Fos cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fos
Entrez Gene ID	314322
Full Name	Fos proto-oncogene, AP-1 transcription factor subunit
Synonyms	c-fos
General protein information	Preferred Names Fos proto-oncogene, AP-1 transcription factor subunit Names proto-oncogene c-Fos FBJ murine osteosarcoma viral oncogene homolog FBJ osteosarcoma oncogene c-fos oncogene proto-oncogene cFOS v-fos FBJ murine osteosarcoma viral oncogene homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q31
Summary	an immediate early gene encoding a nuclear protein involved in signal transduction [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022197.2	NP_071533.1	proto-oncogene c-Fos

Pathways from BioSystems

Homologies

Bos taurus (cattle)	FOS	NP_877587.1
Rattus norvegicus (Norway rat)	Fos	NP_071533.1
Pan troglodytes (chimpanzee)	FOS	NP_001091891.1
Macaca mulatta (Rhesus monkey)	FOS	NP_001091869.1
Gallus gallus (chicken)	FOS	NP_990839.1
Xenopus tropicalis (tropical clawed frog)	fos	NP_001016200.1
Homo sapiens (human)	FOS	NP_005243.1
Mus musculus (house mouse)	Fos	NP_034364.1
Danio rerio (zebrafish)	fos	NP_991132.1
Canis lupus familiaris (dog)	FOS	XP_547914.1

Gene Ontology
Bibliography

Related articles in PubMed

Experience-dependent c-Fos expression in the primary chemosensory cortices of the rat.
Bamji-Stocke S, Biggs BT, Samuelsen CL
Brain research1701189-195(2018 12)

Stimulation of B-Raf increases c-Jun and c-Fos expression and upregulates AP-1-regulated gene transcription in insulinoma cells.
Langfermann DS, Rössler OG, Thiel G
Molecular and cellular endocrinology472126-139(2018 09)

Brain c-fos expression patterns induced by emotional stressors differing in nature and intensity.
Úbeda-Contreras J, Marín-Blasco I, Nadal R, Armario A
Brain structure & function223(5)2213-2227(2018 Jun)

Analysis of Fos expression in the rat olfactory neurogenic region following single exposure to maternal separation during different neonatal stages.
Fabianová K, Závodská M, Raček A, Angelidis A, Martončíková M, Račeková E
General physiology and biophysics37(3)275-283(2018 May)

c-Fos downregulation positively regulates EphA5 expression in a congenital hypothyroidism rat model.
Song H, Zheng Y, Cai F, Ma Y, Yang J, Wu Y
Journal of molecular histology49(2)147-155(2018 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fos gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fos cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12756	NM_022197.2 Latest version!	Rattus norvegicus Fos proto-oncogene, AP-1 transcription factor subunit (Fos), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fos ( NM_022197.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071533.1 Rattus norvegicus Fos proto-oncogene, AP-1 transcription factor subunit (Fos), mRNA.

Price & Availability↑

CloneID	ORa12756
Clone ID Related Accession (Same CDS sequence)	NM_022197.2
Accession Version	NM_022197.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	proto-oncogene c-Fos
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ089699.1. On May 25, 2007 this sequence version replaced NM_022197.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ149169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGATGTTCT CGGGTTTCAA CGCGGACTAC GAGGCGTCAT CCTCCCGCTG CAGTAGCGCC 
TCCCCGGCCG GGGACAGCCT TTCCTACTAC CATTCCCCAG CCGACTCCTT CTCCAGCATG 
GGCTCCCCTG TCAACACACA GGACTTTTGC GCAGATCTGT CCGTCTCTAG TGCCAACTTT 
ATCCCCACGG TGACAGCCAT CTCCACCAGC CCAGACCTGC AGTGGCTGGT GCAGCCCACT 
CTGGTCTCCT CCGTGGCCCC ATCGCAGACC AGAGCGCCCC ATCCTTACGG ACTCCCCACC 
CCGTCGACCG GGGCTTACGC CAGAGCGGGA GTGGTGAAGA CCATGTCAGG CGGCAGAGCG 
CAGAGCATCG GCAGAAGGGG CAAAGTAGAG CAGCTATCTC CTGAAGAGGA AGAGAAACGG 
AGAATCCGAA GGGAAAGGAA TAAGATGGCT GCAGCCAAGT GCCGGAATCG GAGGAGGGAG 
CTGACAGATA CGCTCCAAGC GGAGACAGAT CAACTTGAAG ACGAGAAGTC TGCGTTGCAG 
ACCGAGATTG CCAATCTACT GAAAGAGAAG GAAAAACTGG AGTTTATTTT GGCAGCCCAC 
CGACCTGCCT GCAAGATCCC CAATGACCTG GGCTTCCCAG AGGAGATGTC TGTGACCTCC 
CTGGACTTGA CTGGGGGTCT GCCTGAGGCT ACCACCCCAG AGTCTGAGGA GGCCTTCACC 
CTGCCTCTTC TCAATGACCC TGAGCCCAAG CCATCCTTGG AGCCGGTCAA GAACATTAGC 
AACATGGAGC TGAAGGCTGA ACCCTTTGAT GACTTCTTGT TTCCGGCATC ATCTAGGCCC 
AGTGGCTCGG AGACTGCCCG CTCTGTGCCA GATGTGGACC TGTCTGGTTC CTTCTATGCA 
GCAGACTGGG AGCCTCTGCA CAGCAGTTCC CTGGGGATGG GGCCCATGGT CACAGAGCTG 
GAGCCCCTGT GCACTCCCGT TGTCACCTGC ACTCCCAGCT GCACTACCTA TACGTCTTCC 
TTTGTCTTCA CCTACCCCGA GGCTGACTCC TTCCCTAGCT GCGCAGCTGC CCACCGAAAG 
GGCAGCAGCA GCAACGAGCC CTCCTCTGAC TCACTGAGCT CGCCCACACT GCTAGCCCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071533.1
CDS	153..1295
Translation	MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTPSTGAYARAGVVKTMSGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPNDLGFPEEMSVTSLDLTGGLPEATTPESEEAFTLPLLNDPEPKPSLEPVKNISNMELKAEPFDDFLFPASSRPSGSETARSVPDVDLSGSFYAADWEPLHSSSLGMGPMVTELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL

Target ORF information:

RefSeq Version	NM_022197.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Fos proto-oncogene, AP-1 transcription factor subunit (Fos), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022197.2

ORF Insert Sequence:

ATGATGTTCT CGGGTTTCAA CGCGGACTAC GAGGCGTCAT CCTCCCGCTG CAGTAGCGCC 
TCCCCGGCCG GGGACAGCCT TTCCTACTAC CATTCCCCAG CCGACTCCTT CTCCAGCATG 
GGCTCCCCTG TCAACACACA GGACTTTTGC GCAGATCTGT CCGTCTCTAG TGCCAACTTT 
ATCCCCACGG TGACAGCCAT CTCCACCAGC CCAGACCTGC AGTGGCTGGT GCAGCCCACT 
CTGGTCTCCT CCGTGGCCCC ATCGCAGACC AGAGCGCCCC ATCCTTACGG ACTCCCCACC 
CCGTCGACCG GGGCTTACGC CAGAGCGGGA GTGGTGAAGA CCATGTCAGG CGGCAGAGCG 
CAGAGCATCG GCAGAAGGGG CAAAGTAGAG CAGCTATCTC CTGAAGAGGA AGAGAAACGG 
AGAATCCGAA GGGAAAGGAA TAAGATGGCT GCAGCCAAGT GCCGGAATCG GAGGAGGGAG 
CTGACAGATA CGCTCCAAGC GGAGACAGAT CAACTTGAAG ACGAGAAGTC TGCGTTGCAG 
ACCGAGATTG CCAATCTACT GAAAGAGAAG GAAAAACTGG AGTTTATTTT GGCAGCCCAC 
CGACCTGCCT GCAAGATCCC CAATGACCTG GGCTTCCCAG AGGAGATGTC TGTGACCTCC 
CTGGACTTGA CTGGGGGTCT GCCTGAGGCT ACCACCCCAG AGTCTGAGGA GGCCTTCACC 
CTGCCTCTTC TCAATGACCC TGAGCCCAAG CCATCCTTGG AGCCGGTCAA GAACATTAGC 
AACATGGAGC TGAAGGCTGA ACCCTTTGAT GACTTCTTGT TTCCGGCATC ATCTAGGCCC 
AGTGGCTCGG AGACTGCCCG CTCTGTGCCA GATGTGGACC TGTCTGGTTC CTTCTATGCA 
GCAGACTGGG AGCCTCTGCA CAGCAGTTCC CTGGGGATGG GGCCCATGGT CACAGAGCTG 
GAGCCCCTGT GCACTCCCGT TGTCACCTGC ACTCCCAGCT GCACTACCTA TACGTCTTCC 
TTTGTCTTCA CCTACCCCGA GGCTGACTCC TTCCCTAGCT GCGCAGCTGC CCACCGAAAG 
GGCAGCAGCA GCAACGAGCC CTCCTCTGAC TCACTGAGCT CGCCCACACT GCTAGCCCTG 
TGA