Padi3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Padi3
Entrez Gene ID	29520
Full Name	peptidyl arginine deiminase 3
Synonyms	Pdi3
General protein information	Preferred Names peptidyl arginine deiminase 3 Names protein-arginine deiminase type-3 peptidyl arginine deiminase, type 3 peptidyl arginine deiminase, type III peptidylarginine deiminase III protein-arginine deiminase type III
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	catalyzes deimination of arginine residues of proteins in the presence of calcium ions [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017230.2	NP_058926.1	protein-arginine deiminase type-3

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	PADI3	XP_001089024.1
Bos taurus (cattle)	PADI3	XP_003585850.2
Mus musculus (house mouse)	Padi3	NP_035190.3
Gallus gallus (chicken)	PADI3	NP_990374.1
Homo sapiens (human)	PADI3	NP_057317.2
Pan troglodytes (chimpanzee)	PADI3	XP_524563.1
Canis lupus familiaris (dog)	PADI3	XP_535391.2
Rattus norvegicus (Norway rat)	Padi3	NP_058926.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome.
Ü Basmanav FB, Cau L, Tafazzoli A, Méchin MC, Wolf S, Romano MT, Valentin F, Wiegmann H, Huchenq A, Kandil R, Garcia Bartels N, Kilic A, George S, Ralser DJ, Bergner S, Ferguson DJP, Oprisoreanu AM, Wehner M, Thiele H, Altmüller J, Nürnberg P, Swan D, Houniet D, Büchner A, Weibel L, Wagner N, Grimalt R, Bygum A, Serre G, Blume-Peytavi U, Sprecher E, Schoch S, Oji V, Hamm H, Farrant P, Simon M, Betz RC
American journal of human genetics99(6)1292-1304(2016 Dec)

Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin.
Ishigami A, Ohsawa T, Asaga H, Akiyama K, Kuramoto M, Maruyama N
Archives of biochemistry and biophysics407(1)25-31(2002 Nov)

Isolation and molecular cloning of epidermal- and hair follicle-specific peptidylarginine deiminase (type III) from rat.
Nishijyo T, Kawada A, Kanno T, Shiraiwa M, Takahara H
Journal of biochemistry121(5)868-75(1997 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Padi3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Padi3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12234	NM_017230.2 Latest version!	Rattus norvegicus peptidyl arginine deiminase 3 (Padi3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Padi3 ( NM_017230.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058926.1 Rattus norvegicus peptidyl arginine deiminase 3 (Padi3), mRNA.

