Nmur2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nmur2
Entrez Gene ID	64042
Full Name	neuromedin U receptor 2
Synonyms	FM-4,Nmu2r
General protein information	Preferred Names neuromedin U receptor 2 Names neuromedin-U receptor 2 G-protein coupled receptor TGR-1 G-protein-coupled receptor FM-4 NMU-R2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q22
Summary	receptor for the Nmu neuropeptide involved in the central control of feeding [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022275.3	NP_071611.3	neuromedin-U receptor 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	NMUR2	NP_064552.3
Bos taurus (cattle)	NMUR2	NP_001030220.1
Drosophila melanogaster (fruit fly)	capaR	NP_996140.1
Caenorhabditis elegans (roundworm)	nmur-1	NP_509515.2
Mus musculus (house mouse)	Nmur2	NP_694719.2
Gallus gallus (chicken)	NMUR2	XP_425209.2
Xenopus tropicalis (tropical clawed frog)	nmur2	XP_002940961.1
Danio rerio (zebrafish)	LOC566750	XP_695127.2
Pan troglodytes (chimpanzee)	NMUR2	XP_527091.1
Rattus norvegicus (Norway rat)	Nmur2	NP_071611.3
Canis lupus familiaris (dog)	NMUR2	XP_546288.1

Gene Ontology
Bibliography

Related articles in PubMed

Incubation of feeding behavior is regulated by neuromedin U receptor 2 in the paraventricular nucleus of the hypothalamus.
McCue DL, Kasper JM, A, Hommel JD
Behavioural brain research359763-770(2019 02)

Neuromedin U receptor 2 knockdown in the paraventricular nucleus modifies behavioral responses to obesogenic high-fat food and leads to increased body weight.
Benzon CR, Johnson SB, McCue DL, Li D, Green TA, Hommel JD
Neuroscience258270-9(2014 Jan)

Ovarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2.
Lin TY, Wu FJ, Lee WY, Hsiao CL, Luo CW
American journal of physiology. Endocrinology and metabolism304(8)E800-9(2013 Apr)

Neuromedin U(2) receptor signaling mediates alteration of sleep-wake architecture in rats.
Ahnaou A, Drinkenburg WH
Neuropeptides45(2)165-74(2011 Apr)

Neuromedin U directly stimulates growth of cultured rat calvarial osteoblast-like cells acting via the NMU receptor 2 isoform.
Rucinski M, Ziolkowska A, Tyczewska M, Szyszka M, Malendowicz LK
International journal of molecular medicine22(3)363-8(2008 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nmur2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nmur2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12151	NM_022275.3 Latest version!	Rattus norvegicus neuromedin U receptor 2 (Nmur2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nmur2 ( NM_022275.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071611.3 Rattus norvegicus neuromedin U receptor 2 (Nmur2), mRNA.

Price & Availability↑

CloneID	ORa12151
Clone ID Related Accession (Same CDS sequence)	NM_022275.3
Accession Version	NM_022275.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568908800000
Organism	Rattus norvegicus(Norway rat)
Product	neuromedin-U receptor 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029623.1, AB041229.1, AF242875.1, CB556410.1 and BM384513.1. On Aug 2, 2012 this sequence version replaced NM_022275.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB041229.1, AF242875.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689601, SAMN02642720 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END##

