Secisbp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Secisbp2
Entrez Gene ID	79049
Full Name	SECIS binding protein 2
Synonyms	Sbp2
General protein information	Preferred Names SECIS binding protein 2 Names selenocysteine insertion sequence-binding protein 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17p14
Summary	RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008771506.2	XP_008769728.1	selenocysteine insertion sequence-binding protein 2 isoform X1
NM_024002.1	NP_076492.1	selenocysteine insertion sequence-binding protein 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SECISBP2	XP_520120.3
Rattus norvegicus (Norway rat)	Secisbp2	NP_076492.1
Homo sapiens (human)	SECISBP2	NP_076982.3
Canis lupus familiaris (dog)	SECISBP2	XP_005616013.1
Mus musculus (house mouse)	Secisbp2	NP_083555.1
Gallus gallus (chicken)	SECISBP2	XP_424425.4
Bos taurus (cattle)	SECISBP2	XP_002689905.2
Xenopus tropicalis (tropical clawed frog)	secisbp2	NP_001090731.1
Macaca mulatta (Rhesus monkey)	SECISBP2	XP_001090657.1
Danio rerio (zebrafish)	LOC101883890	XP_005165670.1

Gene Ontology
Bibliography

Related articles in PubMed

Secisbp2 is essential for embryonic development and enhances selenoprotein expression.
Seeher S, Atassi T, Mahdi Y, Carlson BA, Braun D, Wirth EK, Klein MO, Reix N, Miniard AC, Schomburg L, Hatfield DL, Driscoll DM, Schweizer U
Antioxidants & redox signaling21(6)835-49(2014 Aug)

Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice.
Seeher S, Carlson BA, Miniard AC, Wirth EK, Mahdi Y, Hatfield DL, Driscoll DM, Schweizer U
The Biochemical journal462(1)67-75(2014 Aug)

Characterization of the UGA-recoding and SECIS-binding activities of SECIS-binding protein 2.
Bubenik JL, Miniard AC, Driscoll DM
RNA biology11(11)1402-13(2014)

Identification of nucleotides and amino acids that mediate the interaction between ribosomal protein L30 and the SECIS element.
Bifano AL, Atassi T, Ferrara T, Driscoll DM
BMC molecular biology1412(2013 Jun)

The selenocysteine-specific elongation factor contains a novel and multi-functional domain.
Gonzalez-Flores JN, Gupta N, DeMong LW, Copeland PR
The Journal of biological chemistry287(46)38936-45(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Secisbp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Secisbp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06762	NM_024002.1 Latest version!	Rattus norvegicus SECIS binding protein 2 (Secisbp2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
ORa43675	XM_008771506.2 Latest version!	Rattus norvegicus SECIS binding protein 2 (Secisbp2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Secisbp2 ( NM_024002.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_076492.1 Rattus norvegicus SECIS binding protein 2 (Secisbp2), mRNA.