Price & Availability↑

CloneID	ORa12234
Clone ID Related Accession (Same CDS sequence)	NM_017230.2
Accession Version	NM_017230.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Rattus norvegicus(Norway rat)
Product	protein-arginine deiminase type-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D88034.1. On Aug 31, 2012 this sequence version replaced NM_017230.1. ##Evidence-Data-START## Transcript exon combination :: D88034.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCTCTGC AGAGGACTGT ACGTGTATCC CTGGAACACC CAACCAGCGC TGTGTGTGTG 
GCAGGGGTTG AGACCATCGT GGACATTTAT GGGTCGGTTC CTGAGGGCAC AGACATGTTT 
GAGGTCTATG GGACACCGGG AGTGGACATC TACGTGTCTC CCAGCATGGA GAGGAACCGA 
GAGCGAGCTG ACACCAGGCG GTGGTGCTTC AACAAGGGGC TGGAGATCAT CGTGGTCATG 
AACTCTCCTA GCAATGACCT CAACGACAGT CACGTTCAAA TAGCTTACCA CTCCAGTCAC 
GAGCATTTGC CCCTGGCCTA TGCAGTACTC TACCTCACCT GTGTGGACAT CACCCTGGAC 
TGTGACATGA ACTGTGCTGA CCGGCAGGAC AGGAGCTTCG TGGATAAGAG GCAGTGGATG 
TGGGGACCTG ATGGGTACGG AGCCATCTTG CTGGTGAACT GTGATCGGGA CGAGGTCAGC 
TCTGATGCCC AAGATAACTG TGACCAATGT GTGCGCTGCC TGCAAGATCT GGAAGACATG 
TCCGTCATGG TCCTACGGAC CCAGGGCCCC GAATCTCTCT TTGACGACCA CAGGCTTATC 
CTCCACACCT CCAGCTGTGA TGCGGAGCGG GCACGGGTCT TCCACGTCTG TGGCCCCGAG 
GATTCCTGCG AAGCCTATAG GTGTGTTCTG GGCCCGGACC GGATGTCCTA TGAGGTACCC 
CGCCTGAAGG GCTATGAGGA GCGCTTCTAC GTGGAGGGCC TCTCCTTCCC TGATGCAGGC 
TTCCCAGGGA TCCTCTCCTT CCATATCACC CTGCTGGATG ACTCCAATGA GGACTACTCC 
GAGACCCCGA TCTTCACGGA CACAGTGGTG TTCCGAGTGG CACCCTGGAT CATGACGCCC 
AGCACCCTGC CACCCCTGGA GGTGTACGTG TGCCAGGTGA GGAATAACAC CTGCTTTGTG 
GAAGCTGTGG AGGAGCTGGC CAGGAAGGCA GGCTGCAAAC TCACCATCTG TCCTCAGGCA 
GAGAACCGCA ATGACCGATG GATCCAGGAT GAGATGGAGC TGGGGTACAC GCAGGCGCCA 
CACAAGACTT TGCCTGTGGT CTTTGATTCT CCGAGGAATG GGGAGCTGCA GGGTTTCCCT 
TACAAAAGGA TCCTGGGTCT AGATTTTGGC TACGTGACTC GAGAACCTCC AGACAGTTCT 
GTGAGCGGTC TGGACTCCTT TGGCAACCTG GAGGTCAGCC CGCCCGTGGT GGCCAATGGG 
AAGGAGTATC CACTGGGGAG GATTCTCATC GGGGGCAACC TGCCTGGGTC GAGAGGCCGC 
AGAGTTACCC AGGTGGTACG AGACTTCCTC CATGCCCAGA AGGTGCAACC TCTGGTGGAG 
TTGTTTGTGG ACTGGCTGGC TGTGGGCCAC GTGGATGAAT TTCTGAGCTT CGTCCCTGCA 
CCAGATGGAA AGGGCTTCCG GCTCCTCCTG GCCAGCCCTG GTGCCTGCTT CAGGCTATTC 
CAGGAAAAGC AGAAGTGGGG CCATGGCCGG TCCCTCCTTT TCGAGGGGGT CATTGGTGAC 
AGGCGGGTCC AGACCATCTC CATCAATCAG GTTCTTTCCA ACCAGAGCCT TATCAACTTT 
AATAAGTTTG CACAGAGCTG TATTGACTGG AACCGTGAGG TGCTGAAGCG GGAGCTAGGC 
CTGGGGGAGA GCGACATCAT TGACATCCCA CAGCTCTTCA AGTCGGAGAA GAGGAAGGCG 
GTGGCGTTCT TCCCGGACCT GGTGAACATG CTGGTACTGG GCAAGCACCT GGGCATCCCT 
AAGCCCTTCG GGCCCATCAT CAATGGCCGC TGCTGCCTGG AGGAGAAGGT GCGCTCCCTG 
CTGGAGCCGC TGGGTCTGCA CTGCACCTTC ATTGATGACT TCACACCGTA CCACATGCTG 
CACGGGGAGG TTCACTGTGG CACCAACGTG CGCCGGGAGC CCTTTGCCTT CAAGTGGTGG 
CACATGGTGC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058926.1
CDS	42..2036
Translation	MSLQRTVRVSLEHPTSAVCVAGVETIVDIYGSVPEGTDMFEVYGTPGVDIYVSPSMERNRERADTRRWCFNKGLEIIVVMNSPSNDLNDSHVQIAYHSSHEHLPLAYAVLYLTCVDITLDCDMNCADRQDRSFVDKRQWMWGPDGYGAILLVNCDRDEVSSDAQDNCDQCVRCLQDLEDMSVMVLRTQGPESLFDDHRLILHTSSCDAERARVFHVCGPEDSCEAYRCVLGPDRMSYEVPRLKGYEERFYVEGLSFPDAGFPGILSFHITLLDDSNEDYSETPIFTDTVVFRVAPWIMTPSTLPPLEVYVCQVRNNTCFVEAVEELARKAGCKLTICPQAENRNDRWIQDEMELGYTQAPHKTLPVVFDSPRNGELQGFPYKRILGLDFGYVTREPPDSSVSGLDSFGNLEVSPPVVANGKEYPLGRILIGGNLPGSRGRRVTQVVRDFLHAQKVQPLVELFVDWLAVGHVDEFLSFVPAPDGKGFRLLLASPGACFRLFQEKQKWGHGRSLLFEGVIGDRRVQTISINQVLSNQSLINFNKFAQSCIDWNREVLKRELGLGESDIIDIPQLFKSEKRKAVAFFPDLVNMLVLGKHLGIPKPFGPIINGRCCLEEKVRSLLEPLGLHCTFIDDFTPYHMLHGEVHCGTNVRREPFAFKWWHMVP

Target ORF information:

RefSeq Version	NM_017230.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus peptidyl arginine deiminase 3 (Padi3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017230.2

ORF Insert Sequence:

ATGTCTCTGC AGAGGACTGT ACGTGTATCC CTGGAACACC CAACCAGCGC TGTGTGTGTG 
GCAGGGGTTG AGACCATCGT GGACATTTAT GGGTCGGTTC CTGAGGGCAC AGACATGTTT 
GAGGTCTATG GGACACCGGG AGTGGACATC TACGTGTCTC CCAGCATGGA GAGGAACCGA 
GAGCGAGCTG ACACCAGGCG GTGGTGCTTC AACAAGGGGC TGGAGATCAT CGTGGTCATG 
AACTCTCCTA GCAATGACCT CAACGACAGT CACGTTCAAA TAGCTTACCA CTCCAGTCAC 
GAGCATTTGC CCCTGGCCTA TGCAGTACTC TACCTCACCT GTGTGGACAT CACCCTGGAC 
TGTGACATGA ACTGTGCTGA CCGGCAGGAC AGGAGCTTCG TGGATAAGAG GCAGTGGATG 
TGGGGACCTG ATGGGTACGG AGCCATCTTG CTGGTGAACT GTGATCGGGA CGAGGTCAGC 
TCTGATGCCC AAGATAACTG TGACCAATGT GTGCGCTGCC TGCAAGATCT GGAAGACATG 
TCCGTCATGG TCCTACGGAC CCAGGGCCCC GAATCTCTCT TTGACGACCA CAGGCTTATC 
CTCCACACCT CCAGCTGTGA TGCGGAGCGG GCACGGGTCT TCCACGTCTG TGGCCCCGAG 
GATTCCTGCG AAGCCTATAG GTGTGTTCTG GGCCCGGACC GGATGTCCTA TGAGGTACCC 
CGCCTGAAGG GCTATGAGGA GCGCTTCTAC GTGGAGGGCC TCTCCTTCCC TGATGCAGGC 
TTCCCAGGGA TCCTCTCCTT CCATATCACC CTGCTGGATG ACTCCAATGA GGACTACTCC 
GAGACCCCGA TCTTCACGGA CACAGTGGTG TTCCGAGTGG CACCCTGGAT CATGACGCCC 
AGCACCCTGC CACCCCTGGA GGTGTACGTG TGCCAGGTGA GGAATAACAC CTGCTTTGTG 
GAAGCTGTGG AGGAGCTGGC CAGGAAGGCA GGCTGCAAAC TCACCATCTG TCCTCAGGCA 
GAGAACCGCA ATGACCGATG GATCCAGGAT GAGATGGAGC TGGGGTACAC GCAGGCGCCA 
CACAAGACTT TGCCTGTGGT CTTTGATTCT CCGAGGAATG GGGAGCTGCA GGGTTTCCCT 
TACAAAAGGA TCCTGGGTCT AGATTTTGGC TACGTGACTC GAGAACCTCC AGACAGTTCT 
GTGAGCGGTC TGGACTCCTT TGGCAACCTG GAGGTCAGCC CGCCCGTGGT GGCCAATGGG 
AAGGAGTATC CACTGGGGAG GATTCTCATC GGGGGCAACC TGCCTGGGTC GAGAGGCCGC 
AGAGTTACCC AGGTGGTACG AGACTTCCTC CATGCCCAGA AGGTGCAACC TCTGGTGGAG 
TTGTTTGTGG ACTGGCTGGC TGTGGGCCAC GTGGATGAAT TTCTGAGCTT CGTCCCTGCA 
CCAGATGGAA AGGGCTTCCG GCTCCTCCTG GCCAGCCCTG GTGCCTGCTT CAGGCTATTC 
CAGGAAAAGC AGAAGTGGGG CCATGGCCGG TCCCTCCTTT TCGAGGGGGT CATTGGTGAC 
AGGCGGGTCC AGACCATCTC CATCAATCAG GTTCTTTCCA ACCAGAGCCT TATCAACTTT 
AATAAGTTTG CACAGAGCTG TATTGACTGG AACCGTGAGG TGCTGAAGCG GGAGCTAGGC 
CTGGGGGAGA GCGACATCAT TGACATCCCA CAGCTCTTCA AGTCGGAGAA GAGGAAGGCG 
GTGGCGTTCT TCCCGGACCT GGTGAACATG CTGGTACTGG GCAAGCACCT GGGCATCCCT 
AAGCCCTTCG GGCCCATCAT CAATGGCCGC TGCTGCCTGG AGGAGAAGGT GCGCTCCCTG 
CTGGAGCCGC TGGGTCTGCA CTGCACCTTC ATTGATGACT TCACACCGTA CCACATGCTG 
CACGGGGAGG TTCACTGTGG CACCAACGTG CGCCGGGAGC CCTTTGCCTT CAAGTGGTGG 
CACATGGTGC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome.
American journal of human genetics99(6)1292-1304(2016 Dec)
Ü Basmanav FB,Cau L,Tafazzoli A,Méchin MC,Wolf S,Romano MT,Valentin F,Wiegmann H,Huchenq A,Kandil R,Garcia Bartels N,Kilic A,George S,Ralser DJ,Bergner S,Ferguson DJP,Oprisoreanu AM,Wehner M,Thiele H,Altmüller J,Nürnberg P,Swan D,Houniet D,Büchner A,Weibel L,Wagner N,Grimalt R,Bygum A,Serre G,Blume-Peytavi U,Sprecher E,Schoch S,Oji V,Hamm H,Farrant P,Simon M,Betz RC

Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin.
Archives of biochemistry and biophysics407(1)25-31(2002 Nov)
Ishigami A,Ohsawa T,Asaga H,Akiyama K,Kuramoto M,Maruyama N

Isolation and molecular cloning of epidermal- and hair follicle-specific peptidylarginine deiminase (type III) from rat.
Journal of biochemistry121(5)868-75(1997 May)
Nishijyo T,Kawada A,Kanno T,Shiraiwa M,Takahara H

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Padi3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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