAGCTGTTGC AAGACCTCTG CGTCTGCTCC 
ACTCCCGGCC TCCGCATAGC TGAGATGGAT GAGAAGGAGC TACTGAGAAA GGCTGTGACC 
AAGCAGCAGC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAATC AGGCCGACGC AGGGACTCTG CCTCTGGACT CATCCCAGCA AGTACGAGAG 
GCTCTGACCT GTGAACTGAG CAGAGCGGAG TTTGCGGACT CCCTGGGCCT CAAGCCCCAG 
GATATGTTTG TGGAGTCCAT GTTTTCTCTG GCCGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTT TTCATGAAAG GTTCCCCACA GGACAAGTCT 
CGCCTAATGT TTACCATGTA TGACCTGGAT GGAAATGGCT TTCTCTCCAA GGAGGAATTC 
TTCACCATGA TGCGGTCCTT CATCGAGATC TCCAACAACT GCCTGTCCAA GGACCAGCTG 
GCTGAGGTGG TGGAATCCAT GTTCCGGGAG TCGGGCTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCATTTCAT GCTGCGCGAC CACGACAGCG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGGGCTGG AGGCACCGGG GACATCTTTA AGCAAAGCAA TGCCTGTCGA 
GTCTCATTCC TCACCCGGAC TCCTGGGAAC AGGGTAATGG CTCCCTCTCC CCGGCTGTAC 
ACGGAAGCAC TGCAGGAGAA AATGCAGAGG GGCTTCCTAG CCCAGAAGCT CAAGCAGTTC 
AAGCGGTTTG TGGAAAACTA CCGGCGCCAC ATCGTGTGTG TTACAATCTT CTCAGCCATC 
TGCGCAGGCC TGTTTGCAGA CCGTGCCTAC TACTATGGCT TTGCCTCGCC ACCCACGGAC 
ATTGAAGAAA CCACCTATGT GGGCATCATC CTGTCCCGGG GCACAGCAGC CAGCATCTCC 
TTCATGTTCT CCTACATCCT GCTCACCATG TGCCGCAACC TCATCACCTT CCTGCGGGAG 
ACCTTCCTCA ACCGCTACAT TCCCTTTGAT GCCGCTGTGG ACTTCCACCG CTGGATCGCC 
ATGGCTGCGG TTGTCCTAGC TGTTGTGCAC AGTCTTGGAC ATGCAGTCAA CGTGTACATC 
TTCTCAGTCA GTCCCCTCAG CCTGATGACC TGCGTCTTCC CTAGTGTCTT TGTGAATGAT 
GGGTCCAAGC TTCCCCCAAA GTACTACTGG TGGTTCTTCG AGACAGTTCC AGGTATGACA 
GGAGTACTCC TGCTCCTGGT CCTGGCTATC ATGTATGTGT TTGCCTCCCA CCACTTCCGC 
CGCCACAGTT TCCGGGGCTT CTGGTTGACC CACCACCTCT ATGTTGTGCT TTATGCCCTG 
ATCATCATCC ATGGCAGCTA TGCCCTCATC CAATTACCCA GCTTCCACAT CTACTTCCTG 
GTCCCCGCCA TTATCTATGT GGGGGACAAG CTGGTGAGCC TGAGCCGGAA GAAGGTGGAG 
ATCAGTGTGG TGAAGGTTGA GCTGCTGCCT TCAGGGGTGA CCTATCTGCA GTTCCAGCGG 
CCCAAGACTT TTGAGTACAA ATCCGGGCAG TGGGTGCGGA TCGCTTGCTT GAGTCTGGGA 
ACCAATGAGT ACCACCCCTT CACGCTGACC TCCGCACCCC ATGAGGACAC ACTCAGCCTG 
CACATCCGGG CTGTGGGACC TTGGACTACT CGCCTCAGGG AGATCTACTC ACCTCCAGTG 
GGTGGCACCA GCGCCAGATA CCCAAAGCTG TACCTCGATG GACCATTCGG AGAGGGCCAC 
CAGGAATGGC ACAAGTTTGA GGTGTCGGTG CTGGTAGGAG GGGGCATTGG GGTCACCCCC 
TTTGCCTCCA TCCTCAAAGA CCTGGTCTTC AAATCGTCCA TGGGTACCCA GATGCTATGT 
AAGAAGATCT ACTTCATCTG GGTGACAAGG ACTCAGCGGC AGTTTGAGTG GCTGGCTGAC 
ATCATCCGGG AAGTGGAGGA GAATGGCAGC CGGGACCTGG TGTCTGTGCA CATCTATATC 
ACTCAGCTGG CTGAGAAGTT TGACCTCAGG ACGACCATGC TGTACATCTG TGAGAGGCAC 
TTCCAGAAGG TGCTGAACAG GAGTCTGTTC ACGGGCCTGC GCTCTGTCAC CCACTTTGGT 
CGCCCTCCCT TTGAGCTCTT CTTAGACTCT CTGCAGGAGG TTCATCCACA GGTACATAAG 
ATTGGTGTGT TCAGCTGTGG TCCTCCAGGG ATGACCAAGA ATGTGGAGAA GGCCTGTCAG 
CTCATCAACA GGCAGGACCG GGCCCACTTT GTGCATCATT ATGAGAACTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_077055.1
CDS	1..4554
