Pragmin cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pragmin
Entrez Gene ID	306506
Full Name	PEAK1 related kinase activating pseudokinase 1
Synonyms	Pragmin,RGD1311793
General protein information	Preferred Names PEAK1 related kinase activating pseudokinase 1 Names tyrosine-protein kinase SgK223 pragma of Rnd2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q12.2

mRNA and Protein(s)

mRNA	Protein	Name
XM_017600132.1	XP_017455621.1	tyrosine-protein kinase SgK223 isoform X1
NM_001107315.1	NP_001100785.1	inactive tyrosine-protein kinase PRAG1
XM_017600131.1	XP_017455620.1	tyrosine-protein kinase SgK223 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC533821	XP_005226093.1
Canis lupus familiaris (dog)	LOC482885	XP_540000.3
Xenopus tropicalis (tropical clawed frog)	LOC100486686	XP_002936500.1
Mus musculus (house mouse)	D8Ertd82e	NP_766499.2
Rattus norvegicus (Norway rat)	Pragmin	NP_001100785.1
Homo sapiens (human)	SGK223	NP_001074295.1
Macaca mulatta (Rhesus monkey)	LOC706349	XP_001094718.1
Pan troglodytes (chimpanzee)	LOC472692	XP_001136236.1
Gallus gallus (chicken)	SGK223	XP_420588.4

Gene Ontology
Bibliography

Related articles in PubMed

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation.
Lecointre C, Simon V, Kerneur C, Allemand F, Fournet A, Montarras I, Pons JL, Gelin M, Brignatz C, Urbach S, Labesse G, Roche S
Structure (London, England : 1993)26(4)545-554.e4(2018 04)

Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association.
Patel O, Griffin MDW, Panjikar S, Dai W, Ma X, Chan H, Zheng C, Kropp A, Murphy JM, Daly RJ, Lucet IS
Nature communications8(1)1157(2017 10)

C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility.
Senda Y, Murata-Kamiya N, Hatakeyama M
Cancer science107(7)972-80(2016 Jul)

NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis.
Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Vasquez-Del Carpio R, Dahmane N, Robbins DJ, Capobianco AJ
Cancer research74(17)4741-51(2014 Sep)

Mammalian Pragmin regulates Src family kinases via the Glu-Pro-Ile-Tyr-Ala (EPIYA) motif that is exploited by bacterial effectors.
Safari F, Murata-Kamiya N, Saito Y, Hatakeyama M
Proceedings of the National Academy of Sciences of the United States of America108(36)14938-43(2011 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pragmin gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pragmin cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03273	NM_001107315.1 Latest version!	Rattus norvegicus PEAK1 related kinase activating pseudokinase 1 (Prag1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
ORa03273	XM_017600131.1 Latest version!	Rattus norvegicus pragma of Rnd2 (Pragmin), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
ORa03273	XM_017600132.1 Latest version!	Rattus norvegicus pragma of Rnd2 (Pragmin), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pragmin ( NM_001107315.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100785.1 Rattus norvegicus PEAK1 related kinase activating pseudokinase 1 (Prag1), mRNA.

