Duox2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Duox2
Entrez Gene ID	214593
Full Name	dual oxidase 2
Synonyms	A430065P05Rik,LNOX2,NOXEF2,P138-TOX,THOX2
General protein information	Preferred Names dual oxidase 2 Names dual oxidase 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 E5

mRNA and Protein(s)

mRNA	Protein	Name
NM_001362755.1	NP_001349684.1	dual oxidase 2 precursor
NM_177610.2	NP_808278.2	dual oxidase 2 precursor
XM_006499110.2	XP_006499173.1	dual oxidase 2 isoform X1
XM_006499110.3	XP_006499173.1	dual oxidase 2 isoform X1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	LOC713906	XP_001103398.2
Canis lupus familiaris (dog)	DUOX2	XP_005638424.1
Rattus norvegicus (Norway rat)	Duox2	NP_077055.1
Bos taurus (cattle)	DUOX2	XP_002690988.2
Anopheles gambiae (African malaria mosquito)	DUOX	XP_319115.4
Homo sapiens (human)	DUOX2	NP_054799.4
Drosophila melanogaster (fruit fly)	Duox	NP_001259968.1
Caenorhabditis elegans (roundworm)	bli-3	NP_490686.3
Pan troglodytes (chimpanzee)	DUOX2	XP_510367.3
Arabidopsis thaliana (thale cress)	RBOHB	NP_973799.1
Mus musculus (house mouse)	Duox2	NP_808278.2
Caenorhabditis elegans (roundworm)	duox-2	NP_490684.1
Xenopus tropicalis (tropical clawed frog)	duox2	XP_002937935.1

Gene Ontology
Bibliography

Related articles in PubMed

CRISPR/Cas9-mediated modification of the extreme C-terminus impairs PDGF-stimulated activity of Duox2.
Tyurin-Kuzmin PA, Karagyaur MN, Rubtsov YP, Dyikanov DT, Vasiliev PA, Vorotnikov AV
Biological chemistry399(5)437-446(2018 04)

Chemiluminescence imaging of Duox2-derived hydrogen peroxide for longitudinal visualization of biological response to viral infection in nasal mucosa.
Kim HJ, Seo YH, An S, Jo A, Kwon IC, Kim S
Theranostics8(7)1798-1807(2018)

Intranasal delivery of Duox2 DNA using cationic polymer can prevent acute influenza A viral infection in vivo lung.
Kim BJ, Cho SW, Jeon YJ, An S, Jo A, Lim JH, Kim DY, Won TB, Han DH, Rhee CS, Kim HJ
Applied microbiology and biotechnology102(1)105-115(2018 Jan)

GPR43 activation enhances psoriasis-like inflammation through epidermal upregulation of IL-6 and dual oxidase 2 signaling in a murine model.
Nadeem A, Ahmad SF, Al-Harbi NO, El-Sherbeeny AM, Al-Harbi MM, Almukhlafi TS
Cellular signalling3359-68(2017 05)

Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium.
Chu FF, Esworthy RS, Doroshow JH, Grasberger H, Donko A, Leto TL, Gao Q, Shen B
Redox biology11144-156(2017 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Duox2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Duox2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu06540	NM_177610.2 Latest version!	Mus musculus dual oxidase 2 (Duox2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
OMu30225	NM_001362755.1 Latest version!	Mus musculus dual oxidase 2 (Duox2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
OMu30225	XM_006499110.3 Latest version!	Mus musculus dual oxidase 2 (Duox2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
View Old Accession Versions >>
OMu30225	XM_006499110.2	Mus musculus dual oxidase 2 (Duox2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Duox2 ( NM_177610.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_808278.2 Mus musculus dual oxidase 2 (Duox2), mRNA.

Price & Availability↑

CloneID	OMu06540
Clone ID Related Accession (Same CDS sequence)	NM_177610.2
Accession Version	NM_177610.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512403200000
Organism	Mus musculus(house mouse)
Product	dual oxidase 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL844566.8. On or before Feb 10, 2007 this sequence version replaced NM_001080983.1, NM_177610.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGGGTAATGG GGCCCTCTCC CCGGCTGTAC 
ACGGAGGCAC TGCAGGAGAA AAAACAGAGT GGCTTCCTGG CCCAGAAGTT CAAGCAGTAC 
AAGCGATTTG TGGAAAACTA CCGGCGCCAC ATTGTGTGTG TTACAATCTT CTCAGCCATC 
TGCATAGGCC TGTTTGCAGA CCGTGCCTAC TACTATGGCT TTGCCTCACC ACCCACGGAC 
ATCGAAGAAA CCACCTATGT GGGCATCATC CTGTCCCGGG GCACGGCGGC CAGCATCTCC 
TTCATGTTCT CCTACATCCT GCTCACCATG TGCCGCAACC TCATCACCTT CTTGCGGGAG 
ACCTTCCTCA ACCGCTACAT CCCCTTTGAT GCCGCTGTGG ACTTCCATCG CTGGATTGCT 
ATGGCTGCAG TTGTCCTAGC TGTTCTGCAC AGTGCTGGAC ATGCAGTCAA TGTGTACATT 
TTCTCAGTCA GTCCCCTCAG CCTGATGGCC TGCGTCTTCC CTAACGTCTT TGTGAATGAC 
GGGTCCAAGT TTCCCCCAAA GTACTACTGG TGGTTCTTTG AGACAGTTCC AGGTATGACA 
GGAGTCCTCC TGCTCCTGGT CCTGGCCATC ATGTACGTCT TCGCCTCCCA CCACTTCCGC 
CGCCACAGTT TCCGGGGCTT CTGGCTGACC CACCACCTCT ATGTTGTGCT TTATGTCCTG 
ATCATCATCC ATGGCAGCTA TGCCCTCATC CAATTACCCA GCTTCCACAT CTACTTCCTG 
GTCCCAGCAA TTATCTATGG AGGGGACAAG CTAGTGAGCC TGAGCCGGAA GAAGGTGGAG 
ATCAGTGTGG TGAAGGCGGA GCTGCTGCCT TCAGGGGTGA CCTACTTGCA GTTCCAGAGA 
CCCAAGACAT TTGAGTACAA ATCAGGGCAG TGGGTGCGAA TCGCGTGCCT GGATCTGGGT 
ACCAATGAGT ATCACCCCTT CACGCTGACC TCTGCACCCC ATGAGGACAC ACTCAGCCTG 
CACATCAGGG CTGTGGGACC TTGGACTACT CGCCTCAGAG AGATCTACTC ACCCCCAGTG 
GGTGGCACCT GTGCCAGATA CCCAAAGCTG TACCTCGATG GACCATTTGG AGAGGGCCAT 
CAGGAGTGGC ATAAGTTTGA GGTGTCAGTG CTGGTAGGAG GGGGCATTGG AGTCACCCCC 
TTTGCCTCCA TCCTCAAAGA CCTGGTCTTC AAATCGTCCA TGGGCAGCCA GATGCTCTGT 
AAGAAGATCT ACTTCATCTG GGTGACAAGG ACTCAGAGGC AGTTTGAGTG GCTGGCTGAC 
ATCATCCGGG AGGTGGAGGA GAATGACTGC CAGGACCTGG TGTCTGTGCA CATCTACATT 
ACTCAGCTGG CTGAGAAGTT CGACCTCAGG ACCACCATGC TGTACATCTG TGAGAGGCAC 
TTCCAGAAGG CGCTGAACAG GAGTTTGTTC ACGGGCCTGC GTTCCATCAC CCACTTTGGT 
CGCCCTCCCT TTGAGCTCTT CTTCAACTCT CTACAGGAAG TCCATCCACA GGTACGTAAG 
ATTGGAGTCT TCAGCTGTGG TCCTCCAGGG ATGACCAAGA ATGTGGAGAA GGCCTGCCAG 
CTCATCAACA GGCAGGACCG GGCCCACTTT GTGCATCATT ATGAGAACTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808278.2
CDS	1..4554
Translation	MLPTSPKTLVLLGALLTGPLGPAGGQDAPSLPWEVQRYDGWFNNLKYHQRGAAGSRLRRLIPANYADGVYQALEEPLLPNPRRLSDAVAKGKAGLPSVHNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDHNTGQSPSNPRDQSNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQSSLLMWMAPDPSTGRGGPQGVYAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPHWGDEELFQHARKRVIATYQNIALYQWLPSFLQKTPPEYSGYRPFMDPSISPEFVVASEQFLSTMVPPGVYMRNSSCHFRKFPKEGSDSSPALRVCNSYWIRENPNLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPERFSRTDYVASSIQRGRDMGLPSYSQALLALGLEPPKNWSALNPQVEPQVLEATAALYNQDLSQLELLLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPRQLTTDGLPQCAPVTVIDYFEGSGAGYGVTLVAVCCFPLVSLIVAGVVAHFRNREHKMLLKKGKESLKKQPASDGVPAMEWPGPKEKSYPVTLQLLPDRSLQVLDKRFTVLRTIQLQSPQQVNLILSSNSGRRTLLLKIPKEYDLVLMFNSEEDRGAFVRLLQDLCICCTPGLHIAEVDEKELLRKAVTKQQRAGILEIFFRQLFAQVLDINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYISFREFLDILVVFMKGSSEDKSRLMFTMYDLDGNGFLSKDEFFTMMRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTKDIFKQSSACRVSFINRTPGNRVMGPSPRLYTEALQEKKQSGFLAQKFKQYKRFVENYRRHIVCVTIFSAICIGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRWIAMAAVVLAVLHSAGHAVNVYIFSVSPLSLMACVFPNVFVNDGSKFPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYVLIIIHGSYALIQLPSFHIYFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPKTFEYKSGQWVRIACLDLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPVGGTCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGSQMLCKKIYFIWVTRTQRQFEWLADIIREVEENDCQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKALNRSLFTGLRSITHFGRPPFELFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRAHFVHHYENF

Target ORF information:

RefSeq Version	NM_177610.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual oxidase 2 (Duox2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177610.2

ORF Insert Sequence:

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGGGTAATGG GGCCCTCTCC CCGGCTGTAC 
ACGGAGGCAC TGCAGGAGAA AAAACAGAGT GGCTTCCTGG CCCAGAAGTT CAAGCAGTAC 
AAGCGATTTG TGGAAAACTA CCGGCGCCAC ATTGTGTGTG TTACAATCTT CTCAGCCATC 
TGCATAGGCC TGTTTGCAGA CCGTGCCTAC TACTATGGCT TTGCCTCACC ACCCACGGAC 
ATCGAAGAAA CCACCTATGT GGGCATCATC CTGTCCCGGG GCACGGCGGC CAGCATCTCC 
TTCATGTTCT CCTACATCCT GCTCACCATG TGCCGCAACC TCATCACCTT CTTGCGGGAG 
ACCTTCCTCA ACCGCTACAT CCCCTTTGAT GCCGCTGTGG ACTTCCATCG CTGGATTGCT 
ATGGCTGCAG TTGTCCTAGC TGTTCTGCAC AGTGCTGGAC ATGCAGTCAA TGTGTACATT 
TTCTCAGTCA GTCCCCTCAG CCTGATGGCC TGCGTCTTCC CTAACGTCTT TGTGAATGAC 
GGGTCCAAGT TTCCCCCAAA GTACTACTGG TGGTTCTTTG AGACAGTTCC AGGTATGACA 
GGAGTCCTCC TGCTCCTGGT CCTGGCCATC ATGTACGTCT TCGCCTCCCA CCACTTCCGC 
CGCCACAGTT TCCGGGGCTT CTGGCTGACC CACCACCTCT ATGTTGTGCT TTATGTCCTG 
ATCATCATCC ATGGCAGCTA TGCCCTCATC CAATTACCCA GCTTCCACAT CTACTTCCTG 
GTCCCAGCAA TTATCTATGG AGGGGACAAG CTAGTGAGCC TGAGCCGGAA GAAGGTGGAG 
ATCAGTGTGG TGAAGGCGGA GCTGCTGCCT TCAGGGGTGA CCTACTTGCA GTTCCAGAGA 
CCCAAGACAT TTGAGTACAA ATCAGGGCAG TGGGTGCGAA TCGCGTGCCT GGATCTGGGT 
ACCAATGAGT ATCACCCCTT CACGCTGACC TCTGCACCCC ATGAGGACAC ACTCAGCCTG 
CACATCAGGG CTGTGGGACC TTGGACTACT CGCCTCAGAG AGATCTACTC ACCCCCAGTG 
GGTGGCACCT GTGCCAGATA CCCAAAGCTG TACCTCGATG GACCATTTGG AGAGGGCCAT 
CAGGAGTGGC ATAAGTTTGA GGTGTCAGTG CTGGTAGGAG GGGGCATTGG AGTCACCCCC 
TTTGCCTCCA TCCTCAAAGA CCTGGTCTTC AAATCGTCCA TGGGCAGCCA GATGCTCTGT 
AAGAAGATCT ACTTCATCTG GGTGACAAGG ACTCAGAGGC AGTTTGAGTG GCTGGCTGAC 
ATCATCCGGG AGGTGGAGGA GAATGACTGC CAGGACCTGG TGTCTGTGCA CATCTACATT 
ACTCAGCTGG CTGAGAAGTT CGACCTCAGG ACCACCATGC TGTACATCTG TGAGAGGCAC 
TTCCAGAAGG CGCTGAACAG GAGTTTGTTC ACGGGCCTGC GTTCCATCAC CCACTTTGGT 
CGCCCTCCCT TTGAGCTCTT CTTCAACTCT CTACAGGAAG TCCATCCACA GGTACGTAAG 
ATTGGAGTCT TCAGCTGTGG TCCTCCAGGG ATGACCAAGA ATGTGGAGAA GGCCTGCCAG 
CTCATCAACA GGCAGGACCG GGCCCACTTT GTGCATCATT ATGAGAACTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Duox2 ( NM_001362755.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001349684.1 Mus musculus dual oxidase 2 (Duox2), mRNA.

