Pkm cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pkm
Entrez Gene ID	25630
Full Name	pyruvate kinase M1/2
Synonyms	PK,PKM12,Pk3,Pkm2
General protein information	Preferred Names pyruvate kinase M1/2 Names pyruvate kinase PKM M2 pyruvate kinase pyruvate kinase isozymes M1/M2 pyruvate kinase muscle isozyme pyruvate kinase, muscle
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24
Summary	M1 and M2 isozymes of pyruvate kinase; catalyzes the conversion of ATP and pyruvate to ADP and phosphoenolpyruvate in glycolysis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006243188.3	XP_006243250.2	pyruvate kinase PKM isoform X1
XM_017595480.1	XP_017450969.1	pyruvate kinase PKM isoform X3
NM_053297.2	NP_445749.1	pyruvate kinase PKM
XM_006243190.3	XP_006243252.1	pyruvate kinase PKM isoform X2

Pathways from BioSystems

Homologies

Schizosaccharomyces pombe (fission yeast)	pyk1	NP_594346.1
Homo sapiens (human)	PKM	NP_001193725.1
Gallus gallus (chicken)	PKM2	NP_990800.1
Drosophila melanogaster (fruit fly)	PyK	NP_524448.3
Arabidopsis thaliana (thale cress)	AT5G63680	NP_201173.1
Arabidopsis thaliana (thale cress)	AT5G08570	NP_196474.1
Kluyveromyces lactis	KLLA0F23397g	XP_456122.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004596	XP_315228.5
Magnaporthe oryzae (rice blast fungus)	MGG_08063	XP_003715015.1
Macaca mulatta (Rhesus monkey)	PKM	XP_001099473.2
Rattus norvegicus (Norway rat)	Pkm	NP_445749.1
Oryza sativa (rice)	Os04g0677500	NP_001054265.1
Neurospora crassa	NCU06075	XP_959838.1
Pan troglodytes (chimpanzee)	PKM	XP_003314790.1
Canis lupus familiaris (dog)	PKM	XP_005638614.1
Caenorhabditis elegans (roundworm)	pyk-1	NP_001251014.1
Caenorhabditis elegans (roundworm)	pyk-2	NP_001255515.1
Saccharomyces cerevisiae (baker's yeast)	CDC19	NP_009362.1
Eremothecium gossypii	AGOS_ADR368W	NP_984464.1
Bos taurus (cattle)	PKM	NP_001192656.1
Mus musculus (house mouse)	Pkm	NP_035229.2
Danio rerio (zebrafish)	pkma	NP_955365.1
Xenopus tropicalis (tropical clawed frog)	pkm	NP_001072532.1

Gene Ontology
Bibliography

Related articles in PubMed

SIRT 1 binding with PKM and NSE and modulate their acetylation and activities.
Zhang ZH, Zhang H, Wang YR, Liu XL, Huang H, Xu XH
Biochimica et biophysica acta. Proteins and proteomics1867(9)794-801(2019 09)

PKM2 Involved in Neuronal Apoptosis on Hypoxic-ischemic Encephalopathy in Neonatal Rats.
Wu Q, Ge W, Chen Y, Kong X, Xian H
Neurochemical research44(7)1602-1612(2019 Jul)

Alpha-synuclein induces microglial migration via PKM2-dependent glycolysis.
Qiao H, He X, Zhang Q, Yuan H, Wang D, Li L, Hui Y, Wu Z, Li W, Zhang N
International journal of biological macromolecules129601-607(2019 May)

Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions.
Bi YH, Han WQ, Li RF, Wang YJ, Du ZS, Wang XJ, Jiang Y
World journal of gastroenterology25(16)1936-1949(2019 Apr)

JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting With Pyruvate Kinase M2 in Endothelial Cells.
Boeckel JN, Derlet A, Glaser SF, Luczak A, Lucas T, Heumüller AW, Krüger M, Zehendner CM, Kaluza D, Doddaballapur A, Ohtani K, Treguer K, Dimmeler S
Arteriosclerosis, thrombosis, and vascular biology36(7)1425-33(2016 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pkm gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pkm cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09209	NM_053297.2 Latest version!	Rattus norvegicus pyruvate kinase M1/2 (Pkm), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa31246	XM_006243190.3 Latest version!	Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa62325	XM_006243188.3 Latest version!	Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa62326	XM_017595480.1 Latest version!	Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pkm ( NM_053297.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445749.1 Rattus norvegicus pyruvate kinase M1/2 (Pkm), mRNA.

