Mks1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mks1
Entrez Gene ID	287612
Full Name	Meckel syndrome, type 1
General protein information	Preferred Names Meckel syndrome, type 1 Names Meckel syndrome type 1 protein homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q26

mRNA and Protein(s)

mRNA	Protein	Name
XM_017597129.1	XP_017452618.1	Meckel syndrome type 1 protein homolog isoform X1
NM_001034917.2	NP_001030089.2	Meckel syndrome type 1 protein homolog

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Mks1	NP_001030089.2
Bos taurus (cattle)	LOC101905689	XP_005220007.1
Pan troglodytes (chimpanzee)	MKS1	XP_001172592.1
Mus musculus (house mouse)	Mks1	NP_001034773.2
Gallus gallus (chicken)	MKS1	XP_415705.3
Danio rerio (zebrafish)	mks1	NP_001070841.2
Xenopus tropicalis (tropical clawed frog)	mks1	NP_001039150.1
Canis lupus familiaris (dog)	MKS1	XP_003639341.1
Homo sapiens (human)	MKS1	NP_060247.2

Gene Ontology
Bibliography

Related articles in PubMed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Burnicka-Turek O, Steimle JD, Huang W, Felker L, Kamp A, Kweon J, Peterson M, Reeves RH, Maslen CL, Gruber PJ, Yang XH, Shendure J, Moskowitz IP
Human molecular genetics25(14)3011-3028(2016 07)

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Liu X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW
PLoS biology11(11)e1001720(2013 Nov)

Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome.
Wheway G, Abdelhamed Z, Natarajan S, Toomes C, Inglehearn C, Johnson CA
Developmental biology377(1)55-66(2013 May)

Founder mutations and genotype-phenotype correlations in Meckel-Gruber syndrome and associated ciliopathies.
Szymanska K, Berry I, Logan CV, Cousins SR, Lindsay H, Jafri H, Raashid Y, Malik-Sharif S, Castle B, Ahmed M, Bennett C, Carlton R, Johnson CA
Cilia1(1)18(2012 Oct)