Translation	MLPTSLKTLVLLGALLTGPLGPAGGQDAPSLPREVQRYDGWFNNLKYHQRGAAGSQLRRLVPANYADGVYQALQEPLLPNARLLSDAVSKGKAGLPSAHNRTVLGLFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDRSTGQSPSNPRDLTNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQNSLLMWMAPDPATGQGGPQGLYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNIALYQWLPSFLQKTPPEYSGYRPFMDPSISPEFVAASEQFLSTMVPPGVYMRNSSCHFREFPKEGSSSSPALRVCNNYWIRENPSLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPDRYSRTDYVASSIQSGRDMGLPSYSQALQALGLEPPKNWSALNPKVDPQVLEATAALYNQDLSRLELFLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPQQLTTEGLPQCVPVTVIDYFEGSGAGYGVTLLAVCCFPVVSLIIAWVVARFRNRERKMLLKKGKESLKKQTASDGVPAMEWPGPKESSYPVTVQLLPDRSLKVLDKRLTVLRTIQLQPTQQVNLILSSSHGRRTLLLKIPKEYDLVLMFNSEEDRDAFVQLLQDLCVCSTPGLRIAEMDEKELLRKAVTKQQRAGILEIFFRQLFAQVLDINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYISFREFLDILVVFMKGSPQDKSRLMFTMYDLDGNGFLSKEEFFTMMRSFIEISNNCLSKDQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTGDIFKQSNACRVSFLTRTPGNRVMAPSPRLYTEALQEKMQRGFLAQKLKQFKRFVENYRRHIVCVTIFSAICAGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRWIAMAAVVLAVVHSLGHAVNVYIFSVSPLSLMTCVFPSVFVNDGSKLPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYALIIIHGSYALIQLPSFHIYFLVPAIIYVGDKLVSLSRKKVEISVVKVELLPSGVTYLQFQRPKTFEYKSGQWVRIACLSLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPVGGTSARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGTQMLCKKIYFIWVTRTQRQFEWLADIIREVEENGSRDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSVTHFGRPPFELFLDSLQEVHPQVHKIGVFSCGPPGMTKNVEKACQLINRQDRAHFVHHYENF

Target ORF information:

RefSeq Version	NM_024141.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual oxidase 2 (Duox2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024141.1

ORF Insert Sequence:

ATGCTTCCAA CAAGTCTCAA GACATTGGTG CTCCTGGGCG CTCTGTTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA TGCACCCTCA CTGCCCCGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTCAAGTA CCACCAGCGC GGTGCAGCTG GCTCGCAGCT GCGTCGCCTA 
GTACCTGCTA ATTACGCTGA CGGTGTTTAT CAGGCTCTGC AGGAGCCGCT ACTCCCCAAC 
GCTCGCCTGC TAAGCGACGC TGTCAGTAAG GGCAAAGCAG GGCTGCCCTC GGCGCACAAC 
CGCACAGTGC TTGGGCTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCAGTGTTT 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAGA GGAGCCGCTG GGACCGCAGC 
ACTGGACAGA GCCCTAGCAA CCCCCGAGAC CTGACCAACC AGGTGACTGG CTGGTTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGCGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGCCC TGACCCTGCT TTCCCGAGGA ACTCCCAGAA CTCTCTGCTC 
ATGTGGATGG CACCAGACCC CGCCACGGGG CAGGGCGGGC CACAGGGGCT GTATGCCTTC 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCAC TGGGCTTGTT GTGGTTTCGA 
TACCACAACC TGTGTGCCAA GAGGCTGGCG CAGGAGCACC CACACTGGGG GGATGAGGAG 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACTTACC AGAACATTGC TCTATACCAA 
TGGTTGCCCA GCTTCCTGCA GAAAACACCC CCAGAGTATT CCGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCAGA GTTCGTGGCG GCCTCAGAGC AGTTCCTCTC TACCATGGTG 
CCCCCGGGGG TCTATATGAG AAACTCCAGC TGTCACTTCC GGGAATTCCC AAAGGAAGGT 
TCCAGCAGCT CTCCAGCTCT CAGGGTCTGC AACAACTACT GGATTCGGGA GAACCCCAGT 
CTGAAGACTG CTCAGGACGT GGACCAGCTG CTGCTGGGAA TGGCTTCCCA GATTTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGATCTG AGAGATTACT GGCCTGGCCC AGACAGATAC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGAGTGGCC GAGATATGGG GCTGCCCAGT 