Price & Availability↑

CloneID	ORa09209
Clone ID Related Accession (Same CDS sequence)	NM_053297.2
Accession Version	NM_053297.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	pyruvate kinase PKM
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X15800.1. On Aug 31, 2012 this sequence version replaced NM_053297.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X15800.1, FQ223721.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGCCCAAGC CAGACAGCGA AGCAGGGACT GCCTTCATTC AGACCCAGCA GCTCCATGCA 
GCCATGGCTG ACACCTTCCT GGAACACATG TGCCGCCTGG ACATTGACTC CGCACCCATC 
ACGGCCCGCA ACACTGGGAT CATCTGTACC ATTGGCCCTG CTTCCCGATC TGTGGAGATG 
CTGAAGGAGA TGATTAAGTC TGGGATGAAT GTGGCTCGGC TGAATTTCTC TCATGGAACC 
CATGAGTACC ATGCAGAGAC TATCAAGAAT GTCCGTGCAG CCACAGAAAG CTTTGCATCT 
GATCCCATTC TCTACCGACC TGTTGCGGTG GCTCTGGATA CAAAGGGACC TGAGATCCGG 
ACTGGACTCA TCAAGGGCAG CGGCACCGCA GAGGTGGAGC TGAAGAAGGG AGCCACACTG 
AAGATCACCC TGGACAACGC CTACATGGAG AAGTGCGATG AGAACATCCT GTGGCTGGAC 
TATAAGAACA TCTGCAAGGT GGTGGAGGTG GGCAGCAAGA TCTACGTGGA CGATGGGCTC 
ATCTCCCTGC AGGTGAAGGA GAAAGGTGCT GACTACCTGG TGACAGAAGT GGAAAATGGT 
GGCTCCTTGG GCAGCAAGAA GGGCGTGAAC CTGCCTGGTG CTGCTGTGGA CCTCCCTGCT 
GTGTCAGAAA AGGACATCCA GGACCTGAAG TTTGGGGTGG AGCAGGACGT GGACATGGTG 
TTTGCGTCTT TCATCCGCAA GGCGGCTGAC GTGCATGAGG TTAGGAAGGT CCTGGGAGAG 
AAGGGCAAGA ACATCAAGAT CATCAGCAAA ATCGAGAACC ATGAAGGTGT CCGCAGGTTT 
GATGAGATTT TGGAGGCCAG CGATGGAATC ATGGTAGCTC GTGGTGACCT GGGCATTGAG 
ATTCCGGCAG AGAAGGTCTT CCTAGCTCAG AAGATGATGA TTGGACGATG CAACCGAGCT 
GGGAAGCCAG TCATCTGCGC CACCCAGATG CTGGAGAGCA TGATCAAGAA GCCACGCCCC 
ACCCGTGCTG AAGGCAGTGA CGTGGCCAAT GCAGTCCTAG ATGGAGCTGA CTGCATCATG 
CTGTCCGGAG AAACAGCCAA AGGGGACTAC CCTCTGGAGG CTGTTCGCAT GCAGCACCTG 
ATAGCTCGAG AGGCTGAGGC AGCCGTGTTC CACCGCCTGC TGTTTGAAGA GCTTGCGCGA 
GCCTCCAGTC AATCCACAGA CCCCCTGGAG GCCATGGCCA TGGGCAGCGT GGAGGCCTCT 
TATAAATGTT TAGCAGCAGC TTTGATAGTT CTGACGGAGT CCGGCAGGAG TGCTCACCAA 
GTGGCCCGGT ACCGCCCAAG GGCTCCTATC ATTGCTGTGA CACGCAATCC CCAGACAGCC 
CGCCAGGCCC ATCTGTACCG TGGCATCTTC CCTGTGCTGT GTAAGGATGC CGTACTGGAT 
GCCTGGGCTG AGGACGTTGA TCTTCGTGTG AACTTGGCCA TGAATGTTGG CAAGGCCCGA 
GGCTTCTTCA AGAAGGGAGA TGTGGTCATT GTGCTGACTG GATGGCGCCC TGGCTCTGGC 
TTCACCAACA CCATGCGTGT AGTGCCTGTA CCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445749.1
CDS	83..1678
Translation	MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP

Target ORF information:

RefSeq Version	NM_053297.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pyruvate kinase M1/2 (Pkm), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053297.2

ORF Insert Sequence:

