Sap18 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sap18
Entrez Gene ID	290284
Full Name	Sin3A associated protein 18
General protein information	Preferred Names Sin3A associated protein 18 Names histone deacetylase complex subunit SAP18 Sin3-associated polypeptide 18 Sin3A-associated protein, 18kDa sin3-associated polypeptide, 18kDa
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033685.2	NP_001028857.2	histone deacetylase complex subunit SAP18

Pathways from BioSystems

Homologies

Arabidopsis thaliana (thale cress)	SAP18	NP_566050.1
Mus musculus (house mouse)	Gm10094	NP_001135913.1
Rattus norvegicus (Norway rat)	Sap18	NP_001028857.2
Gallus gallus (chicken)	SAP18	NP_989643.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003036	XP_311841.2
Homo sapiens (human)	SAP18	NP_005861.2
Pan troglodytes (chimpanzee)	SAP18	XP_509567.3
Mus musculus (house mouse)	Sap18	NP_033145.2
Drosophila melanogaster (fruit fly)	Bin1	NP_524377.1
Oryza sativa (rice)	Os02g0122000	NP_001045723.1
Canis lupus familiaris (dog)	SAP18	NP_001239090.1
Rattus norvegicus (Norway rat)	RGD1561590	XP_002727857.1
Danio rerio (zebrafish)	sap18	NP_957014.1
Xenopus tropicalis (tropical clawed frog)	sap18	NP_001016166.1
Macaca mulatta (Rhesus monkey)	SAP18	XP_001085342.2
Bos taurus (cattle)	SAP18	NP_001030544.2
Caenorhabditis elegans (roundworm)	CELE_C16C10.4	NP_497833.1

Gene Ontology
Bibliography

Related articles in PubMed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanhäusser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.
Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B
Molecular and cellular biology32(5)954-67(2012 Mar)

Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold.
Singh KK, Erkelenz S, Rattay S, Dehof AK, Hildebrandt A, Schulze-Osthoff K, Schaal H, Schwerk C
RNA (New York, N.Y.)16(12)2442-54(2010 Dec)

Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.
Tange TØ, Shibuya T, Jurica MS, Moore MJ
RNA (New York, N.Y.)11(12)1869-83(2005 Dec)

ASAP, a novel protein complex involved in RNA processing and apoptosis.
Schwerk C, Prasad J, Degenhardt K, Erdjument-Bromage H, White E, Tempst P, Kidd VJ, Manley JL, Lahti JM, Reinberg D
Molecular and cellular biology23(8)2981-90(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sap18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sap18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08560	NM_001033685.2 Latest version!	Rattus norvegicus Sin3A associated protein 18 (Sap18), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sap18 ( NM_001033685.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001028857.2 Rattus norvegicus Sin3A associated protein 18 (Sap18), mRNA.

Price & Availability↑

CloneID	ORa08560
Clone ID Related Accession (Same CDS sequence)	NM_001033685.2
Accession Version	NM_001033685.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Rattus norvegicus(Norway rat)
Product	histone deacetylase complex subunit SAP18
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DY316441.1, BC104706.1, CK357541.1 and AW888346.1. On Dec 3, 2008 this sequence version replaced NM_001033685.1. ##Evidence-Data-START## Transcript exon combination :: FQ234134.1, FQ237358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCGCCG CAGGGGTCGG AGGTCAGGGC GAGCGTCTCC CGGGCCGAAG GAGGAAGATG 
GCGGTGGAAT CGCGCGTTAC CCAGGAGGAA ATTAAGAAGG AGCCGGAGAA GCCGATCGAC 
CGCGAGAAGA CCTGCCCGCT GCTGCTGCGG GTCTTCACCA CCAACAACGG CCGCCACCAC 
CGAATGGACG AGTTCTCCCG CGGGAACGTG CCTTCGAGCG AGCTGCAGAT CTACACCTGG 
ATGGATGCAA CCTTGAAAGA ACTGACTAGT TTAGTAAAGG AAGTCTACCC AGAAGCCAGA 
AAGAAGGGCA CGCACTTCAA TTTTGCAATT GTTTTTATGG ATCTTAAAAG ACCTGGATAT 
CGAGTTAAAG AGATTGGCAG CACCATGTCT GGCAGGAAGG GCACTGATGA CTCCATGACC 
CTGCAGTCAC AGAAGTTCCA AATAGGGGAT TATTTGGACA TAGCCATCAC GCCTCCAAAT 
CGGGCACCAC CTTCGTCAGG GAGGATGAGA CCGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028857.2
CDS	4..522
Translation	MLAAGVGGQGERLPGRRRKMAVESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFMDLKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPPSSGRMRPY

Target ORF information:

RefSeq Version	NM_001033685.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Sin3A associated protein 18 (Sap18), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033685.2

ORF Insert Sequence:

ATGCTCGCCG CAGGGGTCGG AGGTCAGGGC GAGCGTCTCC CGGGCCGAAG GAGGAAGATG 
GCGGTGGAAT CGCGCGTTAC CCAGGAGGAA ATTAAGAAGG AGCCGGAGAA GCCGATCGAC 
CGCGAGAAGA CCTGCCCGCT GCTGCTGCGG GTCTTCACCA CCAACAACGG CCGCCACCAC 
CGAATGGACG AGTTCTCCCG CGGGAACGTG CCTTCGAGCG AGCTGCAGAT CTACACCTGG 
ATGGATGCAA CCTTGAAAGA ACTGACTAGT TTAGTAAAGG AAGTCTACCC AGAAGCCAGA 
AAGAAGGGCA CGCACTTCAA TTTTGCAATT GTTTTTATGG ATCTTAAAAG ACCTGGATAT 
CGAGTTAAAG AGATTGGCAG CACCATGTCT GGCAGGAAGG GCACTGATGA CTCCATGACC 
CTGCAGTCAC AGAAGTTCCA AATAGGGGAT TATTTGGACA TAGCCATCAC GCCTCCAAAT 
CGGGCACCAC CTTCGTCAGG GAGGATGAGA CCGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.
Molecular and cellular biology32(5)954-67(2012 Mar)
Michelle L,Cloutier A,Toutant J,Shkreta L,Thibault P,Durand M,Garneau D,Gendron D,Lapointe E,Couture S,Le Hir H,Klinck R,Elela SA,Prinos P,Chabot B

Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold.
RNA (New York, N.Y.)16(12)2442-54(2010 Dec)
Singh KK,Erkelenz S,Rattay S,Dehof AK,Hildebrandt A,Schulze-Osthoff K,Schaal H,Schwerk C

Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.
RNA (New York, N.Y.)11(12)1869-83(2005 Dec)
Tange TØ,Shibuya T,Jurica MS,Moore MJ

ASAP, a novel protein complex involved in RNA processing and apoptosis.
Molecular and cellular biology23(8)2981-90(2003 Apr)
Schwerk C,Prasad J,Degenhardt K,Erdjument-Bromage H,White E,Tempst P,Kidd VJ,Manley JL,Lahti JM,Reinberg D

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Sap18 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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