Price & Availability↑

CloneID	ORa03273
Clone ID Related Accession (Same CDS sequence)	XM_017600132.1 , NM_001107315.1 , XM_017600131.1
Accession Version	NM_001107315.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577289600000
Organism	Rattus norvegicus(Norway rat)
Product	inactive tyrosine-protein kinase PRAG1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CH473970.2. On or before Oct 4, 2007 this sequence version replaced XM_001066723.1, XM_224908.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMN01906348 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC 
TTCTGCTTGA GGAGTGACCA TCAGCTCACA GCTGGCCACC CCAAAGCTAG AGCCAGCAGC 
CTACCCGCTG GAGCTCGCCT GCCTGCCAGG CCTGAGATTT GCCGCTTAGA GGATGAAGGT 
GTGAATGGCT TGGCCTACTC AAAGCCCACC ATTGCGGTAA AGCCCACCAT GATGACTTCT 
GAGACTGCCG ACTTGTGGAC TGAGGCCAGC CTGAGCGCTG AAGTTCCAAA GGTCAACTGG 
AGACGAACTC CAGGCAAGCT CCTGCTCCAG AAACAGGAAG ATGGGCCAAT AGTTTACCTC 
GGCAGCTTCC GAGGAATGCA GAAGGCTGCA GGCCCTCTCG CCTGCACAGA TAGCAACTCT 
CGTTGTCCCC CAGCCTACAC CATGGTCGGA CTGCATAACC TGGAGGCCCG AGTGGATAGG 
AACACCGCCC TCCAACCAGT GAATTTCCAG GAAGAGAAGG CTGGGAGGGA AGAGCTGCCC 
TCAGCTCAGG AGAGCTTTCG TCAGAAGCTA GCTGCCTTTA CAGGGATGAC GTCCAGCTGC 
CTCAAGGGCC CCAGACCCTG CACTTCTCCA CAGCCCTTGC GGGAGTCCCT GCCCTCAGAG 
GATGACAGTG ACCAAAGGTG CTCACCCTCA GGAGACAGCG AAGGTGGGGA GTACTGCTCC 
ATTTTGGACT GTCGTCCAGA ATCCAGAGAT GCTGTGCATA ACACCGAGGG CTCTGGCCGA 
CGGCGAGGGG ACTGCTCACC CATATGCTGG GAGCAGGGAA CATGTACAAG ACCAACAGAA 
GAGGAAAAGC AGGCTCTGAA CTTCCCCAGA GAGTGTTGTG GTCAGGGATC CACAGCAAAC 
CCACCCCACC TGGGCCCCAA GAAGCCGTCC CTTAACTCAG AGGCTGCCAG CTCTTCAGAT 
GGTCTGTCCT GTGGCAGCAG CCGCAGTGGT GCCAACAGCC CCTTTGCTCC ACACCTGGAG 
AATGACTACT GCTCTCTTGT GAAGGAGCCA ACCTCGGTGA AGCAGCAGGA CTCTGGCTGC 
CACTTAGTCA ACTCTGGCAA ATATGTGGGT CAAGCCGTGG ACCTCCAGCC CCCAGCCCTT 
CCTAGGGAGG CTGTGCAGCC TGAACCCATC TACGCCGAAA GTGCCAAGAG GAAGAAGGCA 
GCTCCGGTGC CTCAGAGGCC CGAGCCCAAG AAAGAGCAGG TCTCGTCTGG CCAAGTATGG 
ACAGGCGATA CCTGGTCTCA GAAGACACCC TCTGGCTGGA GCCAGGAAAG GGAAGGCCCA 
AACGCTGCTC CTCAGGTGGC AACCACTATT ACTGTTATTG CTGCTCACCC AGAAGAGGAC 
CATAGGACTA TTTATCTGAG CAGCCCAGAC TCTGCCGTGG GGGTGCAGTG GCCACGTGGG 
TCTTTGAACC AGGACTTACA TGGTAGTGGA GAAGAGCCTT TGGTCGTGCA GGGGCTAAGC 
TCAAGGGAGA GCCATCCACA TAATATGACA GAAAACTCGT CCAAAGAAAA GCCTGCCATA 
CCCCCCAAGC TGTCCAAAAG CAGCCCGGGA GGGTCCCCGG TGTCACCTGC AGCCCCCCCT 
CTGACTGACC ACAGTGATGG GAACACCAGT GGCAGCAGTG TCGGATCTCA GCCTTCGTCT 
AGAGTCCCTA CTAACCTAAC TTCTTCCTGC CAGACCAATG GTGTTGCCGC CGGTGACCCT 
GCCAAGTGTC CCCCACAAGC CAACTCTTCA GTCTTGGACC AGAGGCGGCC AAGATACCAG 
ACTGGTGCAT GGAGCCGCCA GTGCCGGATA GAGGAGGAGG AAGAGGTGGG GCAGGAGTTG 
TTGAGTCAAA GTTGGGGGAG AGAGTTGGAA AATGGTATTG CAGACCATTC AAACTCCTCT 
ACCTGGCACC GGCTCCATCC CATTGATGGC GCCTCTGGGC AGAACGGCAA AACTAACTCT 
GGGATGAGCA AATCAGCTTC CTTTGCGTTT GAGTTCCCAA AGGACAGAGG CAGATTGGAG 
TCATTCTCAC CCCCTCCCCC ACCTCCAAAG TCAAGGCACC TGTTAAAAAT GAACAAGAGC 
AGCTCTGACT TGGAGAAAGT GAGCCAGAGC TCTGCAGAAA GCCTCAGCCC GTCCTTCCGA 
GGGGCCCACG TCAGCTTCAC CACGGGCTCC ACAGATAGCC TAGCCTCGGA CTCCAGGACT 
TGCAGCGATG GAGGTCCATC GTGTGAAGCC ACCCACTCAC CCACCATCAG CGGGAAAAAG 
CTCTTTGCTC CCGTCCCTTT CCCGTCAGGC TCCACGGAGG ATGTGTCCCC CAGCGGTCCT 
GCACAGCCTC CTCCTCTGCC CCAGAAAAAG ATAGTGAGCC GTGCTGCCTC CTCCCCTGAT 
GGCTTCTTCT GGACCCAAGG TTCCCCTAAG CCACGCACAG CGAGTCCCAA GCTGAACCTA 
AGCCACTCGG AAACCAATGT TTGTGCCCAT GACGAGCCTC CTTTGAGCTA TTCCTTGAAC 
TCTGGAAACC ATCCCCACCA TGTCTTCTCC TCTTCTGAGC CTTTGGAGAA AGCTTTCAAA 
GGCAGTGTCC CCTGGGCCCC AGCTCTGGGT CCAGCAAACA GCAAAGGCGG TTGTGGGAGC 
CCCAATCTCC AGGGCAGAGC GGCCACCTCC ACCTCGTCAT CCCAGCTCAG CGTGTCCAGC 
CAGGCCTCCA CCGGCAGCAG CCAGCTTCAG CTGCACAGCC TGCTGAGCAG TATCAGCAGC 
AAGGAGGGCA CCTATGCCAA GCTCGGGGGC CTCTACACAC AGTCCCTGGC CCGCCTAGTG 
ACCAAGTGCG AAGACCTCTT CATGGGTGGT CTGAAAACGG AACTGCGCTT CGATGAGAAC 
AGCTGGTCGC TCTTCAAACT GATATGCAAC AAGCCTTGCT GTGACTCGGG AGATGCAATT 
TACTACGGTG CCACTTGCTC CAAGGACCCC GACAGCATCT ACGCAGTGAA AATCTGCAAA 
ACCCCAGAAC CCAAGTCAGC TTCGTACTGT AGCCCGTCCG TGCCAGTGCA CTTCAACATC 
CAGCAAGACT GCGGCCACTT TGTGGCCTCT GTGCCCTCCA GCATGCTTGC CTTCCCCGAC 
ACATCCAGCA AGGACCCTGC GCCTGCTGCG CCCTCACACA CCCCTGCCCA GGAGCAGGAC 
TGTGTGGTGG TCATCACCCG GGAGGTGCCG CACCAGACTG CCTCGGACTT TGTGCGGGAC 
TCTGTGGCCA GCCACCGCGC AGAGCCTGAG GTTTACGAGC GCCGGGTGTG CTTCTTGCTT 
CTGCAGCTCT GCAACGGGCT GGAGCATCTG AAGGAACATG GGATCATCCA CCGGGACCTA 
TGTCTGGAGA ACCTGTTGCT AGTGCATTGC AACCCTCAGA GCTCTCCCGG GCCCTCTGCT 
AATCCCAGCG TGCCCACCAC CACGTCCCGT TGTCCTTCTG CCGCACCCGC AGCCACCACA 
GCCTGCCAGG GAGGACCTGG TGAGAAGCAC CTGCCCAGGC TGATCATCAG CAACTTCCTG 
AAGGCCAAGC AGAAGCCGGG AGGCACCACC AACCTGCAAC AGAAGAAGAG CCAGGCCCGG 
CTGGCCCCTG AGATCGTATC TGCCTCTCAG TACCGTAAGT TTGATGAGTT CCAGACTGGC 
ATCCTCATCT ACGAGCTGCT CCACCAGCCC AACCCATTCG AGGTGCGAGC CCAGCTACGG 
GAGCGTGACT ACCGGCGGGA GGACCTACCC CCGCTGCCCA CACTGTCGCT CTACTCGCCC 
GGCCTGCAGC AGCTCGCCCA CCTGCTCCTT GAGGCCGATC CCATCAAGCG CATCCGCATA 
GGTGAGGCCA AGCGGGTGCT ACAGTGCTTG CTGTGGGGGC CACGGCGAGA GCTGGTAGAG 
CAGCCGTGCC CCTCGGAGGA GGTACTGTGC AACACTCTGC ACAACTGGAT CGACATGAAG 
CGAGCCCTGA TGATGATGAA GTTTGCCGAG AAGGCGGTAG AACGAAGGCG GGGTGTGGAG 
CTGGAGGATT GGCTCTGTTG CCAGTACTTG GCCTCAGCAG AGCCAGGGGC CCTCTTGCAG 
TCCCTGAAGC TCCTGCAACT TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100785.1
CDS	263..4369
Translation	MSACSDFVEHIWKPGSCKNCFCLRSDHQLTAGHPKARASSLPAGARLPARPEICRLEDEGVNGLAYSKPTIAVKPTMMTSETADLWTEASLSAEVPKVNWRRTPGKLLLQKQEDGPIVYLGSFRGMQKAAGPLACTDSNSRCPPAYTMVGLHNLEARVDRNTALQPVNFQEEKAGREELPSAQESFRQKLAAFTGMTSSCLKGPRPCTSPQPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCRPESRDAVHNTEGSGRRRGDCSPICWEQGTCTRPTEEEKQALNFPRECCGQGSTANPPHLGPKKPSLNSEAASSSDGLSCGSSRSGANSPFAPHLENDYCSLVKEPTSVKQQDSGCHLVNSGKYVGQAVDLQPPALPREAVQPEPIYAESAKRKKAAPVPQRPEPKKEQVSSGQVWTGDTWSQKTPSGWSQEREGPNAAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPRGSLNQDLHGSGEEPLVVQGLSSRESHPHNMTENSSKEKPAIPPKLSKSSPGGSPVSPAAPPLTDHSDGNTSGSSVGSQPSSRVPTNLTSSCQTNGVAAGDPAKCPPQANSSVLDQRRPRYQTGAWSRQCRIEEEEEVGQELLSQSWGRELENGIADHSNSSTWHRLHPIDGASGQNGKTNSGMSKSASFAFEFPKDRGRLESFSPPPPPPKSRHLLKMNKSSSDLEKVSQSSAESLSPSFRGAHVSFTTGSTDSLASDSRTCSDGGPSCEATHSPTISGKKLFAPVPFPSGSTEDVSPSGPAQPPPLPQKKIVSRAASSPDGFFWTQGSPKPRTASPKLNLSHSETNVCAHDEPPLSYSLNSGNHPHHVFSSSEPLEKAFKGSVPWAPALGPANSKGGCGSPNLQGRAATSTSSSQLSVSSQASTGSSQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGLKTELRFDENSWSLFKLICNKPCCDSGDAIYYGATCSKDPDSIYAVKICKTPEPKSASYCSPSVPVHFNIQQDCGHFVASVPSSMLAFPDTSSKDPAPAAPSHTPAQEQDCVVVITREVPHQTASDFVRDSVASHRAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCNPQSSPGPSANPSVPTTTSRCPSAAPAATTACQGGPGEKHLPRLIISNFLKAKQKPGGTTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVERRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL

Target ORF information:

RefSeq Version	NM_001107315.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus PEAK1 related kinase activating pseudokinase 1 (Prag1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107315.1

ORF Insert Sequence:

ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC 
TTCTGCTTGA GGAGTGACCA TCAGCTCACA GCTGGCCACC CCAAAGCTAG AGCCAGCAGC 
CTACCCGCTG GAGCTCGCCT GCCTGCCAGG CCTGAGATTT GCCGCTTAGA GGATGAAGGT 
GTGAATGGCT TGGCCTACTC AAAGCCCACC ATTGCGGTAA AGCCCACCAT GATGACTTCT 
GAGACTGCCG ACTTGTGGAC TGAGGCCAGC CTGAGCGCTG AAGTTCCAAA GGTCAACTGG 
AGACGAACTC CAGGCAAGCT CCTGCTCCAG AAACAGGAAG ATGGGCCAAT AGTTTACCTC 
GGCAGCTTCC GAGGAATGCA GAAGGCTGCA GGCCCTCTCG CCTGCACAGA TAGCAACTCT 
CGTTGTCCCC CAGCCTACAC CATGGTCGGA CTGCATAACC TGGAGGCCCG AGTGGATAGG 
AACACCGCCC TCCAACCAGT GAATTTCCAG GAAGAGAAGG CTGGGAGGGA AGAGCTGCCC 
TCAGCTCAGG AGAGCTTTCG TCAGAAGCTA GCTGCCTTTA CAGGGATGAC GTCCAGCTGC 
CTCAAGGGCC CCAGACCCTG CACTTCTCCA CAGCCCTTGC GGGAGTCCCT GCCCTCAGAG 
GATGACAGTG ACCAAAGGTG CTCACCCTCA GGAGACAGCG AAGGTGGGGA GTACTGCTCC 
ATTTTGGACT GTCGTCCAGA ATCCAGAGAT GCTGTGCATA ACACCGAGGG CTCTGGCCGA 
CGGCGAGGGG ACTGCTCACC CATATGCTGG GAGCAGGGAA CATGTACAAG ACCAACAGAA 
GAGGAAAAGC AGGCTCTGAA CTTCCCCAGA GAGTGTTGTG GTCAGGGATC CACAGCAAAC 
CCACCCCACC TGGGCCCCAA GAAGCCGTCC CTTAACTCAG AGGCTGCCAG CTCTTCAGAT 
GGTCTGTCCT GTGGCAGCAG CCGCAGTGGT GCCAACAGCC CCTTTGCTCC ACACCTGGAG 
AATGACTACT GCTCTCTTGT GAAGGAGCCA ACCTCGGTGA AGCAGCAGGA CTCTGGCTGC 
CACTTAGTCA ACTCTGGCAA ATATGTGGGT CAAGCCGTGG ACCTCCAGCC CCCAGCCCTT 
CCTAGGGAGG CTGTGCAGCC TGAACCCATC TACGCCGAAA GTGCCAAGAG GAAGAAGGCA 
GCTCCGGTGC CTCAGAGGCC CGAGCCCAAG AAAGAGCAGG TCTCGTCTGG CCAAGTATGG 
ACAGGCGATA CCTGGTCTCA GAAGACACCC TCTGGCTGGA GCCAGGAAAG GGAAGGCCCA 
AACGCTGCTC CTCAGGTGGC AACCACTATT ACTGTTATTG CTGCTCACCC AGAAGAGGAC 
CATAGGACTA TTTATCTGAG CAGCCCAGAC TCTGCCGTGG GGGTGCAGTG GCCACGTGGG 
TCTTTGAACC AGGACTTACA TGGTAGTGGA GAAGAGCCTT TGGTCGTGCA GGGGCTAAGC 
TCAAGGGAGA GCCATCCACA TAATATGACA GAAAACTCGT CCAAAGAAAA GCCTGCCATA 
CCCCCCAAGC TGTCCAAAAG CAGCCCGGGA GGGTCCCCGG TGTCACCTGC AGCCCCCCCT 
CTGACTGACC ACAGTGATGG GAACACCAGT GGCAGCAGTG TCGGATCTCA GCCTTCGTCT 
AGAGTCCCTA CTAACCTAAC TTCTTCCTGC CAGACCAATG GTGTTGCCGC CGGTGACCCT 
GCCAAGTGTC CCCCACAAGC CAACTCTTCA GTCTTGGACC AGAGGCGGCC AAGATACCAG 
ACTGGTGCAT GGAGCCGCCA GTGCCGGATA GAGGAGGAGG AAGAGGTGGG GCAGGAGTTG 
TTGAGTCAAA GTTGGGGGAG AGAGTTGGAA AATGGTATTG CAGACCATTC AAACTCCTCT 
ACCTGGCACC GGCTCCATCC CATTGATGGC GCCTCTGGGC AGAACGGCAA AACTAACTCT 
GGGATGAGCA AATCAGCTTC CTTTGCGTTT GAGTTCCCAA AGGACAGAGG CAGATTGGAG 
TCATTCTCAC CCCCTCCCCC ACCTCCAAAG TCAAGGCACC TGTTAAAAAT GAACAAGAGC 
AGCTCTGACT TGGAGAAAGT GAGCCAGAGC TCTGCAGAAA GCCTCAGCCC GTCCTTCCGA 
GGGGCCCACG TCAGCTTCAC CACGGGCTCC ACAGATAGCC TAGCCTCGGA CTCCAGGACT 
TGCAGCGATG GAGGTCCATC GTGTGAAGCC ACCCACTCAC CCACCATCAG CGGGAAAAAG 
CTCTTTGCTC CCGTCCCTTT CCCGTCAGGC TCCACGGAGG ATGTGTCCCC CAGCGGTCCT 
GCACAGCCTC CTCCTCTGCC CCAGAAAAAG ATAGTGAGCC GTGCTGCCTC CTCCCCTGAT 
GGCTTCTTCT GGACCCAAGG TTCCCCTAAG CCACGCACAG CGAGTCCCAA GCTGAACCTA 
AGCCACTCGG AAACCAATGT TTGTGCCCAT GACGAGCCTC CTTTGAGCTA TTCCTTGAAC 
TCTGGAAACC ATCCCCACCA TGTCTTCTCC TCTTCTGAGC CTTTGGAGAA AGCTTTCAAA 
GGCAGTGTCC CCTGGGCCCC AGCTCTGGGT CCAGCAAACA GCAAAGGCGG TTGTGGGAGC 
CCCAATCTCC AGGGCAGAGC GGCCACCTCC ACCTCGTCAT CCCAGCTCAG CGTGTCCAGC 
CAGGCCTCCA CCGGCAGCAG CCAGCTTCAG CTGCACAGCC TGCTGAGCAG TATCAGCAGC 
AAGGAGGGCA CCTATGCCAA GCTCGGGGGC CTCTACACAC AGTCCCTGGC CCGCCTAGTG 
ACCAAGTGCG AAGACCTCTT CATGGGTGGT CTGAAAACGG AACTGCGCTT CGATGAGAAC 
AGCTGGTCGC TCTTCAAACT GATATGCAAC AAGCCTTGCT GTGACTCGGG AGATGCAATT 
TACTACGGTG CCACTTGCTC CAAGGACCCC GACAGCATCT ACGCAGTGAA AATCTGCAAA 
ACCCCAGAAC CCAAGTCAGC TTCGTACTGT AGCCCGTCCG TGCCAGTGCA CTTCAACATC 
CAGCAAGACT GCGGCCACTT TGTGGCCTCT GTGCCCTCCA GCATGCTTGC CTTCCCCGAC 
ACATCCAGCA AGGACCCTGC GCCTGCTGCG CCCTCACACA CCCCTGCCCA GGAGCAGGAC 
TGTGTGGTGG TCATCACCCG GGAGGTGCCG CACCAGACTG CCTCGGACTT TGTGCGGGAC 
TCTGTGGCCA GCCACCGCGC AGAGCCTGAG GTTTACGAGC GCCGGGTGTG CTTCTTGCTT 
