Cog4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cog4
Entrez Gene ID	361407
Full Name	component of oligomeric golgi complex 4
General protein information	Preferred Names component of oligomeric golgi complex 4 Names conserved oligomeric Golgi complex subunit 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108449.1	NP_001101919.1	conserved oligomeric Golgi complex subunit 4

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008875	XP_552742.3
Oryza sativa (rice)	Os02g0456000	NP_001172943.1
Bos taurus (cattle)	COG4	NP_001029755.1
Mus musculus (house mouse)	Cog4	NP_598734.1
Gallus gallus (chicken)	COG4	NP_001012793.1
Danio rerio (zebrafish)	cog4	NP_001034912.1
Xenopus tropicalis (tropical clawed frog)	LOC100145689	NP_001120535.1
Canis lupus familiaris (dog)	COG4	XP_546836.1
Homo sapiens (human)	COG4	NP_056201.2
Pan troglodytes (chimpanzee)	COG4	XP_511080.3
Macaca mulatta (Rhesus monkey)	COG4	XP_002808350.1
Rattus norvegicus (Norway rat)	Cog4	NP_001101919.1
Drosophila melanogaster (fruit fly)	CG7456	NP_609413.1
Caenorhabditis elegans (roundworm)	cogc-4	NP_493966.1
Arabidopsis thaliana (thale cress)	AT4G01400	NP_001154198.1

Gene Ontology
Bibliography

Related articles in PubMed

Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.
Richardson BC, Smith RD, Ungar D, Nakamura A, Jeffrey PD, Lupashin VV, Hughson FM
Proceedings of the National Academy of Sciences of the United States of America106(32)13329-34(2009 Aug)

Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing.
Laufman O, Kedan A, Hong W, Lev S
The EMBO journal28(14)2006-17(2009 Jul)

The binary interacting network of the conserved oligomeric Golgi tethering complex.
Loh E, Hong W
The Journal of biological chemistry279(23)24640-8(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cog4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cog4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07344	NM_001108449.1 Latest version!	Rattus norvegicus component of oligomeric golgi complex 4 (Cog4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cog4 ( NM_001108449.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101919.1 Rattus norvegicus component of oligomeric golgi complex 4 (Cog4), mRNA.