TATAGCCAGG CTCTGCAGGC CTTAGGACTG GAGCCTCCCA AGAATTGGAG TGCTCTCAAC 
CCCAAAGTGG ATCCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CGGTTGGAAC TATTCCTGGG AGGGCTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTAAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ACGGGCTGTT CTCCAAGGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAGCC CAATGTTTTC 
TTCTGGCAAG AAGGTGCACC CTGCCCACAG CCTCAGCAAC TCACAACTGA AGGCTTGCCC 
CAGTGTGTGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACCCTCCTGG CTGTCTGCTG CTTTCCAGTA GTGAGTCTGA TTATTGCTTG GGTGGTGGCT 
CGTTTCCGGA ACCGAGAACG CAAGATGCTA CTAAAGAAAG GCAAGGAGAG TCTAAAGAAA 
CAGACAGCCA GTGATGGAGT ACCAGCGATG GAGTGGCCAG GCCCCAAGGA GAGCAGCTAC 
CCAGTCACTG TCCAGCTGCT TCCAGACAGG AGTCTGAAGG TCCTTGACAA AAGGCTCACT 
GTGCTCCGTA CCATCCAACT GCAGCCCACA CAGCAGGTCA ACCTCATCCT GTCCAGCAGC 
CATGGACGCC GCACCCTGTT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGA TGCCTTCGTG CAGCTGTTGC AAGACCTCTG CGTCTGCTCC 
ACTCCCGGCC TCCGCATAGC TGAGATGGAT GAGAAGGAGC TACTGAGAAA GGCTGTGACC 
AAGCAGCAGC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAATC AGGCCGACGC AGGGACTCTG CCTCTGGACT CATCCCAGCA AGTACGAGAG 
GCTCTGACCT GTGAACTGAG CAGAGCGGAG TTTGCGGACT CCCTGGGCCT CAAGCCCCAG 
GATATGTTTG TGGAGTCCAT GTTTTCTCTG GCCGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTT TTCATGAAAG GTTCCCCACA GGACAAGTCT 
CGCCTAATGT TTACCATGTA TGACCTGGAT GGAAATGGCT TTCTCTCCAA GGAGGAATTC 
TTCACCATGA TGCGGTCCTT CATCGAGATC TCCAACAACT GCCTGTCCAA GGACCAGCTG 
GCTGAGGTGG TGGAATCCAT GTTCCGGGAG TCGGGCTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCATTTCAT GCTGCGCGAC CACGACAGCG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGGGCTGG AGGCACCGGG GACATCTTTA AGCAAAGCAA TGCCTGTCGA 
GTCTCATTCC TCACCCGGAC TCCTGGGAAC AGGGTAATGG CTCCCTCTCC CCGGCTGTAC 
ACGGAAGCAC TGCAGGAGAA AATGCAGAGG GGCTTCCTAG CCCAGAAGCT CAAGCAGTTC 
AAGCGGTTTG TGGAAAACTA CCGGCGCCAC ATCGTGTGTG TTACAATCTT CTCAGCCATC 
TGCGCAGGCC TGTTTGCAGA CCGTGCCTAC TACTATGGCT TTGCCTCGCC ACCCACGGAC 
ATTGAAGAAA CCACCTATGT GGGCATCATC CTGTCCCGGG GCACAGCAGC CAGCATCTCC 
TTCATGTTCT CCTACATCCT GCTCACCATG TGCCGCAACC TCATCACCTT CCTGCGGGAG 
ACCTTCCTCA ACCGCTACAT TCCCTTTGAT GCCGCTGTGG ACTTCCACCG CTGGATCGCC 
ATGGCTGCGG TTGTCCTAGC TGTTGTGCAC AGTCTTGGAC ATGCAGTCAA CGTGTACATC 
TTCTCAGTCA GTCCCCTCAG CCTGATGACC TGCGTCTTCC CTAGTGTCTT TGTGAATGAT 
GGGTCCAAGC TTCCCCCAAA GTACTACTGG TGGTTCTTCG AGACAGTTCC AGGTATGACA 
GGAGTACTCC TGCTCCTGGT CCTGGCTATC ATGTATGTGT TTGCCTCCCA CCACTTCCGC 
CGCCACAGTT TCCGGGGCTT CTGGTTGACC CACCACCTCT ATGTTGTGCT TTATGCCCTG 
ATCATCATCC ATGGCAGCTA TGCCCTCATC CAATTACCCA GCTTCCACAT CTACTTCCTG 
GTCCCCGCCA TTATCTATGT GGGGGACAAG CTGGTGAGCC TGAGCCGGAA GAAGGTGGAG 
ATCAGTGTGG TGAAGGTTGA GCTGCTGCCT TCAGGGGTGA CCTATCTGCA GTTCCAGCGG 
CCCAAGACTT TTGAGTACAA ATCCGGGCAG TGGGTGCGGA TCGCTTGCTT GAGTCTGGGA 
ACCAATGAGT ACCACCCCTT CACGCTGACC TCCGCACCCC ATGAGGACAC ACTCAGCCTG 
CACATCCGGG CTGTGGGACC TTGGACTACT CGCCTCAGGG AGATCTACTC ACCTCCAGTG 
GGTGGCACCA GCGCCAGATA CCCAAAGCTG TACCTCGATG GACCATTCGG AGAGGGCCAC 
CAGGAATGGC ACAAGTTTGA GGTGTCGGTG CTGGTAGGAG GGGGCATTGG GGTCACCCCC 