CTGCAGCTCT GCAACGGGCT GGAGCATCTG AAGGAACATG GGATCATCCA CCGGGACCTA 
TGTCTGGAGA ACCTGTTGCT AGTGCATTGC AACCCTCAGA GCTCTCCCGG GCCCTCTGCT 
AATCCCAGCG TGCCCACCAC CACGTCCCGT TGTCCTTCTG CCGCACCCGC AGCCACCACA 
GCCTGCCAGG GAGGACCTGG TGAGAAGCAC CTGCCCAGGC TGATCATCAG CAACTTCCTG 
AAGGCCAAGC AGAAGCCGGG AGGCACCACC AACCTGCAAC AGAAGAAGAG CCAGGCCCGG 
CTGGCCCCTG AGATCGTATC TGCCTCTCAG TACCGTAAGT TTGATGAGTT CCAGACTGGC 
ATCCTCATCT ACGAGCTGCT CCACCAGCCC AACCCATTCG AGGTGCGAGC CCAGCTACGG 
GAGCGTGACT ACCGGCGGGA GGACCTACCC CCGCTGCCCA CACTGTCGCT CTACTCGCCC 
GGCCTGCAGC AGCTCGCCCA CCTGCTCCTT GAGGCCGATC CCATCAAGCG CATCCGCATA 
GGTGAGGCCA AGCGGGTGCT ACAGTGCTTG CTGTGGGGGC CACGGCGAGA GCTGGTAGAG 
CAGCCGTGCC CCTCGGAGGA GGTACTGTGC AACACTCTGC ACAACTGGAT CGACATGAAG 
CGAGCCCTGA TGATGATGAA GTTTGCCGAG AAGGCGGTAG AACGAAGGCG GGGTGTGGAG 
CTGGAGGATT GGCTCTGTTG CCAGTACTTG GCCTCAGCAG AGCCAGGGGC CCTCTTGCAG 
TCCCTGAAGC TCCTGCAACT TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pragmin ( XM_017600132.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455621.1 Rattus norvegicus pragma of Rnd2 (Pragmin), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa03273
Clone ID Related Accession (Same CDS sequence)	XM_017600132.1 , NM_001107315.1 , XM_017600131.1
Accession Version	XM_017600132.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein kinase SgK223 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC 
TTCTGCTTGA GGAGTGACCA TCAGCTCACA GCTGGCCACC CCAAAGCTAG AGCCAGCAGC 
CTACCCGCTG GAGCTCGCCT GCCTGCCAGG CCTGAGATTT GCCGCTTAGA GGATGAAGGT 
GTGAATGGCT TGGCCTACTC AAAGCCCACC ATTGCGGTAA AGCCCACCAT GATGACTTCT 
GAGACTGCCG ACTTGTGGAC TGAGGCCAGC CTGAGCGCTG AAGTTCCAAA GGTCAACTGG 
AGACGAACTC CAGGCAAGCT CCTGCTCCAG AAACAGGAAG ATGGGCCAAT AGTTTACCTC 
GGCAGCTTCC GAGGAATGCA GAAGGCTGCA GGCCCTCTCG CCTGCACAGA TAGCAACTCT 
CGTTGTCCCC CAGCCTACAC CATGGTCGGA CTGCATAACC TGGAGGCCCG AGTGGATAGG 
AACACCGCCC TCCAACCAGT GAATTTCCAG GAAGAGAAGG CTGGGAGGGA AGAGCTGCCC 
TCAGCTCAGG AGAGCTTTCG TCAGAAGCTA GCTGCCTTTA CAGGGATGAC GTCCAGCTGC 
CTCAAGGGCC CCAGACCCTG CACTTCTCCA CAGCCCTTGC GGGAGTCCCT GCCCTCAGAG 
GATGACAGTG ACCAAAGGTG CTCACCCTCA GGAGACAGCG AAGGTGGGGA GTACTGCTCC 
ATTTTGGACT GTCGTCCAGA ATCCAGAGAT GCTGTGCATA ACACCGAGGG CTCTGGCCGA 
CGGCGAGGGG ACTGCTCACC CATATGCTGG GAGCAGGGAA CATGTACAAG ACCAACAGAA 
GAGGAAAAGC AGGCTCTGAA CTTCCCCAGA GAGTGTTGTG GTCAGGGATC CACAGCAAAC 
CCACCCCACC TGGGCCCCAA GAAGCCGTCC CTTAACTCAG AGGCTGCCAG CTCTTCAGAT 
GGTCTGTCCT GTGGCAGCAG CCGCAGTGGT GCCAACAGCC CCTTTGCTCC ACACCTGGAG 
AATGACTACT GCTCTCTTGT GAAGGAGCCA ACCTCGGTGA AGCAGCAGGA CTCTGGCTGC 
CACTTAGTCA ACTCTGGCAA ATATGTGGGT CAAGCCGTGG ACCTCCAGCC CCCAGCCCTT 
CCTAGGGAGG CTGTGCAGCC TGAACCCATC TACGCCGAAA GTGCCAAGAG GAAGAAGGCA 
GCTCCGGTGC CTCAGAGGCC CGAGCCCAAG AAAGAGCAGG TCTCGTCTGG CCAAGTATGG 
ACAGGCGATA CCTGGTCTCA GAAGACACCC TCTGGCTGGA GCCAGGAAAG GGAAGGCCCA 
AACGCTGCTC CTCAGGTGGC AACCACTATT ACTGTTATTG CTGCTCACCC AGAAGAGGAC 
CATAGGACTA TTTATCTGAG CAGCCCAGAC TCTGCCGTGG GGGTGCAGTG GCCACGTGGG 
TCTTTGAACC AGGACTTACA TGGTAGTGGA GAAGAGCCTT TGGTCGTGCA GGGGCTAAGC 
TCAAGGGAGA GCCATCCACA TAATATGACA GAAAACTCGT CCAAAGAAAA GCCTGCCATA 
CCCCCCAAGC TGTCCAAAAG CAGCCCGGGA GGGTCCCCGG TGTCACCTGC AGCCCCCCCT 
CTGACTGACC ACAGTGATGG GAACACCAGT GGCAGCAGTG TCGGATCTCA GCCTTCGTCT 
AGAGTCCCTA CTAACCTAAC TTCTTCCTGC CAGACCAATG GTGTTGCCGC CGGTGACCCT 
GCCAAGTGTC CCCCACAAGC CAACTCTTCA GTCTTGGACC AGAGGCGGCC AAGATACCAG 
ACTGGTGCAT GGAGCCGCCA GTGCCGGATA GAGGAGGAGG AAGAGGTGGG GCAGGAGTTG 
TTGAGTCAAA GTTGGGGGAG AGAGTTGGAA AATGGTATTG CAGACCATTC AAACTCCTCT 
ACCTGGCACC GGCTCCATCC CATTGATGGC GCCTCTGGGC AGAACGGCAA AACTAACTCT 
GGGATGAGCA AATCAGCTTC CTTTGCGTTT GAGTTCCCAA AGGACAGAGG CAGATTGGAG 
TCATTCTCAC CCCCTCCCCC ACCTCCAAAG TCAAGGCACC TGTTAAAAAT GAACAAGAGC 