ATGCCCAAGC CAGACAGCGA AGCAGGGACT GCCTTCATTC AGACCCAGCA GCTCCATGCA 
GCCATGGCTG ACACCTTCCT GGAACACATG TGCCGCCTGG ACATTGACTC CGCACCCATC 
ACGGCCCGCA ACACTGGGAT CATCTGTACC ATTGGCCCTG CTTCCCGATC TGTGGAGATG 
CTGAAGGAGA TGATTAAGTC TGGGATGAAT GTGGCTCGGC TGAATTTCTC TCATGGAACC 
CATGAGTACC ATGCAGAGAC TATCAAGAAT GTCCGTGCAG CCACAGAAAG CTTTGCATCT 
GATCCCATTC TCTACCGACC TGTTGCGGTG GCTCTGGATA CAAAGGGACC TGAGATCCGG 
ACTGGACTCA TCAAGGGCAG CGGCACCGCA GAGGTGGAGC TGAAGAAGGG AGCCACACTG 
AAGATCACCC TGGACAACGC CTACATGGAG AAGTGCGATG AGAACATCCT GTGGCTGGAC 
TATAAGAACA TCTGCAAGGT GGTGGAGGTG GGCAGCAAGA TCTACGTGGA CGATGGGCTC 
ATCTCCCTGC AGGTGAAGGA GAAAGGTGCT GACTACCTGG TGACAGAAGT GGAAAATGGT 
GGCTCCTTGG GCAGCAAGAA GGGCGTGAAC CTGCCTGGTG CTGCTGTGGA CCTCCCTGCT 
GTGTCAGAAA AGGACATCCA GGACCTGAAG TTTGGGGTGG AGCAGGACGT GGACATGGTG 
TTTGCGTCTT TCATCCGCAA GGCGGCTGAC GTGCATGAGG TTAGGAAGGT CCTGGGAGAG 
AAGGGCAAGA ACATCAAGAT CATCAGCAAA ATCGAGAACC ATGAAGGTGT CCGCAGGTTT 
GATGAGATTT TGGAGGCCAG CGATGGAATC ATGGTAGCTC GTGGTGACCT GGGCATTGAG 
ATTCCGGCAG AGAAGGTCTT CCTAGCTCAG AAGATGATGA TTGGACGATG CAACCGAGCT 
GGGAAGCCAG TCATCTGCGC CACCCAGATG CTGGAGAGCA TGATCAAGAA GCCACGCCCC 
ACCCGTGCTG AAGGCAGTGA CGTGGCCAAT GCAGTCCTAG ATGGAGCTGA CTGCATCATG 
CTGTCCGGAG AAACAGCCAA AGGGGACTAC CCTCTGGAGG CTGTTCGCAT GCAGCACCTG 
ATAGCTCGAG AGGCTGAGGC AGCCGTGTTC CACCGCCTGC TGTTTGAAGA GCTTGCGCGA 
GCCTCCAGTC AATCCACAGA CCCCCTGGAG GCCATGGCCA TGGGCAGCGT GGAGGCCTCT 
TATAAATGTT TAGCAGCAGC TTTGATAGTT CTGACGGAGT CCGGCAGGAG TGCTCACCAA 
GTGGCCCGGT ACCGCCCAAG GGCTCCTATC ATTGCTGTGA CACGCAATCC CCAGACAGCC 
CGCCAGGCCC ATCTGTACCG TGGCATCTTC CCTGTGCTGT GTAAGGATGC CGTACTGGAT 
GCCTGGGCTG AGGACGTTGA TCTTCGTGTG AACTTGGCCA TGAATGTTGG CAAGGCCCGA 
GGCTTCTTCA AGAAGGGAGA TGTGGTCATT GTGCTGACTG GATGGCGCCC TGGCTCTGGC 
TTCACCAACA CCATGCGTGT AGTGCCTGTA CCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pkm ( XM_006243190.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006243252.1 Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa31246
Clone ID Related Accession (Same CDS sequence)	XM_006243190.3
Accession Version	XM_006243190.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	pyruvate kinase PKM isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006243190.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTCAAC CTTTCAACTT AGAGGCTTTT GAGAGAATTT TCTTCCTTGG CTCTTCAGGG 
CAGAGCATAC TCAGCTCTGA GCTGTCTTTC CAAGTGGGGC CATCAAGCCA ATCTGGGTCA 
AAAAAACGGC AATATGTCAA CAGAAGCCCA GACCCAGAGA TCCAAAGGAT CTCAGAAACC 
ATGCCCAAGC CAGACAGCGA AGCAGGGACT GCCTTCATTC AGACCCAGCA GCTCCATGCA 
GCCATGGCTG ACACCTTCCT GGAACACATG TGCCGCCTGG ACATTGACTC CGCACCCATC 
ACGGCCCGCA ACACTGGGAT CATCTGTACC ATTGGCCCTG CTTCCCGATC TGTGGAGATG 
CTGAAGGAGA TGATTAAGTC TGGGATGAAT GTGGCTCGGC TGAATTTCTC TCATGGAACC 
CATGAGTACC ATGCAGAGAC TATCAAGAAT GTCCGTGCAG CCACAGAAAG CTTTGCATCT 
GATCCCATTC TCTACCGACC TGTTGCGGTG GCTCTGGATA CAAAGGGACC TGAGATCCGG 
ACTGGACTCA TCAAGGGCAG CGGCACCGCA GAGGTGGAGC TGAAGAAGGG AGCCACACTG 
AAGATCACCC TGGACAACGC CTACATGGAG AAGTGCGACG AGAACATCCT GTGGCTGGAC 
TATAAGAACA TCTGCAAGGT GGTGGAGGTG GGCAGCAAGA TCTACGTGGA CGATGGGCTC 
ATCTCCCTGC AGGTGAAGGA GAAAGGTGCT GACTACCTGG TGACAGAAGT GGAAAATGGT 
GGCTCCTTGG GCAGCAAGAA GGGCGTGAAC CTGCCTGGTG CTGCTGTGGA CCTCCCTGCT 
GTGTCAGAAA AGGACATCCA GGACCTGAAG TTTGGGGTGG AGCAGGACGT GGACATGGTG 
TTTGCGTCTT TCATCCGCAA GGCGGCTGAC GTGCATGAGG TTAGGAAGGT CCTGGGAGAG 
AAGGGCAAGA ACATCAAGAT CATCAGCAAA ATCGAGAACC ATGAAGGTGT CCGCAGGTTT 
GATGAGATTT TGGAGGCCAG CGATGGAATC ATGGTAGCTC GTGGTGACCT GGGCATTGAG 
ATTCCGGCAG AGAAGGTCTT CCTAGCTCAG AAGATGATGA TTGGACGATG CAACCGAGCT 
GGGAAGCCAG TCATCTGCGC CACCCAGATG CTGGAGAGCA TGATCAAGAA GCCACGCCCC 
ACCCGTGCTG AAGGCAGTGA CGTGGCCAAT GCAGTCCTAG ATGGAGCTGA CTGCATCATG 
CTGTCCGGAG AAACAGCCAA AGGGGACTAC CCTCTGGAGG CTGTTCGCAT GCAGCACCTG 
ATAGCTCGAG AGGCTGAGGC AGCCGTGTTC CACCGCCTGC TGTTTGAAGA GCTTGCGCGA 
GCCTCCAGTC AATCCACAGA CCCCCTGGAG GCCATGGCCA TGGGCAGCGT GGAGGCCTCT 
TATAAATGTT TAGCAGCAGC TTTGATAGTT CTGACGGAGT CCGGCAGGAG TGCTCACCAA 
GTGGCCCGGT ACCGCCCAAG GGCTCCTATC ATTGCTGTGA CACGCAATCC CCAGACAGCC 
CGCCAGGCCC ATCTGTACCG TGGCATCTTC CCTGTGCTGT GTAAGGATGC CGTACTGGAT 
GCCTGGGCTG AGGACGTTGA TCTTCGTGTG AACTTGGCCA TGAATGTTGG CAAGGCCCGA 
GGCTTCTTCA AGAAGGGAGA TGTGGTCATT GTGCTGACTG GATGGCGCCC TGGCTCTGGC 
TTCACCAACA CCATGCGTGT AGTGCCTGTA CCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006243252.1
CDS	21..1796
Translation	MTQPFNLEAFERIFFLGSSGQSILSSELSFQVGPSSQSGSKKRQYVNRSPDPEIQRISETMPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP

Target ORF information:

RefSeq Version	XM_006243190.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006243190.3

ORF Insert Sequence:

ATGACTCAAC CTTTCAACTT AGAGGCTTTT GAGAGAATTT TCTTCCTTGG CTCTTCAGGG 
CAGAGCATAC TCAGCTCTGA GCTGTCTTTC CAAGTGGGGC CATCAAGCCA ATCTGGGTCA 
AAAAAACGGC AATATGTCAA CAGAAGCCCA GACCCAGAGA TCCAAAGGAT CTCAGAAACC 
ATGCCCAAGC CAGACAGCGA AGCAGGGACT GCCTTCATTC AGACCCAGCA GCTCCATGCA 
GCCATGGCTG ACACCTTCCT GGAACACATG TGCCGCCTGG ACATTGACTC CGCACCCATC 
ACGGCCCGCA ACACTGGGAT CATCTGTACC ATTGGCCCTG CTTCCCGATC TGTGGAGATG 
CTGAAGGAGA TGATTAAGTC TGGGATGAAT GTGGCTCGGC TGAATTTCTC TCATGGAACC 
CATGAGTACC ATGCAGAGAC TATCAAGAAT GTCCGTGCAG CCACAGAAAG CTTTGCATCT 
GATCCCATTC TCTACCGACC TGTTGCGGTG GCTCTGGATA CAAAGGGACC TGAGATCCGG 
ACTGGACTCA TCAAGGGCAG CGGCACCGCA GAGGTGGAGC TGAAGAAGGG AGCCACACTG 
AAGATCACCC TGGACAACGC CTACATGGAG AAGTGCGACG AGAACATCCT GTGGCTGGAC 
TATAAGAACA TCTGCAAGGT GGTGGAGGTG GGCAGCAAGA TCTACGTGGA CGATGGGCTC 
ATCTCCCTGC AGGTGAAGGA GAAAGGTGCT GACTACCTGG TGACAGAAGT GGAAAATGGT 
GGCTCCTTGG GCAGCAAGAA GGGCGTGAAC CTGCCTGGTG CTGCTGTGGA CCTCCCTGCT 
GTGTCAGAAA AGGACATCCA GGACCTGAAG TTTGGGGTGG AGCAGGACGT GGACATGGTG 
TTTGCGTCTT TCATCCGCAA GGCGGCTGAC GTGCATGAGG TTAGGAAGGT CCTGGGAGAG 
AAGGGCAAGA ACATCAAGAT CATCAGCAAA ATCGAGAACC ATGAAGGTGT CCGCAGGTTT 
GATGAGATTT TGGAGGCCAG CGATGGAATC ATGGTAGCTC GTGGTGACCT GGGCATTGAG 
ATTCCGGCAG AGAAGGTCTT CCTAGCTCAG AAGATGATGA TTGGACGATG CAACCGAGCT 
GGGAAGCCAG TCATCTGCGC CACCCAGATG CTGGAGAGCA TGATCAAGAA GCCACGCCCC 
ACCCGTGCTG AAGGCAGTGA CGTGGCCAAT GCAGTCCTAG ATGGAGCTGA CTGCATCATG 
CTGTCCGGAG AAACAGCCAA AGGGGACTAC CCTCTGGAGG CTGTTCGCAT GCAGCACCTG 
ATAGCTCGAG AGGCTGAGGC AGCCGTGTTC CACCGCCTGC TGTTTGAAGA GCTTGCGCGA 
GCCTCCAGTC AATCCACAGA CCCCCTGGAG GCCATGGCCA TGGGCAGCGT GGAGGCCTCT 
TATAAATGTT TAGCAGCAGC TTTGATAGTT CTGACGGAGT CCGGCAGGAG TGCTCACCAA 
GTGGCCCGGT ACCGCCCAAG GGCTCCTATC ATTGCTGTGA CACGCAATCC CCAGACAGCC 
CGCCAGGCCC ATCTGTACCG TGGCATCTTC CCTGTGCTGT GTAAGGATGC CGTACTGGAT 
GCCTGGGCTG AGGACGTTGA TCTTCGTGTG AACTTGGCCA TGAATGTTGG CAAGGCCCGA 
GGCTTCTTCA AGAAGGGAGA TGTGGTCATT GTGCTGACTG GATGGCGCCC TGGCTCTGGC 
TTCACCAACA CCATGCGTGT AGTGCCTGTA CCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pkm ( XM_006243188.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006243250.2 Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62325