TTTGCCTCCA TCCTCAAAGA CCTGGTCTTC AAATCGTCCA TGGGTACCCA GATGCTATGT 
AAGAAGATCT ACTTCATCTG GGTGACAAGG ACTCAGCGGC AGTTTGAGTG GCTGGCTGAC 
ATCATCCGGG AAGTGGAGGA GAATGGCAGC CGGGACCTGG TGTCTGTGCA CATCTATATC 
ACTCAGCTGG CTGAGAAGTT TGACCTCAGG ACGACCATGC TGTACATCTG TGAGAGGCAC 
TTCCAGAAGG TGCTGAACAG GAGTCTGTTC ACGGGCCTGC GCTCTGTCAC CCACTTTGGT 
CGCCCTCCCT TTGAGCTCTT CTTAGACTCT CTGCAGGAGG TTCATCCACA GGTACATAAG 
ATTGGTGTGT TCAGCTGTGG TCCTCCAGGG ATGACCAAGA ATGTGGAGAA GGCCTGTCAG 
CTCATCAACA GGCAGGACCG GGCCCACTTT GTGCATCATT ATGAGAACTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Duox2 ( XM_006234862.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234924.1 Rattus norvegicus dual oxidase 2 (Duox2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa26289
Clone ID Related Accession (Same CDS sequence)	XM_006234862.3
Accession Version	XM_006234862.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4821bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual oxidase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234862.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAGGA AGCTAGCAGC CAAGGACAAG AATACCAGGA TAACGATGAG CAGCGCGGTG 
GCGCGAGCTG ACACCTGCGA GACTGCACGC AGAGAGGAGG GTGAAAGTGC ATCCAGGAAG 
GTGAAGATTC TTGGAGCCCC GGGCAGGGAG CGGAGAAGAG AAACAAAATC TCCAAGTACA 
CGGAAGACTG TTGAACCCGA ACCGGAGCAT TACACCAGGA CCAACTGTGG GAGTGTGTGT 
CCTCCCGCCG CCGGGATCAA GGACAGCATG CTTCCAACAA GTCTCAAGAC ATTGGTGCTC 
CTGGGCGCTC TGTTGACTGG ACCCCTGGGT CCAGCAGGTG GCCAGGATGC ACCCTCACTG 
CCCTGGGAAG TGCAGCGCTA CGACGGCTGG TTTAATAATC TCAAGTACCA CCAGCGCGGT 
GCAGCTGGCT CGCAGCTGCG TCGCCTAGTA CCTGCTAATT ACGCTGACGG TGTTTATCAG 
GCTCTGCAGG AGCCGCTACT CCCCAACGCT CGCCTGCTAA GCGACGCTGT CAGTAAGGGC 
AAAGCAGGGC TGCCCTCGGC GCACAACCGC ACAGTGCTTG GGCTCTTCTT TGGCTATCAC 
GTGCTCTCAG ACCTGGTGAG TGTGGAAACA CCAGGCTGCC CCGCAGAGTT CCTCAACATT 
TACATCCCAC GTGGGGACCC AGTGTTTGAC CCTGACAAGC GCGGGAACGT GGTGCTGCCC 
TTTCAGAGGA GCCGCTGGGA CCGCAGCACT GGACAGAGCC CTAGCAACCC CCGAGACCTG 
ACCAACCAGG TGACTGGCTG GCTAGATGGC AGCGCCATCT ATGGCTCCTC TCATTCCTGG 
AGCGACACTC TGAGGAGCTT CTCTGGAGGA CAGCTGGCTT CTGGCCCTGA CCCTGCTTTC 
CCGAGGAACT CCCAGAACTC TCTGCTCATG TGGATGGCAC CAGACCCCGC CACGGGGCAG 
GGCGGGCCAC AGGGGCTGTA TGCCTTCGGG GCCCAGCGCG GGAACAGGGA GCCCTTTCTG 
CAGGCACTGG GCTTGTTGTG GTTTCGATAC CACAACCTGT GTGCCAAGAG GCTGGCGCAG 
GAGCACCCAC ACTGGGGGGA TGAGGAGCTG TTCCAGCATG CTCGCAAGAG GGTCATTGCC 
ACTTACCAGA ACATTGCTCT ATACCAATGG TTGCCCAGCT TCCTGCAGAA AACACCCCCA 
GAGTATTCCG GGTACCGCCC TTTCATGGAC CCCAGCATCT CCCCAGAGTT CGTGGCGGCC 
TCAGAGCAGT TCCTCTCTAC CATGGTGCCC CCGGGGGTCT ATATGAGAAA CTCCAGCTGT 
CACTTCCGGG AATTCCCAAA GGAAGGTTCC AGCAGCTCTC CAGCTCTCAG GGTCTGCAAC 
AACTACTGGA TTCGGGAGAA CCCCAGTCTG AAGACTGCTC AGGACGTGGA CCAGCTGCTG 
CTGGGAATGG CTTCCCAGAT TTCAGAGCTG GAGGACAGGA TAGTGATTGA AGATCTGAGA 
GATTACTGGC CTGGCCCAGA CAGATACTCT CGCACAGACT ACGTGGCTAG CAGTATCCAG 
AGTGGCCGAG ATATGGGGCT GCCCAGTTAT AGCCAGGCTC TGCAGGCCTT AGGACTGGAG 
CCTCCCAAGA ATTGGAGTGC TCTCAACCCC AAAGTGGATC CCCAGGTGCT GGAGGCCACA 
GCTGCTCTGT ACAACCAGGA CCTGTCCCGG TTGGAACTAT TCCTGGGAGG GCTCCTGGAG 
