Selplg cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Selplg
Entrez Gene ID	363930
Full Name	selectin P ligand
Synonyms	Psgl1,Selpl
General protein information	Preferred Names selectin P ligand Names P-selectin glycoprotein ligand 1 P-selectin glycoprotein ligand 1 propeptide leukocyte cell surface adhesion molecule selectin, platelet (p-selectin) ligand
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013230.1	NP_001013248.1	P-selectin glycoprotein ligand 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SELPLG	XP_001164136.3
Mus musculus (house mouse)	Selplg	NP_033177.3
Rattus norvegicus (Norway rat)	Selplg	NP_001013248.1
Homo sapiens (human)	SELPLG	NP_001193538.1
Macaca mulatta (Rhesus monkey)	LOC706046	XP_002798810.1
Canis lupus familiaris (dog)	SELPLG	NP_001229648.1
Bos taurus (cattle)	SELPLG	NP_001032717.2

Gene Ontology
Bibliography

Related articles in PubMed

Lipid raft-associated β-adducin is required for PSGL-1-mediated neutrophil rolling on P-selectin.
Xu T, Liu W, Yang C, Ba X, Wang X, Jiang Y, Zeng X
Journal of leukocyte biology97(2)297-306(2015 Feb)

The sex-specific association of Met62Ile gene polymorphism in P-selectin glycoprotein ligand (PSGL-1) with carotid plaque presence: preliminary study.
Zivković M, Kolaković A, Radak D, Dinčić D, Radak S, Djurić T, Stanković A
Molecular biology reports39(6)6479-85(2012 Jun)

P-selectin glycoprotein ligand-1 is needed for sequential recruitment of T-helper 1 (Th1) and local generation of Th17 T cells in dextran sodium sulfate (DSS) colitis.
Brown JB, Cheresh P, Zhang Z, Ryu H, Managlia E, Barrett TA
Inflammatory bowel diseases18(2)323-32(2012 Feb)

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes.
Affentranger S, Martinelli S, Hahn J, Rossy J, Niggli V
BMC cell biology1228(2011 Jun)

Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver.
Wyllie S, Barshes NR, Gao FQ, Karpen SJ, Goss JA
World journal of gastroenterology14(44)6808-16(2008 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Selplg gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Selplg cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03886	NM_001013230.1 Latest version!	Rattus norvegicus selectin P ligand (Selplg), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Selplg ( NM_001013230.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001013248.1 Rattus norvegicus selectin P ligand (Selplg), mRNA.

Price & Availability↑

CloneID	ORa03886
Clone ID Related Accession (Same CDS sequence)	NM_001013230.1
Accession Version	NM_001013230.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Rattus norvegicus(Norway rat)
Product	P-selectin glycoprotein ligand 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF488785.1. On Mar 26, 2005 this sequence version replaced XM_344117.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00632252, SAMN00632259 [ECO:0000348] ##Evidence-Data-END##

ATGTTCCCAC ACTTCCTTCT GCTGCTGACC GTCTTGGGCC CTGGCAACAG CCTTCATCTG 
CAGGAGCCGT GGGGGCATGA AACCATGGAA GGCCTGGGCC CTGTGCATCT CCGGGAACGG 
AGACAGGTGG TTGGGGATGA TGATTTTGAA TACCCCGACT ACAGCGTGTA TGGCACAGAT 
CCCCCAGAAA CGTTGATAAG TGTCCCCAAC ATGGTGGCGG CTCACCTTGA GCTTCGGACA 
ATGGTGGCCG TGTTAGAGCA GAGAGTTTCC GCGGGGGCTG GAACTTCTGA GACTGTCACT 
GCGCAGGTTG CCACCACTGG CCCTGCTGAC CCGGATACAG AAAGGCCAGC AGTTGGGATG 
CTGAGCACTG AATCTGTCAC ACAGCGGAGA CTAAGCCCAG TGGAGATGAC TACCCGGCTA 
GCACCCACGG AGGCAGAGAC CTCACAGCCA GCACCCATAA AGGCAGAGAC CTCACAGCCA 
GCACCCATAA AGGCAGAGAC CTCACAGCCA GCACCCAGGG AGGCAGAGAC CTCACAGCCA 
GCACCCACGG AGGCAGAGAC CTCACAGCCA GCACCCACAA AGGCAGAGAC CTCACAGCCA 
GCACCCACAG AGGCAGAGAC CTCACAGCCA GCACCCACGG AGGTAGAGAC CTCACAGCCA 
GCACCCACAG AGGCAGAGAC CTCACAGCCA GCACCCACGG AGGCAGAGAC CTCACAGCCA 
GCGTCCACAG AGACAGAGAC CACCCAGCTT CCCAGGAGTC AGGTTGTAGA AAGTCTATTT 
ACAACATCTG CGGTCACAGA AGCCCCTTCT ACGGAACCCA CCGCCATGGA GACCCTGTCC 
ACAGAGGCTA ATGAGTCTGC CATCTTCCTT GGGCCTTCCA TTGGCCACTT ACCTGACACC 
GGGCTGAAGA AAGGGCTGAT TGTCACCCCT GGGAGTTCTC TGGCCCCAAC CCCGCCAGGG 
ACCTCGGACC TCATCCCGGT GAAGCAATGT TTGCTGGCCA TTCTCATCTT AGCCTCCCTG 
GCCACCATCT TCCTTGTGTG CACGGTGGTG CTGGCCGTCC GCCTCTCCCG TAAGACGCAC 
ATGTACCCAG TGCGGAACTA CTCCCCCACA GAGATGATCT GCATCTCATC CTTGCTTCCC 
GAGGGGGGTG ACGGGGCCCC TGTCACAGCC AACGGGGGCC TGCCCAAGGT CCAGGACCAG 
AAGACAGAAC GCAGTGGGGA CCCGGATGGG GATGACCTCA CCCTGCACAG CTTCCTCCCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013248.1
CDS	1..1263
Translation	MFPHFLLLLTVLGPGNSLHLQEPWGHETMEGLGPVHLRERRQVVGDDDFEYPDYSVYGTDPPETLISVPNMVAAHLELRTMVAVLEQRVSAGAGTSETVTAQVATTGPADPDTERPAVGMLSTESVTQRRLSPVEMTTRLAPTEAETSQPAPIKAETSQPAPIKAETSQPAPREAETSQPAPTEAETSQPAPTKAETSQPAPTEAETSQPAPTEVETSQPAPTEAETSQPAPTEAETSQPASTETETTQLPRSQVVESLFTTSAVTEAPSTEPTAMETLSTEANESAIFLGPSIGHLPDTGLKKGLIVTPGSSLAPTPPGTSDLIPVKQCLLAILILASLATIFLVCTVVLAVRLSRKTHMYPVRNYSPTEMICISSLLPEGGDGAPVTANGGLPKVQDQKTERSGDPDGDDLTLHSFLP

Target ORF information:

RefSeq Version	NM_001013230.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus selectin P ligand (Selplg), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013230.1

ORF Insert Sequence:

ATGTTCCCAC ACTTCCTTCT GCTGCTGACC GTCTTGGGCC CTGGCAACAG CCTTCATCTG 
CAGGAGCCGT GGGGGCATGA AACCATGGAA GGCCTGGGCC CTGTGCATCT CCGGGAACGG 
AGACAGGTGG TTGGGGATGA TGATTTTGAA TACCCCGACT ACAGCGTGTA TGGCACAGAT 
CCCCCAGAAA CGTTGATAAG TGTCCCCAAC ATGGTGGCGG CTCACCTTGA GCTTCGGACA 
ATGGTGGCCG TGTTAGAGCA GAGAGTTTCC GCGGGGGCTG GAACTTCTGA GACTGTCACT 
GCGCAGGTTG CCACCACTGG CCCTGCTGAC CCGGATACAG AAAGGCCAGC AGTTGGGATG 
CTGAGCACTG AATCTGTCAC ACAGCGGAGA CTAAGCCCAG TGGAGATGAC TACCCGGCTA 
GCACCCACGG AGGCAGAGAC CTCACAGCCA GCACCCATAA AGGCAGAGAC CTCACAGCCA 
GCACCCATAA AGGCAGAGAC CTCACAGCCA GCACCCAGGG AGGCAGAGAC CTCACAGCCA 
GCACCCACGG AGGCAGAGAC CTCACAGCCA GCACCCACAA AGGCAGAGAC CTCACAGCCA 
GCACCCACAG AGGCAGAGAC CTCACAGCCA GCACCCACGG AGGTAGAGAC CTCACAGCCA 
GCACCCACAG AGGCAGAGAC CTCACAGCCA GCACCCACGG AGGCAGAGAC CTCACAGCCA 
GCGTCCACAG AGACAGAGAC CACCCAGCTT CCCAGGAGTC AGGTTGTAGA AAGTCTATTT 
ACAACATCTG CGGTCACAGA AGCCCCTTCT ACGGAACCCA CCGCCATGGA GACCCTGTCC 
ACAGAGGCTA ATGAGTCTGC CATCTTCCTT GGGCCTTCCA TTGGCCACTT ACCTGACACC 
GGGCTGAAGA AAGGGCTGAT TGTCACCCCT GGGAGTTCTC TGGCCCCAAC CCCGCCAGGG 
ACCTCGGACC TCATCCCGGT GAAGCAATGT TTGCTGGCCA TTCTCATCTT AGCCTCCCTG 
GCCACCATCT TCCTTGTGTG CACGGTGGTG CTGGCCGTCC GCCTCTCCCG TAAGACGCAC 
ATGTACCCAG TGCGGAACTA CTCCCCCACA GAGATGATCT GCATCTCATC CTTGCTTCCC 
GAGGGGGGTG ACGGGGCCCC TGTCACAGCC AACGGGGGCC TGCCCAAGGT CCAGGACCAG 
AAGACAGAAC GCAGTGGGGA CCCGGATGGG GATGACCTCA CCCTGCACAG CTTCCTCCCT 
TAG