ATGGGAAAAC TTGAAAATGC TTCCTGGATC CACGATCCTC TCATGAAGTA CTTGAACAGC 
ACAGAGGAGT ACTTGGCCCA CCTGTGTGGA CCCAAGCGCA GTGACCTATC CCTTCCGGTG 
TCTGTGGCCT ATGCGCTGAT CTTCCTGGTG GGGGTAATGG GCAATCTTCT GGTGTGCATG 
GTGATTGTCC GACATCAGAC TTTGAAGACA CCCACCAACT ACTATCTCTT CAGCTTGGCA 
GTCTCAGATC TGCTGGTCCT GCTCTTGGGG ATGCCTCTGG AAATCTACGA GATGTGGCAC 
AATTACCCTT TCCTGTTCGG GCCTGTGGGA TGCTACTTCA AGACAGCCCT CTTCGAGACT 
GTGTGCTTTG CCTCCATTCT CAGTGTCACC ACGGTTAGCG TAGAGCGCTA TGTGGCCATT 
GTCCACCCTT TCCGAGCCAA GCTGGAGAGC ACGCGGCGAC GGGCCCTCAG GATCCTCAGC 
CTAGTCTGGA GCTTCTCTGT GGTCTTTTCT TTGCCCAATA CCAGCATCCA TGGCATCAAG 
TTCCAGCACT TTCCCAACGG GTCCTCCGTA CCTGGCTCAG CCACCTGCAC AGTCACCAAA 
CCCATGTGGG TGTATAACTT GATCATCCAA GCTACCAGCT TCCTCTTCTA CATCCTCCCA 
ATGACCCTCA TCAGCGTCCT CTACTACCTC ATGGGGCTCA GGCTGAAGAG AGATGAATCC 
CTTGAGGCGA ACAAAGTGGC TGTGAATATT CACAGACCCT CTAGAAAGTC AGTCACCAAG 
ATGCTGTTTG TCTTGGTCCT CGTGTTTGCC ATCTGCTGGA CCCCCTTCCA TGTGGACCGG 
CTCTTCTTCA GCTTTGTGGA AGAGTGGACA GAGTCCCTGG CTGCTGTGTT CAACCTCATC 
CATGTGGTAT CAGGTGTCTT CTTTTATCTG AGCTCCGCGG TCAACCCCAT TATCTATAAC 
CTCCTGTCTC GGCGCTTCCG GGCGGCCTTT CGAAATGTTG TCTCCCCTAC CTGCAAATGG 
TGCCATCCCC GGCATCGGCC ACAGGGACCT CCAGCCCAGA AGATCATCTT CTTGACAGAA 
TGTCACCTCG TGGAGCTGAC AGAGGATGCA GGCCCCCAGT TCCCTGGTCA GTCATCCATC 
CACAACACCA ACCTTACCAC GGCCCCCTGT GCAGGAGAGG TACCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071611.3
CDS	127..1314
Translation	MGKLENASWIHDPLMKYLNSTEEYLAHLCGPKRSDLSLPVSVAYALIFLVGVMGNLLVCMVIVRHQTLKTPTNYYLFSLAVSDLLVLLLGMPLEIYEMWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSVERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQHFPNGSSVPGSATCTVTKPMWVYNLIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEANKVAVNIHRPSRKSVTKMLFVLVLVFAICWTPFHVDRLFFSFVEEWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAAFRNVVSPTCKWCHPRHRPQGPPAQKIIFLTECHLVELTEDAGPQFPGQSSIHNTNLTTAPCAGEVP

Target ORF information:

RefSeq Version	NM_022275.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus neuromedin U receptor 2 (Nmur2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022275.3

ORF Insert Sequence:

ATGGGAAAAC TTGAAAATGC TTCCTGGATC CACGATCCTC TCATGAAGTA CTTGAACAGC 
ACAGAGGAGT ACTTGGCCCA CCTGTGTGGA CCCAAGCGCA GTGACCTATC CCTTCCGGTG 
TCTGTGGCCT ATGCGCTGAT CTTCCTGGTG GGGGTAATGG GCAATCTTCT GGTGTGCATG 
GTGATTGTCC GACATCAGAC TTTGAAGACA CCCACCAACT ACTATCTCTT CAGCTTGGCA 
GTCTCAGATC TGCTGGTCCT GCTCTTGGGG ATGCCTCTGG AAATCTACGA GATGTGGCAC 
AATTACCCTT TCCTGTTCGG GCCTGTGGGA TGCTACTTCA AGACAGCCCT CTTCGAGACT 
GTGTGCTTTG CCTCCATTCT CAGTGTCACC ACGGTTAGCG TAGAGCGCTA TGTGGCCATT 
GTCCACCCTT TCCGAGCCAA GCTGGAGAGC ACGCGGCGAC GGGCCCTCAG GATCCTCAGC 
CTAGTCTGGA GCTTCTCTGT GGTCTTTTCT TTGCCCAATA CCAGCATCCA TGGCATCAAG 
TTCCAGCACT TTCCCAACGG GTCCTCCGTA CCTGGCTCAG CCACCTGCAC AGTCACCAAA 
CCCATGTGGG TGTATAACTT GATCATCCAA GCTACCAGCT TCCTCTTCTA CATCCTCCCA 
ATGACCCTCA TCAGCGTCCT CTACTACCTC ATGGGGCTCA GGCTGAAGAG AGATGAATCC 
CTTGAGGCGA ACAAAGTGGC TGTGAATATT CACAGACCCT CTAGAAAGTC AGTCACCAAG 
ATGCTGTTTG TCTTGGTCCT CGTGTTTGCC ATCTGCTGGA CCCCCTTCCA TGTGGACCGG 
CTCTTCTTCA GCTTTGTGGA AGAGTGGACA GAGTCCCTGG CTGCTGTGTT CAACCTCATC 
CATGTGGTAT CAGGTGTCTT CTTTTATCTG AGCTCCGCGG TCAACCCCAT TATCTATAAC 
CTCCTGTCTC GGCGCTTCCG GGCGGCCTTT CGAAATGTTG TCTCCCCTAC CTGCAAATGG 
TGCCATCCCC GGCATCGGCC ACAGGGACCT CCAGCCCAGA AGATCATCTT CTTGACAGAA 
TGTCACCTCG TGGAGCTGAC AGAGGATGCA GGCCCCCAGT TCCCTGGTCA GTCATCCATC 
CACAACACCA ACCTTACCAC GGCCCCCTGT GCAGGAGAGG TACCATAA