AGCCATGGGG ACCCTGGACC TCTATTCAGC AACATCATTC TTGACCAGTT TGTAAGGCTC 
CGGGATGGTG ATCGCTACTG GTTTGAGAAC ACTAGGAACG GGCTGTTCTC CAAGGAGGAG 
ATTGCAGAAA TCAGAAACAC CACCTTGCGG GATGTACTGG TAGCTGTCTC CAATGTGGAC 
CCCAGTGCCT TGCAGCCCAA TGTTTTCTTC TGGCAAGAAG GTGCACCCTG CCCACAGCCT 
CAGCAACTCA CAACTGAAGG CTTGCCCCAG TGTGTGCCTG TTACTGTGAT TGACTACTTT 
GAGGGCAGTG GTGCTGGCTA TGGTGTCACC CTCCTGGCTG TCTGCTGCTT TCCAGTAGTG 
AGTCTGATTA TTGCTTGGGT GGTGGCTCGT TTCCGGAACC GAGAACGCAA GATGCTACTA 
AAGAAAGGCA AGGAGAGTCT AAAGAAACAG ACAGCCAGTG ATGGAGTACC AGCGATGGAG 
TGGCCAGGCC CCAAGGAGAG CAGCTACCCA GTCACTGTCC AGCTGCTTCC AGACAGGAGT 
CTGAAGGTCC TTGACAAAAG GCTCACTGTG CTCCGTACCA TCCAACTGCA GCCCACACAG 
CAGGTCAACC TCATCCTGTC CAGCAGCCAT GGACGCCGCA CCCTGTTGCT CAAGATCCCC 
AAGGAGTACG ACCTGGTGCT GATGTTTAAC TCTGAAGAGG ACCGGGATGC CTTCGTGCAG 
CTGTTGCAAG ACCTCTGCGT CTGCTCCACT CCCGGCCTCC GCATAGCTGA GATGGATGAG 
AAGGAGCTAC TGAGAAAGGC TGTGACCAAG CAGCAGCGGG CAGGCATCTT GGAGATCTTC 
TTCAGACAGC TTTTTGCTCA GGTGCTGGAC ATCAATCAGG CCGACGCAGG GACTCTGCCT 
CTGGACTCAT CCCAGCAAGT ACGAGAGGCT CTGACCTGTG AACTGAGCAG AGCGGAGTTT 
GCGGACTCCC TGGGCCTCAA GCCCCAGGAT ATGTTTGTGG AGTCCATGTT TTCTCTGGCC 
GACAAGGATG GCAATGGCTA CATATCCTTC CGGGAGTTCC TGGACATCCT GGTGGTTTTC 
ATGAAAGGTT CCCCACAGGA CAAGTCTCGC CTAATGTTTA CCATGTATGA CCTGGATGGA 
AATGGCTTTC TCTCCAAGGA GGAATTCTTC ACCATGATGC GGTCCTTCAT CGAGATCTCC 
AACAACTGCC TGTCCAAGGA CCAGCTGGCT GAGGTGGTGG AATCCATGTT CCGGGAGTCG 
GGCTTCCAGG ATAAGGAGGA GCTGACCTGG GAGGACTTCC ATTTCATGCT GCGCGACCAC 
GACAGCGATC TCCGATTCAC ACAGCTCTGT GTCAAAGGTG GGGCTGGAGG CACCGGGGAC 
ATCTTTAAGC AAAGCAATGC CTGTCGAGTC TCATTCCTCA CCCGGACTCC TGGGAACAGG 
GTAATGGCTC CCTCTCCCCG GCTGTACACG GAAGCACTGC AGGAGAAAAT GCAGAGGGGC 
TTCCTAGCCC AGAAGCTCAA GCAGTTCAAG CGGTTTGTGG AAAACTACCG GCGCCACATC 
GTGTGTGTTA CAATCTTCTC AGCCATCTGC GCAGGCCTGT TTGCAGACCG TGCCTACTAC 
TATGGCTTTG CCTCGCCACC CACGGACATT GAAGAAACCA CCTATGTGGG CATCATCCTG 
TCCCGGGGCA CAGCAGCCAG CATCTCCTTC ATGTTCTCCT ACATCCTGCT CACCATGTGC 
CGCAACCTCA TCACCTTCCT GCGGGAGACC TTCCTCAACC GCTACATTCC CTTTGATGCT 
GCTGTGGACT TCCACCGCTG GATCGCCATG GCTGCAGTTG TCCTAGCTGT TGTGCACAGT 
CTTGGACATG CAGTCAACGT GTACATCTTC TCAGTCAGTC CCCTCAGCCT GATGACCTGC 
GTCTTCCCTA GTGTCTTTGT GAATGATGGG TCCAAGCTTC CCCCAAAGTA CTACTGGTGG 
TTCTTCGAGA CAGTTCCAGG TATGACAGGA GTACTCCTGC TCCTGGTCCT GGCTATCATG 
TATGTGTTTG CCTCCCACCA CTTCCGCCGC CACAGTTTCC GGGGCTTCTG GTTGACCCAC 
CACCTCTATG TTGTGCTTTA TGCCCTGATC ATCATCCATG GCAGCTATGC CCTCATCCAA 
TTACCCAGCT TCCACATCTA CTTCCTGGTC CCCGCCATTA TCTATGTGGG GGACAAGCTG 
GTGAGCCTGA GCCGGAAGAA GGTGGAGATC AGTGTGGTGA AGGCTGAGCT GCTGCCTTCA 
GGGGTGACCT ATCTGCAGTT CCAGCGGCCC AAGACTTTTG AGTACAAATC CGGGCAGTGG 
GTGCGGATCG CTTGCTTGAG TCTGGGAACC AATGAGTACC ACCCCTTCAC GCTGACCTCC 
GCACCCCATG AGGACACACT CAGCCTGCAC ATCCGGGCTG TGGGACCTTG GACTACTCGC 
CTCAGGGAGA TCTACTCACC TCCAGTGGGT GGCACCAGCG CCAGATACCC AAAGCTGTAC 
CTCGATGGAC CATTCGGAGA GGGCCACCAG GAATGGCACA AGTTTGAGGT GTCGGTGCTG 
GTAGGAGGGG GCATTGGGGT CACCCCCTTT GCCTCCATCC TCAAAGACCT GGTCTTCAAA 
TCGTCCATGG GTGCCCAGAT GCTATGTAAG AAGATCTACT TCATCTGGGT GACAAGGACT 
