Fcgr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fcgr1
Entrez Gene ID	14129
Full Name	Fc receptor, IgG, high affinity I
Synonyms	AI323638,AV092959,CD64,FcgammaRI,IGGHAFC
General protein information	Preferred Names Fc receptor, IgG, high affinity I Names high affinity immunoglobulin gamma Fc receptor I IgG high affinity Fc receptor fc-gamma RI fcRI igG Fc receptor I
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3 F2.1\|3 41.72 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010186.5	NP_034316.1	high affinity immunoglobulin gamma Fc receptor I precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FCGR1A	XP_001165641.1
Homo sapiens (human)	FCGR1A	NP_000557.1
Canis lupus familiaris (dog)	FCGR1A	NP_001002976.1
Bos taurus (cattle)	FCGR1A	NP_776963.1
Rattus norvegicus (Norway rat)	Fcgr1a	NP_001094306.1
Mus musculus (house mouse)	Fcgr1	NP_034316.1

Gene Ontology
Bibliography

Related articles in PubMed

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.
Van Hove H, Martens L, Scheyltjens I, De Vlaminck K, Pombo Antunes AR, De Prijck S, Vandamme N, De Schepper S, Van Isterdael G, Scott CL, Aerts J, Berx G, Boeckxstaens GE, Vandenbroucke RE, Vereecke L, Moechars D, Guilliams M, Van Ginderachter JA, Saeys Y, Movahedi K
Nature neuroscience22(6)1021-1035(2019 06)

Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.
Bánki Z, Werner R, Riepler L, Rössler A, Müllauer B, Hegen V, Bayer W, Verbeek JS, Dittmer U, Stoiber H
Viruses11(2)(2019 02)

Single-cell transcriptomic analysis of mouse neocortical development.
Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ
Nature communications10(1)134(2019 01)

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages.
Scott CL, T'Jonck W, Martens L, Todorov H, Sichien D, Soen B, Bonnardel J, De Prijck S, Vandamme N, Cannoodt R, Saelens W, Vanneste B, Toussaint W, De Bleser P, Takahashi N, Vandenabeele P, Henri S, Pridans C, Hume DA, Lambrecht BN, De Baetselier P, Milling SWF, Van Ginderachter JA, Malissen B, Berx G, Beschin A, Saeys Y, Guilliams M
Immunity49(2)312-325.e5(2018 08)

Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.
Zhang H, Liu L, Li L
Journal of pharmacological sciences137(4)342-349(2018 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fcgr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fcgr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21767	NM_010186.5 Latest version!	Mus musculus Fc receptor, IgG, high affinity I (Fcgr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fcgr1 ( NM_010186.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034316.1 Mus musculus Fc receptor, IgG, high affinity I (Fcgr1), mRNA.

Price & Availability↑

CloneID	OMu21767
Clone ID Related Accession (Same CDS sequence)	NM_010186.5
Accession Version	NM_010186.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	high affinity immunoglobulin gamma Fc receptor I precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC093350.15. On Oct 19, 2007 this sequence version replaced NM_010186.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK033874.1, M31314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164143 [ECO:0000348] ##Evidence-Data-END##