Price & Availability↑

CloneID	ORa07344
Clone ID Related Accession (Same CDS sequence)	NM_001108449.1
Accession Version	NM_001108449.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2358bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527350400000
Organism	Rattus norvegicus(Norway rat)
Product	conserved oligomeric Golgi complex subunit 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473972.1. On or before Oct 4, 2007 this sequence version replaced XM_341688.3, XM_001075681.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGATG TGGAATCCCC TCCGAAGTTG TCAGGAGCGC CTCCACCACC TGAGGGGGTG 
GGAGGAGGTC ACTGCTCCGA AATCTCCACC GAGCTCATTC GCTCTCTGAC AGAGCTGCAG 
GAGCTGGAAG CTGTGTACGA ACGACTCTGC GGCGAAGAGA AAGTGGTGGA GAAAGAGCTG 
GATGCTCTTT TGGAACAGCA AAACACCATT GAAAGTAAGA TGGTCACTCT CCACAGGATG 
GGTCCCAACC TGCAGTTGAT TGAGGGAGAT GCAAAGCAAC TGGCTGGGAT GATCACCTTT 
ACCTGCAACC TAGCTGAAAA TGTGTCCAGC AAAGTCCGTC AGCTTGACCT GGCCAAGAAC 
CGCCTCTATC AGGCCATTCA GAGAGCAGAT GACATCTTGG ACCTGAAGTT CTGCATGGAT 
GGAGTTCAAA CTGCTTTGAG GAGTGAAGAT TATGAGCAGG CTGCAGCCCA CATTCATCGT 
TACTTGTGCC TGGACAAGTC TGTCATAGAG CTCAGTCGAC AAGGCAAAGA AGGAAGCATG 
ATTGATGCCA ACCTGAAATT ACTGCAGGAA GCTGAGCAAC GTCTTAAAGC CATAGTAGCA 
GAGAAGTTTG CTGCTGCTAC CAAAGAAGGG GATTTGCCCC AGGTGGAGCG ATTCTTCAAG 
ATCTTCCCAC TGCTGGGTTT ACATGAGGAT GGACTGAGCA AGTTCTCGGA ATACCTGTGC 
AAACAGGTGG CCAGTAAGGC TGAAGAGAAT CTGCTCTTGG TGCTGGGATC AGACATGAGT 
GATCGAAGAG CTGCAGTCAT CTTTGCGGAC ACTCTCACTC TCCTCTTTGA AGGGATTGCC 
CGAATTGTGG AAACCCACCA ACCCATAGTG GAGACTTACT ATGGGCCAGG GCGACTCTTT 
ACCCTGATCA AATATCTTCA AGTAGAATGT GACACGCAGG TAGAGAAGGT GGTAAACAAG 
TTCATCAAGC AAAGGGACTA CCACCAGCAG TTCCGGCTTG TCCAGAGTAA CTTGATGAGA 
AATTCTGCAA CAGAAAAAAT TGAACCAAGG GAGCTGGACC CCGTCTTGAC TGAGGTTACC 
CTGATGAATG CTCGAAGTGA ATTGTACTTA CGCTTCCTTA GGAAGAGGAT CAGTGCAGAT 
TTTGAGGTGG GGGACTCCAT GGCTTCAGAA GAAGTAAAGC AAGAGCACCA GAAGTGCCTG 
GACAAACTCC TCAATAACTG CCTATTGAGC TGTACCATGC AGGAGCTAGT TGGCTTCTAT 
ATTACCATGG AGGAGTACTT CATGAGAGAG ACTGTCAATA AGGCTGTGGC TCTGGATACC 