AGCTCTGACT TGGAGAAAGT GAGCCAGAGC TCTGCAGAAA GCCTCAGCCC GTCCTTCCGA 
GGGGCCCACG TCAGCTTCAC CACGGGCTCC ACAGATAGCC TAGCCTCGGA CTCCAGGACT 
TGCAGCGATG GAGGTCCATC GTGTGAAGCC ACCCACTCAC CCACCATCAG CGGGAAAAAG 
CTCTTTGCTC CCGTCCCTTT CCCGTCAGGC TCCACGGAGG ATGTGTCCCC CAGCGGTCCT 
GCACAGCCTC CTCCTCTGCC CCAGAAAAAG ATAGTGAGCC GTGCTGCCTC CTCCCCTGAT 
GGCTTCTTCT GGACCCAAGG TTCCCCTAAG CCACGCACAG CGAGTCCCAA GCTGAACCTA 
AGCCACTCGG AAACCAATGT TTGTGCCCAT GACGAGCCTC CTTTGAGCTA TTCCTTGAAC 
TCTGGAAACC ATCCCCACCA TGTCTTCTCC TCTTCTGAGC CTTTGGAGAA AGCTTTCAAA 
GGCAGTGTCC CCTGGGCCCC AGCTCTGGGT CCAGCAAACA GCAAAGGCGG TTGTGGGAGC 
CCCAATCTCC AGGGCAGAGC GGCCACCTCC ACCTCGTCAT CCCAGCTCAG CGTGTCCAGC 
CAGGCCTCCA CCGGCAGCAG CCAGCTTCAG CTGCACAGCC TGCTGAGCAG TATCAGCAGC 
AAGGAGGGCA CCTATGCCAA GCTCGGGGGC CTCTACACAC AGTCCCTGGC CCGCCTAGTG 
ACCAAGTGCG AAGACCTCTT CATGGGTGGT CTGAAAACGG AACTGCGCTT CGATGAGAAC 
AGCTGGTCGC TCTTCAAACT GATATGCAAC AAGCCTTGCT GTGACTCGGG AGATGCAATT 
TACTACGGTG CCACTTGCTC CAAGGACCCC GACAGCATCT ACGCAGTGAA AATCTGCAAA 
ACCCCAGAAC CCAAGTCAGC TTCGTACTGT AGCCCGTCCG TGCCAGTGCA CTTCAACATC 
CAGCAAGACT GCGGCCACTT TGTGGCCTCT GTGCCCTCCA GCATGCTTGC CTTCCCCGAC 
ACATCCAGCA AGGACCCTGC GCCTGCTGCG CCCTCACACA CCCCTGCCCA GGAGCAGGAC 
TGTGTGGTGG TCATCACCCG GGAGGTGCCG CACCAGACTG CCTCGGACTT TGTGCGGGAC 
TCTGTGGCCA GCCACCGCGC AGAGCCTGAG GTTTACGAGC GCCGGGTGTG CTTCTTGCTT 
CTGCAGCTCT GCAACGGGCT GGAGCATCTG AAGGAACATG GGATCATCCA CCGGGACCTA 
TGTCTGGAGA ACCTGTTGCT AGTGCATTGC AACCCTCAGA GCTCTCCCGG GCCCTCTGCT 
AATCCCAGCG TGCCCACCAC CACGTCCCGT TGTCCTTCTG CCGCACCCGC AGCCACCACA 
GCCTGCCAGG GAGGACCTGG TGAGAAGCAC CTGCCCAGGC TGATCATCAG CAACTTCCTG 
AAGGCCAAGC AGAAGCCGGG AGGCACCACC AACCTGCAAC AGAAGAAGAG CCAGGCCCGG 
CTGGCCCCTG AGATCGTATC TGCCTCTCAG TACCGTAAGT TTGATGAGTT CCAGACTGGC 
ATCCTCATCT ACGAGCTGCT CCACCAGCCC AACCCATTCG AGGTGCGAGC CCAGCTACGG 
GAGCGTGACT ACCGGCGGGA GGACCTACCC CCGCTGCCCA CACTGTCGCT CTACTCGCCC 
GGCCTGCAGC AGCTCGCCCA CCTGCTCCTT GAGGCCGATC CCATCAAGCG CATCCGCATA 
GGTGAGGCCA AGCGGGTGCT ACAGTGCTTG CTGTGGGGGC CACGGCGAGA GCTGGTAGAG 
CAGCCGTGCC CCTCGGAGGA GGTACTGTGC AACACTCTGC ACAACTGGAT CGACATGAAG 
CGAGCCCTGA TGATGATGAA GTTTGCCGAG AAGGCGGTAG AACGAAGGCG GGGTGTGGAG 
CTGGAGGATT GGCTCTGTTG CCAGTACTTG GCCTCAGCAG AGCCAGGGGC CCTCTTGCAG 
TCCCTGAAGC TCCTGCAACT TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455621.1
CDS	244..4350
Translation	MSACSDFVEHIWKPGSCKNCFCLRSDHQLTAGHPKARASSLPAGARLPARPEICRLEDEGVNGLAYSKPTIAVKPTMMTSETADLWTEASLSAEVPKVNWRRTPGKLLLQKQEDGPIVYLGSFRGMQKAAGPLACTDSNSRCPPAYTMVGLHNLEARVDRNTALQPVNFQEEKAGREELPSAQESFRQKLAAFTGMTSSCLKGPRPCTSPQPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCRPESRDAVHNTEGSGRRRGDCSPICWEQGTCTRPTEEEKQALNFPRECCGQGSTANPPHLGPKKPSLNSEAASSSDGLSCGSSRSGANSPFAPHLENDYCSLVKEPTSVKQQDSGCHLVNSGKYVGQAVDLQPPALPREAVQPEPIYAESAKRKKAAPVPQRPEPKKEQVSSGQVWTGDTWSQKTPSGWSQEREGPNAAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPRGSLNQDLHGSGEEPLVVQGLSSRESHPHNMTENSSKEKPAIPPKLSKSSPGGSPVSPAAPPLTDHSDGNTSGSSVGSQPSSRVPTNLTSSCQTNGVAAGDPAKCPPQANSSVLDQRRPRYQTGAWSRQCRIEEEEEVGQELLSQSWGRELENGIADHSNSSTWHRLHPIDGASGQNGKTNSGMSKSASFAFEFPKDRGRLESFSPPPPPPKSRHLLKMNKSSSDLEKVSQSSAESLSPSFRGAHVSFTTGSTDSLASDSRTCSDGGPSCEATHSPTISGKKLFAPVPFPSGSTEDVSPSGPAQPPPLPQKKIVSRAASSPDGFFWTQGSPKPRTASPKLNLSHSETNVCAHDEPPLSYSLNSGNHPHHVFSSSEPLEKAFKGSVPWAPALGPANSKGGCGSPNLQGRAATSTSSSQLSVSSQASTGSSQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGLKTELRFDENSWSLFKLICNKPCCDSGDAIYYGATCSKDPDSIYAVKICKTPEPKSASYCSPSVPVHFNIQQDCGHFVASVPSSMLAFPDTSSKDPAPAAPSHTPAQEQDCVVVITREVPHQTASDFVRDSVASHRAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCNPQSSPGPSANPSVPTTTSRCPSAAPAATTACQGGPGEKHLPRLIISNFLKAKQKPGGTTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVERRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL

Target ORF information:

RefSeq Version	XM_017600132.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pragma of Rnd2 (Pragmin), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600132.1

ORF Insert Sequence:

ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC 
TTCTGCTTGA GGAGTGACCA TCAGCTCACA GCTGGCCACC CCAAAGCTAG AGCCAGCAGC 
CTACCCGCTG GAGCTCGCCT GCCTGCCAGG CCTGAGATTT GCCGCTTAGA GGATGAAGGT 
GTGAATGGCT TGGCCTACTC AAAGCCCACC ATTGCGGTAA AGCCCACCAT GATGACTTCT 
GAGACTGCCG ACTTGTGGAC TGAGGCCAGC CTGAGCGCTG AAGTTCCAAA GGTCAACTGG 
AGACGAACTC CAGGCAAGCT CCTGCTCCAG AAACAGGAAG ATGGGCCAAT AGTTTACCTC 
GGCAGCTTCC GAGGAATGCA GAAGGCTGCA GGCCCTCTCG CCTGCACAGA TAGCAACTCT 
CGTTGTCCCC CAGCCTACAC CATGGTCGGA CTGCATAACC TGGAGGCCCG AGTGGATAGG 
AACACCGCCC TCCAACCAGT GAATTTCCAG GAAGAGAAGG CTGGGAGGGA AGAGCTGCCC 
TCAGCTCAGG AGAGCTTTCG TCAGAAGCTA GCTGCCTTTA CAGGGATGAC GTCCAGCTGC 
CTCAAGGGCC CCAGACCCTG CACTTCTCCA CAGCCCTTGC GGGAGTCCCT GCCCTCAGAG 
GATGACAGTG ACCAAAGGTG CTCACCCTCA GGAGACAGCG AAGGTGGGGA GTACTGCTCC 
ATTTTGGACT GTCGTCCAGA ATCCAGAGAT GCTGTGCATA ACACCGAGGG CTCTGGCCGA 
CGGCGAGGGG ACTGCTCACC CATATGCTGG GAGCAGGGAA CATGTACAAG ACCAACAGAA 
GAGGAAAAGC AGGCTCTGAA CTTCCCCAGA GAGTGTTGTG GTCAGGGATC CACAGCAAAC 
CCACCCCACC TGGGCCCCAA GAAGCCGTCC CTTAACTCAG AGGCTGCCAG CTCTTCAGAT 
GGTCTGTCCT GTGGCAGCAG CCGCAGTGGT GCCAACAGCC CCTTTGCTCC ACACCTGGAG 
AATGACTACT GCTCTCTTGT GAAGGAGCCA ACCTCGGTGA AGCAGCAGGA CTCTGGCTGC 
CACTTAGTCA ACTCTGGCAA ATATGTGGGT CAAGCCGTGG ACCTCCAGCC CCCAGCCCTT 
CCTAGGGAGG CTGTGCAGCC TGAACCCATC TACGCCGAAA GTGCCAAGAG GAAGAAGGCA 
GCTCCGGTGC CTCAGAGGCC CGAGCCCAAG AAAGAGCAGG TCTCGTCTGG CCAAGTATGG 
ACAGGCGATA CCTGGTCTCA GAAGACACCC TCTGGCTGGA GCCAGGAAAG GGAAGGCCCA 
AACGCTGCTC CTCAGGTGGC AACCACTATT ACTGTTATTG CTGCTCACCC AGAAGAGGAC 
CATAGGACTA TTTATCTGAG CAGCCCAGAC TCTGCCGTGG GGGTGCAGTG GCCACGTGGG 
TCTTTGAACC AGGACTTACA TGGTAGTGGA GAAGAGCCTT TGGTCGTGCA GGGGCTAAGC 
TCAAGGGAGA GCCATCCACA TAATATGACA GAAAACTCGT CCAAAGAAAA GCCTGCCATA 
CCCCCCAAGC TGTCCAAAAG CAGCCCGGGA GGGTCCCCGG TGTCACCTGC AGCCCCCCCT 
CTGACTGACC ACAGTGATGG GAACACCAGT GGCAGCAGTG TCGGATCTCA GCCTTCGTCT 
AGAGTCCCTA CTAACCTAAC TTCTTCCTGC CAGACCAATG GTGTTGCCGC CGGTGACCCT 
GCCAAGTGTC CCCCACAAGC CAACTCTTCA GTCTTGGACC AGAGGCGGCC AAGATACCAG 
ACTGGTGCAT GGAGCCGCCA GTGCCGGATA GAGGAGGAGG AAGAGGTGGG GCAGGAGTTG 
TTGAGTCAAA GTTGGGGGAG AGAGTTGGAA AATGGTATTG CAGACCATTC AAACTCCTCT 
ACCTGGCACC GGCTCCATCC CATTGATGGC GCCTCTGGGC AGAACGGCAA AACTAACTCT 
GGGATGAGCA AATCAGCTTC CTTTGCGTTT GAGTTCCCAA AGGACAGAGG CAGATTGGAG 
TCATTCTCAC CCCCTCCCCC ACCTCCAAAG TCAAGGCACC TGTTAAAAAT GAACAAGAGC 
AGCTCTGACT TGGAGAAAGT GAGCCAGAGC TCTGCAGAAA GCCTCAGCCC GTCCTTCCGA 
GGGGCCCACG TCAGCTTCAC CACGGGCTCC ACAGATAGCC TAGCCTCGGA CTCCAGGACT 
TGCAGCGATG GAGGTCCATC GTGTGAAGCC ACCCACTCAC CCACCATCAG CGGGAAAAAG 
CTCTTTGCTC CCGTCCCTTT CCCGTCAGGC TCCACGGAGG ATGTGTCCCC CAGCGGTCCT 
GCACAGCCTC CTCCTCTGCC CCAGAAAAAG ATAGTGAGCC GTGCTGCCTC CTCCCCTGAT 
GGCTTCTTCT GGACCCAAGG TTCCCCTAAG CCACGCACAG CGAGTCCCAA GCTGAACCTA 
AGCCACTCGG AAACCAATGT TTGTGCCCAT GACGAGCCTC CTTTGAGCTA TTCCTTGAAC 
TCTGGAAACC ATCCCCACCA TGTCTTCTCC TCTTCTGAGC CTTTGGAGAA AGCTTTCAAA 
GGCAGTGTCC CCTGGGCCCC AGCTCTGGGT CCAGCAAACA GCAAAGGCGG TTGTGGGAGC 
CCCAATCTCC AGGGCAGAGC GGCCACCTCC ACCTCGTCAT CCCAGCTCAG CGTGTCCAGC 
CAGGCCTCCA CCGGCAGCAG CCAGCTTCAG CTGCACAGCC TGCTGAGCAG TATCAGCAGC 
AAGGAGGGCA CCTATGCCAA GCTCGGGGGC CTCTACACAC AGTCCCTGGC CCGCCTAGTG 
ACCAAGTGCG AAGACCTCTT CATGGGTGGT CTGAAAACGG AACTGCGCTT CGATGAGAAC 
AGCTGGTCGC TCTTCAAACT GATATGCAAC AAGCCTTGCT GTGACTCGGG AGATGCAATT 
TACTACGGTG CCACTTGCTC CAAGGACCCC GACAGCATCT ACGCAGTGAA AATCTGCAAA 
ACCCCAGAAC CCAAGTCAGC TTCGTACTGT AGCCCGTCCG TGCCAGTGCA CTTCAACATC 
CAGCAAGACT GCGGCCACTT TGTGGCCTCT GTGCCCTCCA GCATGCTTGC CTTCCCCGAC 
ACATCCAGCA AGGACCCTGC GCCTGCTGCG CCCTCACACA CCCCTGCCCA GGAGCAGGAC 
TGTGTGGTGG TCATCACCCG GGAGGTGCCG CACCAGACTG CCTCGGACTT TGTGCGGGAC 
TCTGTGGCCA GCCACCGCGC AGAGCCTGAG GTTTACGAGC GCCGGGTGTG CTTCTTGCTT 
CTGCAGCTCT GCAACGGGCT GGAGCATCTG AAGGAACATG GGATCATCCA CCGGGACCTA 
TGTCTGGAGA ACCTGTTGCT AGTGCATTGC AACCCTCAGA GCTCTCCCGG GCCCTCTGCT 
AATCCCAGCG TGCCCACCAC CACGTCCCGT TGTCCTTCTG CCGCACCCGC AGCCACCACA 
GCCTGCCAGG GAGGACCTGG TGAGAAGCAC CTGCCCAGGC TGATCATCAG CAACTTCCTG 
AAGGCCAAGC AGAAGCCGGG AGGCACCACC AACCTGCAAC AGAAGAAGAG CCAGGCCCGG 
CTGGCCCCTG AGATCGTATC TGCCTCTCAG TACCGTAAGT TTGATGAGTT CCAGACTGGC 
ATCCTCATCT ACGAGCTGCT CCACCAGCCC AACCCATTCG AGGTGCGAGC CCAGCTACGG 
GAGCGTGACT ACCGGCGGGA GGACCTACCC CCGCTGCCCA CACTGTCGCT CTACTCGCCC 
GGCCTGCAGC AGCTCGCCCA CCTGCTCCTT GAGGCCGATC CCATCAAGCG CATCCGCATA 
GGTGAGGCCA AGCGGGTGCT ACAGTGCTTG CTGTGGGGGC CACGGCGAGA GCTGGTAGAG 
CAGCCGTGCC CCTCGGAGGA GGTACTGTGC AACACTCTGC ACAACTGGAT CGACATGAAG 
CGAGCCCTGA TGATGATGAA GTTTGCCGAG AAGGCGGTAG AACGAAGGCG GGGTGTGGAG 
CTGGAGGATT GGCTCTGTTG CCAGTACTTG GCCTCAGCAG AGCCAGGGGC CCTCTTGCAG 
TCCCTGAAGC TCCTGCAACT TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pragmin ( XM_017600131.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455620.1 Rattus norvegicus pragma of Rnd2 (Pragmin), transcript variant X1, mRNA.