ATGATTCTTA CCAGCTTTGG AGATGACATG TGGCTTCTAA CAACTCTGCT ACTTTGGGTT 
CCAGTCGGTG GGGAAGTGGT TAATGCCACC AAGGCTGTGA TCACCTTGCA GCCTCCATGG 
GTCAGTATTT TCCAGAAGGA AAATGTCACT TTATGGTGTG AGGGGCCTCA CCTGCCTGGA 
GACAGTTCCA CACAATGGTT TATCAACGGA ACAGCCGTTC AGATCTCCAC GCCTAGTTAT 
AGCATCCCAG AGGCCAGTTT TCAGGACAGT GGCGAATACA GGTGTCAGAT AGGTTCCTCA 
ATGCCAAGTG ACCCTGTGCA GTTGCAAATC CACAATGATT GGCTGCTACT CCAGGCCTCC 
CGCAGAGTCC TCACAGAAGG AGAACCCCTG GCCTTGAGGT GTCACGGATG GAAGAATAAA 
CTGGTGTACA ATGTGGTTTT CTATAGAAAT GGAAAATCCT TTCAGTTTTC TTCAGATTCG 
GAGGTCGCCA TTCTGAAAAC CAACCTGAGT CACAGCGGCA TCTACCACTG CTCAGGCACG 
GGAAGACACC GCTACACATC TGCAGGAGTG TCCATCACGG TGAAAGAGCT GTTTACCACG 
CCAGTGCTGA GAGCATCCGT GTCATCTCCC TTCCCGGAGG GGAGTCTGGT CACCCTGAAC 
TGTGAGACGA ATTTGCTCCT GCAGAGACCC GGCTTACAGC TTCACTTCTC CTTCTACGTG 
GGCAGCAAGA TCCTGGAGTA CAGGAACACA TCCTCAGAGT ACCATATAGC AAGGGCGGAA 
AGAGAAGATG CTGGATTCTA CTGGTGTGAG GTAGCCACGG AGGACAGCAG TGTCCTTAAG 
CGCAGCCCTG AGTTGGAGCT CCAAGTGCTT GGTCCCCAGT CATCAGCTCC TGTCTGGTTT 
CACATCCTGT TTTATCTGTC AGTGGGAATA ATGTTTTCGT TGAACACGGT TCTCTATGTG 
AAAATACACA GGCTGCAGAG AGAGAAGAAA TACAACTTAG AAGTCCCTTT GGTTTCTGAG 
CAGGGAAAGA AAGCAAATTC CTTTCAGCAA GTTAGAAGCG ATGGCGTGTA TGAAGAAGTA 
ACAGCCACTG CGAGCCAGAC CACACCAAAA GAAGCGCCCG ATGGACCTCG AAGCTCAGTG 
GGTGACTGTG GACCCGAGCA GCCTGAACCC CTTCCTCCCA GTGACAGTAC TGGGGCACAA 
ACTTCCCAAA GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034316.1
CDS	8..1222
Translation	MILTSFGDDMWLLTTLLLWVPVGGEVVNATKAVITLQPPWVSIFQKENVTLWCEGPHLPGDSSTQWFINGTAVQISTPSYSIPEASFQDSGEYRCQIGSSMPSDPVQLQIHNDWLLLQASRRVLTEGEPLALRCHGWKNKLVYNVVFYRNGKSFQFSSDSEVAILKTNLSHSGIYHCSGTGRHRYTSAGVSITVKELFTTPVLRASVSSPFPEGSLVTLNCETNLLLQRPGLQLHFSFYVGSKILEYRNTSSEYHIARAEREDAGFYWCEVATEDSSVLKRSPELELQVLGPQSSAPVWFHILFYLSVGIMFSLNTVLYVKIHRLQREKKYNLEVPLVSEQGKKANSFQQVRSDGVYEEVTATASQTTPKEAPDGPRSSVGDCGPEQPEPLPPSDSTGAQTSQS

Target ORF information:

RefSeq Version	NM_010186.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus Fc receptor, IgG, high affinity I (Fcgr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010186.5

ORF Insert Sequence:

ATGATTCTTA CCAGCTTTGG AGATGACATG TGGCTTCTAA CAACTCTGCT ACTTTGGGTT 
CCAGTCGGTG GGGAAGTGGT TAATGCCACC AAGGCTGTGA TCACCTTGCA GCCTCCATGG 
GTCAGTATTT TCCAGAAGGA AAATGTCACT TTATGGTGTG AGGGGCCTCA CCTGCCTGGA 
GACAGTTCCA CACAATGGTT TATCAACGGA ACAGCCGTTC AGATCTCCAC GCCTAGTTAT 
AGCATCCCAG AGGCCAGTTT TCAGGACAGT GGCGAATACA GGTGTCAGAT AGGTTCCTCA 
ATGCCAAGTG ACCCTGTGCA GTTGCAAATC CACAATGATT GGCTGCTACT CCAGGCCTCC 
CGCAGAGTCC TCACAGAAGG AGAACCCCTG GCCTTGAGGT GTCACGGATG GAAGAATAAA 
CTGGTGTACA ATGTGGTTTT CTATAGAAAT GGAAAATCCT TTCAGTTTTC TTCAGATTCG 
GAGGTCGCCA TTCTGAAAAC CAACCTGAGT CACAGCGGCA TCTACCACTG CTCAGGCACG 
GGAAGACACC GCTACACATC TGCAGGAGTG TCCATCACGG TGAAAGAGCT GTTTACCACG 
CCAGTGCTGA GAGCATCCGT GTCATCTCCC TTCCCGGAGG GGAGTCTGGT CACCCTGAAC 
TGTGAGACGA ATTTGCTCCT GCAGAGACCC GGCTTACAGC TTCACTTCTC CTTCTACGTG 
GGCAGCAAGA TCCTGGAGTA CAGGAACACA TCCTCAGAGT ACCATATAGC AAGGGCGGAA 
AGAGAAGATG CTGGATTCTA CTGGTGTGAG GTAGCCACGG AGGACAGCAG TGTCCTTAAG 
CGCAGCCCTG AGTTGGAGCT CCAAGTGCTT GGTCCCCAGT CATCAGCTCC TGTCTGGTTT 
CACATCCTGT TTTATCTGTC AGTGGGAATA ATGTTTTCGT TGAACACGGT TCTCTATGTG 
AAAATACACA GGCTGCAGAG AGAGAAGAAA TACAACTTAG AAGTCCCTTT GGTTTCTGAG 
CAGGGAAAGA AAGCAAATTC CTTTCAGCAA GTTAGAAGCG ATGGCGTGTA TGAAGAAGTA 
ACAGCCACTG CGAGCCAGAC CACACCAAAA GAAGCGCCCG ATGGACCTCG AAGCTCAGTG 
GGTGACTGTG GACCCGAGCA GCCTGAACCC CTTCCTCCCA GTGACAGTAC TGGGGCACAA 
ACTTCCCAAA GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.
Nature neuroscience22(6)1021-1035(2019 06)
Van Hove H,Martens L,Scheyltjens I,De Vlaminck K,Pombo Antunes AR,De Prijck S,Vandamme N,De Schepper S,Van Isterdael G,Scott CL,Aerts J,Berx G,Boeckxstaens GE,Vandenbroucke RE,Vereecke L,Moechars D,Guilliams M,Van Ginderachter JA,Saeys Y,Movahedi K

Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.
Viruses11(2)(2019 02)
Bánki Z,Werner R,Riepler L,Rössler A,Müllauer B,Hegen V,Bayer W,Verbeek JS,Dittmer U,Stoiber H

Single-cell transcriptomic analysis of mouse neocortical development.
Nature communications10(1)134(2019 01)
Loo L,Simon JM,Xing L,McCoy ES,Niehaus JK,Guo J,Anton ES,Zylka MJ

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages.
Immunity49(2)312-325.e5(2018 08)
Scott CL,T'Jonck W,Martens L,Todorov H,Sichien D,Soen B,Bonnardel J,De Prijck S,Vandamme N,Cannoodt R,Saelens W,Vanneste B,Toussaint W,De Bleser P,Takahashi N,Vandenabeele P,Henri S,Pridans C,Hume DA,Lambrecht BN,De Baetselier P,Milling SWF,Van Ginderachter JA,Malissen B,Berx G,Beschin A,Saeys Y,Guilliams M

Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.
Journal of pharmacological sciences137(4)342-349(2018 Aug)
Zhang H,Liu L,Li L

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Fcgr1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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