A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain.
Chih B, Liu P, Chinn Y, Chalouni C, Komuves LG, Hass PE, Sandoval W, Peterson AS
Nature cell biology14(1)61-72(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mks1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mks1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa57247	XM_017597129.1 Latest version!	Rattus norvegicus Meckel syndrome, type 1 (Mks1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa08965	NM_001034917.2 Latest version!	Rattus norvegicus MKS transition zone complex subunit 1 (Mks1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mks1 ( XM_017597129.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452618.1 Rattus norvegicus Meckel syndrome, type 1 (Mks1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa57247
Clone ID Related Accession (Same CDS sequence)	XM_017597129.1
Accession Version	XM_017597129.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	Meckel syndrome type 1 protein homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGGCG GCGGCGCCAG GACAGGCGAG GGGGAGGGCA GCAAACTCAA GTCTCGAATC 
ATCACATGGG AGCCCTCAGA AGACTTCATC AGGAACAGCC ATGCTATTAA CACCCCTCTT 
CAGACAATGT ATATCATGGC AGACCTGGGG CCGTATGGGA AGCTTGGCTA TAAGATACAT 
GAACATGTCC TCTGCGTCCT GAAGGTGGAT AGCAATGGAG TGATCACAGT GAAGCCCGAC 
TTCACTGGCA TCAAAGGACC CTACAGAATC GAGACTGAGG GAGAGAAGCA GGAACACACA 
TCTGCTTGGA AATACACAAT TGACAACGTG TCCTCCCTCG CACAACCAGA GGAGGAAGAG 
CGGGAGCAGC GTGTGTTCAA GGACCTTTAT GGCCGCCACA AGGAGTACCT CAGCAGCCTC 
GTGGGCACAG ACTTTGAGAT GATTGCCCCG GGTGCCCTCC GGCTCTTTGT GAATGGAGAG 
GTAGTCTCAG CCCGAGGCTA TGAGCATGAC AACCTCTATG TCCACTTCTT TGTGGAGCTG 
CCAGCTACGA ACTGGTCCAG CCCATCATTC CAGCAGCTCT CGGGAGTAAC CCAGACCTGT 
GTCACCAGAT CCCTGGGAAT GGACAAGGTG GCCTATTTCT CCTTTCCATT CACGTTTGAA 
GCCTTCTTCC TCCATGAGGA TGAATCAGAT GAATCACTCC CAGAGTGGCC CGTGCTCTAC 
TGTAAGGTCC TCTCACTGGA CTTCTGGCAG AGGTATCGTG TGGAAGGCTA CGGGGCTGTG 
GTGCTGCCTG TCACCCCAGG ATCACACACC TTGACTGCCT CCACGTGGAG GCCCATGGAG 
CTGGGCCTCG TGGCAGAGCT AAGGAGGTTC TTCATTGGTG GCTCCCTGGA GCTGGAGGAC 
CCATCCTATG TGAGGATACC AGGAACCTTC AAGGGGGAGC GGCTGAGCCG CTTTGGATTC 
CGCACTGAGA CGACGGGTAC GGTCACCTTC CGGCTGCACT GCCTGCAGCA GTCCCGGGCT 
TTCATGGAAT CGAACTCCCT CCGGAAACAA ATGAGGAGTG TGTTGGACCG TCTGGAAGGA 
TTCAGCCAGC AGAGTTCCAC ACACAACGTG CTAGAAGCAT TCCGTCGAGC CCGGCGCCGC 
