Fcgr1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fcgr1a
Entrez Gene ID	295279
Full Name	Fc fragment of IgG receptor Ia
Synonyms	FcgammaRI,Fcgr1,Fcgr1b
General protein information	Preferred Names Fc fragment of IgG receptor Ia Names high affinity immunoglobulin gamma Fc receptor I Fc fragment of IgG high affinity Ib receptor Fc fragment of IgG, high affinity Ia, receptor (CD64) Fc fragment of IgG, high affinity Ib, receptor for (CD64) Fc receptor, IgG, high affinity I high affinity IgG Fc receptor, subunit beta high-affinity immunoglobulin gamma Fc receptor I
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	human homolog is a high-affinity receptor for immunoglobulin G [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100836.1	NP_001094306.1	high affinity immunoglobulin gamma Fc receptor I precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FCGR1A	XP_001165641.1
Homo sapiens (human)	FCGR1A	NP_000557.1
Canis lupus familiaris (dog)	FCGR1A	NP_001002976.1
Bos taurus (cattle)	FCGR1A	NP_776963.1
Rattus norvegicus (Norway rat)	Fcgr1a	NP_001094306.1
Mus musculus (house mouse)	Fcgr1	NP_034316.1

Gene Ontology
Bibliography

Related articles in PubMed

Ovariectomy and subsequent treatment with estrogen receptor agonists tune the innate immune system of the hippocampus in middle-aged female rats.
Sárvári M, Kalló I, Hrabovszky E, Solymosi N, Liposits Z
PloS one9(2)e88540(2014)

Neuron-derived IgG protects dopaminergic neurons from insult by 6-OHDA and activates microglia through the FcγR I and TLR4 pathways.
Zhang J, Niu N, Wang M, McNutt MA, Zhang D, Zhang B, Lu S, Liu Y, Liu Z
The international journal of biochemistry & cell biology45(8)1911-20(2013 Aug)

Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage.
Fet NG, Fiebeler A, Klinge U, Park JK, Barth S, Thepen T, Tolba RH
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association27(8)3149-55(2012 Aug)

FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.
Serezani CH, Aronoff DM, Sitrin RG, Peters-Golden M
Blood114(15)3316-24(2009 Oct)

Delay of LPS-induced acute lung injury resolution by soluble immune complexes is neutrophil dependent.
Wu CL, Lin LY, Yeh HM, Chan MC, Yang CH, Hsueh CM
Shock (Augusta, Ga.)32(3)276-85(2009 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fcgr1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fcgr1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10956	NM_001100836.1 Latest version!	Rattus norvegicus Fc fragment of IgG receptor Ia (Fcgr1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fcgr1a ( NM_001100836.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094306.1 Rattus norvegicus Fc fragment of IgG receptor Ia (Fcgr1a), mRNA.

Price & Availability↑

CloneID	ORa10956
Clone ID Related Accession (Same CDS sequence)	NM_001100836.1
Accession Version	NM_001100836.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Rattus norvegicus(Norway rat)
Product	high affinity immunoglobulin gamma Fc receptor I precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CO555980.1, CF113031.1 and AA859169.1. On or before Oct 25, 2007 this sequence version replaced XM_001062370.1, XM_215643.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC158809.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTGGCTTC TAACGACTCT GCTACTTTGG GTTCCAGTTG GTGGGCAAGT AGTTAATGCC 
ACAAAGGCTG TGGTCACCTT GCAGCCCCCA TGGCTCAGCA TTTTCCAGGA GGAAAATGTC 
ACTTTGTTGT GTGAGGGACC TCACCTGGGA GACAGTTCCA CAAAGTGGTT TATCAACAGC 
ACAGCCATTC AGATCTCCAC ACCTACCTAT AGCATCCTCA AGGCCAGTTT CAAGGACAGT 
GGTGAATACA AGTGTCAGAC AGGTCTCTCA ATGCCAAGTG ACCCTGTGCA GTTAGAAATC 
TACAGAGATT GGCTGCTACT CCAGACCTCC CACAGAGTCC TCACAGAAGG AGAGCCTCTG 
GCCTTGAGGT GTCACCCGTG GCAGAATAAG AAAGTGTACA ATGTGGCTTT CTATCGAAAT 
GGAGAATCCC TTGACTTTTC TCAAGGTTCA GAGGTCACCA TTCTGAAAAC CAACCTGAGT 
CACAGCGGCA TCTATCACTG CTCAGCCATG GGAAAAAAAC TCTTCAAGTC TGCAGGAGTG 
TCTGTCACCG TGAAAGAGCT ATTTGCCACA CCAGTGCTGA GAGTGTCCTT GTCATCTCCC 
TTCCCGGAGG GGAGTCTGGT CATCCTGAAC TGTGAGACAA GATTGTTCCT GCAGAGTCCT 
GGCTTACGGC TTTACTTCTC CTTCTATGTG GGCAGTAAGA TCCTGGAGGA CAGGAGCACA 
TCCTCCGAGT ACCACATACC AAGGGCTGAA AGGGAAGATG ATGGATCATA CTGGTGCGAG 
GTAGCCACGG AGGACGGCCG TGTCCTTAAG CGCAGCACCA AGTTGGAGCT ATTTGGTCCC 
CAGTCATCAG ATCCTGTCTG GTTTCACATC CTATTTTATC TGTCAGTGGG AATAATGTTT 
TTGGTGAACA CAGTTCTCTA TGTGAAAATA CACAGGCTGC AGAGAGAGAA AAAATACAAT 
TTAGAAGTCC CTTTGGTTTC TGAGAAGGGG AAGAAAGCAA CTTCCTTTCA GCAAGTTAGA 
AGCGATGACG TGTATGAAGA AGTAACAGCC ACTGTAAGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094306.1
CDS	16..1077
Translation	MWLLTTLLLWVPVGGQVVNATKAVVTLQPPWLSIFQEENVTLLCEGPHLGDSSTKWFINSTAIQISTPTYSILKASFKDSGEYKCQTGLSMPSDPVQLEIYRDWLLLQTSHRVLTEGEPLALRCHPWQNKKVYNVAFYRNGESLDFSQGSEVTILKTNLSHSGIYHCSAMGKKLFKSAGVSVTVKELFATPVLRVSLSSPFPEGSLVILNCETRLFLQSPGLRLYFSFYVGSKILEDRSTSSEYHIPRAEREDDGSYWCEVATEDGRVLKRSTKLELFGPQSSDPVWFHILFYLSVGIMFLVNTVLYVKIHRLQREKKYNLEVPLVSEKGKKATSFQQVRSDDVYEEVTATVR