TATGAGAAGG GCCAGTTGAC ATCCAGCATG GTGGATGATG TCTTTTACAT TGTTAAAAAG 
TGCATTGGGC GTGCTCTGTC CAGCTCTAAC ATCGACTGTC TCTGTGCCAT GATCAACCTT 
GCAACCAGAG AGCTGGAAGC TGACTTCAGG GATGTTCTAT GTAATAAGCT AAGAATGGGC 
TTCCCAGCCA CCACCTTACA GGACATCCAG CGTGGGGTGA CGAGTGCCGT GAACATCATG 
CACAGCAGCC TCCAGCAAGG CAAGTTTGAC ACCAAAGGCA TCGAGAGCAC TGATGAAGCC 
AAGCTGTCCT TCCTGGTGAC TCTGAATAAT GTGGAAGTCT GCAGTGAGAA CATCTCAACT 
CTGAAGAAGA CTCTGGAGAG TGACTGCACC AAGCTCTTCA GTCAGGGCAT TGGAGGGGAA 
CAGGCCCAGG CCAAGTTTGA CAGCTGCCTT TCTGACTTAG CTGCTGTGTC CAACAAATTT 
CGAGACCTCT TGCAGGAAGG GTTGGCGGAG CTCAACAGTT CAGCAGTCAA GCCGCAGGTG 
CAACCTTGGA TCAACACTTT TCTCTCAGTC TCACACAGCA TCGAGGAGGA AGAATTCAAC 
GACTATGAGG CCAATGACCC CTGGGTACAG CAGTTCATCC TCAGCCTAGA ACAGCAGATG 
GCAGAGTTCA AGGCCAGCCT GTCCCCGGTC ATCTATGACA GCCTAACTGG CCTCATGACC 
AGCCTTGTTG CTGTTGAACT GGAAAAAGTG GTTCTGAAAT CCACCTTCAA CAGGCTAGGT 
GGTCTGCAGT TTGACAAGGA ACTCCGGTCA CTCATTGCTT ACCTTACCAC TGTGACCACC 
TGGACCATCC GAGACAAGTT CGCCCGGCTC TCCCAGATGG CTACAATCCT TAATCTAGAG 
CGGGTGACCG AGATACTAGA TTACTGGGGT GCTAACTCTG GCCCTTTGAC ATGGCGCCTC 
ACCCCTGCTG AAGTGCGACA GGTACTGGCT CTGCGCATAG ACTTCCGCAA TGAGGACATC 
AAGAGGCTGC GCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101919.1
CDS	20..2377
Translation	MADVESPPKLSGAPPPPEGVGGGHCSEISTELIRSLTELQELEAVYERLCGEEKVVEKELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHIHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAAATKEGDLPQVERFFKIFPLLGLHEDGLSKFSEYLCKQVASKAEENLLLVLGSDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLFTLIKYLQVECDTQVEKVVNKFIKQRDYHQQFRLVQSNLMRNSATEKIEPRELDPVLTEVTLMNARSELYLRFLRKRISADFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELVGFYITMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSNIDCLCAMINLATRELEADFRDVLCNKLRMGFPATTLQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKLSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLAELNSSAVKPQVQPWINTFLSVSHSIEEEEFNDYEANDPWVQQFILSLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGANSGPLTWRLTPAEVRQVLALRIDFRNEDIKRLRL

Target ORF information:

RefSeq Version	NM_001108449.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus component of oligomeric golgi complex 4 (Cog4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108449.1

ORF Insert Sequence:

ATGGCGGATG TGGAATCCCC TCCGAAGTTG TCAGGAGCGC CTCCACCACC TGAGGGGGTG 
GGAGGAGGTC ACTGCTCCGA AATCTCCACC GAGCTCATTC GCTCTCTGAC AGAGCTGCAG 
GAGCTGGAAG CTGTGTACGA ACGACTCTGC GGCGAAGAGA AAGTGGTGGA GAAAGAGCTG 
GATGCTCTTT TGGAACAGCA AAACACCATT GAAAGTAAGA TGGTCACTCT CCACAGGATG 
GGTCCCAACC TGCAGTTGAT TGAGGGAGAT GCAAAGCAAC TGGCTGGGAT GATCACCTTT 
ACCTGCAACC TAGCTGAAAA TGTGTCCAGC AAAGTCCGTC AGCTTGACCT GGCCAAGAAC 
CGCCTCTATC AGGCCATTCA GAGAGCAGAT GACATCTTGG ACCTGAAGTT CTGCATGGAT 
GGAGTTCAAA CTGCTTTGAG GAGTGAAGAT TATGAGCAGG CTGCAGCCCA CATTCATCGT 
TACTTGTGCC TGGACAAGTC TGTCATAGAG CTCAGTCGAC AAGGCAAAGA AGGAAGCATG 
ATTGATGCCA ACCTGAAATT ACTGCAGGAA GCTGAGCAAC GTCTTAAAGC CATAGTAGCA 
GAGAAGTTTG CTGCTGCTAC CAAAGAAGGG GATTTGCCCC AGGTGGAGCG ATTCTTCAAG 
ATCTTCCCAC TGCTGGGTTT ACATGAGGAT GGACTGAGCA AGTTCTCGGA ATACCTGTGC 
AAACAGGTGG CCAGTAAGGC TGAAGAGAAT CTGCTCTTGG TGCTGGGATC AGACATGAGT 
GATCGAAGAG CTGCAGTCAT CTTTGCGGAC ACTCTCACTC TCCTCTTTGA AGGGATTGCC 
CGAATTGTGG AAACCCACCA ACCCATAGTG GAGACTTACT ATGGGCCAGG GCGACTCTTT 
ACCCTGATCA AATATCTTCA AGTAGAATGT GACACGCAGG TAGAGAAGGT GGTAAACAAG 
TTCATCAAGC AAAGGGACTA CCACCAGCAG TTCCGGCTTG TCCAGAGTAA CTTGATGAGA 
AATTCTGCAA CAGAAAAAAT TGAACCAAGG GAGCTGGACC CCGTCTTGAC TGAGGTTACC 
CTGATGAATG CTCGAAGTGA ATTGTACTTA CGCTTCCTTA GGAAGAGGAT CAGTGCAGAT 
TTTGAGGTGG GGGACTCCAT GGCTTCAGAA GAAGTAAAGC AAGAGCACCA GAAGTGCCTG 
GACAAACTCC TCAATAACTG CCTATTGAGC TGTACCATGC AGGAGCTAGT TGGCTTCTAT 
ATTACCATGG AGGAGTACTT CATGAGAGAG ACTGTCAATA AGGCTGTGGC TCTGGATACC 
TATGAGAAGG GCCAGTTGAC ATCCAGCATG GTGGATGATG TCTTTTACAT TGTTAAAAAG 
TGCATTGGGC GTGCTCTGTC CAGCTCTAAC ATCGACTGTC TCTGTGCCAT GATCAACCTT 
GCAACCAGAG AGCTGGAAGC TGACTTCAGG GATGTTCTAT GTAATAAGCT AAGAATGGGC 
TTCCCAGCCA CCACCTTACA GGACATCCAG CGTGGGGTGA CGAGTGCCGT GAACATCATG 
CACAGCAGCC TCCAGCAAGG CAAGTTTGAC ACCAAAGGCA TCGAGAGCAC TGATGAAGCC 
AAGCTGTCCT TCCTGGTGAC TCTGAATAAT GTGGAAGTCT GCAGTGAGAA CATCTCAACT 
CTGAAGAAGA CTCTGGAGAG TGACTGCACC AAGCTCTTCA GTCAGGGCAT TGGAGGGGAA 
CAGGCCCAGG CCAAGTTTGA CAGCTGCCTT TCTGACTTAG CTGCTGTGTC CAACAAATTT 
CGAGACCTCT TGCAGGAAGG GTTGGCGGAG CTCAACAGTT CAGCAGTCAA GCCGCAGGTG 
CAACCTTGGA TCAACACTTT TCTCTCAGTC TCACACAGCA TCGAGGAGGA AGAATTCAAC 
GACTATGAGG CCAATGACCC CTGGGTACAG CAGTTCATCC TCAGCCTAGA ACAGCAGATG 
GCAGAGTTCA AGGCCAGCCT GTCCCCGGTC ATCTATGACA GCCTAACTGG CCTCATGACC 
AGCCTTGTTG CTGTTGAACT GGAAAAAGTG GTTCTGAAAT CCACCTTCAA CAGGCTAGGT 
GGTCTGCAGT TTGACAAGGA ACTCCGGTCA CTCATTGCTT ACCTTACCAC TGTGACCACC 
TGGACCATCC GAGACAAGTT CGCCCGGCTC TCCCAGATGG CTACAATCCT TAATCTAGAG 
CGGGTGACCG AGATACTAGA TTACTGGGGT GCTAACTCTG GCCCTTTGAC ATGGCGCCTC 
ACCCCTGCTG AAGTGCGACA GGTACTGGCT CTGCGCATAG ACTTCCGCAA TGAGGACATC 
AAGAGGCTGC GCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.
Proceedings of the National Academy of Sciences of the United States of America106(32)13329-34(2009 Aug)
Richardson BC,Smith RD,Ungar D,Nakamura A,Jeffrey PD,Lupashin VV,Hughson FM

Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing.
The EMBO journal28(14)2006-17(2009 Jul)
Laufman O,Kedan A,Hong W,Lev S

The binary interacting network of the conserved oligomeric Golgi tethering complex.
The Journal of biological chemistry279(23)24640-8(2004 Jun)
Loh E,Hong W

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Cog4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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