Price & Availability↑

CloneID	ORa06762
Clone ID Related Accession (Same CDS sequence)	NM_024002.1
Accession Version	NM_024002.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2541bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550160000000
Organism	Rattus norvegicus(Norway rat)
Product	selenocysteine insertion sequence-binding protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ251245.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ251245.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGTCGG AGCGGCCGCG GGAGCCCGAA GGCGAGGATA GCATCAAGTT GTCAGCTGAT 
GTCAAACCAT TTGTCCCTAA GTTTGCTGGG CTCAATGTGG CGTGGTCAGA GTCCTCAGAA 
GCTTGTGTCT TCCCAGGCTG TGCAGCCACT TACTATCCAT TCGTACAGGA GTCACCAGCG 
GCTGAACAAA AAATGTATCC TGAAGACATG GCTTTTGGAG CCCCTGCCTT TCCAGCACAG 
TACGTGTCTT CTGAGATAGC ACTGCATCCT TTTGCCTATC CCACTTACGC CCTCGAGTCC 
ACACAGAGTG TTTGCTCAGT GCCAACCCTG CAGTACGATT ACAGCCAAGC ACAGTGTCAC 
CCAGGCTTTC GGCCAGCAAA GCCCCGAAAT GAGCACGCAT GCCCTCCTCA GGAAGCAAAG 
TGTGTATTTA AGAAAAAATC CTCTGATGAG AGAAGAGCAT GGGAAGAGCA AAAGTCAAGC 
AACAGAAGGG CTGATGGTGC AGTGCCCTGT GAGGCGAGAC CAGCCAGAGG GTCATGCCAC 
CTGAAATCTG ATGGTTATCA CAAGCGGCCT GATCGGAAGT CCAGGATCCT TACAAAAAGT 
GCATCTACCT CTAAACCCGA ATTTGAATTT AGCAGGTTGG ACTTTCCTGA ACTGCAGAGT 
CCAAAGAACA GTAATCTGCC AGAGACACAG AAGCAGCCCA GGTGGGGGCC TCTTGGCCCT 
GCTGCCAGTA ACATGTCTCT CCTGGGAGAA GCGGGCAAGC CAGTTGCAGA TATGGTAGAG 
GGTAAAATGG TGAAGACGGA TCACACTGAT GGAGCTGTGA CTAACAATGC CGCTACCAGT 
TCCCCCTCGT GTACACGAGA GTTGTCTTGG ACACCAATGG GTTATATTGT TCGGCAGACA 
GTGTCTTCAG ACTCAGCAGC AGCGACTGAA ACTGTTAATT CCATCATAAA CCTAAAGAAG 
ACTACGTCAT CAGCTGATGC TAAAAACGTT AGCGTGACAT CTGAGGCGTT ATCTTCAGAT 
CCTTCCTTCA GCAGGGAAAA GCGTGTTCAT CCTGGTCCAA AGGCCAAAGC ATCACAAGGA 
AGTGAACTTG AACAAAACGA AAGCTCCAAA AAGAATAAGA AAAAGAAAGA AAAGTCTAAA 
TCAAGTTATG AAGTCCTGCC GGTTCAGGAG CCACCGAGGA TTGAAGATGC TGAGGAATTC 
CCCAACCTGT CAGTTGCATC TGAAAGAAGA CACAGAGGGG AATCACCAAA ACTTCAGAGT 
AAACAGCAGG CGCAGAATGA CTTTAAAACG GGTGGAAAGA AGAGCCAGGT TCCGGTGCAG 
CTGGACCTGG GGGGCATGTT GGCAGCACTG GAGAAGCAGC AGCACGCCCC GCACGCCAAG 
CCATCCTCCA GACCCGTCGT GTTCTCAGTT GGAGCAGTGC CAGTCCTTTC CAAGGATGCC 