Target ORF information:

RefSeq Version	NM_001100836.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Fc fragment of IgG receptor Ia (Fcgr1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100836.1

ORF Insert Sequence:

ATGTGGCTTC TAACGACTCT GCTACTTTGG GTTCCAGTTG GTGGGCAAGT AGTTAATGCC 
ACAAAGGCTG TGGTCACCTT GCAGCCCCCA TGGCTCAGCA TTTTCCAGGA GGAAAATGTC 
ACTTTGTTGT GTGAGGGACC TCACCTGGGA GACAGTTCCA CAAAGTGGTT TATCAACAGC 
ACAGCCATTC AGATCTCCAC ACCTACCTAT AGCATCCTCA AGGCCAGTTT CAAGGACAGT 
GGTGAATACA AGTGTCAGAC AGGTCTCTCA ATGCCAAGTG ACCCTGTGCA GTTAGAAATC 
TACAGAGATT GGCTGCTACT CCAGACCTCC CACAGAGTCC TCACAGAAGG AGAGCCTCTG 
GCCTTGAGGT GTCACCCGTG GCAGAATAAG AAAGTGTACA ATGTGGCTTT CTATCGAAAT 
GGAGAATCCC TTGACTTTTC TCAAGGTTCA GAGGTCACCA TTCTGAAAAC CAACCTGAGT 
CACAGCGGCA TCTATCACTG CTCAGCCATG GGAAAAAAAC TCTTCAAGTC TGCAGGAGTG 
TCTGTCACCG TGAAAGAGCT ATTTGCCACA CCAGTGCTGA GAGTGTCCTT GTCATCTCCC 
TTCCCGGAGG GGAGTCTGGT CATCCTGAAC TGTGAGACAA GATTGTTCCT GCAGAGTCCT 
GGCTTACGGC TTTACTTCTC CTTCTATGTG GGCAGTAAGA TCCTGGAGGA CAGGAGCACA 
TCCTCCGAGT ACCACATACC AAGGGCTGAA AGGGAAGATG ATGGATCATA CTGGTGCGAG 
GTAGCCACGG AGGACGGCCG TGTCCTTAAG CGCAGCACCA AGTTGGAGCT ATTTGGTCCC 
CAGTCATCAG ATCCTGTCTG GTTTCACATC CTATTTTATC TGTCAGTGGG AATAATGTTT 
TTGGTGAACA CAGTTCTCTA TGTGAAAATA CACAGGCTGC AGAGAGAGAA AAAATACAAT 
TTAGAAGTCC CTTTGGTTTC TGAGAAGGGG AAGAAAGCAA CTTCCTTTCA GCAAGTTAGA 
AGCGATGACG TGTATGAAGA AGTAACAGCC ACTGTAAGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ovariectomy and subsequent treatment with estrogen receptor agonists tune the innate immune system of the hippocampus in middle-aged female rats.
PloS one9(2)e88540(2014)
Sárvári M,Kalló I,Hrabovszky E,Solymosi N,Liposits Z

Neuron-derived IgG protects dopaminergic neurons from insult by 6-OHDA and activates microglia through the FcγR I and TLR4 pathways.
The international journal of biochemistry & cell biology45(8)1911-20(2013 Aug)
Zhang J,Niu N,Wang M,McNutt MA,Zhang D,Zhang B,Lu S,Liu Y,Liu Z

Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association27(8)3149-55(2012 Aug)
Fet NG,Fiebeler A,Klinge U,Park JK,Barth S,Thepen T,Tolba RH

FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.
Blood114(15)3316-24(2009 Oct)
Serezani CH,Aronoff DM,Sitrin RG,Peters-Golden M

Delay of LPS-induced acute lung injury resolution by soluble immune complexes is neutrophil dependent.
Shock (Augusta, Ga.)32(3)276-85(2009 Sep)
Wu CL,Lin LY,Yeh HM,Chan MC,Yang CH,Hsueh CM

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Fcgr1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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