Price & Availability↑

CloneID	OMu30225
Clone ID Related Accession (Same CDS sequence)	NM_001362755.1 , XM_006499110.2 , XM_006499110.3
Accession Version	NM_001362755.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571846400000
Organism	Mus musculus(house mouse)
Product	dual oxidase 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL844566.8. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC172138.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGTTCCTGCC CCCCAGAAAC GGCACTCTCT 
GACATGGAAA CCCCAGAACT GGGAAGTACT GGCCTAAAGA AGAGGTTTGG CAAAAAGGTA 
ATGGGGCCCT CTCCCCGGCT GTACACGGAG GCACTGCAGG AGAAAAAACA GAGTGGCTTC 
CTGGCCCAGA AGTTCAAGCA GTACAAGCGA TTTGTGGAAA ACTACCGGCG CCACATTGTG 
TGTGTTACAA TCTTCTCAGC CATCTGCATA GGCCTGTTTG CAGACCGTGC CTACTACTAT 
GGCTTTGCCT CACCACCCAC GGACATCGAA GAAACCACCT ATGTGGGCAT CATCCTGTCC 
CGGGGCACGG CGGCCAGCAT CTCCTTCATG TTCTCCTACA TCCTGCTCAC CATGTGCCGC 
AACCTCATCA CCTTCTTGCG GGAGACCTTC CTCAACCGCT ACATCCCCTT TGATGCCGCT 
GTGGACTTCC ATCGCTGGAT TGCTATGGCT GCAGTTGTCC TAGCTGTTCT GCACAGTGCT 
GGACATGCAG TCAATGTGTA CATTTTCTCA GTCAGTCCCC TCAGCCTGAT GGCCTGCGTC 
TTCCCTAACG TCTTTGTGAA TGACGGGTCC AAGTTTCCCC CAAAGTACTA CTGGTGGTTC 
TTTGAGACAG TTCCAGGTAT GACAGGAGTC CTCCTGCTCC TGGTCCTGGC CATCATGTAC 
GTCTTCGCCT CCCACCACTT CCGCCGCCAC AGTTTCCGGG GCTTCTGGCT GACCCACCAC 
CTCTATGTTG TGCTTTATGT CCTGATCATC ATCCATGGCA GCTATGCCCT CATCCAATTA 
CCCAGCTTCC ACATCTACTT CCTGGTCCCA GCAATTATCT ATGGAGGGGA CAAGCTAGTG 
AGCCTGAGCC GGAAGAAGGT GGAGATCAGT GTGGTGAAGG CGGAGCTGCT GCCTTCAGGG 
GTGACCTACT TGCAGTTCCA GAGACCCAAG ACATTTGAGT ACAAATCAGG GCAGTGGGTG 
CGAATCGCGT GCCTGGATCT GGGTACCAAT GAGTATCACC CCTTCACGCT GACCTCTGCA 
CCCCATGAGG ACACACTCAG CCTGCACATC AGGGCTGTGG GACCTTGGAC TACTCGCCTC 
AGAGAGATCT ACTCACCCCC AGTGGGTGGC ACCTGTGCCA GATACCCAAA GCTGTACCTC 
GATGGACCAT TTGGAGAGGG CCATCAGGAG TGGCATAAGT TTGAGGTGTC AGTGCTGGTA 
GGAGGGGGCA TTGGAGTCAC CCCCTTTGCC TCCATCCTCA AAGACCTGGT CTTCAAATCG 
TCCATGGGCA GCCAGATGCT CTGTAAGAAG ATCTACTTCA TCTGGGTGAC AAGGACTCAG 
AGGCAGTTTG AGTGGCTGGC TGACATCATC CGGGAGGTGG AGGAGAATGA CTGCCAGGAC 
CTGGTGTCTG TGCACATCTA CATTACTCAG CTGGCTGAGA AGTTCGACCT CAGGACCACC 
ATGCTGTACA TCTGTGAGAG GCACTTCCAG AAGGCGCTGA ACAGGAGTTT GTTCACGGGC 
CTGCGTTCCA TCACCCACTT TGGTCGCCCT CCCTTTGAGC TCTTCTTCAA CTCTCTACAG 
GAAGTCCATC CACAGGTACG TAAGATTGGA GTCTTCAGCT GTGGTCCTCC AGGGATGACC 
AAGAATGTGG AGAAGGCCTG CCAGCTCATC AACAGGCAGG ACCGGGCCCA CTTTGTGCAT 
CATTATGAGA ACTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001349684.1
CDS	63..4700
Translation	MLPTSPKTLVLLGALLTGPLGPAGGQDAPSLPWEVQRYDGWFNNLKYHQRGAAGSRLRRLIPANYADGVYQALEEPLLPNPRRLSDAVAKGKAGLPSVHNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDHNTGQSPSNPRDQSNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQSSLLMWMAPDPSTGRGGPQGVYAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPHWGDEELFQHARKRVIATYQNIALYQWLPSFLQKTPPEYSGYRPFMDPSISPEFVVASEQFLSTMVPPGVYMRNSSCHFRKFPKEGSDSSPALRVCNSYWIRENPNLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPERFSRTDYVASSIQRGRDMGLPSYSQALLALGLEPPKNWSALNPQVEPQVLEATAALYNQDLSQLELLLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPRQLTTDGLPQCAPVTVIDYFEGSGAGYGVTLVAVCCFPLVSLIVAGVVAHFRNREHKMLLKKGKESLKKQPASDGVPAMEWPGPKEKSYPVTLQLLPDRSLQVLDKRFTVLRTIQLQSPQQVNLILSSNSGRRTLLLKIPKEYDLVLMFNSEEDRGAFVRLLQDLCICCTPGLHIAEVDEKELLRKAVTKQQRAGILEIFFRQLFAQVLDINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYISFREFLDILVVFMKGSSEDKSRLMFTMYDLDGNGFLSKDEFFTMMRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTKDIFKQSSACRVSFINRTPGNSSCPPETALSDMETPELGSTGLKKRFGKKVMGPSPRLYTEALQEKKQSGFLAQKFKQYKRFVENYRRHIVCVTIFSAICIGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRWIAMAAVVLAVLHSAGHAVNVYIFSVSPLSLMACVFPNVFVNDGSKFPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYVLIIIHGSYALIQLPSFHIYFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPKTFEYKSGQWVRIACLDLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPVGGTCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGSQMLCKKIYFIWVTRTQRQFEWLADIIREVEENDCQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKALNRSLFTGLRSITHFGRPPFELFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRAHFVHHYENF

Target ORF information:

RefSeq Version	NM_001362755.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual oxidase 2 (Duox2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001362755.1

ORF Insert Sequence:

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGTTCCTGCC CCCCAGAAAC GGCACTCTCT 
GACATGGAAA CCCCAGAACT GGGAAGTACT GGCCTAAAGA AGAGGTTTGG CAAAAAGGTA 
ATGGGGCCCT CTCCCCGGCT GTACACGGAG GCACTGCAGG AGAAAAAACA GAGTGGCTTC 
CTGGCCCAGA AGTTCAAGCA GTACAAGCGA TTTGTGGAAA ACTACCGGCG CCACATTGTG 
TGTGTTACAA TCTTCTCAGC CATCTGCATA GGCCTGTTTG CAGACCGTGC CTACTACTAT 
GGCTTTGCCT CACCACCCAC GGACATCGAA GAAACCACCT ATGTGGGCAT CATCCTGTCC 
CGGGGCACGG CGGCCAGCAT CTCCTTCATG TTCTCCTACA TCCTGCTCAC CATGTGCCGC 
AACCTCATCA CCTTCTTGCG GGAGACCTTC CTCAACCGCT ACATCCCCTT TGATGCCGCT 
GTGGACTTCC ATCGCTGGAT TGCTATGGCT GCAGTTGTCC TAGCTGTTCT GCACAGTGCT 
GGACATGCAG TCAATGTGTA CATTTTCTCA GTCAGTCCCC TCAGCCTGAT GGCCTGCGTC 
TTCCCTAACG TCTTTGTGAA TGACGGGTCC AAGTTTCCCC CAAAGTACTA CTGGTGGTTC 
TTTGAGACAG TTCCAGGTAT GACAGGAGTC CTCCTGCTCC TGGTCCTGGC CATCATGTAC 
GTCTTCGCCT CCCACCACTT CCGCCGCCAC AGTTTCCGGG GCTTCTGGCT GACCCACCAC 
CTCTATGTTG TGCTTTATGT CCTGATCATC ATCCATGGCA GCTATGCCCT CATCCAATTA 
CCCAGCTTCC ACATCTACTT CCTGGTCCCA GCAATTATCT ATGGAGGGGA CAAGCTAGTG 
AGCCTGAGCC GGAAGAAGGT GGAGATCAGT GTGGTGAAGG CGGAGCTGCT GCCTTCAGGG 
GTGACCTACT TGCAGTTCCA GAGACCCAAG ACATTTGAGT ACAAATCAGG GCAGTGGGTG 
CGAATCGCGT GCCTGGATCT GGGTACCAAT GAGTATCACC CCTTCACGCT GACCTCTGCA 
CCCCATGAGG ACACACTCAG CCTGCACATC AGGGCTGTGG GACCTTGGAC TACTCGCCTC 
AGAGAGATCT ACTCACCCCC AGTGGGTGGC ACCTGTGCCA GATACCCAAA GCTGTACCTC 
GATGGACCAT TTGGAGAGGG CCATCAGGAG TGGCATAAGT TTGAGGTGTC AGTGCTGGTA 
GGAGGGGGCA TTGGAGTCAC CCCCTTTGCC TCCATCCTCA AAGACCTGGT CTTCAAATCG 
TCCATGGGCA GCCAGATGCT CTGTAAGAAG ATCTACTTCA TCTGGGTGAC AAGGACTCAG 
AGGCAGTTTG AGTGGCTGGC TGACATCATC CGGGAGGTGG AGGAGAATGA CTGCCAGGAC 
CTGGTGTCTG TGCACATCTA CATTACTCAG CTGGCTGAGA AGTTCGACCT CAGGACCACC 
ATGCTGTACA TCTGTGAGAG GCACTTCCAG AAGGCGCTGA ACAGGAGTTT GTTCACGGGC 
CTGCGTTCCA TCACCCACTT TGGTCGCCCT CCCTTTGAGC TCTTCTTCAA CTCTCTACAG 
GAAGTCCATC CACAGGTACG TAAGATTGGA GTCTTCAGCT GTGGTCCTCC AGGGATGACC 
AAGAATGTGG AGAAGGCCTG CCAGCTCATC AACAGGCAGG ACCGGGCCCA CTTTGTGCAT 
CATTATGAGA ACTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Duox2 ( XM_006499110.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499173.1 Mus musculus dual oxidase 2 (Duox2), transcript variant X1, mRNA.