ATGCAGGAGG CCCGAGAGAG CCTCCCCCAA GACCTTGTGA GCCCCACAGG GACGCTGGCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452618.1
CDS	149..1351
Translation	MSGGGARTGEGEGSKLKSRIITWEPSEDFIRNSHAINTPLQTMYIMADLGPYGKLGYKIHEHVLCVLKVDSNGVITVKPDFTGIKGPYRIETEGEKQEHTSAWKYTIDNVSSLAQPEEEEREQRVFKDLYGRHKEYLSSLVGTDFEMIAPGALRLFVNGEVVSARGYEHDNLYVHFFVELPATNWSSPSFQQLSGVTQTCVTRSLGMDKVAYFSFPFTFEAFFLHEDESDESLPEWPVLYCKVLSLDFWQRYRVEGYGAVVLPVTPGSHTLTASTWRPMELGLVAELRRFFIGGSLELEDPSYVRIPGTFKGERLSRFGFRTETTGTVTFRLHCLQQSRAFMESNSLRKQMRSVLDRLEGFSQQSSTHNVLEAFRRARRRMQEARESLPQDLVSPTGTLA

Target ORF information:

RefSeq Version	XM_017597129.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Meckel syndrome, type 1 (Mks1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597129.1

ORF Insert Sequence:

ATGTCAGGCG GCGGCGCCAG GACAGGCGAG GGGGAGGGCA GCAAACTCAA GTCTCGAATC 
ATCACATGGG AGCCCTCAGA AGACTTCATC AGGAACAGCC ATGCTATTAA CACCCCTCTT 
CAGACAATGT ATATCATGGC AGACCTGGGG CCGTATGGGA AGCTTGGCTA TAAGATACAT 
GAACATGTCC TCTGCGTCCT GAAGGTGGAT AGCAATGGAG TGATCACAGT GAAGCCCGAC 
TTCACTGGCA TCAAAGGACC CTACAGAATC GAGACTGAGG GAGAGAAGCA GGAACACACA 
TCTGCTTGGA AATACACAAT TGACAACGTG TCCTCCCTCG CACAACCAGA GGAGGAAGAG 
CGGGAGCAGC GTGTGTTCAA GGACCTTTAT GGCCGCCACA AGGAGTACCT CAGCAGCCTC 
GTGGGCACAG ACTTTGAGAT GATTGCCCCG GGTGCCCTCC GGCTCTTTGT GAATGGAGAG 
GTAGTCTCAG CCCGAGGCTA TGAGCATGAC AACCTCTATG TCCACTTCTT TGTGGAGCTG 
CCAGCTACGA ACTGGTCCAG CCCATCATTC CAGCAGCTCT CGGGAGTAAC CCAGACCTGT 
GTCACCAGAT CCCTGGGAAT GGACAAGGTG GCCTATTTCT CCTTTCCATT CACGTTTGAA 
GCCTTCTTCC TCCATGAGGA TGAATCAGAT GAATCACTCC CAGAGTGGCC CGTGCTCTAC 
TGTAAGGTCC TCTCACTGGA CTTCTGGCAG AGGTATCGTG TGGAAGGCTA CGGGGCTGTG 
GTGCTGCCTG TCACCCCAGG ATCACACACC TTGACTGCCT CCACGTGGAG GCCCATGGAG 
CTGGGCCTCG TGGCAGAGCT AAGGAGGTTC TTCATTGGTG GCTCCCTGGA GCTGGAGGAC 
CCATCCTATG TGAGGATACC AGGAACCTTC AAGGGGGAGC GGCTGAGCCG CTTTGGATTC 
CGCACTGAGA CGACGGGTAC GGTCACCTTC CGGCTGCACT GCCTGCAGCA GTCCCGGGCT 
TTCATGGAAT CGAACTCCCT CCGGAAACAA ATGAGGAGTG TGTTGGACCG TCTGGAAGGA 
TTCAGCCAGC AGAGTTCCAC ACACAACGTG CTAGAAGCAT TCCGTCGAGC CCGGCGCCGC 
ATGCAGGAGG CCCGAGAGAG CCTCCCCCAA GACCTTGTGA GCCCCACAGG GACGCTGGCC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mks1 ( NM_001034917.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001030089.2 Rattus norvegicus MKS transition zone complex subunit 1 (Mks1), mRNA.

Price & Availability↑

CloneID	ORa08965
Clone ID Related Accession (Same CDS sequence)	NM_001034917.2
Accession Version	NM_001034917.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	Meckel syndrome type 1 protein homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN948264.1 and BC099806.1. On Sep 29, 2009 this sequence version replaced NM_001034917.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC099806.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAAG CCGTCTGGAG CACTGACACC GGCGAGGCCG TGTATCGCTC CCGGGACCCC 
GTGCGCAACC TGCGCCTCCG AGTTCATCTG CAAAGAATCA CATCAAGCAA CTTCCTTCAT 
TACCAGCCTG CTGCCCAGAT GGGGAAGGAC CTCATAGACT TGGCCACTTT TAAGCCTCCT 
CAAGCTGCTA GTGGACACCG CCCTGATGAA GAAGAGGAGG AAGAAGTTAT AATTGGGTGG 
CAGGAGAAGC TGTTTAGCCA GTTTGAAGTT GACCTGTACC AAAATGAATC CGCGTGTCAG 
AGCCCATTAG ATCATCAGTA CCGCCAAGAG GTCCTGAAGC TGGAGAATTC TGGTGGCAGG 
AAAAACCGGC GAATCTTCAC TTACACCGAC TCGGATAGAT ACACCGACTT AGAAGAGTAC 
TGTCAGAAGA TAACCACTTC AGCCGGCGAG GCACCATCGT TTCTGGTTGA GCGGATGGCG 
AATGTCAGGC GGCGGCGCCA GGACAGGCGA GGGGTGGAGG GCAGCAAACT CAAGTCTCGA 
ATCATCACAT GGGAGCCCTC AGAAGACTTC ATCAGGAACA GCCATGCTAT TAACACCCCT 
CTTCAGACAA TGTATATCAT GGCAGACCTG GGGCCGTATG GGAAGCTTGG CTATAAGATA 
CATGAACATG TCCTCTGCGT CCTGAAGGTG GATAGCAATG GAGTGATCAC AGTGAAGCCC 
GACTTCACTG GCATCAAAGG ACCCTACAGA ATCGAGACTG AGGGAGAGAA GCAGGAACAC 
ACATCTGCTT GGAAATACAC AATTGACAAC GTGTCCTCCC TCGCACAACC AGAGGAGGAA 
GAGCGGGAGC AGCGTGTGTT CAAGGACCTT TATGGCCGCC ACAAGGAGTA CCTCAGCAGC 
CTCGTGGGCA CAGACTTTGA GATGATTGCC CCGGGTGCCC TCCGGCTCTT TGTGAATGGA 
GAGGTAGTCT CAGCCCGAGG CTATGAGCAT GACAACCTCT ATGTCCACTT CTTTGTGGAG 
CTGCCAGCTA CGAACTGGTC CAGCCCATCA TTCCAGCAGC TCTCGGGAGT AACCCAGACC 
TGTGTCACCA GATCCCTGGG AATGGACAAG GTGGCCTATT TCTCCTTTCC ATTCACGTTT 
GAAGCCTTCT TCCTCCATGA GGATGAATCA GATGAATCAC TCCCAGAGTG GCCCGTGCTC 
TACTGTAAGG TCCTCTCACT GGACTTCTGG CAGAGGTATC GTGTGGAAGG CTACGGGGCT 
GTGGTGCTGC CTGTCACCCC AGGATCACAC ACCTTGACTG CCTCCACGTG GAGGCCCATG 
GAGCTGGGCC TCGTGGCAGA GCTAAGGAGG TTCTTCATTG GTGGCTCCCT GGAGCTGGAG 
GACCCATCCT ATGTGAGGAT ACCAGGAACC TTCAAGGGGG AGCGGCTGAG CCGCTTTGGA 
TTCCGCACTG AGACGACGGG TACGGTCACC TTCCGGCTGC ACTGCCTGCA GCAGTCCCGG 
GCTTTCATGG AATCGAACTC CCTCCGGAAA CAAATGAGGA GTGTGTTGGA CCGTCTGGAA 
GGATTCAGCC AGCAGAGTTC CACACACAAC GTGCTAGAAG CATTCCGTCG AGCCCGGCGC 
CGCATGCAGG AGGCCCGAGA GAGCCTCCCC CAAGACCTTG TGAGCCCCAC AGGGACGCTG 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030089.2
CDS	1..1686
Translation	MAEAVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAQMGKDLIDLATFKPPQAASGHRPDEEEEEEVIIGWQEKLFSQFEVDLYQNESACQSPLDHQYRQEVLKLENSGGRKNRRIFTYTDSDRYTDLEEYCQKITTSAGEAPSFLVERMANVRRRRQDRRGVEGSKLKSRIITWEPSEDFIRNSHAINTPLQTMYIMADLGPYGKLGYKIHEHVLCVLKVDSNGVITVKPDFTGIKGPYRIETEGEKQEHTSAWKYTIDNVSSLAQPEEEEREQRVFKDLYGRHKEYLSSLVGTDFEMIAPGALRLFVNGEVVSARGYEHDNLYVHFFVELPATNWSSPSFQQLSGVTQTCVTRSLGMDKVAYFSFPFTFEAFFLHEDESDESLPEWPVLYCKVLSLDFWQRYRVEGYGAVVLPVTPGSHTLTASTWRPMELGLVAELRRFFIGGSLELEDPSYVRIPGTFKGERLSRFGFRTETTGTVTFRLHCLQQSRAFMESNSLRKQMRSVLDRLEGFSQQSSTHNVLEAFRRARRRMQEARESLPQDLVSPTGTLA

Target ORF information:

RefSeq Version	NM_001034917.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MKS transition zone complex subunit 1 (Mks1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034917.2

ORF Insert Sequence:

ATGGCGGAAG CCGTCTGGAG CACTGACACC GGCGAGGCCG TGTATCGCTC CCGGGACCCC 
GTGCGCAACC TGCGCCTCCG AGTTCATCTG CAAAGAATCA CATCAAGCAA CTTCCTTCAT 
TACCAGCCTG CTGCCCAGAT GGGGAAGGAC CTCATAGACT TGGCCACTTT TAAGCCTCCT 
CAAGCTGCTA GTGGACACCG CCCTGATGAA GAAGAGGAGG AAGAAGTTAT AATTGGGTGG 
CAGGAGAAGC TGTTTAGCCA GTTTGAAGTT GACCTGTACC AAAATGAATC CGCGTGTCAG 
AGCCCATTAG ATCATCAGTA CCGCCAAGAG GTCCTGAAGC TGGAGAATTC TGGTGGCAGG 
AAAAACCGGC GAATCTTCAC TTACACCGAC TCGGATAGAT ACACCGACTT AGAAGAGTAC 
TGTCAGAAGA TAACCACTTC AGCCGGCGAG GCACCATCGT TTCTGGTTGA GCGGATGGCG 
AATGTCAGGC GGCGGCGCCA GGACAGGCGA GGGGTGGAGG GCAGCAAACT CAAGTCTCGA 
ATCATCACAT GGGAGCCCTC AGAAGACTTC ATCAGGAACA GCCATGCTAT TAACACCCCT 
CTTCAGACAA TGTATATCAT GGCAGACCTG GGGCCGTATG GGAAGCTTGG CTATAAGATA 
CATGAACATG TCCTCTGCGT CCTGAAGGTG GATAGCAATG GAGTGATCAC AGTGAAGCCC 
GACTTCACTG GCATCAAAGG ACCCTACAGA ATCGAGACTG AGGGAGAGAA GCAGGAACAC 
ACATCTGCTT GGAAATACAC AATTGACAAC GTGTCCTCCC TCGCACAACC AGAGGAGGAA 
GAGCGGGAGC AGCGTGTGTT CAAGGACCTT TATGGCCGCC ACAAGGAGTA CCTCAGCAGC 
CTCGTGGGCA CAGACTTTGA GATGATTGCC CCGGGTGCCC TCCGGCTCTT TGTGAATGGA 
GAGGTAGTCT CAGCCCGAGG CTATGAGCAT GACAACCTCT ATGTCCACTT CTTTGTGGAG 
CTGCCAGCTA CGAACTGGTC CAGCCCATCA TTCCAGCAGC TCTCGGGAGT AACCCAGACC 
TGTGTCACCA GATCCCTGGG AATGGACAAG GTGGCCTATT TCTCCTTTCC ATTCACGTTT 
GAAGCCTTCT TCCTCCATGA GGATGAATCA GATGAATCAC TCCCAGAGTG GCCCGTGCTC 
TACTGTAAGG TCCTCTCACT GGACTTCTGG CAGAGGTATC GTGTGGAAGG CTACGGGGCT 
GTGGTGCTGC CTGTCACCCC AGGATCACAC ACCTTGACTG CCTCCACGTG GAGGCCCATG 
GAGCTGGGCC TCGTGGCAGA GCTAAGGAGG TTCTTCATTG GTGGCTCCCT GGAGCTGGAG 
GACCCATCCT ATGTGAGGAT ACCAGGAACC TTCAAGGGGG AGCGGCTGAG CCGCTTTGGA 
TTCCGCACTG AGACGACGGG TACGGTCACC TTCCGGCTGC ACTGCCTGCA GCAGTCCCGG 
GCTTTCATGG AATCGAACTC CCTCCGGAAA CAAATGAGGA GTGTGTTGGA CCGTCTGGAA 
GGATTCAGCC AGCAGAGTTC CACACACAAC GTGCTAGAAG CATTCCGTCG AGCCCGGCGC 
CGCATGCAGG AGGCCCGAGA GAGCCTCCCC CAAGACCTTG TGAGCCCCAC AGGGACGCTG 
GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Human molecular genetics25(14)3011-3028(2016 07)
Burnicka-Turek O,Steimle JD,Huang W,Felker L,Kamp A,Kweon J,Peterson M,Reeves RH,Maslen CL,Gruber PJ,Yang XH,Shendure J,Moskowitz IP

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.
PLoS biology11(11)e1001720(2013 Nov)
Cui C,Chatterjee B,Lozito TP,Zhang Z,Francis RJ,Yagi H,Swanhart LM,Sanker S,Francis D,Yu Q,San Agustin JT,Puligilla C,Chatterjee T,Tansey T,Liu X,Kelley MW,Spiliotis ET,Kwiatkowski AV,Tuan R,Pazour GJ,Hukriede NA,Lo CW

Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome.
Developmental biology377(1)55-66(2013 May)
Wheway G,Abdelhamed Z,Natarajan S,Toomes C,Inglehearn C,Johnson CA

Founder mutations and genotype-phenotype correlations in Meckel-Gruber syndrome and associated ciliopathies.
Cilia1(1)18(2012 Oct)
Szymanska K,Berry I,Logan CV,Cousins SR,Lindsay H,Jafri H,Raashid Y,Malik-Sharif S,Castle B,Ahmed M,Bennett C,Carlton R,Johnson CA

A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain.
Nature cell biology14(1)61-72(2011 Dec)
Chih B,Liu P,Chinn Y,Chalouni C,Komuves LG,Hass PE,Sandoval W,Peterson AS

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Mks1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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