TCCTCAGGTG AGAGGGGTCG CCGCTCTAGT CAGGTGAAGA CCCCACACAA CCCCCTGGAC 
TCCAGTGCCC CCCTAATGAA GAAGGGGAAG CAGAGGGAGA TACCTAAGGC CAAGAAGCCC 
ACCTCACTGA AGAAGATAAT TTTGAAAGAA CGGCAAGAGA GAATGCAGCA GCGACTCCAA 
GAAAGTGCTG TGAGCCCGAC TGTGGCCAGT GATGACTCAC AGGATGTGGA GAGTGGTGTT 
ACTAACCAAA TCCCCAGCCC GGACAACCCC ACAGGTCCAG AGAAGACAGA AGAACCCATG 
TCTTCTACAC CTGTGGTTGA GGGTGAGTCA GAAGAGCCAG CTGGCACAGA GTTCCAGAGG 
GACCCAGAGG CTTGCCAGCC TGCCCCTGAC AGTGCCACCT TCCCCAAGAT CCACAGCCGG 
AGGTTCCGGG ACTACTGCAG CCAGATGCTT AGTAAAGAAG TCGATGCTTG TGTCACGGGT 
CTCCTCAAGG AACTGGTGCG CTTCCAAGAC CGGATGTACC AGAAGGATCC TGTCAAGGCC 
AAGACAAAAC GCCGGCTTGT GCTGGGGCTG AGGGAGGTCC TGAAACACCT GAAGCTCAGG 
AAGCTGAAGT GTATCATCAT CTCTCCCAAC TGTGAGAAGA CACAGTCTAA AGGTGGACTG 
GACGACACAC TGCACACCAT CATCGATTGC GCCTGTGAGC AGAACATCCC CTTTGTGTTT 
GCACTCAACC GCAAGGCACT GGGGCGGAGT CTGAATAAAG CAGTTCCTGT CAGCATTGTA 
GGGATCTTCA GTTACGATGG GGCCCAGGAC CAGTTCCACA AGATGGTTGA GCTGACCATG 
GCAGCCCGTC AGGCATACAA GACCATGTTG GAGACGATGC GGCAGGAGCA GGCAGGAGAA 
CCTGGGCCTC AGACCCCTCC CAGCCCACCC ATGCAGGACC CCATCCAGTC CACCGACGAA 
GGCACCCTAG CTTCCACTGG AGAAGAGCCA CACTATATTG AGATTTGGAG AAAGCATCTG 
GAAGCGTACA GTCAGCATGC CCTGGAGCTG GAAGACTCAC TGGAGGCATC AACCTCTCAG 
ATGATGAACT TGAATTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076492.1
CDS	44..2584
Translation	MASERPREPEGEDSIKLSADVKPFVPKFAGLNVAWSESSEACVFPGCAATYYPFVQESPAAEQKMYPEDMAFGAPAFPAQYVSSEIALHPFAYPTYALESTQSVCSVPTLQYDYSQAQCHPGFRPAKPRNEHACPPQEAKCVFKKKSSDERRAWEEQKSSNRRADGAVPCEARPARGSCHLKSDGYHKRPDRKSRILTKSASTSKPEFEFSRLDFPELQSPKNSNLPETQKQPRWGPLGPAASNMSLLGEAGKPVADMVEGKMVKTDHTDGAVTNNAATSSPSCTRELSWTPMGYIVRQTVSSDSAAATETVNSIINLKKTTSSADAKNVSVTSEALSSDPSFSREKRVHPGPKAKASQGSELEQNESSKKNKKKKEKSKSSYEVLPVQEPPRIEDAEEFPNLSVASERRHRGESPKLQSKQQAQNDFKTGGKKSQVPVQLDLGGMLAALEKQQHAPHAKPSSRPVVFSVGAVPVLSKDASSGERGRRSSQVKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERMQQRLQESAVSPTVASDDSQDVESGVTNQIPSPDNPTGPEKTEEPMSSTPVVEGESEEPAGTEFQRDPEACQPAPDSATFPKIHSRRFRDYCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSKGGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQDQFHKMVELTMAARQAYKTMLETMRQEQAGEPGPQTPPSPPMQDPIQSTDEGTLASTGEEPHYIEIWRKHLEAYSQHALELEDSLEASTSQMMNLNL