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CloneID	OMu30225
Clone ID Related Accession (Same CDS sequence)	NM_001362755.1 , XM_006499110.2 , XM_006499110.3
Accession Version	XM_006499110.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1466438400000
Organism	Mus musculus(house mouse)
Product	dual oxidase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006499110.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGTTCCTGCC CCCCAGAAAC GGCACTCTCT 
GACATGGAAA CCCCAGAACT GGGAAGTACT GGCCTAAAGA AGAGGTTTGG CAAAAAGGTA 
ATGGGGCCCT CTCCCCGGCT GTACACGGAG GCACTGCAGG AGAAAAAACA GAGTGGCTTC 
CTGGCCCAGA AGTTCAAGCA GTACAAGCGA TTTGTGGAAA ACTACCGGCG CCACATTGTG 
TGTGTTACAA TCTTCTCAGC CATCTGCATA GGCCTGTTTG CAGACCGTGC CTACTACTAT 
GGCTTTGCCT CACCACCCAC GGACATCGAA GAAACCACCT ATGTGGGCAT CATCCTGTCC 
CGGGGCACGG CGGCCAGCAT CTCCTTCATG TTCTCCTACA TCCTGCTCAC CATGTGCCGC 
AACCTCATCA CCTTCTTGCG GGAGACCTTC CTCAACCGCT ACATCCCCTT TGATGCCGCT 
GTGGACTTCC ATCGCTGGAT TGCTATGGCT GCAGTTGTCC TAGCTGTTCT GCACAGTGCT 
GGACATGCAG TCAATGTGTA CATTTTCTCA GTCAGTCCCC TCAGCCTGAT GGCCTGCGTC 
TTCCCTAACG TCTTTGTGAA TGACGGGTCC AAGTTTCCCC CAAAGTACTA CTGGTGGTTC 
TTTGAGACAG TTCCAGGTAT GACAGGAGTC CTCCTGCTCC TGGTCCTGGC CATCATGTAC 
GTCTTCGCCT CCCACCACTT CCGCCGCCAC AGTTTCCGGG GCTTCTGGCT GACCCACCAC 
CTCTATGTTG TGCTTTATGT CCTGATCATC ATCCATGGCA GCTATGCCCT CATCCAATTA 
CCCAGCTTCC ACATCTACTT CCTGGTCCCA GCAATTATCT ATGGAGGGGA CAAGCTAGTG 
AGCCTGAGCC GGAAGAAGGT GGAGATCAGT GTGGTGAAGG CGGAGCTGCT GCCTTCAGGG 
GTGACCTACT TGCAGTTCCA GAGACCCAAG ACATTTGAGT ACAAATCAGG GCAGTGGGTG 
CGAATCGCGT GCCTGGATCT GGGTACCAAT GAGTATCACC CCTTCACGCT GACCTCTGCA 
CCCCATGAGG ACACACTCAG CCTGCACATC AGGGCTGTGG GACCTTGGAC TACTCGCCTC 
AGAGAGATCT ACTCACCCCC AGTGGGTGGC ACCTGTGCCA GATACCCAAA GCTGTACCTC 
GATGGACCAT TTGGAGAGGG CCATCAGGAG TGGCATAAGT TTGAGGTGTC AGTGCTGGTA 
GGAGGGGGCA TTGGAGTCAC CCCCTTTGCC TCCATCCTCA AAGACCTGGT CTTCAAATCG 
TCCATGGGCA GCCAGATGCT CTGTAAGAAG ATCTACTTCA TCTGGGTGAC AAGGACTCAG 
AGGCAGTTTG AGTGGCTGGC TGACATCATC CGGGAGGTGG AGGAGAATGA CTGCCAGGAC 
CTGGTGTCTG TGCACATCTA CATTACTCAG CTGGCTGAGA AGTTCGACCT CAGGACCACC 
ATGCTGTACA TCTGTGAGAG GCACTTCCAG AAGGCGCTGA ACAGGAGTTT GTTCACGGGC 
CTGCGTTCCA TCACCCACTT TGGTCGCCCT CCCTTTGAGC TCTTCTTCAA CTCTCTACAG 
GAAGTCCATC CACAGGTACG TAAGATTGGA GTCTTCAGCT GTGGTCCTCC AGGGATGACC 
AAGAATGTGG AGAAGGCCTG CCAGCTCATC AACAGGCAGG ACCGGGCCCA CTTTGTGCAT 
CATTATGAGA ACTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499173.1
CDS	255..4892
Translation	MLPTSPKTLVLLGALLTGPLGPAGGQDAPSLPWEVQRYDGWFNNLKYHQRGAAGSRLRRLIPANYADGVYQALEEPLLPNPRRLSDAVAKGKAGLPSVHNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDHNTGQSPSNPRDQSNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQSSLLMWMAPDPSTGRGGPQGVYAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPHWGDEELFQHARKRVIATYQNIALYQWLPSFLQKTPPEYSGYRPFMDPSISPEFVVASEQFLSTMVPPGVYMRNSSCHFRKFPKEGSDSSPALRVCNSYWIRENPNLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPERFSRTDYVASSIQRGRDMGLPSYSQALLALGLEPPKNWSALNPQVEPQVLEATAALYNQDLSQLELLLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPRQLTTDGLPQCAPVTVIDYFEGSGAGYGVTLVAVCCFPLVSLIVAGVVAHFRNREHKMLLKKGKESLKKQPASDGVPAMEWPGPKEKSYPVTLQLLPDRSLQVLDKRFTVLRTIQLQSPQQVNLILSSNSGRRTLLLKIPKEYDLVLMFNSEEDRGAFVRLLQDLCICCTPGLHIAEVDEKELLRKAVTKQQRAGILEIFFRQLFAQVLDINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYISFREFLDILVVFMKGSSEDKSRLMFTMYDLDGNGFLSKDEFFTMMRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTKDIFKQSSACRVSFINRTPGNSSCPPETALSDMETPELGSTGLKKRFGKKVMGPSPRLYTEALQEKKQSGFLAQKFKQYKRFVENYRRHIVCVTIFSAICIGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRWIAMAAVVLAVLHSAGHAVNVYIFSVSPLSLMACVFPNVFVNDGSKFPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYVLIIIHGSYALIQLPSFHIYFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPKTFEYKSGQWVRIACLDLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPVGGTCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGSQMLCKKIYFIWVTRTQRQFEWLADIIREVEENDCQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKALNRSLFTGLRSITHFGRPPFELFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRAHFVHHYENF

Target ORF information:

RefSeq Version	XM_006499110.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual oxidase 2 (Duox2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499110.2

ORF Insert Sequence:

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGTTCCTGCC CCCCAGAAAC GGCACTCTCT 
GACATGGAAA CCCCAGAACT GGGAAGTACT GGCCTAAAGA AGAGGTTTGG CAAAAAGGTA 
ATGGGGCCCT CTCCCCGGCT GTACACGGAG GCACTGCAGG AGAAAAAACA GAGTGGCTTC 
CTGGCCCAGA AGTTCAAGCA GTACAAGCGA TTTGTGGAAA ACTACCGGCG CCACATTGTG 
TGTGTTACAA TCTTCTCAGC CATCTGCATA GGCCTGTTTG CAGACCGTGC CTACTACTAT 
GGCTTTGCCT CACCACCCAC GGACATCGAA GAAACCACCT ATGTGGGCAT CATCCTGTCC 
CGGGGCACGG CGGCCAGCAT CTCCTTCATG TTCTCCTACA TCCTGCTCAC CATGTGCCGC 
AACCTCATCA CCTTCTTGCG GGAGACCTTC CTCAACCGCT ACATCCCCTT TGATGCCGCT 
GTGGACTTCC ATCGCTGGAT TGCTATGGCT GCAGTTGTCC TAGCTGTTCT GCACAGTGCT 
GGACATGCAG TCAATGTGTA CATTTTCTCA GTCAGTCCCC TCAGCCTGAT GGCCTGCGTC 
TTCCCTAACG TCTTTGTGAA TGACGGGTCC AAGTTTCCCC CAAAGTACTA CTGGTGGTTC 
TTTGAGACAG TTCCAGGTAT GACAGGAGTC CTCCTGCTCC TGGTCCTGGC CATCATGTAC 
GTCTTCGCCT CCCACCACTT CCGCCGCCAC AGTTTCCGGG GCTTCTGGCT GACCCACCAC 
CTCTATGTTG TGCTTTATGT CCTGATCATC ATCCATGGCA GCTATGCCCT CATCCAATTA 
CCCAGCTTCC ACATCTACTT CCTGGTCCCA GCAATTATCT ATGGAGGGGA CAAGCTAGTG 
AGCCTGAGCC GGAAGAAGGT GGAGATCAGT GTGGTGAAGG CGGAGCTGCT GCCTTCAGGG 
GTGACCTACT TGCAGTTCCA GAGACCCAAG ACATTTGAGT ACAAATCAGG GCAGTGGGTG 
CGAATCGCGT GCCTGGATCT GGGTACCAAT GAGTATCACC CCTTCACGCT GACCTCTGCA 
CCCCATGAGG ACACACTCAG CCTGCACATC AGGGCTGTGG GACCTTGGAC TACTCGCCTC 
AGAGAGATCT ACTCACCCCC AGTGGGTGGC ACCTGTGCCA GATACCCAAA GCTGTACCTC 
GATGGACCAT TTGGAGAGGG CCATCAGGAG TGGCATAAGT TTGAGGTGTC AGTGCTGGTA 
GGAGGGGGCA TTGGAGTCAC CCCCTTTGCC TCCATCCTCA AAGACCTGGT CTTCAAATCG 
TCCATGGGCA GCCAGATGCT CTGTAAGAAG ATCTACTTCA TCTGGGTGAC AAGGACTCAG 
AGGCAGTTTG AGTGGCTGGC TGACATCATC CGGGAGGTGG AGGAGAATGA CTGCCAGGAC 
CTGGTGTCTG TGCACATCTA CATTACTCAG CTGGCTGAGA AGTTCGACCT CAGGACCACC 
ATGCTGTACA TCTGTGAGAG GCACTTCCAG AAGGCGCTGA ACAGGAGTTT GTTCACGGGC 
CTGCGTTCCA TCACCCACTT TGGTCGCCCT CCCTTTGAGC TCTTCTTCAA CTCTCTACAG 
GAAGTCCATC CACAGGTACG TAAGATTGGA GTCTTCAGCT GTGGTCCTCC AGGGATGACC 
AAGAATGTGG AGAAGGCCTG CCAGCTCATC AACAGGCAGG ACCGGGCCCA CTTTGTGCAT 
CATTATGAGA ACTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Duox2 ( XM_006499110.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499173.1 Mus musculus dual oxidase 2 (Duox2), transcript variant X1, mRNA.