CAGCGGCAGT TTGAGTGGCT GGCTGACATC ATCCGGGAAG TGGAGGAGAA TGACAGCCGG 
GACCTGGTGT CTGTGCACAT CTATATCACT CAGCTGGCTG AGAAGTTTGA CCTCAGGACG 
ACCATGCTGT ACATCTGTGA GAGGCACTTC CAGAAGGTGC TGAACAGGAG TCTGTTCACG 
GGCCTGCGCT CTGTCACCCA CTTTGGTCGC CCTCCCTTTG AGCTCTTCTT AGACTCTCTG 
CAGGAGGTTC ATCCACAGGT ACATAAGATT GGTGTGTTCA GCTGTGGTCC TCCAGGGATG 
ACCAAGAATG TGGAGAAGGC CTGTCAGCTC ATCAACAGGC AGGACCGGGC CCACTTTGTG 
CATCATTATG AGAACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234924.1
CDS	970..5790
Translation	MNRKLAAKDKNTRITMSSAVARADTCETARREEGESASRKVKILGAPGRERRRETKSPSTRKTVEPEPEHYTRTNCGSVCPPAAGIKDSMLPTSLKTLVLLGALLTGPLGPAGGQDAPSLPWEVQRYDGWFNNLKYHQRGAAGSQLRRLVPANYADGVYQALQEPLLPNARLLSDAVSKGKAGLPSAHNRTVLGLFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDRSTGQSPSNPRDLTNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQNSLLMWMAPDPATGQGGPQGLYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNIALYQWLPSFLQKTPPEYSGYRPFMDPSISPEFVAASEQFLSTMVPPGVYMRNSSCHFREFPKEGSSSSPALRVCNNYWIRENPSLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPDRYSRTDYVASSIQSGRDMGLPSYSQALQALGLEPPKNWSALNPKVDPQVLEATAALYNQDLSRLELFLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPQQLTTEGLPQCVPVTVIDYFEGSGAGYGVTLLAVCCFPVVSLIIAWVVARFRNRERKMLLKKGKESLKKQTASDGVPAMEWPGPKESSYPVTVQLLPDRSLKVLDKRLTVLRTIQLQPTQQVNLILSSSHGRRTLLLKIPKEYDLVLMFNSEEDRDAFVQLLQDLCVCSTPGLRIAEMDEKELLRKAVTKQQRAGILEIFFRQLFAQVLDINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYISFREFLDILVVFMKGSPQDKSRLMFTMYDLDGNGFLSKEEFFTMMRSFIEISNNCLSKDQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTGDIFKQSNACRVSFLTRTPGNRVMAPSPRLYTEALQEKMQRGFLAQKLKQFKRFVENYRRHIVCVTIFSAICAGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRWIAMAAVVLAVVHSLGHAVNVYIFSVSPLSLMTCVFPSVFVNDGSKLPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYALIIIHGSYALIQLPSFHIYFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPKTFEYKSGQWVRIACLSLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPVGGTSARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGAQMLCKKIYFIWVTRTQRQFEWLADIIREVEENDSRDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSVTHFGRPPFELFLDSLQEVHPQVHKIGVFSCGPPGMTKNVEKACQLINRQDRAHFVHHYENF

Target ORF information:

RefSeq Version	XM_006234862.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual oxidase 2 (Duox2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234862.3

ORF Insert Sequence:

ATGAACAGGA AGCTAGCAGC CAAGGACAAG AATACCAGGA TAACGATGAG CAGCGCGGTG 
GCGCGAGCTG ACACCTGCGA GACTGCACGC AGAGAGGAGG GTGAAAGTGC ATCCAGGAAG 
GTGAAGATTC TTGGAGCCCC GGGCAGGGAG CGGAGAAGAG AAACAAAATC TCCAAGTACA 
CGGAAGACTG TTGAACCCGA ACCGGAGCAT TACACCAGGA CCAACTGTGG GAGTGTGTGT 
CCTCCCGCCG CCGGGATCAA GGACAGCATG CTTCCAACAA GTCTCAAGAC ATTGGTGCTC 
CTGGGCGCTC TGTTGACTGG ACCCCTGGGT CCAGCAGGTG GCCAGGATGC ACCCTCACTG 
CCCTGGGAAG TGCAGCGCTA CGACGGCTGG TTTAATAATC TCAAGTACCA CCAGCGCGGT 
GCAGCTGGCT CGCAGCTGCG TCGCCTAGTA CCTGCTAATT ACGCTGACGG TGTTTATCAG 
GCTCTGCAGG AGCCGCTACT CCCCAACGCT CGCCTGCTAA GCGACGCTGT CAGTAAGGGC 
AAAGCAGGGC TGCCCTCGGC GCACAACCGC ACAGTGCTTG GGCTCTTCTT TGGCTATCAC 
GTGCTCTCAG ACCTGGTGAG TGTGGAAACA CCAGGCTGCC CCGCAGAGTT CCTCAACATT 
TACATCCCAC GTGGGGACCC AGTGTTTGAC CCTGACAAGC GCGGGAACGT GGTGCTGCCC 
TTTCAGAGGA GCCGCTGGGA CCGCAGCACT GGACAGAGCC CTAGCAACCC CCGAGACCTG 
ACCAACCAGG TGACTGGCTG GCTAGATGGC AGCGCCATCT ATGGCTCCTC TCATTCCTGG 
AGCGACACTC TGAGGAGCTT CTCTGGAGGA CAGCTGGCTT CTGGCCCTGA CCCTGCTTTC 
CCGAGGAACT CCCAGAACTC TCTGCTCATG TGGATGGCAC CAGACCCCGC CACGGGGCAG 
GGCGGGCCAC AGGGGCTGTA TGCCTTCGGG GCCCAGCGCG GGAACAGGGA GCCCTTTCTG 
CAGGCACTGG GCTTGTTGTG GTTTCGATAC CACAACCTGT GTGCCAAGAG GCTGGCGCAG 
GAGCACCCAC ACTGGGGGGA TGAGGAGCTG TTCCAGCATG CTCGCAAGAG GGTCATTGCC 
ACTTACCAGA ACATTGCTCT ATACCAATGG TTGCCCAGCT TCCTGCAGAA AACACCCCCA 
GAGTATTCCG GGTACCGCCC TTTCATGGAC CCCAGCATCT CCCCAGAGTT CGTGGCGGCC 
TCAGAGCAGT TCCTCTCTAC CATGGTGCCC CCGGGGGTCT ATATGAGAAA CTCCAGCTGT 
CACTTCCGGG AATTCCCAAA GGAAGGTTCC AGCAGCTCTC CAGCTCTCAG GGTCTGCAAC 
AACTACTGGA TTCGGGAGAA CCCCAGTCTG AAGACTGCTC AGGACGTGGA CCAGCTGCTG 
CTGGGAATGG CTTCCCAGAT TTCAGAGCTG GAGGACAGGA TAGTGATTGA AGATCTGAGA 
GATTACTGGC CTGGCCCAGA CAGATACTCT CGCACAGACT ACGTGGCTAG CAGTATCCAG 
AGTGGCCGAG ATATGGGGCT GCCCAGTTAT AGCCAGGCTC TGCAGGCCTT AGGACTGGAG 
CCTCCCAAGA ATTGGAGTGC TCTCAACCCC AAAGTGGATC CCCAGGTGCT GGAGGCCACA 
GCTGCTCTGT ACAACCAGGA CCTGTCCCGG TTGGAACTAT TCCTGGGAGG GCTCCTGGAG 
AGCCATGGGG ACCCTGGACC TCTATTCAGC AACATCATTC TTGACCAGTT TGTAAGGCTC 
CGGGATGGTG ATCGCTACTG GTTTGAGAAC ACTAGGAACG GGCTGTTCTC CAAGGAGGAG 
ATTGCAGAAA TCAGAAACAC CACCTTGCGG GATGTACTGG TAGCTGTCTC CAATGTGGAC 
CCCAGTGCCT TGCAGCCCAA TGTTTTCTTC TGGCAAGAAG GTGCACCCTG CCCACAGCCT 
CAGCAACTCA CAACTGAAGG CTTGCCCCAG TGTGTGCCTG TTACTGTGAT TGACTACTTT 
GAGGGCAGTG GTGCTGGCTA TGGTGTCACC CTCCTGGCTG TCTGCTGCTT TCCAGTAGTG 
AGTCTGATTA TTGCTTGGGT GGTGGCTCGT TTCCGGAACC GAGAACGCAA GATGCTACTA 
AAGAAAGGCA AGGAGAGTCT AAAGAAACAG ACAGCCAGTG ATGGAGTACC AGCGATGGAG 
TGGCCAGGCC CCAAGGAGAG CAGCTACCCA GTCACTGTCC AGCTGCTTCC AGACAGGAGT 
CTGAAGGTCC TTGACAAAAG GCTCACTGTG CTCCGTACCA TCCAACTGCA GCCCACACAG 
CAGGTCAACC TCATCCTGTC CAGCAGCCAT GGACGCCGCA CCCTGTTGCT CAAGATCCCC 
AAGGAGTACG ACCTGGTGCT GATGTTTAAC TCTGAAGAGG ACCGGGATGC CTTCGTGCAG 
CTGTTGCAAG ACCTCTGCGT CTGCTCCACT CCCGGCCTCC GCATAGCTGA GATGGATGAG 
AAGGAGCTAC TGAGAAAGGC TGTGACCAAG CAGCAGCGGG CAGGCATCTT GGAGATCTTC 
TTCAGACAGC TTTTTGCTCA GGTGCTGGAC ATCAATCAGG CCGACGCAGG GACTCTGCCT 
CTGGACTCAT CCCAGCAAGT ACGAGAGGCT CTGACCTGTG AACTGAGCAG AGCGGAGTTT 
GCGGACTCCC TGGGCCTCAA GCCCCAGGAT ATGTTTGTGG AGTCCATGTT TTCTCTGGCC 
GACAAGGATG GCAATGGCTA CATATCCTTC CGGGAGTTCC TGGACATCCT GGTGGTTTTC 
ATGAAAGGTT CCCCACAGGA CAAGTCTCGC CTAATGTTTA CCATGTATGA CCTGGATGGA 
AATGGCTTTC TCTCCAAGGA GGAATTCTTC ACCATGATGC GGTCCTTCAT CGAGATCTCC 
AACAACTGCC TGTCCAAGGA CCAGCTGGCT GAGGTGGTGG AATCCATGTT CCGGGAGTCG 
GGCTTCCAGG ATAAGGAGGA GCTGACCTGG GAGGACTTCC ATTTCATGCT GCGCGACCAC 
GACAGCGATC TCCGATTCAC ACAGCTCTGT GTCAAAGGTG GGGCTGGAGG CACCGGGGAC 
ATCTTTAAGC AAAGCAATGC CTGTCGAGTC TCATTCCTCA CCCGGACTCC TGGGAACAGG 
GTAATGGCTC CCTCTCCCCG GCTGTACACG GAAGCACTGC AGGAGAAAAT GCAGAGGGGC 
TTCCTAGCCC AGAAGCTCAA GCAGTTCAAG CGGTTTGTGG AAAACTACCG GCGCCACATC 
GTGTGTGTTA CAATCTTCTC AGCCATCTGC GCAGGCCTGT TTGCAGACCG TGCCTACTAC 
TATGGCTTTG CCTCGCCACC CACGGACATT GAAGAAACCA CCTATGTGGG CATCATCCTG 
TCCCGGGGCA CAGCAGCCAG CATCTCCTTC ATGTTCTCCT ACATCCTGCT CACCATGTGC 
CGCAACCTCA TCACCTTCCT GCGGGAGACC TTCCTCAACC GCTACATTCC CTTTGATGCT 
GCTGTGGACT TCCACCGCTG GATCGCCATG GCTGCAGTTG TCCTAGCTGT TGTGCACAGT 
CTTGGACATG CAGTCAACGT GTACATCTTC TCAGTCAGTC CCCTCAGCCT GATGACCTGC 
GTCTTCCCTA GTGTCTTTGT GAATGATGGG TCCAAGCTTC CCCCAAAGTA CTACTGGTGG 
TTCTTCGAGA CAGTTCCAGG TATGACAGGA GTACTCCTGC TCCTGGTCCT GGCTATCATG 
TATGTGTTTG CCTCCCACCA CTTCCGCCGC CACAGTTTCC GGGGCTTCTG GTTGACCCAC 
CACCTCTATG TTGTGCTTTA TGCCCTGATC ATCATCCATG GCAGCTATGC CCTCATCCAA 
TTACCCAGCT TCCACATCTA CTTCCTGGTC CCCGCCATTA TCTATGTGGG GGACAAGCTG 
GTGAGCCTGA GCCGGAAGAA GGTGGAGATC AGTGTGGTGA AGGCTGAGCT GCTGCCTTCA 
GGGGTGACCT ATCTGCAGTT CCAGCGGCCC AAGACTTTTG AGTACAAATC CGGGCAGTGG 
GTGCGGATCG CTTGCTTGAG TCTGGGAACC AATGAGTACC ACCCCTTCAC GCTGACCTCC 
GCACCCCATG AGGACACACT CAGCCTGCAC ATCCGGGCTG TGGGACCTTG GACTACTCGC 
CTCAGGGAGA TCTACTCACC TCCAGTGGGT GGCACCAGCG CCAGATACCC AAAGCTGTAC 
CTCGATGGAC CATTCGGAGA GGGCCACCAG GAATGGCACA AGTTTGAGGT GTCGGTGCTG 
GTAGGAGGGG GCATTGGGGT CACCCCCTTT GCCTCCATCC TCAAAGACCT GGTCTTCAAA 
TCGTCCATGG GTGCCCAGAT GCTATGTAAG AAGATCTACT TCATCTGGGT GACAAGGACT 
CAGCGGCAGT TTGAGTGGCT GGCTGACATC ATCCGGGAAG TGGAGGAGAA TGACAGCCGG 
GACCTGGTGT CTGTGCACAT CTATATCACT CAGCTGGCTG AGAAGTTTGA CCTCAGGACG 
ACCATGCTGT ACATCTGTGA GAGGCACTTC CAGAAGGTGC TGAACAGGAG TCTGTTCACG 
GGCCTGCGCT CTGTCACCCA CTTTGGTCGC CCTCCCTTTG AGCTCTTCTT AGACTCTCTG 
CAGGAGGTTC ATCCACAGGT ACATAAGATT GGTGTGTTCA GCTGTGGTCC TCCAGGGATG 
ACCAAGAATG TGGAGAAGGC CTGTCAGCTC ATCAACAGGC AGGACCGGGC CCACTTTGTG 
CATCATTATG AGAACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

When an Intramolecular Disulfide Bridge Governs the Interaction of DUOX2 with Its Partner DUOXA2.
Antioxidants & redox signaling23(9)724-33(2015 Sep)
Carré A,Louzada RA,Fortunato RS,Ameziane-El-Hassani R,Morand S,Ogryzko V,de Carvalho DP,Grasberger H,Leto TL,Dupuy C

New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells.
PloS one8(5)e62849(2013)
Fernández LP,López-Márquez A,Martínez AM,Gómez-López G,Santisteban P

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.
Experimental cell research318(18)2353-64(2012 Nov)
Hoste C,Dumont JE,Miot F,De Deken X

Identification and functional analysis of novel dual oxidase 2 (DUOX2) mutations in children with congenital or subclinical hypothyroidism.
The Journal of clinical endocrinology and metabolism96(8)E1335-9(2011 Aug)
De Marco G,Agretti P,Montanelli L,Di Cosmo C,Bagattini B,De Servi M,Ferrarini E,Dimida A,Freitas Ferreira AC,Molinaro A,Ceccarelli C,Brozzi F,Pinchera A,Vitti P,Tonacchera M

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.
Journal of cell science122(Pt 8)1238-47(2009 Apr)
Luxen S,Noack D,Frausto M,Davanture S,Torbett BE,Knaus UG

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Duox2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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