Target ORF information:

RefSeq Version	NM_024002.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SECIS binding protein 2 (Secisbp2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024002.1

ORF Insert Sequence:

ATGGCGTCGG AGCGGCCGCG GGAGCCCGAA GGCGAGGATA GCATCAAGTT GTCAGCTGAT 
GTCAAACCAT TTGTCCCTAA GTTTGCTGGG CTCAATGTGG CGTGGTCAGA GTCCTCAGAA 
GCTTGTGTCT TCCCAGGCTG TGCAGCCACT TACTATCCAT TCGTACAGGA GTCACCAGCG 
GCTGAACAAA AAATGTATCC TGAAGACATG GCTTTTGGAG CCCCTGCCTT TCCAGCACAG 
TACGTGTCTT CTGAGATAGC ACTGCATCCT TTTGCCTATC CCACTTACGC CCTCGAGTCC 
ACACAGAGTG TTTGCTCAGT GCCAACCCTG CAGTACGATT ACAGCCAAGC ACAGTGTCAC 
CCAGGCTTTC GGCCAGCAAA GCCCCGAAAT GAGCACGCAT GCCCTCCTCA GGAAGCAAAG 
TGTGTATTTA AGAAAAAATC CTCTGATGAG AGAAGAGCAT GGGAAGAGCA AAAGTCAAGC 
AACAGAAGGG CTGATGGTGC AGTGCCCTGT GAGGCGAGAC CAGCCAGAGG GTCATGCCAC 
CTGAAATCTG ATGGTTATCA CAAGCGGCCT GATCGGAAGT CCAGGATCCT TACAAAAAGT 
GCATCTACCT CTAAACCCGA ATTTGAATTT AGCAGGTTGG ACTTTCCTGA ACTGCAGAGT 
CCAAAGAACA GTAATCTGCC AGAGACACAG AAGCAGCCCA GGTGGGGGCC TCTTGGCCCT 
GCTGCCAGTA ACATGTCTCT CCTGGGAGAA GCGGGCAAGC CAGTTGCAGA TATGGTAGAG 
GGTAAAATGG TGAAGACGGA TCACACTGAT GGAGCTGTGA CTAACAATGC CGCTACCAGT 
TCCCCCTCGT GTACACGAGA GTTGTCTTGG ACACCAATGG GTTATATTGT TCGGCAGACA 
GTGTCTTCAG ACTCAGCAGC AGCGACTGAA ACTGTTAATT CCATCATAAA CCTAAAGAAG 
ACTACGTCAT CAGCTGATGC TAAAAACGTT AGCGTGACAT CTGAGGCGTT ATCTTCAGAT 
CCTTCCTTCA GCAGGGAAAA GCGTGTTCAT CCTGGTCCAA AGGCCAAAGC ATCACAAGGA 
AGTGAACTTG AACAAAACGA AAGCTCCAAA AAGAATAAGA AAAAGAAAGA AAAGTCTAAA 
TCAAGTTATG AAGTCCTGCC GGTTCAGGAG CCACCGAGGA TTGAAGATGC TGAGGAATTC 
CCCAACCTGT CAGTTGCATC TGAAAGAAGA CACAGAGGGG AATCACCAAA ACTTCAGAGT 
AAACAGCAGG CGCAGAATGA CTTTAAAACG GGTGGAAAGA AGAGCCAGGT TCCGGTGCAG 
CTGGACCTGG GGGGCATGTT GGCAGCACTG GAGAAGCAGC AGCACGCCCC GCACGCCAAG 
CCATCCTCCA GACCCGTCGT GTTCTCAGTT GGAGCAGTGC CAGTCCTTTC CAAGGATGCC 
TCCTCAGGTG AGAGGGGTCG CCGCTCTAGT CAGGTGAAGA CCCCACACAA CCCCCTGGAC 
TCCAGTGCCC CCCTAATGAA GAAGGGGAAG CAGAGGGAGA TACCTAAGGC CAAGAAGCCC 
ACCTCACTGA AGAAGATAAT TTTGAAAGAA CGGCAAGAGA GAATGCAGCA GCGACTCCAA 
GAAAGTGCTG TGAGCCCGAC TGTGGCCAGT GATGACTCAC AGGATGTGGA GAGTGGTGTT 
ACTAACCAAA TCCCCAGCCC GGACAACCCC ACAGGTCCAG AGAAGACAGA AGAACCCATG 
TCTTCTACAC CTGTGGTTGA GGGTGAGTCA GAAGAGCCAG CTGGCACAGA GTTCCAGAGG 
GACCCAGAGG CTTGCCAGCC TGCCCCTGAC AGTGCCACCT TCCCCAAGAT CCACAGCCGG 
AGGTTCCGGG ACTACTGCAG CCAGATGCTT AGTAAAGAAG TCGATGCTTG TGTCACGGGT 
CTCCTCAAGG AACTGGTGCG CTTCCAAGAC CGGATGTACC AGAAGGATCC TGTCAAGGCC 
AAGACAAAAC GCCGGCTTGT GCTGGGGCTG AGGGAGGTCC TGAAACACCT GAAGCTCAGG 