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CloneID	ORa03273
Clone ID Related Accession (Same CDS sequence)	XM_017600132.1 , NM_001107315.1 , XM_017600131.1
Accession Version	XM_017600131.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein kinase SgK223 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC 
TTCTGCTTGA GGAGTGACCA TCAGCTCACA GCTGGCCACC CCAAAGCTAG AGCCAGCAGC 
CTACCCGCTG GAGCTCGCCT GCCTGCCAGG CCTGAGATTT GCCGCTTAGA GGATGAAGGT 
GTGAATGGCT TGGCCTACTC AAAGCCCACC ATTGCGGTAA AGCCCACCAT GATGACTTCT 
GAGACTGCCG ACTTGTGGAC TGAGGCCAGC CTGAGCGCTG AAGTTCCAAA GGTCAACTGG 
AGACGAACTC CAGGCAAGCT CCTGCTCCAG AAACAGGAAG ATGGGCCAAT AGTTTACCTC 
GGCAGCTTCC GAGGAATGCA GAAGGCTGCA GGCCCTCTCG CCTGCACAGA TAGCAACTCT 
CGTTGTCCCC CAGCCTACAC CATGGTCGGA CTGCATAACC TGGAGGCCCG AGTGGATAGG 
AACACCGCCC TCCAACCAGT GAATTTCCAG GAAGAGAAGG CTGGGAGGGA AGAGCTGCCC 
TCAGCTCAGG AGAGCTTTCG TCAGAAGCTA GCTGCCTTTA CAGGGATGAC GTCCAGCTGC 
CTCAAGGGCC CCAGACCCTG CACTTCTCCA CAGCCCTTGC GGGAGTCCCT GCCCTCAGAG 
GATGACAGTG ACCAAAGGTG CTCACCCTCA GGAGACAGCG AAGGTGGGGA GTACTGCTCC 
ATTTTGGACT GTCGTCCAGA ATCCAGAGAT GCTGTGCATA ACACCGAGGG CTCTGGCCGA 
CGGCGAGGGG ACTGCTCACC CATATGCTGG GAGCAGGGAA CATGTACAAG ACCAACAGAA 
GAGGAAAAGC AGGCTCTGAA CTTCCCCAGA GAGTGTTGTG GTCAGGGATC CACAGCAAAC 
CCACCCCACC TGGGCCCCAA GAAGCCGTCC CTTAACTCAG AGGCTGCCAG CTCTTCAGAT 
GGTCTGTCCT GTGGCAGCAG CCGCAGTGGT GCCAACAGCC CCTTTGCTCC ACACCTGGAG 
AATGACTACT GCTCTCTTGT GAAGGAGCCA ACCTCGGTGA AGCAGCAGGA CTCTGGCTGC 
CACTTAGTCA ACTCTGGCAA ATATGTGGGT CAAGCCGTGG ACCTCCAGCC CCCAGCCCTT 
CCTAGGGAGG CTGTGCAGCC TGAACCCATC TACGCCGAAA GTGCCAAGAG GAAGAAGGCA 
GCTCCGGTGC CTCAGAGGCC CGAGCCCAAG AAAGAGCAGG TCTCGTCTGG CCAAGTATGG 
ACAGGCGATA CCTGGTCTCA GAAGACACCC TCTGGCTGGA GCCAGGAAAG GGAAGGCCCA 
AACGCTGCTC CTCAGGTGGC AACCACTATT ACTGTTATTG CTGCTCACCC AGAAGAGGAC 
CATAGGACTA TTTATCTGAG CAGCCCAGAC TCTGCCGTGG GGGTGCAGTG GCCACGTGGG 
TCTTTGAACC AGGACTTACA TGGTAGTGGA GAAGAGCCTT TGGTCGTGCA GGGGCTAAGC 
TCAAGGGAGA GCCATCCACA TAATATGACA GAAAACTCGT CCAAAGAAAA GCCTGCCATA 
CCCCCCAAGC TGTCCAAAAG CAGCCCGGGA GGGTCCCCGG TGTCACCTGC AGCCCCCCCT 
CTGACTGACC ACAGTGATGG GAACACCAGT GGCAGCAGTG TCGGATCTCA GCCTTCGTCT 
AGAGTCCCTA CTAACCTAAC TTCTTCCTGC CAGACCAATG GTGTTGCCGC CGGTGACCCT 
GCCAAGTGTC CCCCACAAGC CAACTCTTCA GTCTTGGACC AGAGGCGGCC AAGATACCAG 
ACTGGTGCAT GGAGCCGCCA GTGCCGGATA GAGGAGGAGG AAGAGGTGGG GCAGGAGTTG 
TTGAGTCAAA GTTGGGGGAG AGAGTTGGAA AATGGTATTG CAGACCATTC AAACTCCTCT 
ACCTGGCACC GGCTCCATCC CATTGATGGC GCCTCTGGGC AGAACGGCAA AACTAACTCT 
GGGATGAGCA AATCAGCTTC CTTTGCGTTT GAGTTCCCAA AGGACAGAGG CAGATTGGAG 
TCATTCTCAC CCCCTCCCCC ACCTCCAAAG TCAAGGCACC TGTTAAAAAT GAACAAGAGC 
AGCTCTGACT TGGAGAAAGT GAGCCAGAGC TCTGCAGAAA GCCTCAGCCC GTCCTTCCGA 
GGGGCCCACG TCAGCTTCAC CACGGGCTCC ACAGATAGCC TAGCCTCGGA CTCCAGGACT 
TGCAGCGATG GAGGTCCATC GTGTGAAGCC ACCCACTCAC CCACCATCAG CGGGAAAAAG 
CTCTTTGCTC CCGTCCCTTT CCCGTCAGGC TCCACGGAGG ATGTGTCCCC CAGCGGTCCT 
GCACAGCCTC CTCCTCTGCC CCAGAAAAAG ATAGTGAGCC GTGCTGCCTC CTCCCCTGAT 
GGCTTCTTCT GGACCCAAGG TTCCCCTAAG CCACGCACAG CGAGTCCCAA GCTGAACCTA 
AGCCACTCGG AAACCAATGT TTGTGCCCAT GACGAGCCTC CTTTGAGCTA TTCCTTGAAC 
TCTGGAAACC ATCCCCACCA TGTCTTCTCC TCTTCTGAGC CTTTGGAGAA AGCTTTCAAA 
GGCAGTGTCC CCTGGGCCCC AGCTCTGGGT CCAGCAAACA GCAAAGGCGG TTGTGGGAGC 
CCCAATCTCC AGGGCAGAGC GGCCACCTCC ACCTCGTCAT CCCAGCTCAG CGTGTCCAGC 
CAGGCCTCCA CCGGCAGCAG CCAGCTTCAG CTGCACAGCC TGCTGAGCAG TATCAGCAGC 
AAGGAGGGCA CCTATGCCAA GCTCGGGGGC CTCTACACAC AGTCCCTGGC CCGCCTAGTG 
ACCAAGTGCG AAGACCTCTT CATGGGTGGT CTGAAAACGG AACTGCGCTT CGATGAGAAC 
AGCTGGTCGC TCTTCAAACT GATATGCAAC AAGCCTTGCT GTGACTCGGG AGATGCAATT 
TACTACGGTG CCACTTGCTC CAAGGACCCC GACAGCATCT ACGCAGTGAA AATCTGCAAA 
ACCCCAGAAC CCAAGTCAGC TTCGTACTGT AGCCCGTCCG TGCCAGTGCA CTTCAACATC 
CAGCAAGACT GCGGCCACTT TGTGGCCTCT GTGCCCTCCA GCATGCTTGC CTTCCCCGAC 
ACATCCAGCA AGGACCCTGC GCCTGCTGCG CCCTCACACA CCCCTGCCCA GGAGCAGGAC 
TGTGTGGTGG TCATCACCCG GGAGGTGCCG CACCAGACTG CCTCGGACTT TGTGCGGGAC 
TCTGTGGCCA GCCACCGCGC AGAGCCTGAG GTTTACGAGC GCCGGGTGTG CTTCTTGCTT 
CTGCAGCTCT GCAACGGGCT GGAGCATCTG AAGGAACATG GGATCATCCA CCGGGACCTA 
TGTCTGGAGA ACCTGTTGCT AGTGCATTGC AACCCTCAGA GCTCTCCCGG GCCCTCTGCT 
AATCCCAGCG TGCCCACCAC CACGTCCCGT TGTCCTTCTG CCGCACCCGC AGCCACCACA 
GCCTGCCAGG GAGGACCTGG TGAGAAGCAC CTGCCCAGGC TGATCATCAG CAACTTCCTG 
AAGGCCAAGC AGAAGCCGGG AGGCACCACC AACCTGCAAC AGAAGAAGAG CCAGGCCCGG 
CTGGCCCCTG AGATCGTATC TGCCTCTCAG TACCGTAAGT TTGATGAGTT CCAGACTGGC 
ATCCTCATCT ACGAGCTGCT CCACCAGCCC AACCCATTCG AGGTGCGAGC CCAGCTACGG 
GAGCGTGACT ACCGGCGGGA GGACCTACCC CCGCTGCCCA CACTGTCGCT CTACTCGCCC 
GGCCTGCAGC AGCTCGCCCA CCTGCTCCTT GAGGCCGATC CCATCAAGCG CATCCGCATA 
GGTGAGGCCA AGCGGGTGCT ACAGTGCTTG CTGTGGGGGC CACGGCGAGA GCTGGTAGAG 
CAGCCGTGCC CCTCGGAGGA GGTACTGTGC AACACTCTGC ACAACTGGAT CGACATGAAG 
CGAGCCCTGA TGATGATGAA GTTTGCCGAG AAGGCGGTAG AACGAAGGCG GGGTGTGGAG 
CTGGAGGATT GGCTCTGTTG CCAGTACTTG GCCTCAGCAG AGCCAGGGGC CCTCTTGCAG 
TCCCTGAAGC TCCTGCAACT TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455620.1
CDS	299..4405
Translation	MSACSDFVEHIWKPGSCKNCFCLRSDHQLTAGHPKARASSLPAGARLPARPEICRLEDEGVNGLAYSKPTIAVKPTMMTSETADLWTEASLSAEVPKVNWRRTPGKLLLQKQEDGPIVYLGSFRGMQKAAGPLACTDSNSRCPPAYTMVGLHNLEARVDRNTALQPVNFQEEKAGREELPSAQESFRQKLAAFTGMTSSCLKGPRPCTSPQPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCRPESRDAVHNTEGSGRRRGDCSPICWEQGTCTRPTEEEKQALNFPRECCGQGSTANPPHLGPKKPSLNSEAASSSDGLSCGSSRSGANSPFAPHLENDYCSLVKEPTSVKQQDSGCHLVNSGKYVGQAVDLQPPALPREAVQPEPIYAESAKRKKAAPVPQRPEPKKEQVSSGQVWTGDTWSQKTPSGWSQEREGPNAAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPRGSLNQDLHGSGEEPLVVQGLSSRESHPHNMTENSSKEKPAIPPKLSKSSPGGSPVSPAAPPLTDHSDGNTSGSSVGSQPSSRVPTNLTSSCQTNGVAAGDPAKCPPQANSSVLDQRRPRYQTGAWSRQCRIEEEEEVGQELLSQSWGRELENGIADHSNSSTWHRLHPIDGASGQNGKTNSGMSKSASFAFEFPKDRGRLESFSPPPPPPKSRHLLKMNKSSSDLEKVSQSSAESLSPSFRGAHVSFTTGSTDSLASDSRTCSDGGPSCEATHSPTISGKKLFAPVPFPSGSTEDVSPSGPAQPPPLPQKKIVSRAASSPDGFFWTQGSPKPRTASPKLNLSHSETNVCAHDEPPLSYSLNSGNHPHHVFSSSEPLEKAFKGSVPWAPALGPANSKGGCGSPNLQGRAATSTSSSQLSVSSQASTGSSQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGLKTELRFDENSWSLFKLICNKPCCDSGDAIYYGATCSKDPDSIYAVKICKTPEPKSASYCSPSVPVHFNIQQDCGHFVASVPSSMLAFPDTSSKDPAPAAPSHTPAQEQDCVVVITREVPHQTASDFVRDSVASHRAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCNPQSSPGPSANPSVPTTTSRCPSAAPAATTACQGGPGEKHLPRLIISNFLKAKQKPGGTTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVERRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL

Target ORF information:

RefSeq Version	XM_017600131.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pragma of Rnd2 (Pragmin), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600131.1

ORF Insert Sequence:

ATGTCTGCGT GCAGTGACTT TGTGGAGCAC ATCTGGAAAC CCGGATCCTG CAAGAACTGC 
TTCTGCTTGA GGAGTGACCA TCAGCTCACA GCTGGCCACC CCAAAGCTAG AGCCAGCAGC 
CTACCCGCTG GAGCTCGCCT GCCTGCCAGG CCTGAGATTT GCCGCTTAGA GGATGAAGGT 
GTGAATGGCT TGGCCTACTC AAAGCCCACC ATTGCGGTAA AGCCCACCAT GATGACTTCT 
GAGACTGCCG ACTTGTGGAC TGAGGCCAGC CTGAGCGCTG AAGTTCCAAA GGTCAACTGG 
AGACGAACTC CAGGCAAGCT CCTGCTCCAG AAACAGGAAG ATGGGCCAAT AGTTTACCTC 
GGCAGCTTCC GAGGAATGCA GAAGGCTGCA GGCCCTCTCG CCTGCACAGA TAGCAACTCT 
CGTTGTCCCC CAGCCTACAC CATGGTCGGA CTGCATAACC TGGAGGCCCG AGTGGATAGG 
AACACCGCCC TCCAACCAGT GAATTTCCAG GAAGAGAAGG CTGGGAGGGA AGAGCTGCCC 
TCAGCTCAGG AGAGCTTTCG TCAGAAGCTA GCTGCCTTTA CAGGGATGAC GTCCAGCTGC 
CTCAAGGGCC CCAGACCCTG CACTTCTCCA CAGCCCTTGC GGGAGTCCCT GCCCTCAGAG 
GATGACAGTG ACCAAAGGTG CTCACCCTCA GGAGACAGCG AAGGTGGGGA GTACTGCTCC 
ATTTTGGACT GTCGTCCAGA ATCCAGAGAT GCTGTGCATA ACACCGAGGG CTCTGGCCGA 
CGGCGAGGGG ACTGCTCACC CATATGCTGG GAGCAGGGAA CATGTACAAG ACCAACAGAA 
GAGGAAAAGC AGGCTCTGAA CTTCCCCAGA GAGTGTTGTG GTCAGGGATC CACAGCAAAC 
CCACCCCACC TGGGCCCCAA GAAGCCGTCC CTTAACTCAG AGGCTGCCAG CTCTTCAGAT 
GGTCTGTCCT GTGGCAGCAG CCGCAGTGGT GCCAACAGCC CCTTTGCTCC ACACCTGGAG 
AATGACTACT GCTCTCTTGT GAAGGAGCCA ACCTCGGTGA AGCAGCAGGA CTCTGGCTGC 
CACTTAGTCA ACTCTGGCAA ATATGTGGGT CAAGCCGTGG ACCTCCAGCC CCCAGCCCTT 
CCTAGGGAGG CTGTGCAGCC TGAACCCATC TACGCCGAAA GTGCCAAGAG GAAGAAGGCA 
GCTCCGGTGC CTCAGAGGCC CGAGCCCAAG AAAGAGCAGG TCTCGTCTGG CCAAGTATGG 
ACAGGCGATA CCTGGTCTCA GAAGACACCC TCTGGCTGGA GCCAGGAAAG GGAAGGCCCA 
AACGCTGCTC CTCAGGTGGC AACCACTATT ACTGTTATTG CTGCTCACCC AGAAGAGGAC 
CATAGGACTA TTTATCTGAG CAGCCCAGAC TCTGCCGTGG GGGTGCAGTG GCCACGTGGG 
TCTTTGAACC AGGACTTACA TGGTAGTGGA GAAGAGCCTT TGGTCGTGCA GGGGCTAAGC 
TCAAGGGAGA GCCATCCACA TAATATGACA GAAAACTCGT CCAAAGAAAA GCCTGCCATA 
CCCCCCAAGC TGTCCAAAAG CAGCCCGGGA GGGTCCCCGG TGTCACCTGC AGCCCCCCCT 
CTGACTGACC ACAGTGATGG GAACACCAGT GGCAGCAGTG TCGGATCTCA GCCTTCGTCT 
AGAGTCCCTA CTAACCTAAC TTCTTCCTGC CAGACCAATG GTGTTGCCGC CGGTGACCCT 
GCCAAGTGTC CCCCACAAGC CAACTCTTCA GTCTTGGACC AGAGGCGGCC AAGATACCAG 
ACTGGTGCAT GGAGCCGCCA GTGCCGGATA GAGGAGGAGG AAGAGGTGGG GCAGGAGTTG 
TTGAGTCAAA GTTGGGGGAG AGAGTTGGAA AATGGTATTG CAGACCATTC AAACTCCTCT 
ACCTGGCACC GGCTCCATCC CATTGATGGC GCCTCTGGGC AGAACGGCAA AACTAACTCT 
GGGATGAGCA AATCAGCTTC CTTTGCGTTT GAGTTCCCAA AGGACAGAGG CAGATTGGAG 
TCATTCTCAC CCCCTCCCCC ACCTCCAAAG TCAAGGCACC TGTTAAAAAT GAACAAGAGC 
AGCTCTGACT TGGAGAAAGT GAGCCAGAGC TCTGCAGAAA GCCTCAGCCC GTCCTTCCGA 
GGGGCCCACG TCAGCTTCAC CACGGGCTCC ACAGATAGCC TAGCCTCGGA CTCCAGGACT 
TGCAGCGATG GAGGTCCATC GTGTGAAGCC ACCCACTCAC CCACCATCAG CGGGAAAAAG 
CTCTTTGCTC CCGTCCCTTT CCCGTCAGGC TCCACGGAGG ATGTGTCCCC CAGCGGTCCT 
GCACAGCCTC CTCCTCTGCC CCAGAAAAAG ATAGTGAGCC GTGCTGCCTC CTCCCCTGAT 
GGCTTCTTCT GGACCCAAGG TTCCCCTAAG CCACGCACAG CGAGTCCCAA GCTGAACCTA 
AGCCACTCGG AAACCAATGT TTGTGCCCAT GACGAGCCTC CTTTGAGCTA TTCCTTGAAC 
TCTGGAAACC ATCCCCACCA TGTCTTCTCC TCTTCTGAGC CTTTGGAGAA AGCTTTCAAA 
GGCAGTGTCC CCTGGGCCCC AGCTCTGGGT CCAGCAAACA GCAAAGGCGG TTGTGGGAGC 
CCCAATCTCC AGGGCAGAGC GGCCACCTCC ACCTCGTCAT CCCAGCTCAG CGTGTCCAGC 
CAGGCCTCCA CCGGCAGCAG CCAGCTTCAG CTGCACAGCC TGCTGAGCAG TATCAGCAGC 
AAGGAGGGCA CCTATGCCAA GCTCGGGGGC CTCTACACAC AGTCCCTGGC CCGCCTAGTG 
ACCAAGTGCG AAGACCTCTT CATGGGTGGT CTGAAAACGG AACTGCGCTT CGATGAGAAC 
AGCTGGTCGC TCTTCAAACT GATATGCAAC AAGCCTTGCT GTGACTCGGG AGATGCAATT 
TACTACGGTG CCACTTGCTC CAAGGACCCC GACAGCATCT ACGCAGTGAA AATCTGCAAA 
ACCCCAGAAC CCAAGTCAGC TTCGTACTGT AGCCCGTCCG TGCCAGTGCA CTTCAACATC 
CAGCAAGACT GCGGCCACTT TGTGGCCTCT GTGCCCTCCA GCATGCTTGC CTTCCCCGAC 
ACATCCAGCA AGGACCCTGC GCCTGCTGCG CCCTCACACA CCCCTGCCCA GGAGCAGGAC 
TGTGTGGTGG TCATCACCCG GGAGGTGCCG CACCAGACTG CCTCGGACTT TGTGCGGGAC 
TCTGTGGCCA GCCACCGCGC AGAGCCTGAG GTTTACGAGC GCCGGGTGTG CTTCTTGCTT 
CTGCAGCTCT GCAACGGGCT GGAGCATCTG AAGGAACATG GGATCATCCA CCGGGACCTA 
TGTCTGGAGA ACCTGTTGCT AGTGCATTGC AACCCTCAGA GCTCTCCCGG GCCCTCTGCT 
AATCCCAGCG TGCCCACCAC CACGTCCCGT TGTCCTTCTG CCGCACCCGC AGCCACCACA 
GCCTGCCAGG GAGGACCTGG TGAGAAGCAC CTGCCCAGGC TGATCATCAG CAACTTCCTG 
AAGGCCAAGC AGAAGCCGGG AGGCACCACC AACCTGCAAC AGAAGAAGAG CCAGGCCCGG 
CTGGCCCCTG AGATCGTATC TGCCTCTCAG TACCGTAAGT TTGATGAGTT CCAGACTGGC 
ATCCTCATCT ACGAGCTGCT CCACCAGCCC AACCCATTCG AGGTGCGAGC CCAGCTACGG 
GAGCGTGACT ACCGGCGGGA GGACCTACCC CCGCTGCCCA CACTGTCGCT CTACTCGCCC 
GGCCTGCAGC AGCTCGCCCA CCTGCTCCTT GAGGCCGATC CCATCAAGCG CATCCGCATA 
GGTGAGGCCA AGCGGGTGCT ACAGTGCTTG CTGTGGGGGC CACGGCGAGA GCTGGTAGAG 
CAGCCGTGCC CCTCGGAGGA GGTACTGTGC AACACTCTGC ACAACTGGAT CGACATGAAG 
CGAGCCCTGA TGATGATGAA GTTTGCCGAG AAGGCGGTAG AACGAAGGCG GGGTGTGGAG 
CTGGAGGATT GGCTCTGTTG CCAGTACTTG GCCTCAGCAG AGCCAGGGGC CCTCTTGCAG 
TCCCTGAAGC TCCTGCAACT TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation.
Structure (London, England : 1993)26(4)545-554.e4(2018 04)
Lecointre C,Simon V,Kerneur C,Allemand F,Fournet A,Montarras I,Pons JL,Gelin M,Brignatz C,Urbach S,Labesse G,Roche S

Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association.
Nature communications8(1)1157(2017 10)
Patel O,Griffin MDW,Panjikar S,Dai W,Ma X,Chan H,Zheng C,Kropp A,Murphy JM,Daly RJ,Lucet IS

C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility.
Cancer science107(7)972-80(2016 Jul)
Senda Y,Murata-Kamiya N,Hatakeyama M

NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis.
Cancer research74(17)4741-51(2014 Sep)
Weaver KL,Alves-Guerra MC,Jin K,Wang Z,Han X,Ranganathan P,Zhu X,DaSilva T,Liu W,Ratti F,Demarest RM,Tzimas C,Rice M,Vasquez-Del Carpio R,Dahmane N,Robbins DJ,Capobianco AJ

Mammalian Pragmin regulates Src family kinases via the Glu-Pro-Ile-Tyr-Ala (EPIYA) motif that is exploited by bacterial effectors.
Proceedings of the National Academy of Sciences of the United States of America108(36)14938-43(2011 Sep)
Safari F,Murata-Kamiya N,Saito Y,Hatakeyama M

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Pragmin cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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