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CloneID	OMu30225
Clone ID Related Accession (Same CDS sequence)	NM_001362755.1 , XM_006499110.2 , XM_006499110.3
Accession Version	XM_006499110.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565107200000
Organism	Mus musculus(house mouse)
Product	dual oxidase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006499110.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGTTCCTGCC CCCCAGAAAC GGCACTCTCT 
GACATGGAAA CCCCAGAACT GGGAAGTACT GGCCTAAAGA AGAGGTTTGG CAAAAAGGTA 
ATGGGGCCCT CTCCCCGGCT GTACACGGAG GCACTGCAGG AGAAAAAACA GAGTGGCTTC 
CTGGCCCAGA AGTTCAAGCA GTACAAGCGA TTTGTGGAAA ACTACCGGCG CCACATTGTG 
TGTGTTACAA TCTTCTCAGC CATCTGCATA GGCCTGTTTG CAGACCGTGC CTACTACTAT 
GGCTTTGCCT CACCACCCAC GGACATCGAA GAAACCACCT ATGTGGGCAT CATCCTGTCC 
CGGGGCACGG CGGCCAGCAT CTCCTTCATG TTCTCCTACA TCCTGCTCAC CATGTGCCGC 
AACCTCATCA CCTTCTTGCG GGAGACCTTC CTCAACCGCT ACATCCCCTT TGATGCCGCT 
GTGGACTTCC ATCGCTGGAT TGCTATGGCT GCAGTTGTCC TAGCTGTTCT GCACAGTGCT 
GGACATGCAG TCAATGTGTA CATTTTCTCA GTCAGTCCCC TCAGCCTGAT GGCCTGCGTC 
TTCCCTAACG TCTTTGTGAA TGACGGGTCC AAGTTTCCCC CAAAGTACTA CTGGTGGTTC 
TTTGAGACAG TTCCAGGTAT GACAGGAGTC CTCCTGCTCC TGGTCCTGGC CATCATGTAC 
GTCTTCGCCT CCCACCACTT CCGCCGCCAC AGTTTCCGGG GCTTCTGGCT GACCCACCAC 
CTCTATGTTG TGCTTTATGT CCTGATCATC ATCCATGGCA GCTATGCCCT CATCCAATTA 
CCCAGCTTCC ACATCTACTT CCTGGTCCCA GCAATTATCT ATGGAGGGGA CAAGCTAGTG 
AGCCTGAGCC GGAAGAAGGT GGAGATCAGT GTGGTGAAGG CGGAGCTGCT GCCTTCAGGG 
GTGACCTACT TGCAGTTCCA GAGACCCAAG ACATTTGAGT ACAAATCAGG GCAGTGGGTG 
CGAATCGCGT GCCTGGATCT GGGTACCAAT GAGTATCACC CCTTCACGCT GACCTCTGCA 
CCCCATGAGG ACACACTCAG CCTGCACATC AGGGCTGTGG GACCTTGGAC TACTCGCCTC 
AGAGAGATCT ACTCACCCCC AGTGGGTGGC ACCTGTGCCA GATACCCAAA GCTGTACCTC 
GATGGACCAT TTGGAGAGGG CCATCAGGAG TGGCATAAGT TTGAGGTGTC AGTGCTGGTA 
GGAGGGGGCA TTGGAGTCAC CCCCTTTGCC TCCATCCTCA AAGACCTGGT CTTCAAATCG 
TCCATGGGCA GCCAGATGCT CTGTAAGAAG ATCTACTTCA TCTGGGTGAC AAGGACTCAG 
AGGCAGTTTG AGTGGCTGGC TGACATCATC CGGGAGGTGG AGGAGAATGA CTGCCAGGAC 
CTGGTGTCTG TGCACATCTA CATTACTCAG CTGGCTGAGA AGTTCGACCT CAGGACCACC 
ATGCTGTACA TCTGTGAGAG GCACTTCCAG AAGGCGCTGA ACAGGAGTTT GTTCACGGGC 
CTGCGTTCCA TCACCCACTT TGGTCGCCCT CCCTTTGAGC TCTTCTTCAA CTCTCTACAG 
GAAGTCCATC CACAGGTACG TAAGATTGGA GTCTTCAGCT GTGGTCCTCC AGGGATGACC 
AAGAATGTGG AGAAGGCCTG CCAGCTCATC AACAGGCAGG ACCGGGCCCA CTTTGTGCAT 
CATTATGAGA ACTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499173.1
CDS	253..4890
Translation	MLPTSPKTLVLLGALLTGPLGPAGGQDAPSLPWEVQRYDGWFNNLKYHQRGAAGSRLRRLIPANYADGVYQALEEPLLPNPRRLSDAVAKGKAGLPSVHNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDHNTGQSPSNPRDQSNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQSSLLMWMAPDPSTGRGGPQGVYAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPHWGDEELFQHARKRVIATYQNIALYQWLPSFLQKTPPEYSGYRPFMDPSISPEFVVASEQFLSTMVPPGVYMRNSSCHFRKFPKEGSDSSPALRVCNSYWIRENPNLKTAQDVDQLLLGMASQISELEDRIVIEDLRDYWPGPERFSRTDYVASSIQRGRDMGLPSYSQALLALGLEPPKNWSALNPQVEPQVLEATAALYNQDLSQLELLLGGLLESHGDPGPLFSNIILDQFVRLRDGDRYWFENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPRQLTTDGLPQCAPVTVIDYFEGSGAGYGVTLVAVCCFPLVSLIVAGVVAHFRNREHKMLLKKGKESLKKQPASDGVPAMEWPGPKEKSYPVTLQLLPDRSLQVLDKRFTVLRTIQLQSPQQVNLILSSNSGRRTLLLKIPKEYDLVLMFNSEEDRGAFVRLLQDLCICCTPGLHIAEVDEKELLRKAVTKQQRAGILEIFFRQLFAQVLDINQADAGTLPLDSSQQVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYISFREFLDILVVFMKGSSEDKSRLMFTMYDLDGNGFLSKDEFFTMMRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGGAGGTKDIFKQSSACRVSFINRTPGNSSCPPETALSDMETPELGSTGLKKRFGKKVMGPSPRLYTEALQEKKQSGFLAQKFKQYKRFVENYRRHIVCVTIFSAICIGLFADRAYYYGFASPPTDIEETTYVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRWIAMAAVVLAVLHSAGHAVNVYIFSVSPLSLMACVFPNVFVNDGSKFPPKYYWWFFETVPGMTGVLLLLVLAIMYVFASHHFRRHSFRGFWLTHHLYVVLYVLIIIHGSYALIQLPSFHIYFLVPAIIYGGDKLVSLSRKKVEISVVKAELLPSGVTYLQFQRPKTFEYKSGQWVRIACLDLGTNEYHPFTLTSAPHEDTLSLHIRAVGPWTTRLREIYSPPVGGTCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFKSSMGSQMLCKKIYFIWVTRTQRQFEWLADIIREVEENDCQDLVSVHIYITQLAEKFDLRTTMLYICERHFQKALNRSLFTGLRSITHFGRPPFELFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQDRAHFVHHYENF

Target ORF information:

RefSeq Version	XM_006499110.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dual oxidase 2 (Duox2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499110.3

ORF Insert Sequence:

ATGCTTCCAA CAAGTCCCAA GACTCTAGTT CTCCTGGGCG CTCTGCTGAC TGGACCCCTG 
GGCCCAGCAG GTGGCCAGGA CGCACCCTCA CTGCCCTGGG AAGTGCAGCG CTACGACGGC 
TGGTTTAATA ATCTGAAGTA CCACCAGCGC GGTGCGGCTG GCTCGCGGCT GCGTCGCCTA 
ATACCGGCTA ATTATGCTGA CGGTGTTTAT CAGGCTCTGG AAGAGCCGCT ACTGCCCAAC 
CCTCGCCGGC TAAGCGATGC TGTCGCTAAG GGCAAAGCAG GGCTGCCCTC GGTCCACAAC 
CGCACAGTGC TGGGGGTCTT CTTTGGCTAC CACGTGCTCT CAGACCTGGT GAGTGTGGAA 
ACACCAGGCT GCCCCGCAGA GTTCCTCAAC ATTTACATCC CACGTGGGGA CCCGGTGTTC 
GACCCTGACA AGCGCGGGAA CGTGGTGCTG CCCTTTCAAA GGAGCCGCTG GGACCACAAC 
ACTGGACAGA GCCCCAGCAA CCCCCGGGAC CAGAGCAACC AGGTGACCGG CTGGCTAGAT 
GGCAGCGCCA TCTATGGCTC CTCTCATTCC TGGAGTGACA CTCTGAGGAG CTTCTCTGGA 
GGACAGCTGG CTTCTGGGCC TGACCCTGCT TTCCCGCGGA ACTCCCAGAG CTCTCTGCTC 
ATGTGGATGG CGCCGGACCC CTCCACGGGG CGGGGCGGGC CACAAGGGGT GTATGCCTTT 
GGGGCCCAGC GCGGGAACAG GGAGCCCTTT CTGCAGGCTC TGGGCTTGTT GTGGTTTCGC 
TACCACAACC TGTGTGCCAG GAAGCTGGCG CAGGAGCACC CGCACTGGGG GGATGAGGAA 
CTGTTCCAGC ATGCTCGCAA GAGGGTCATT GCCACCTACC AGAACATTGC TCTATACCAA 
TGGCTGCCCA GCTTCCTGCA GAAAACTCCT CCAGAGTATT CAGGGTACCG CCCTTTCATG 
GACCCCAGCA TCTCCCCGGA GTTCGTGGTG GCCTCTGAGC AGTTCCTCTC TACTATGGTG 
CCCCCTGGGG TCTACATGAG AAACTCCAGC TGTCATTTCC GGAAATTCCC GAAGGAAGGT 
TCAGACAGCT CTCCAGCTCT CAGAGTCTGC AACAGCTACT GGATTCGGGA GAACCCCAAT 
CTGAAGACTG CTCAAGATGT GGATCAGTTG CTGCTGGGAA TGGCTTCCCA GATCTCAGAG 
CTGGAGGACA GGATAGTGAT TGAAGACCTG AGAGATTACT GGCCTGGCCC AGAGAGATTC 
TCTCGCACAG ACTACGTGGC TAGCAGTATC CAGCGTGGCC GAGATATGGG GCTCCCCAGT 
TATAGCCAGG CTCTGCTGGC CTTGGGACTG GAGCCTCCTA AGAACTGGAG TGCTCTCAAC 
CCCCAAGTAG AACCCCAGGT GCTGGAGGCC ACAGCTGCTC TGTACAACCA GGACCTGTCC 
CAGTTGGAAC TACTCCTGGG TGGACTCCTG GAGAGCCATG GGGACCCTGG ACCTCTATTC 
AGCAACATCA TTCTTGACCA GTTTGTGAGG CTCCGGGATG GTGATCGCTA CTGGTTTGAG 
AACACTAGGA ATGGGCTGTT CTCCAAAGAG GAGATTGCAG AAATCAGAAA CACCACCTTG 
CGGGATGTAC TGGTAGCTGT CTCCAATGTG GACCCCAGTG CCTTGCAACC CAACGTTTTC 
TTCTGGCAGG AAGGTGCACC CTGCCCACAG CCTCGGCAAC TCACAACGGA CGGCTTGCCC 
CAGTGTGCGC CTGTTACTGT GATTGACTAC TTTGAGGGCA GTGGTGCTGG CTATGGTGTC 
ACGCTTGTAG CTGTCTGCTG CTTTCCATTA GTGAGTCTGA TTGTCGCTGG GGTGGTGGCT 
CATTTCCGGA ACCGAGAACA CAAGATGCTA CTAAAGAAAG GCAAAGAGAG TCTGAAGAAA 
CAACCAGCCA GTGATGGGGT ACCAGCAATG GAGTGGCCGG GCCCCAAGGA GAAGAGCTAT 
CCAGTCACTC TCCAGTTGCT TCCAGACAGA AGTCTGCAGG TCCTTGACAA ACGGTTCACT 
GTGCTCCGGA CCATCCAACT GCAGTCCCCA CAGCAGGTTA ACCTCATCCT GTCCAGCAAC 
AGTGGACGTC GCACCCTGCT GCTCAAGATC CCCAAGGAGT ATGACCTGGT GCTGATGTTT 
AACTCTGAAG AGGACCGGGG TGCCTTCGTG CGGCTGTTGC AAGACCTCTG TATCTGCTGC 
ACTCCCGGCC TCCACATAGC TGAGGTGGAT GAGAAGGAGC TATTGAGAAA GGCTGTGACC 
AAGCAGCAAC GGGCAGGCAT CTTGGAGATC TTCTTCAGAC AGCTTTTTGC TCAGGTGCTG 
GACATCAACC AGGCTGATGC AGGGACTCTG CCCCTGGACT CATCCCAGCA AGTGCGTGAG 
GCTCTGACCT GTGAGCTGAG CAGAGCTGAG TTTGCTGACT CCCTAGGCCT CAAGCCCCAG 
GACATGTTTG TGGAGTCCAT GTTTTCTCTG GCTGACAAGG ATGGCAATGG CTACATATCC 
TTCCGGGAGT TCCTGGACAT CCTGGTGGTC TTCATGAAAG GCTCCTCAGA GGATAAGTCC 
CGCCTGATGT TTACCATGTA TGACCTGGAT GGGAATGGCT TCCTCTCCAA GGACGAGTTC 
TTCACCATGA TGCGGTCCTT CATTGAGATC TCCAACAACT GCCTGTCCAA GGCCCAGCTG 
GCTGAGGTGG TTGAGTCTAT GTTCCGGGAG TCTGGGTTCC AGGACAAGGA GGAGCTGACC 
TGGGAGGACT TCCACTTCAT GCTGCGGGAC CACGACAGTG ATCTCCGATT CACACAGCTC 
TGTGTCAAAG GTGGAGCTGG AGGCACCAAG GACATCTTTA AACAAAGCAG TGCCTGTCGA 
GTCTCGTTCA TCAACCGGAC TCCTGGGAAC AGTTCCTGCC CCCCAGAAAC GGCACTCTCT 
GACATGGAAA CCCCAGAACT GGGAAGTACT GGCCTAAAGA AGAGGTTTGG CAAAAAGGTA 
ATGGGGCCCT CTCCCCGGCT GTACACGGAG GCACTGCAGG AGAAAAAACA GAGTGGCTTC 
CTGGCCCAGA AGTTCAAGCA GTACAAGCGA TTTGTGGAAA ACTACCGGCG CCACATTGTG 
TGTGTTACAA TCTTCTCAGC CATCTGCATA GGCCTGTTTG CAGACCGTGC CTACTACTAT 
GGCTTTGCCT CACCACCCAC GGACATCGAA GAAACCACCT ATGTGGGCAT CATCCTGTCC 
CGGGGCACGG CGGCCAGCAT CTCCTTCATG TTCTCCTACA TCCTGCTCAC CATGTGCCGC 
AACCTCATCA CCTTCTTGCG GGAGACCTTC CTCAACCGCT ACATCCCCTT TGATGCCGCT 
GTGGACTTCC ATCGCTGGAT TGCTATGGCT GCAGTTGTCC TAGCTGTTCT GCACAGTGCT 
GGACATGCAG TCAATGTGTA CATTTTCTCA GTCAGTCCCC TCAGCCTGAT GGCCTGCGTC 
TTCCCTAACG TCTTTGTGAA TGACGGGTCC AAGTTTCCCC CAAAGTACTA CTGGTGGTTC 
TTTGAGACAG TTCCAGGTAT GACAGGAGTC CTCCTGCTCC TGGTCCTGGC CATCATGTAC 
GTCTTCGCCT CCCACCACTT CCGCCGCCAC AGTTTCCGGG GCTTCTGGCT GACCCACCAC 
CTCTATGTTG TGCTTTATGT CCTGATCATC ATCCATGGCA GCTATGCCCT CATCCAATTA 
CCCAGCTTCC ACATCTACTT CCTGGTCCCA GCAATTATCT ATGGAGGGGA CAAGCTAGTG 
AGCCTGAGCC GGAAGAAGGT GGAGATCAGT GTGGTGAAGG CGGAGCTGCT GCCTTCAGGG 
GTGACCTACT TGCAGTTCCA GAGACCCAAG ACATTTGAGT ACAAATCAGG GCAGTGGGTG 
CGAATCGCGT GCCTGGATCT GGGTACCAAT GAGTATCACC CCTTCACGCT GACCTCTGCA 
CCCCATGAGG ACACACTCAG CCTGCACATC AGGGCTGTGG GACCTTGGAC TACTCGCCTC 
AGAGAGATCT ACTCACCCCC AGTGGGTGGC ACCTGTGCCA GATACCCAAA GCTGTACCTC 
GATGGACCAT TTGGAGAGGG CCATCAGGAG TGGCATAAGT TTGAGGTGTC AGTGCTGGTA 
GGAGGGGGCA TTGGAGTCAC CCCCTTTGCC TCCATCCTCA AAGACCTGGT CTTCAAATCG 
TCCATGGGCA GCCAGATGCT CTGTAAGAAG ATCTACTTCA TCTGGGTGAC AAGGACTCAG 
AGGCAGTTTG AGTGGCTGGC TGACATCATC CGGGAGGTGG AGGAGAATGA CTGCCAGGAC 
CTGGTGTCTG TGCACATCTA CATTACTCAG CTGGCTGAGA AGTTCGACCT CAGGACCACC 
ATGCTGTACA TCTGTGAGAG GCACTTCCAG AAGGCGCTGA ACAGGAGTTT GTTCACGGGC 
CTGCGTTCCA TCACCCACTT TGGTCGCCCT CCCTTTGAGC TCTTCTTCAA CTCTCTACAG 
GAAGTCCATC CACAGGTACG TAAGATTGGA GTCTTCAGCT GTGGTCCTCC AGGGATGACC 
AAGAATGTGG AGAAGGCCTG CCAGCTCATC AACAGGCAGG ACCGGGCCCA CTTTGTGCAT 
CATTATGAGA ACTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CRISPR/Cas9-mediated modification of the extreme C-terminus impairs PDGF-stimulated activity of Duox2.
Biological chemistry399(5)437-446(2018 04)
Tyurin-Kuzmin PA,Karagyaur MN,Rubtsov YP,Dyikanov DT,Vasiliev PA,Vorotnikov AV

Chemiluminescence imaging of Duox2-derived hydrogen peroxide for longitudinal visualization of biological response to viral infection in nasal mucosa.
Theranostics8(7)1798-1807(2018)
Kim HJ,Seo YH,An S,Jo A,Kwon IC,Kim S

Intranasal delivery of Duox2 DNA using cationic polymer can prevent acute influenza A viral infection in vivo lung.
Applied microbiology and biotechnology102(1)105-115(2018 Jan)
Kim BJ,Cho SW,Jeon YJ,An S,Jo A,Lim JH,Kim DY,Won TB,Han DH,Rhee CS,Kim HJ

GPR43 activation enhances psoriasis-like inflammation through epidermal upregulation of IL-6 and dual oxidase 2 signaling in a murine model.
Cellular signalling3359-68(2017 05)
Nadeem A,Ahmad SF,Al-Harbi NO,El-Sherbeeny AM,Al-Harbi MM,Almukhlafi TS

Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium.
Redox biology11144-156(2017 04)
Chu FF,Esworthy RS,Doroshow JH,Grasberger H,Donko A,Leto TL,Gao Q,Shen B

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Duox2 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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