AAGCTGAAGT GTATCATCAT CTCTCCCAAC TGTGAGAAGA CACAGTCTAA AGGTGGACTG 
GACGACACAC TGCACACCAT CATCGATTGC GCCTGTGAGC AGAACATCCC CTTTGTGTTT 
GCACTCAACC GCAAGGCACT GGGGCGGAGT CTGAATAAAG CAGTTCCTGT CAGCATTGTA 
GGGATCTTCA GTTACGATGG GGCCCAGGAC CAGTTCCACA AGATGGTTGA GCTGACCATG 
GCAGCCCGTC AGGCATACAA GACCATGTTG GAGACGATGC GGCAGGAGCA GGCAGGAGAA 
CCTGGGCCTC AGACCCCTCC CAGCCCACCC ATGCAGGACC CCATCCAGTC CACCGACGAA 
GGCACCCTAG CTTCCACTGG AGAAGAGCCA CACTATATTG AGATTTGGAG AAAGCATCTG 
GAAGCGTACA GTCAGCATGC CCTGGAGCTG GAAGACTCAC TGGAGGCATC AACCTCTCAG 
ATGATGAACT TGAATTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Secisbp2 ( XM_008771506.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008769728.1 Rattus norvegicus SECIS binding protein 2 (Secisbp2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43675
Clone ID Related Accession (Same CDS sequence)	XM_008771506.2
Accession Version	XM_008771506.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2544bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	selenocysteine insertion sequence-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008771506.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTCGG AGCGGCCGCG GGAGCCCGAA GGCGAGGATA GCATCAAGTT GTCAGCTGAT 
GTCAAACCAT TTGTCCCTAA GTTTGCTGGG CTCAATGTGG CGTGGTCAGA GTCCTCAGAA 
GCTTGTGTCT TCCCAGGCTG TGCAGCCACT TACTATCCAT TCGTACAGGA GTCACCAGCG 
GCTGAACAAA AAATGTATCC TGAAGACATG GCTTTTGGAG CCCCTGCCTT TCCAGCACAG 
TACGTGTCTT CTGAGATAGC ACTGCATCCT TTTGCCTATC CCACTTACGC CCTCGAGTCC 
ACACAGAGTG TTTGCTCAGT GCCAACCCTG CAGTACGATT ACAGCCAAGC ACAGTGTCAC 
CCAGGCTTTC GGCCAGCAAA GCCCCGAAAT GAGCACGCAT GCCCTCCTCA GGAAGCAAAG 
TGTGTATTTA AGAAAAAATC CTCTGATGAG AGAAGAGCAT GGGAAGAGCA AAAGTCAAGC 
AACAGAAGGG CTGATGGTGC AGTGCCCTGT GAGGCGAGAC CAGCCAGAGG GTCATGCCAC 
CTGAAATCTG ATGGTTATCA CAAGCGGCCT GATCGGAAGT CCAGGATCCT TACAAAAAGT 
GCATCTACCT CTAAACCCGA ATTTGAATTT AGCAGGTTGG ACTTTCCTGA ACTGCAGAGT 
CCAAAGAACA GTAATCTGCC AGAGACACAG AAGCAGCCCA GGTGGGGGCC TCTTGGCCCT 
GCTGCCAGTA ACATGTCTCT CCTGGGAGAA TCGGGCAAGC CAGTTGCAGA TATGGTAGAG 
GGTAAAATGG TGAAGACGGA TCACACTGAT GGAGCTGTGA CTAACAATGC CGCTACCAGT 
TCCCCCTCGT GTACACGAGC AGAGTTGTCT TGGACACCAA TGGGTTATAT TGTTCGGCAG 
ACAGTGTCTT CAGACTCAGC AGCAGCGACT GAAACTGTTA ATTCCATCAT AAACCTAAAG 
AAGACTACGT CATCAGCTGA TGCTAAAAAC GTTAGCGTGA CATCTGAGGC GTTATCTTCA 
GATCCTTCCT TCAGCAGGGA AAAGCGTGTT CATCCTGGTC CAAAGGCCAA AGCATCACAA 
GGAAGTGAAC TTGAACAAAA CGAAAGCTCC AAAAAGAATA AGAAAAAGAA AGAAAAGTCT 