Clone ID Related Accession (Same CDS sequence)	XM_006243188.3
Accession Version	XM_006243188.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	pyruvate kinase PKM isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006243188.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCAAGC CAGACAGCGA AGCAGGGACT GCCTTCATTC AGACCCAGCA GCTCCATGCA 
GCCATGGCTG ACACCTTCCT GGAACACATG TGCCGCCTGG ACATTGACTC CGCACCCATC 
ACGGCCCGCA ACACTGGGAT CATCTGTACC ATTGGCCCTG CTTCCCGATC TGTGGAGATG 
CTGAAGGAGA TGATTAAGTC TGGGATGAAT GTGGCTCGGC TGAATTTCTC TCATGGAACC 
CATGAGTACC ATGCAGAGAC TATCAAGAAT GTCCGTGCAG CCACAGAAAG CTTTGCATCT 
GATCCCATTC TCTACCGACC TGTTGCGGTG GCTCTGGATA CAAAGGGACC TGAGATCCGG 
ACTGGACTCA TCAAGGGCAG CGGCACCGCA GAGGTGGAGC TGAAGAAGGG AGCCACACTG 
AAGATCACCC TGGACAACGC CTACATGGAG AAGTGCGACG AGAACATCCT GTGGCTGGAC 
TATAAGAACA TCTGCAAGGT GGTGGAGGTG GGCAGCAAGA TCTACGTGGA CGATGGGCTC 
ATCTCCCTGC AGGTGAAGGA GAAAGGTGCT GACTACCTGG TGACAGAAGT GGAAAATGGT 
GGCTCCTTGG GCAGCAAGAA GGGCGTGAAC CTGCCTGGTG CTGCTGTGGA CCTCCCTGCT 
GTGTCAGAAA AGGACATCCA GGACCTGAAG TTTGGGGTGG AGCAGGACGT GGACATGGTG 
TTTGCGTCTT TCATCCGCAA GGCGGCTGAC GTGCATGAGG TTAGGAAGGT CCTGGGAGAG 
AAGGGCAAGA ACATCAAGAT CATCAGCAAA ATCGAGAACC ATGAAGGTGT CCGCAGGTTT 
GATGAGATTT TGGAGGCCAG CGATGGAATC ATGGTAGCTC GTGGTGACCT GGGCATTGAG 
ATTCCGGCAG AGAAGGTCTT CCTAGCTCAG AAGATGATGA TTGGACGATG CAACCGAGCT 
GGGAAGCCAG TCATCTGCGC CACCCAGATG CTGGAGAGCA TGATCAAGAA GCCACGCCCC 
ACCCGTGCTG AAGGCAGTGA CGTGGCCAAT GCAGTCCTAG ATGGAGCTGA CTGCATCATG 
CTGTCCGGAG AAACAGCCAA AGGGGACTAC CCTCTGGAGG CTGTTCGCAT GCAGCACCTG 
ATTGCCCGAG AGGCAGAGGC TGCCATCTAC CACTTGCAGT TATTCGAGGA ACTCCGCCGC 
CTGGCGCCCA TTACCAGCGA CCCCACAGAA GCTGCCGCCG TGGGTGCCGT GGAGGCCTCC 
TTCAAGTGCT GCAGTGGGGC CATTATCGTG CTCACCAAGT CTGGCAGGAG TGCTCACCAA 
GTGGCCCGGT ACCGCCCAAG GGCTCCTATC ATTGCTGTGA CACGCAATCC CCAGACAGCC 
CGCCAGGCCC ATCTGTACCG TGGCATCTTC CCTGTGCTGT GTAAGGATGC CGTACTGGAT 
GCCTGGGCTG AGGACGTTGA TCTTCGTGTG AACTTGGCCA TGAATGTTGG CAAGGCCCGA 
GGCTTCTTCA AGAAGGGAGA TGTGGTCATT GTGCTGACTG GATGGCGCCC TGGCTCTGGC 
TTCACCAACA CCATGCGTGT AGTGCCTGTA CCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006243250.2
CDS	294..1889
Translation	MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP

Target ORF information:

RefSeq Version	XM_006243188.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006243188.3

ORF Insert Sequence:

ATGCCCAAGC CAGACAGCGA AGCAGGGACT GCCTTCATTC AGACCCAGCA GCTCCATGCA 
GCCATGGCTG ACACCTTCCT GGAACACATG TGCCGCCTGG ACATTGACTC CGCACCCATC 
ACGGCCCGCA ACACTGGGAT CATCTGTACC ATTGGCCCTG CTTCCCGATC TGTGGAGATG 
CTGAAGGAGA TGATTAAGTC TGGGATGAAT GTGGCTCGGC TGAATTTCTC TCATGGAACC 
CATGAGTACC ATGCAGAGAC TATCAAGAAT GTCCGTGCAG CCACAGAAAG CTTTGCATCT 
GATCCCATTC TCTACCGACC TGTTGCGGTG GCTCTGGATA CAAAGGGACC TGAGATCCGG 
ACTGGACTCA TCAAGGGCAG CGGCACCGCA GAGGTGGAGC TGAAGAAGGG AGCCACACTG 
AAGATCACCC TGGACAACGC CTACATGGAG AAGTGCGACG AGAACATCCT GTGGCTGGAC 
TATAAGAACA TCTGCAAGGT GGTGGAGGTG GGCAGCAAGA TCTACGTGGA CGATGGGCTC 
ATCTCCCTGC AGGTGAAGGA GAAAGGTGCT GACTACCTGG TGACAGAAGT GGAAAATGGT 
GGCTCCTTGG GCAGCAAGAA GGGCGTGAAC CTGCCTGGTG CTGCTGTGGA CCTCCCTGCT 
GTGTCAGAAA AGGACATCCA GGACCTGAAG TTTGGGGTGG AGCAGGACGT GGACATGGTG 
TTTGCGTCTT TCATCCGCAA GGCGGCTGAC GTGCATGAGG TTAGGAAGGT CCTGGGAGAG 
AAGGGCAAGA ACATCAAGAT CATCAGCAAA ATCGAGAACC ATGAAGGTGT CCGCAGGTTT 
GATGAGATTT TGGAGGCCAG CGATGGAATC ATGGTAGCTC GTGGTGACCT GGGCATTGAG 
ATTCCGGCAG AGAAGGTCTT CCTAGCTCAG AAGATGATGA TTGGACGATG CAACCGAGCT 
GGGAAGCCAG TCATCTGCGC CACCCAGATG CTGGAGAGCA TGATCAAGAA GCCACGCCCC 
ACCCGTGCTG AAGGCAGTGA CGTGGCCAAT GCAGTCCTAG ATGGAGCTGA CTGCATCATG 
CTGTCCGGAG AAACAGCCAA AGGGGACTAC CCTCTGGAGG CTGTTCGCAT GCAGCACCTG 
ATTGCCCGAG AGGCAGAGGC TGCCATCTAC CACTTGCAGT TATTCGAGGA ACTCCGCCGC 
CTGGCGCCCA TTACCAGCGA CCCCACAGAA GCTGCCGCCG TGGGTGCCGT GGAGGCCTCC 
TTCAAGTGCT GCAGTGGGGC CATTATCGTG CTCACCAAGT CTGGCAGGAG TGCTCACCAA 
GTGGCCCGGT ACCGCCCAAG GGCTCCTATC ATTGCTGTGA CACGCAATCC CCAGACAGCC 
CGCCAGGCCC ATCTGTACCG TGGCATCTTC CCTGTGCTGT GTAAGGATGC CGTACTGGAT 
GCCTGGGCTG AGGACGTTGA TCTTCGTGTG AACTTGGCCA TGAATGTTGG CAAGGCCCGA 
GGCTTCTTCA AGAAGGGAGA TGTGGTCATT GTGCTGACTG GATGGCGCCC TGGCTCTGGC 
TTCACCAACA CCATGCGTGT AGTGCCTGTA CCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pkm ( XM_017595480.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450969.1 Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa62326
Clone ID Related Accession (Same CDS sequence)	XM_017595480.1
Accession Version	XM_017595480.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	pyruvate kinase PKM isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAACAG AAGCCCAGAC CCAGAGATCC AAAGGATCTC AGAAACCATG CCCAAGCCAG 
ACAGCGAAGC AGGGACTGCC TTCATTCAGA CCCAGCAGCT CCATGCAGCC ATGGCTGACA 
CCTTCCTGGA ACACATGTGC CGCCTGGACA TTGACTCCGC ACCCATCACG GCCCGCAACA 
CTGGGATCAT CTGTACCATT GTACCATGCA GAGACTATCA AGAATGTCCG TGCAGCCACA 
GAAAGCTTTG CATCTGATCC CATTCTCTAC CGACCTGTTG CGGTGGCTCT GGATACAAAG 
GGACCTGAGA TCCGGACTGG ACTCATCAAG GGCAGCGGCA CCGCAGAGGT GGAGCTGAAG 
AAGGGAGCCA CACTGAAGAT CACCCTGGAC AACGCCTACA TGGAGAAGTG CGACGAGAAC 
ATCCTGTGGC TGGACTATAA GAACATCTGC AAGGTGGTGG AGGTGGGCAG CAAGATCTAC 
GTGGACGATG GGCTCATCTC CCTGCAGGTG AAGGAGAAAG GTGCTGACTA CCTGGTGACA 
GAAGTGGAAA ATGGTGGCTC CTTGGGCAGC AAGAAGGGCG TGAACCTGCC TGGTGCTGCT 
GTGGACCTCC CTGCTGTGTC AGAAAAGGAC ATCCAGGACC TGAAGTTTGG GGTGGAGCAG 
GACGTGGACA TGGTGTTTGC GTCTTTCATC CGCAAGGCGG CTGACGTGCA TGAGGTTAGG 
AAGGTCCTGG GAGAGAAGGG CAAGAACATC AAGATCATCA GCAAAATCGA GAACCATGAA 
GGTGTCCGCA GGTTTGATGA GATTTTGGAG GCCAGCGATG GAATCATGGT AGCTCGTGGT 
GACCTGGGCA TTGAGATTCC GGCAGAGAAG GTCTTCCTAG CTCAGAAGAT GATGATTGGA 
CGATGCAACC GAGCTGGGAA GCCAGTCATC TGCGCCACCC AGATGCTGGA GAGCATGATC 
AAGAAGCCAC GCCCCACCCG TGCTGAAGGC AGTGACGTGG CCAATGCAGT CCTAGATGGA 
GCTGACTGCA TCATGCTGTC CGGAGAAACA GCCAAAGGGG ACTACCCTCT GGAGGCTGTT 
CGCATGCAGC ACCTGATTGC CCGAGAGGCA GAGGCTGCCA TCTACCACTT GCAGTTATTC 
GAGGAACTCC GCCGCCTGGC GCCCATTACC AGCGACCCCA CAGAAGCTGC CGCCGTGGGT 
GCCGTGGAGG CCTCCTTCAA GTGCTGCAGT GGGGCCATTA TCGTGCTCAC CAAGTCTGGC 
AGGAGTGCTC ACCAAGTGGC CCGGTACCGC CCAAGGGCTC CTATCATTGC TGTGACACGC 
AATCCCCAGA CAGCCCGCCA GGCCCATCTG TACCGTGGCA TCTTCCCTGT GCTGTGTAAG 
GATGCCGTAC TGGATGCCTG GGCTGAGGAC GTTGATCTTC GTGTGAACTT GGCCATGAAT 
GTTGGCAAGG CCCGAGGCTT CTTCAAGAAG GGAGATGTGG TCATTGTGCT GACTGGATGG 
CGCCCTGGCT CTGGCTTCAC CAACACCATG CGTGTAGTGC CTGTACCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450969.1
CDS	68..1618
Translation	MSTEAQTQRSKGSQKPCPSQTAKQGLPSFRPSSSMQPWLTPSWNTCAAWTLTPHPSRPATLGSSVPLYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP

Target ORF information:

RefSeq Version	XM_017595480.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pyruvate kinase, muscle (Pkm), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017595480.1

ORF Insert Sequence:

ATGTCAACAG AAGCCCAGAC CCAGAGATCC AAAGGATCTC AGAAACCATG CCCAAGCCAG 
ACAGCGAAGC AGGGACTGCC TTCATTCAGA CCCAGCAGCT CCATGCAGCC ATGGCTGACA 
CCTTCCTGGA ACACATGTGC CGCCTGGACA TTGACTCCGC ACCCATCACG GCCCGCAACA 
CTGGGATCAT CTGTACCATT GTACCATGCA GAGACTATCA AGAATGTCCG TGCAGCCACA 
GAAAGCTTTG CATCTGATCC CATTCTCTAC CGACCTGTTG CGGTGGCTCT GGATACAAAG 
GGACCTGAGA TCCGGACTGG ACTCATCAAG GGCAGCGGCA CCGCAGAGGT GGAGCTGAAG 
AAGGGAGCCA CACTGAAGAT CACCCTGGAC AACGCCTACA TGGAGAAGTG CGACGAGAAC 
ATCCTGTGGC TGGACTATAA GAACATCTGC AAGGTGGTGG AGGTGGGCAG CAAGATCTAC 
GTGGACGATG GGCTCATCTC CCTGCAGGTG AAGGAGAAAG GTGCTGACTA CCTGGTGACA 
GAAGTGGAAA ATGGTGGCTC CTTGGGCAGC AAGAAGGGCG TGAACCTGCC TGGTGCTGCT 
GTGGACCTCC CTGCTGTGTC AGAAAAGGAC ATCCAGGACC TGAAGTTTGG GGTGGAGCAG 
GACGTGGACA TGGTGTTTGC GTCTTTCATC CGCAAGGCGG CTGACGTGCA TGAGGTTAGG 
AAGGTCCTGG GAGAGAAGGG CAAGAACATC AAGATCATCA GCAAAATCGA GAACCATGAA 
GGTGTCCGCA GGTTTGATGA GATTTTGGAG GCCAGCGATG GAATCATGGT AGCTCGTGGT 
GACCTGGGCA TTGAGATTCC GGCAGAGAAG GTCTTCCTAG CTCAGAAGAT GATGATTGGA 
CGATGCAACC GAGCTGGGAA GCCAGTCATC TGCGCCACCC AGATGCTGGA GAGCATGATC 
AAGAAGCCAC GCCCCACCCG TGCTGAAGGC AGTGACGTGG CCAATGCAGT CCTAGATGGA 
GCTGACTGCA TCATGCTGTC CGGAGAAACA GCCAAAGGGG ACTACCCTCT GGAGGCTGTT 
CGCATGCAGC ACCTGATTGC CCGAGAGGCA GAGGCTGCCA TCTACCACTT GCAGTTATTC 
GAGGAACTCC GCCGCCTGGC GCCCATTACC AGCGACCCCA CAGAAGCTGC CGCCGTGGGT 
GCCGTGGAGG CCTCCTTCAA GTGCTGCAGT GGGGCCATTA TCGTGCTCAC CAAGTCTGGC 
AGGAGTGCTC ACCAAGTGGC CCGGTACCGC CCAAGGGCTC CTATCATTGC TGTGACACGC 
AATCCCCAGA CAGCCCGCCA GGCCCATCTG TACCGTGGCA TCTTCCCTGT GCTGTGTAAG 
GATGCCGTAC TGGATGCCTG GGCTGAGGAC GTTGATCTTC GTGTGAACTT GGCCATGAAT 
GTTGGCAAGG CCCGAGGCTT CTTCAAGAAG GGAGATGTGG TCATTGTGCT GACTGGATGG 
CGCCCTGGCT CTGGCTTCAC CAACACCATG CGTGTAGTGC CTGTACCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SIRT 1 binding with PKM and NSE and modulate their acetylation and activities.
Biochimica et biophysica acta. Proteins and proteomics1867(9)794-801(2019 09)
Zhang ZH,Zhang H,Wang YR,Liu XL,Huang H,Xu XH

PKM2 Involved in Neuronal Apoptosis on Hypoxic-ischemic Encephalopathy in Neonatal Rats.
Neurochemical research44(7)1602-1612(2019 Jul)
Wu Q,Ge W,Chen Y,Kong X,Xian H

Alpha-synuclein induces microglial migration via PKM2-dependent glycolysis.
International journal of biological macromolecules129601-607(2019 May)
Qiao H,He X,Zhang Q,Yuan H,Wang D,Li L,Hui Y,Wu Z,Li W,Zhang N

Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions.
World journal of gastroenterology25(16)1936-1949(2019 Apr)
Bi YH,Han WQ,Li RF,Wang YJ,Du ZS,Wang XJ,Jiang Y

JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting With Pyruvate Kinase M2 in Endothelial Cells.
Arteriosclerosis, thrombosis, and vascular biology36(7)1425-33(2016 07)
Boeckel JN,Derlet A,Glaser SF,Luczak A,Lucas T,Heumüller AW,Krüger M,Zehendner CM,Kaluza D,Doddaballapur A,Ohtani K,Treguer K,Dimmeler S

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Pkm cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM