Fxr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fxr1
Entrez Gene ID	361927
Full Name	FMR1 autosomal homolog 1
Synonyms	Fxr1h
General protein information	Preferred Names FMR1 autosomal homolog 1 Names fragile X mental retardation syndrome-related protein 1 fragile X mental retardation gene 1, autosomal homolog fragile X mental retardation, autosomal homolog 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012179.2	NP_001012179.1	fragile X mental retardation syndrome-related protein 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	FXR1	NP_001012619.1
Macaca mulatta (Rhesus monkey)	FXR1	XP_002802948.1
Mus musculus (house mouse)	Fxr1	NP_001106659.1
Rattus norvegicus (Norway rat)	Fxr1	NP_001012179.1
Danio rerio (zebrafish)	fxr1	NP_958458.1
Xenopus tropicalis (tropical clawed frog)	fxr1	NP_001263426.1
Homo sapiens (human)	FXR1	NP_005078.2
Pan troglodytes (chimpanzee)	FXR1	XP_001169084.2
Bos taurus (cattle)	FXR1	NP_001033651.1
Canis lupus familiaris (dog)	FXR1	XP_005639804.1

Gene Ontology
Bibliography

Related articles in PubMed

Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Chu M, Novak SM, Cover C, Wang AA, Chinyere IR, Juneman EB, Zarnescu DC, Wong PK, Gregorio CC
Circulation137(6)605-618(2018 02)

Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in
Wang GX, Smith SJ, Mourrain P
eLife5(2016 10)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanhäusser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.
Cook D, Sanchez-Carbente Mdel R, Lachance C, Radzioch D, Tremblay S, Khandjian EW, DesGroseillers L, Murai KK
PloS one6(10)e26120(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fxr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fxr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02593	NM_001012179.2 Latest version!	Rattus norvegicus FMR1 autosomal homolog 1 (Fxr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fxr1 ( NM_001012179.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012179.1 Rattus norvegicus FMR1 autosomal homolog 1 (Fxr1), mRNA.

Price & Availability↑

CloneID	ORa02593
Clone ID Related Accession (Same CDS sequence)	NM_001012179.2
Accession Version	NM_001012179.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	fragile X mental retardation syndrome-related protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083807.1. On Oct 26, 2014 this sequence version replaced NM_001012179.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC083807.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCGGAGC TGACGGTGGA GGTTCGCGGC TCCAACGGGG CTTTCTACAA GGTATTTATC 
AAAGATGTCC ACGAAGACTC CCTCACAGTT GTTTTTGAAA ATAATTGGCA ACCAGAACGC 
CAGGTTCCGT TTAATGAAGT TCGATTACCA CCACCACCTG ATATAAAAAA AGAAATTAGT 
GAAGGAGATG AAGTAGAGGT ATATTCAAGA GCAAATGACC AAGAACCATG TGGATGGTGG 
CTGGCTAAAG TTCGGATGAT GAAAGGCGAG TTTTATGTCA TTGAATATGC TGCTTGTGAT 
GCCACTTACA ATGAAATAGT CACATTTGAA CGACTTCGGC CTGTCAATCA AAATAAAACT 
GTCAAAAAAA ATACCTTCTT TAAGTGCACA GTGGATGTTC CTGAGGATTT GAGAGAAGCG 
TGTGCTAATG AAAATGCCCA TAAAGATTTC AAGAAAGCAG TAGGAGCGTG CAGAATTTTC 
TATCATCCTG AAACTACCCA GCTAATGATA CTGTCGGCCA GTGAAGCAAC TGTGAAGAGA 
GTAAATATCT TAAGTGATAT GCATTTGCGA AGTATTCGGA CGAAGTTGAT GCTTATGTCC 
AGAAATGAAG AGGCCACTAA GCATTTAGAA TGCACAAAAC AGCTTGCAGC AGCTTTTCAT 
GAAGAATTTG TTGTGAGAGA AGATCTAATG GGCCTGGCAA TAGGAACGCA TGGTAGTAAC 
ATACAGCAAG CTAGGAAGGT CCCTGGAGTT ACTGCCATTG AGTTAGATGA AGATACTGGA 
ACGTTTAGAA TCTACGGAGA GAGTGCTGAG GCTGTAAAGA AAGCAAGAGG TTTCTTGGAA 
TTTGTGGAAG ATTTTATTCA AGTTCCCAGG AATCTTGTTG GAAAAGTTAT TGGAAAAAAT 
GGCAAAGTTA TTCAAGAAAT AGTGGATAAA TCTGGTGTGG TTCGAGTAAG AATTGAAGGA 
GACAATGAAA ATAAACTACC TAGAGAAGAT GGAATGGTTC CATTTGTATT TGTTGGCACT 
AAAGAAAGTA TTGGAAATGT GCAAGTTCTT CTAGAGTATC ACATTGCTTA CTTAAAGGAA 
GTGGAACAAC TAAGAATGGA ACGCCTGCAG ATCGATGAAC AGCTGCGACA GATTGGTATG 
GGTTTCAGAC CTTCTTCCAC CAGAGGGCCT GAAAAAGAGA AAGGATATGC CACTGATGAA 
AGTACCGTCT CTTCTGTACA AGGTTCTAGG TCTTATAGTG GAAGAGGCAG AGGTCGTCGG 
GGCCCTAATT ACACCTCCGG TTATGGTACA AATTCTGAGC TGTCTAACCC CTCCGAAACA 
GAATCTGAGC GTAAAGATGA GCTGAGTGAT TGGTCATTGG CAGGAGAAGA TGATCGAGAG 
ACTCGACATC AGCGAGACAG CAGGAGACGC CCAGGAGGAA GAGGCAGAAG TGTTTCTGGG 
GGACGAGGTC GTGGTGGACC ACGTGGTGGC AAATCCTCCA TCAGTTCTGT GCTCAAAGAT 
CCAGACAGCA ATCCATACAG CTTACTTGAT AATACAGAAT CAGATCAGAC TGCAGACACT 
GACGCCAGCG AATCTCACCA CAGTACTAAC CGTCGTAGGC GGTCTCGTAG ACGAAGGACT 
GATGAAGATG CTGTTCTGAT GGATGGAATG ACTGAATCTG ATACAGCCTC AGTTAATGAG 
AATGGGCTAG GCAAAAGATG TGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012179.1
CDS	8..1714
Translation	MAELTVEVRGSNGAFYKVFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESAEAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGMGFRPSSTRGPEKEKGYATDESTVSSVQGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRETRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLGKRCD

Target ORF information:

RefSeq Version	NM_001012179.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FMR1 autosomal homolog 1 (Fxr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012179.2

ORF Insert Sequence:

ATGGCGGAGC TGACGGTGGA GGTTCGCGGC TCCAACGGGG CTTTCTACAA GGTATTTATC 
AAAGATGTCC ACGAAGACTC CCTCACAGTT GTTTTTGAAA ATAATTGGCA ACCAGAACGC 
CAGGTTCCGT TTAATGAAGT TCGATTACCA CCACCACCTG ATATAAAAAA AGAAATTAGT 
GAAGGAGATG AAGTAGAGGT ATATTCAAGA GCAAATGACC AAGAACCATG TGGATGGTGG 
CTGGCTAAAG TTCGGATGAT GAAAGGCGAG TTTTATGTCA TTGAATATGC TGCTTGTGAT 
GCCACTTACA ATGAAATAGT CACATTTGAA CGACTTCGGC CTGTCAATCA AAATAAAACT 
GTCAAAAAAA ATACCTTCTT TAAGTGCACA GTGGATGTTC CTGAGGATTT GAGAGAAGCG 
TGTGCTAATG AAAATGCCCA TAAAGATTTC AAGAAAGCAG TAGGAGCGTG CAGAATTTTC 
TATCATCCTG AAACTACCCA GCTAATGATA CTGTCGGCCA GTGAAGCAAC TGTGAAGAGA 
GTAAATATCT TAAGTGATAT GCATTTGCGA AGTATTCGGA CGAAGTTGAT GCTTATGTCC 
AGAAATGAAG AGGCCACTAA GCATTTAGAA TGCACAAAAC AGCTTGCAGC AGCTTTTCAT 
GAAGAATTTG TTGTGAGAGA AGATCTAATG GGCCTGGCAA TAGGAACGCA TGGTAGTAAC 
ATACAGCAAG CTAGGAAGGT CCCTGGAGTT ACTGCCATTG AGTTAGATGA AGATACTGGA 
ACGTTTAGAA TCTACGGAGA GAGTGCTGAG GCTGTAAAGA AAGCAAGAGG TTTCTTGGAA 
TTTGTGGAAG ATTTTATTCA AGTTCCCAGG AATCTTGTTG GAAAAGTTAT TGGAAAAAAT 
GGCAAAGTTA TTCAAGAAAT AGTGGATAAA TCTGGTGTGG TTCGAGTAAG AATTGAAGGA 
GACAATGAAA ATAAACTACC TAGAGAAGAT GGAATGGTTC CATTTGTATT TGTTGGCACT 
AAAGAAAGTA TTGGAAATGT GCAAGTTCTT CTAGAGTATC ACATTGCTTA CTTAAAGGAA 
GTGGAACAAC TAAGAATGGA ACGCCTGCAG ATCGATGAAC AGCTGCGACA GATTGGTATG 
GGTTTCAGAC CTTCTTCCAC CAGAGGGCCT GAAAAAGAGA AAGGATATGC CACTGATGAA 
AGTACCGTCT CTTCTGTACA AGGTTCTAGG TCTTATAGTG GAAGAGGCAG AGGTCGTCGG 
GGCCCTAATT ACACCTCCGG TTATGGTACA AATTCTGAGC TGTCTAACCC CTCCGAAACA 
GAATCTGAGC GTAAAGATGA GCTGAGTGAT TGGTCATTGG CAGGAGAAGA TGATCGAGAG 
ACTCGACATC AGCGAGACAG CAGGAGACGC CCAGGAGGAA GAGGCAGAAG TGTTTCTGGG 
GGACGAGGTC GTGGTGGACC ACGTGGTGGC AAATCCTCCA TCAGTTCTGT GCTCAAAGAT 
CCAGACAGCA ATCCATACAG CTTACTTGAT AATACAGAAT CAGATCAGAC TGCAGACACT 
GACGCCAGCG AATCTCACCA CAGTACTAAC CGTCGTAGGC GGTCTCGTAG ACGAAGGACT 
GATGAAGATG CTGTTCTGAT GGATGGAATG ACTGAATCTG ATACAGCCTC AGTTAATGAG 
AATGGGCTAG GCAAAAGATG TGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Circulation137(6)605-618(2018 02)
Chu M,Novak SM,Cover C,Wang AA,Chinyere IR,Juneman EB,Zarnescu DC,Wong PK,Gregorio CC

Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in
eLife5(2016 10)
Wang GX,Smith SJ,Mourrain P

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.
PloS one6(10)e26120(2011)
Cook D,Sanchez-Carbente Mdel R,Lachance C,Radzioch D,Tremblay S,Khandjian EW,DesGroseillers L,Murai KK

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Fxr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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