AAATCAAGTT ATGAAGTCCT GCCGGTTCAG GAGCCACCGA GGATTGAAGA TGCTGAGGAA 
TTCCCCAACC TGTCAGTTGC ATCTGAAAGA AGACACAGAG GGGAATCACC AAAACTTCAG 
AGTAAACAGC AGGCGCAGAA TGACTTTAAA ACGGGTGGAA AGAAGAGCCA GGTTCCGGTG 
CAGCTGGACC TGGGGGGCAT GTTGGCAGCA CTGGAGAAGC AGCAGCACGC CCCGCACGCC 
AAGCCATCCT CCAGACCCGT CGTGTTCTCA GTTGGAGCAG TGCCAGTCCT TTCCAAGGAT 
GCCTCCTCAG GTGAGAGGGG TCGCCGCTCT AGTCAGGTGA AGACCCCACA CAACCCCCTG 
GACTCCAGTG CCCCCCTAAT GAAGAAGGGG AAGCAGAGGG AGATACCTAA GGCCAAGAAG 
CCCACCTCAC TGAAGAAGAT AATTTTGAAA GAACGGCAAG AGAGAATGCA GCAGCGACTC 
CAAGAAAGTG CTGTGAGCCC GACTGTGGCC AGTGATGACT CACAGGATGT GGAGAGTGGT 
GTTACTAACC AAATCCCCAG CCCGGACAAC CCCACAGGTC CAGAGAAGAC AGAAGAACCC 
GTGTCTTCTA CACCTGTGGT TGAGGGTGAG TCAGAAGAGC CAGCTGGCAC AGAGTTCCAG 
AGGGACCCAG AGGCTTGCCA GCCTGCCCCT GACAGTGCCA CCTTCCCCAA GATCCACAGC 
CGGAGGTTCC GGGACTACTG CAGCCAGATG CTTAGTAAAG AAGTCGATGC TTGTGTCACG 
GGTCTCCTCA AGGAACTGGT GCGCTTCCAA GACCGGATGT ACCAGAAGGA TCCTGTCAAG 
GCCAAGACAA AACGCCGGCT TGTGCTGGGG CTGAGGGAGG TCCTGAAACA CCTGAAGCTC 
AGGAAGCTGA AGTGTATCAT CATCTCTCCC AACTGTGAGA AGACACAGTC TAAAGGTGGA 
CTGGACGACA CACTGCACAC CATCATCGAT TGCGCCTGTG AGCAGAACAT CCCCTTTGTG 
TTTGCACTCA ACCGCAAGGC ACTGGGGCGG AGTCTGAATA AAGCAGTTCC TGTCAGCATT 
GTAGGGATCT TCAGTTACGA TGGGGCCCAG GACCAGTTCC ACAAGATGGT TGAGCTGACC 
ATGGCAGCCC GTCAGGCATA CAAGACCATG TTGGAGACGA TGCGGCAGGA GCAGGCAGGA 
GAACCTGGGC CTCAGACCCC TCCCAGCCCA CCCATGCAGG ACCCCATCCA GTCCACCGAC 
GAAGGCACCC TAGCTTCCAC TGGAGAAGAG CCACACTATA TTGAGATTTG GAGAAAGCAT 
CTGGAAGCGT ACAGTCAGCA TGCCCTGGAG CTGGAAGACT CACTGGAGGC ATCAACCTCT 
CAGATGATGA ACTTGAATTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008769728.1
CDS	85..2628
Translation	MASERPREPEGEDSIKLSADVKPFVPKFAGLNVAWSESSEACVFPGCAATYYPFVQESPAAEQKMYPEDMAFGAPAFPAQYVSSEIALHPFAYPTYALESTQSVCSVPTLQYDYSQAQCHPGFRPAKPRNEHACPPQEAKCVFKKKSSDERRAWEEQKSSNRRADGAVPCEARPARGSCHLKSDGYHKRPDRKSRILTKSASTSKPEFEFSRLDFPELQSPKNSNLPETQKQPRWGPLGPAASNMSLLGESGKPVADMVEGKMVKTDHTDGAVTNNAATSSPSCTRAELSWTPMGYIVRQTVSSDSAAATETVNSIINLKKTTSSADAKNVSVTSEALSSDPSFSREKRVHPGPKAKASQGSELEQNESSKKNKKKKEKSKSSYEVLPVQEPPRIEDAEEFPNLSVASERRHRGESPKLQSKQQAQNDFKTGGKKSQVPVQLDLGGMLAALEKQQHAPHAKPSSRPVVFSVGAVPVLSKDASSGERGRRSSQVKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERMQQRLQESAVSPTVASDDSQDVESGVTNQIPSPDNPTGPEKTEEPVSSTPVVEGESEEPAGTEFQRDPEACQPAPDSATFPKIHSRRFRDYCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSKGGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQDQFHKMVELTMAARQAYKTMLETMRQEQAGEPGPQTPPSPPMQDPIQSTDEGTLASTGEEPHYIEIWRKHLEAYSQHALELEDSLEASTSQMMNLNL

Target ORF information:

RefSeq Version	XM_008771506.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SECIS binding protein 2 (Secisbp2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008771506.2

ORF Insert Sequence:

ATGGCGTCGG AGCGGCCGCG GGAGCCCGAA GGCGAGGATA GCATCAAGTT GTCAGCTGAT 
GTCAAACCAT TTGTCCCTAA GTTTGCTGGG CTCAATGTGG CGTGGTCAGA GTCCTCAGAA 
GCTTGTGTCT TCCCAGGCTG TGCAGCCACT TACTATCCAT TCGTACAGGA GTCACCAGCG 
GCTGAACAAA AAATGTATCC TGAAGACATG GCTTTTGGAG CCCCTGCCTT TCCAGCACAG 
TACGTGTCTT CTGAGATAGC ACTGCATCCT TTTGCCTATC CCACTTACGC CCTCGAGTCC 
ACACAGAGTG TTTGCTCAGT GCCAACCCTG CAGTACGATT ACAGCCAAGC ACAGTGTCAC 
CCAGGCTTTC GGCCAGCAAA GCCCCGAAAT GAGCACGCAT GCCCTCCTCA GGAAGCAAAG 
TGTGTATTTA AGAAAAAATC CTCTGATGAG AGAAGAGCAT GGGAAGAGCA AAAGTCAAGC 
AACAGAAGGG CTGATGGTGC AGTGCCCTGT GAGGCGAGAC CAGCCAGAGG GTCATGCCAC 
CTGAAATCTG ATGGTTATCA CAAGCGGCCT GATCGGAAGT CCAGGATCCT TACAAAAAGT 
GCATCTACCT CTAAACCCGA ATTTGAATTT AGCAGGTTGG ACTTTCCTGA ACTGCAGAGT 
CCAAAGAACA GTAATCTGCC AGAGACACAG AAGCAGCCCA GGTGGGGGCC TCTTGGCCCT 
GCTGCCAGTA ACATGTCTCT CCTGGGAGAA TCGGGCAAGC CAGTTGCAGA TATGGTAGAG 
GGTAAAATGG TGAAGACGGA TCACACTGAT GGAGCTGTGA CTAACAATGC CGCTACCAGT 
TCCCCCTCGT GTACACGAGC AGAGTTGTCT TGGACACCAA TGGGTTATAT TGTTCGGCAG 
ACAGTGTCTT CAGACTCAGC AGCAGCGACT GAAACTGTTA ATTCCATCAT AAACCTAAAG 
AAGACTACGT CATCAGCTGA TGCTAAAAAC GTTAGCGTGA CATCTGAGGC GTTATCTTCA 
GATCCTTCCT TCAGCAGGGA AAAGCGTGTT CATCCTGGTC CAAAGGCCAA AGCATCACAA 
GGAAGTGAAC TTGAACAAAA CGAAAGCTCC AAAAAGAATA AGAAAAAGAA AGAAAAGTCT 
AAATCAAGTT ATGAAGTCCT GCCGGTTCAG GAGCCACCGA GGATTGAAGA TGCTGAGGAA 
TTCCCCAACC TGTCAGTTGC ATCTGAAAGA AGACACAGAG GGGAATCACC AAAACTTCAG 
AGTAAACAGC AGGCGCAGAA TGACTTTAAA ACGGGTGGAA AGAAGAGCCA GGTTCCGGTG 
CAGCTGGACC TGGGGGGCAT GTTGGCAGCA CTGGAGAAGC AGCAGCACGC CCCGCACGCC 
AAGCCATCCT CCAGACCCGT CGTGTTCTCA GTTGGAGCAG TGCCAGTCCT TTCCAAGGAT 
GCCTCCTCAG GTGAGAGGGG TCGCCGCTCT AGTCAGGTGA AGACCCCACA CAACCCCCTG 
GACTCCAGTG CCCCCCTAAT GAAGAAGGGG AAGCAGAGGG AGATACCTAA GGCCAAGAAG 
CCCACCTCAC TGAAGAAGAT AATTTTGAAA GAACGGCAAG AGAGAATGCA GCAGCGACTC 
CAAGAAAGTG CTGTGAGCCC GACTGTGGCC AGTGATGACT CACAGGATGT GGAGAGTGGT 
GTTACTAACC AAATCCCCAG CCCGGACAAC CCCACAGGTC CAGAGAAGAC AGAAGAACCC 
GTGTCTTCTA CACCTGTGGT TGAGGGTGAG TCAGAAGAGC CAGCTGGCAC AGAGTTCCAG 
AGGGACCCAG AGGCTTGCCA GCCTGCCCCT GACAGTGCCA CCTTCCCCAA GATCCACAGC 
CGGAGGTTCC GGGACTACTG CAGCCAGATG CTTAGTAAAG AAGTCGATGC TTGTGTCACG 
GGTCTCCTCA AGGAACTGGT GCGCTTCCAA GACCGGATGT ACCAGAAGGA TCCTGTCAAG 
GCCAAGACAA AACGCCGGCT TGTGCTGGGG CTGAGGGAGG TCCTGAAACA CCTGAAGCTC 
AGGAAGCTGA AGTGTATCAT CATCTCTCCC AACTGTGAGA AGACACAGTC TAAAGGTGGA 
CTGGACGACA CACTGCACAC CATCATCGAT TGCGCCTGTG AGCAGAACAT CCCCTTTGTG 
TTTGCACTCA ACCGCAAGGC ACTGGGGCGG AGTCTGAATA AAGCAGTTCC TGTCAGCATT 
GTAGGGATCT TCAGTTACGA TGGGGCCCAG GACCAGTTCC ACAAGATGGT TGAGCTGACC 
ATGGCAGCCC GTCAGGCATA CAAGACCATG TTGGAGACGA TGCGGCAGGA GCAGGCAGGA 
GAACCTGGGC CTCAGACCCC TCCCAGCCCA CCCATGCAGG ACCCCATCCA GTCCACCGAC 
GAAGGCACCC TAGCTTCCAC TGGAGAAGAG CCACACTATA TTGAGATTTG GAGAAAGCAT 
CTGGAAGCGT ACAGTCAGCA TGCCCTGGAG CTGGAAGACT CACTGGAGGC ATCAACCTCT 
CAGATGATGA ACTTGAATTT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Secisbp2 is essential for embryonic development and enhances selenoprotein expression.
Antioxidants & redox signaling21(6)835-49(2014 Aug)
Seeher S,Atassi T,Mahdi Y,Carlson BA,Braun D,Wirth EK,Klein MO,Reix N,Miniard AC,Schomburg L,Hatfield DL,Driscoll DM,Schweizer U

Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice.
The Biochemical journal462(1)67-75(2014 Aug)
Seeher S,Carlson BA,Miniard AC,Wirth EK,Mahdi Y,Hatfield DL,Driscoll DM,Schweizer U

Characterization of the UGA-recoding and SECIS-binding activities of SECIS-binding protein 2.
RNA biology11(11)1402-13(2014)
Bubenik JL,Miniard AC,Driscoll DM

Identification of nucleotides and amino acids that mediate the interaction between ribosomal protein L30 and the SECIS element.
BMC molecular biology1412(2013 Jun)
Bifano AL,Atassi T,Ferrara T,Driscoll DM

The selenocysteine-specific elongation factor contains a novel and multi-functional domain.
The Journal of biological chemistry287(46)38936-45(2012 Nov)
Gonzalez-Flores JN,Gupta N,DeMong LW,Copeland PR

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Secisbp2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM